Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_02554 (394 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|O01393|UNC9_CAEEL Innexin unc-9 (Uncoordinated protein 9) 57 1e-08 sp|Q23027|INX5_CAEEL Innexin-5 52 6e-07 sp|Q23157|INX11_CAEEL Innexin-11 49 5e-06 sp|Q27295|EAT5_CAEEL Innexin eat-5 45 4e-05 sp|Q23593|INX8_CAEEL Innexin-8 44 9e-05 sp|Q22549|INX10_CAEEL Innexin-10 42 6e-04 sp|Q19746|INX3_CAEEL Innexin-3 40 0.001 sp|Q03412|UNC7_CAEEL Innexin unc-7 (Uncoordinated protein 7) 36 0.024 sp|P33085|SHAKB_DROME Innexin shaking-B (Passover protein) 34 0.12 sp|O61788|INX17_CAEEL Innexin-17 (Gap junction innexin) 31 0.78
>sp|O01393|UNC9_CAEEL Innexin unc-9 (Uncoordinated protein 9) Length = 386 Score = 57.0 bits (136), Expect = 1e-08 Identities = 34/106 (32%), Positives = 60/106 (56%) Frame = +1 Query: 73 IASMMEHWLVQHREYRTGFSHRLKLRMYKFMKCFVISKRFATWLSFGYLTMKCLYLINSI 252 IA+ +E L H +++ +RLKL + + ++ ++F Y+++K LY +N + Sbjct: 159 IATNVEEAL--HVKHQVMSGNRLKL-----LNLIICTRSSGAAVTFLYISVKILYTVNIV 211 Query: 253 GQIFLMQAFLQLNNHDEYSSNFGLEIARNIFKGRNWEVTSVFPRVT 390 GQIFL+ F L N ++ +GL++ ++ GR WE + FPRVT Sbjct: 212 GQIFLLNTF--LGNRSKW---YGLQVLNDLMNGREWEESGHFPRVT 252
>sp|Q23027|INX5_CAEEL Innexin-5 Length = 447 Score = 51.6 bits (122), Expect = 6e-07 Identities = 40/127 (31%), Positives = 62/127 (48%), Gaps = 4/127 (3%) Frame = +1 Query: 22 LNVKHLVKISEKAEPAKIASMMEHWLVQHREYRTGFSHRLKLR----MYKFMKCFVISKR 189 L +K L +SE + KI S M V+ ++ F +L R ++K V S + Sbjct: 137 LKIKELAAVSEASR--KIKSNMSDDQVKATKFGRYFFKKLNFRNESPVFKETGSVVASGK 194 Query: 190 FATWLSFGYLTMKCLYLINSIGQIFLMQAFLQLNNHDEYSSNFGLEIARNIFKGRNWEVT 369 F L YL +K LYL N + Q +++ FL+ S +G + +++ GR WE T Sbjct: 195 FLPAL---YLLVKILYLANIVLQFWILTYFLETK-----SWMWGWQTFQDLMAGREWETT 246 Query: 370 SVFPRVT 390 +FPRVT Sbjct: 247 GIFPRVT 253
>sp|Q23157|INX11_CAEEL Innexin-11 Length = 465 Score = 48.5 bits (114), Expect = 5e-06 Identities = 29/85 (34%), Positives = 44/85 (51%), Gaps = 2/85 (2%) Frame = +1 Query: 136 RLKLRMYKFMKC--FVISKRFATWLSFGYLTMKCLYLINSIGQIFLMQAFLQLNNHDEYS 309 R K++++K + F S F +W+ YL K LY +N Q++LM FL N H Y Sbjct: 177 RKKVQVHKTVTFLNFQYSSGFISWI---YLFTKVLYFLNVFAQLYLMNYFLGTNRHHWY- 232 Query: 310 SNFGLEIARNIFKGRNWEVTSVFPR 384 G + ++I +G WE + FPR Sbjct: 233 ---GFGVVQDIVQGEPWERSGYFPR 254
>sp|Q27295|EAT5_CAEEL Innexin eat-5 Length = 423 Score = 45.4 bits (106), Expect = 4e-05 Identities = 35/128 (27%), Positives = 59/128 (46%), Gaps = 4/128 (3%) Frame = +1 Query: 16 TGLNVKHLVKISEKAEPAKIASMMEHWLVQHREYRTGFSHRLK----LRMYKFMKCFVIS 183 +G+N+ LV+ ++KAE A+ + + R R +M K + F Sbjct: 126 SGINIIKLVETAQKAEGAESEERKKQIDIICRHISNNLRKRRNEEETTKMAKIQRIF--G 183 Query: 184 KRFATWLSFGYLTMKCLYLINSIGQIFLMQAFLQLNNHDEYSSNFGLEIARNIFKGRNWE 363 + +++ YL K +Y+ NS Q + FL N D Y +G+ I +I KG +WE Sbjct: 184 MQHGKYITNVYLVTKLIYMTNSFLQFYSTNKFLGQN--DPY---WGMRILDDILKGTDWE 238 Query: 364 VTSVFPRV 387 + FPR+ Sbjct: 239 HSGNFPRI 246
>sp|Q23593|INX8_CAEEL Innexin-8 Length = 382 Score = 44.3 bits (103), Expect = 9e-05 Identities = 27/86 (31%), Positives = 43/86 (50%), Gaps = 5/86 (5%) Frame = +1 Query: 151 MYKFMKCFVISKRFATWLSF-----GYLTMKCLYLINSIGQIFLMQAFLQLNNHDEYSSN 315 M +FM+ + S + SF Y +K LYL+N+I Q ++ FL + + Sbjct: 159 MARFMRTKITSVHTPSLFSFIRMYMVYSVIKILYLVNAIAQFVIIAIFLG----QKRNLF 214 Query: 316 FGLEIARNIFKGRNWEVTSVFPRVTY 393 +G + N+ G WE T +FPRVT+ Sbjct: 215 WGWTLFMNLLNGITWETTGLFPRVTF 240
>sp|Q22549|INX10_CAEEL Innexin-10 Length = 559 Score = 41.6 bits (96), Expect = 6e-04 Identities = 34/130 (26%), Positives = 59/130 (45%), Gaps = 5/130 (3%) Frame = +1 Query: 16 TGLNVKHLVKISEKAEPAK--IASMMEHWLVQHREYRTGFSHRLK---LRMYKFMKCFVI 180 +G+ + +VK+S K I L H + F RL+ +R ++F+ F + Sbjct: 129 SGIKINEIVKLSSDPNNIKPDIKRANIKSLTVHLQGALRFHRRLQKKQIRPHRFLWLFNL 188 Query: 181 SKRFATWLSFGYLTMKCLYLINSIGQIFLMQAFLQLNNHDEYSSNFGLEIARNIFKGRNW 360 A +++ YL K YL N Q+ M FL+ + + Y G+ ++ G W Sbjct: 189 PYS-AFFVTAMYLCTKFFYLANVCLQLMFMNRFLETDKYKWY----GMGALVDLLNGTTW 243 Query: 361 EVTSVFPRVT 390 E + +FPRV+ Sbjct: 244 EQSGMFPRVS 253
>sp|Q19746|INX3_CAEEL Innexin-3 Length = 420 Score = 40.4 bits (93), Expect = 0.001 Identities = 21/74 (28%), Positives = 35/74 (47%) Frame = +1 Query: 169 CFVISKRFATWLSFGYLTMKCLYLINSIGQIFLMQAFLQLNNHDEYSSNFGLEIARNIFK 348 C+ K + S Y+ +K +YL N Q ++ FL + +G +++ Sbjct: 180 CYRFGKGLGSMTSMLYICIKLMYLANVFVQFIILNKFL-----GNETFLWGFHTFADLYA 234 Query: 349 GRNWEVTSVFPRVT 390 GR W+ + VFPRVT Sbjct: 235 GREWQDSGVFPRVT 248
>sp|Q03412|UNC7_CAEEL Innexin unc-7 (Uncoordinated protein 7) Length = 522 Score = 36.2 bits (82), Expect = 0.024 Identities = 19/59 (32%), Positives = 30/59 (50%) Frame = +1 Query: 214 YLTMKCLYLINSIGQIFLMQAFLQLNNHDEYSSNFGLEIARNIFKGRNWEVTSVFPRVT 390 Y+ +K LY N + Q FL+ L N+ +G + +++ WE T +FPRVT Sbjct: 322 YIGIKVLYSANVLLQFFLLNHLLGSND-----LAYGFSLLKDLMHAIEWEQTGMFPRVT 375
>sp|P33085|SHAKB_DROME Innexin shaking-B (Passover protein) Length = 372 Score = 33.9 bits (76), Expect = 0.12 Identities = 23/71 (32%), Positives = 34/71 (47%), Gaps = 3/71 (4%) Frame = +1 Query: 187 RFATWLSFGYLTMKCLYLINSIGQIFLMQAFLQLNNHDEYSSNFGLEI---ARNIFKGRN 357 R+ W ++ Y + L LIN IGQ+FLM F D FGL++ + R Sbjct: 172 RYHNWWAYRYYVCELLALINVIGQMFLMNRFF-----DGEFITFGLKVIDYMETDQEDRM 226 Query: 358 WEVTSVFPRVT 390 + +FPR+T Sbjct: 227 DPMIYIFPRMT 237
>sp|O61788|INX17_CAEEL Innexin-17 (Gap junction innexin) Length = 362 Score = 31.2 bits (69), Expect = 0.78 Identities = 11/26 (42%), Positives = 18/26 (69%) Frame = +1 Query: 316 FGLEIARNIFKGRNWEVTSVFPRVTY 393 +G I ++I +GR W+ + FPRVT+ Sbjct: 212 YGWTITKDILQGRQWQESGSFPRVTF 237
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 40,542,202 Number of Sequences: 369166 Number of extensions: 659935 Number of successful extensions: 1546 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 1531 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 1541 length of database: 68,354,980 effective HSP length: 96 effective length of database: 50,620,420 effective search space used: 1721094280 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)