Planaria EST Database


DrC_02544

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_02544
         (820 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|O18404|HCD2_DROME  3-hydroxyacyl-CoA dehydrogenase type I...   265   1e-70
sp|Q99714|HCD2_HUMAN  3-hydroxyacyl-CoA dehydrogenase type I...   248   1e-65
sp|O02691|HCD2_BOVIN  3-hydroxyacyl-CoA dehydrogenase type I...   246   4e-65
sp|O70351|HCD2_RAT  3-hydroxyacyl-CoA dehydrogenase type II ...   246   4e-65
sp|O08756|HCD2_MOUSE  3-hydroxyacyl-CoA dehydrogenase type I...   243   4e-64
sp|Q9X248|FABG_THEMA  3-oxoacyl-[acyl-carrier-protein] reduc...   102   2e-21
sp|P51831|FABG_BACSU  3-oxoacyl-[acyl-carrier-protein] reduc...    97   4e-20
sp|P28643|FABG_CUPLA  3-oxoacyl-[acyl-carrier-protein] reduc...    93   1e-18
sp|O67610|FABG_AQUAE  3-oxoacyl-[acyl-carrier-protein] reduc...    93   1e-18
sp|P99093|FABG_STAAN  3-oxoacyl-[acyl-carrier-protein] reduc...    92   2e-18
>sp|O18404|HCD2_DROME 3-hydroxyacyl-CoA dehydrogenase type II (Type II HADH) (Scully
           protein)
          Length = 255

 Score =  265 bits (676), Expect = 1e-70
 Identities = 133/235 (56%), Positives = 166/235 (70%), Gaps = 7/235 (2%)
 Frame = +1

Query: 73  TVERLTKQGCKVAICDL------QEPKTLPSNSYFIKTDVSSENDVENALTQIKSMAQKL 234
           T ERL KQG  V + DL      +  K L     F+  DV+SE DV  AL   K    +L
Sbjct: 20  TAERLAKQGASVILADLPSSKGNEVAKELGDKVVFVPVDVTSEKDVSAALQTAKDKFGRL 79

Query: 235 DILVNCAGVGLAVKVFN-RKEIPHPLHDFERILKVNTVGTFNMIRLCCSMFISNVPNEFD 411
           D+ VNCAG   AVK FN  K + H L DF+R++ +NTVGTFN+IRL   +  +N PN+  
Sbjct: 80  DLTVNCAGTATAVKTFNFNKNVAHRLEDFQRVININTVGTFNVIRLSAGLMGANEPNQDG 139

Query: 412 QRGIVINTSSIAAFDGQSGQSAYSASKAAIAGMTLPLARDLAAMGVRVMTIAPGLFLTPL 591
           QRG+++NT+S+AAFDGQ GQ+AYSASKAA+ GMTLP+ARDL+  G+R+ TIAPGLF TP+
Sbjct: 140 QRGVIVNTASVAAFDGQIGQAAYSASKAAVVGMTLPIARDLSTQGIRICTIAPGLFNTPM 199

Query: 592 LEALPNNVQAHLSTTVPFPSRLGHPDEFAHLVQTIIENPMLNGEVIRIDGALRMM 756
           L ALP  V+  L+ ++PFP RLG P E+AHLVQ I ENP+LNGEVIRIDGALRMM
Sbjct: 200 LAALPEKVRTFLAKSIPFPQRLGEPSEYAHLVQAIYENPLLNGEVIRIDGALRMM 254
>sp|Q99714|HCD2_HUMAN 3-hydroxyacyl-CoA dehydrogenase type II (Type II HADH) (Endoplasmic
           reticulum-associated amyloid beta-peptide binding
           protein) (Short-chain type dehydrogenase/reductase
           XH98G2)
          Length = 261

 Score =  248 bits (634), Expect = 1e-65
 Identities = 130/234 (55%), Positives = 163/234 (69%), Gaps = 7/234 (2%)
 Frame = +1

Query: 73  TVERLTKQGCKVAICDLQ------EPKTLPSNSYFIKTDVSSENDVENALTQIKSMAQKL 234
           T ERL  QG    + DL       + K L +N  F   DV+SE DV+ AL   K    ++
Sbjct: 26  TAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQTALALAKGKFGRV 85

Query: 235 DILVNCAGVGLAVKVFN-RKEIPHPLHDFERILKVNTVGTFNMIRLCCSMFISNVPNEFD 411
           D+ VNCAG+ +A K +N +K   H L DF+R+L VN +GTFN+IRL       N P++  
Sbjct: 86  DVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGG 145

Query: 412 QRGIVINTSSIAAFDGQSGQSAYSASKAAIAGMTLPLARDLAAMGVRVMTIAPGLFLTPL 591
           QRG++INT+S+AAF+GQ GQ+AYSASK  I GMTLP+ARDLA +G+RVMTIAPGLF TPL
Sbjct: 146 QRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPL 205

Query: 592 LEALPNNVQAHLSTTVPFPSRLGHPDEFAHLVQTIIENPMLNGEVIRIDGALRM 753
           L +LP  V   L++ VPFPSRLG P E+AHLVQ IIENP LNGEVIR+DGA+RM
Sbjct: 206 LTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIENPFLNGEVIRLDGAIRM 259
>sp|O02691|HCD2_BOVIN 3-hydroxyacyl-CoA dehydrogenase type II (Type II HADH)
          Length = 261

 Score =  246 bits (629), Expect = 4e-65
 Identities = 128/234 (54%), Positives = 163/234 (69%), Gaps = 7/234 (2%)
 Frame = +1

Query: 73  TVERLTKQGCKVAICDLQ------EPKTLPSNSYFIKTDVSSENDVENALTQIKSMAQKL 234
           T ERL  QG    + DL       + K L  +  F   DV+SE DV+ ALT  +    ++
Sbjct: 26  TAERLVGQGATAVLLDLPNSDGETQAKKLGKSCAFAPADVTSEKDVQAALTLAREKFGRV 85

Query: 235 DILVNCAGVGLAVKVFN-RKEIPHPLHDFERILKVNTVGTFNMIRLCCSMFISNVPNEFD 411
           D+ VNCAG+ +A K +N +K   H L DF+R++ VN +GTFN+IRL       N P++  
Sbjct: 86  DVAVNCAGIAVASKTYNLKKSQAHTLEDFQRVINVNLIGTFNVIRLVAGEMGQNEPDQGG 145

Query: 412 QRGIVINTSSIAAFDGQSGQSAYSASKAAIAGMTLPLARDLAAMGVRVMTIAPGLFLTPL 591
           QRG++INT+S+AAF+GQ GQ+AYSASK  I GMTLP+ARDLA MG+RVMTIAPGLF TPL
Sbjct: 146 QRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPMGIRVMTIAPGLFGTPL 205

Query: 592 LEALPNNVQAHLSTTVPFPSRLGHPDEFAHLVQTIIENPMLNGEVIRIDGALRM 753
           L  LP+ V+  L++ VPFPSRLG P E+AHLVQ IIEN  LNGEVIR+DGA+RM
Sbjct: 206 LTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQAIIENSFLNGEVIRLDGAIRM 259
>sp|O70351|HCD2_RAT 3-hydroxyacyl-CoA dehydrogenase type II (Type II HADH) (Endoplasmic
           reticulum-associated amyloid beta-peptide binding
           protein)
          Length = 261

 Score =  246 bits (629), Expect = 4e-65
 Identities = 124/234 (52%), Positives = 166/234 (70%), Gaps = 7/234 (2%)
 Frame = +1

Query: 73  TVERLTKQGCKVAICDLQ------EPKTLPSNSYFIKTDVSSENDVENALTQIKSMAQKL 234
           T +RL  QG    + D+       E K L  N  F   +V+SE +V+ ALT  K    ++
Sbjct: 26  TAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQAALTLAKEKFGRI 85

Query: 235 DILVNCAGVGLAVKVFNRKEIP-HPLHDFERILKVNTVGTFNMIRLCCSMFISNVPNEFD 411
           D+ VNCAG+ +A+K ++ K+   H L DF+R++ VN +GTFN+IRL   +   N P++  
Sbjct: 86  DVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIRLVAGVMGQNEPDQGG 145

Query: 412 QRGIVINTSSIAAFDGQSGQSAYSASKAAIAGMTLPLARDLAAMGVRVMTIAPGLFLTPL 591
           QRG++INT+S+AAF+GQ GQ+AYSASK  I GMTLP+ARDLA +G+RV+TIAPGLF TPL
Sbjct: 146 QRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVVTIAPGLFATPL 205

Query: 592 LEALPNNVQAHLSTTVPFPSRLGHPDEFAHLVQTIIENPMLNGEVIRIDGALRM 753
           L  LP+ V+  L++ VPFPSRLG P E+AHLVQ +IENP LNGEVIR+DGA+RM
Sbjct: 206 LTTLPDKVRNFLASQVPFPSRLGDPAEYAHLVQMVIENPFLNGEVIRLDGAIRM 259
>sp|O08756|HCD2_MOUSE 3-hydroxyacyl-CoA dehydrogenase type II (Type II HADH) (Endoplasmic
           reticulum-associated amyloid beta-peptide binding
           protein)
          Length = 261

 Score =  243 bits (621), Expect = 4e-64
 Identities = 123/234 (52%), Positives = 165/234 (70%), Gaps = 7/234 (2%)
 Frame = +1

Query: 73  TVERLTKQGCKVAICDL------QEPKTLPSNSYFIKTDVSSENDVENALTQIKSMAQKL 234
           T +RL  QG    + D+       + K L  +  F   +V+SE +++ ALT  K    ++
Sbjct: 26  TAKRLVGQGATAVLLDVPDSEGESQAKKLGESCIFAPANVTSEKEIQAALTLAKEKFGRI 85

Query: 235 DILVNCAGVGLAVKVFNRKEIP-HPLHDFERILKVNTVGTFNMIRLCCSMFISNVPNEFD 411
           D+ VNCAG+ +A+K +++K+   H L DF+R++ VN +GTFN+IRL       N P++  
Sbjct: 86  DVAVNCAGIAVAIKTYHQKKNKIHTLEDFQRVINVNLIGTFNVIRLVAGEMGQNEPDQGG 145

Query: 412 QRGIVINTSSIAAFDGQSGQSAYSASKAAIAGMTLPLARDLAAMGVRVMTIAPGLFLTPL 591
           QRG++INT+S+AAF+GQ GQ+AYSASK  I GMTLP+ARDLA  G+RV+TIAPGLF TPL
Sbjct: 146 QRGVIINTASVAAFEGQVGQAAYSASKGGIDGMTLPIARDLAPTGIRVVTIAPGLFATPL 205

Query: 592 LEALPNNVQAHLSTTVPFPSRLGHPDEFAHLVQTIIENPMLNGEVIRIDGALRM 753
           L  LP  V+  L++ VPFPSRLG P E+AHLVQTIIENP LNGEVIR+DGA+RM
Sbjct: 206 LTTLPEKVRNFLASQVPFPSRLGDPAEYAHLVQTIIENPFLNGEVIRLDGAIRM 259
>sp|Q9X248|FABG_THEMA 3-oxoacyl-[acyl-carrier-protein] reductase (3-ketoacyl-acyl carrier
           protein reductase)
          Length = 246

 Score =  102 bits (253), Expect = 2e-21
 Identities = 64/212 (30%), Positives = 108/212 (50%), Gaps = 3/212 (1%)
 Frame = +1

Query: 121 LQEPKTLPSNSYFIKTDVSSENDVENALTQIKSMAQKLDILVNCAGVGLAVKVFNRKEIP 300
           ++E + LP        +V+  + ++  + ++     ++D+LVN AG+     +   KE  
Sbjct: 46  VKEAEGLPGKVDPYVLNVTDRDQIKEVVEKVVQKYGRIDVLVNNAGITRDALLVRMKE-- 103

Query: 301 HPLHDFERILKVNTVGTFNMIRLCCSMFISNVPNEFDQR-GIVINTSSIAAFDGQSGQSA 477
               D++ ++ VN  G FN+ ++        VP    QR G ++N SS+    G  GQ+ 
Sbjct: 104 ---EDWDAVINVNLKGVFNVTQMV-------VPYMIKQRNGSIVNVSSVVGIYGNPGQTN 153

Query: 478 YSASKAAIAGMTLPLARDLAAMGVRVMTIAPGLFLTPLLEALPNNVQAHLSTTVPFPSRL 657
           Y+ASKA + GMT   A++LA   +RV  +APG   TP+ E LP   +    + +P   R 
Sbjct: 154 YAASKAGVIGMTKTWAKELAGRNIRVNAVAPGFIETPMTEKLPEKARETALSRIPL-GRF 212

Query: 658 GHPDEFAHLVQTII--ENPMLNGEVIRIDGAL 747
           G P+E A ++  +   E+  + G+VI IDG L
Sbjct: 213 GKPEEVAQVILFLASDESSYVTGQVIGIDGGL 244
>sp|P51831|FABG_BACSU 3-oxoacyl-[acyl-carrier-protein] reductase (3-ketoacyl-acyl carrier
           protein reductase)
          Length = 246

 Score = 97.4 bits (241), Expect = 4e-20
 Identities = 60/213 (28%), Positives = 105/213 (49%), Gaps = 2/213 (0%)
 Frame = +1

Query: 121 LQEPKTLPSNSYFIKTDVSSENDVENALTQIKSMAQKLDILVNCAGVGLAVKVFNRKEIP 300
           + E K++   +  +K DVS+  DV+N + +  S+   +DILVN AG+     +   KE  
Sbjct: 46  VDEIKSMGRKAIAVKADVSNPEDVQNMIKETLSVFSTIDILVNNAGITRDNLIMRMKE-- 103

Query: 301 HPLHDFERILKVNTVGTFNMIRLCCSMFISNVPNEFDQRGIVINTSSIAAFDGQSGQSAY 480
               +++ ++ +N  G FN  +      +        + G +IN SSI    G  GQ+ Y
Sbjct: 104 ---DEWDDVININLKGVFNCTKAVTRQMMKQ------RSGRIINVSSIVGVSGNPGQANY 154

Query: 481 SASKAAIAGMTLPLARDLAAMGVRVMTIAPGLFLTPLLEALPNNVQAHLSTTVPFPSRLG 660
            A+KA + G+T   A++LA+  + V  IAPG   T + + L  +VQ  +   +P  +R G
Sbjct: 155 VAAKAGVIGLTKSSAKELASRNITVNAIAPGFISTDMTDKLAKDVQDEMLKQIPL-ARFG 213

Query: 661 HPDEFAHLVQTIIEN--PMLNGEVIRIDGALRM 753
            P + + +V  +       + G+ + IDG + M
Sbjct: 214 EPSDVSSVVTFLASEGARYMTGQTLHIDGGMVM 246
>sp|P28643|FABG_CUPLA 3-oxoacyl-[acyl-carrier-protein] reductase, chloroplast precursor
           (3-ketoacyl-acyl carrier protein reductase)
          Length = 320

 Score = 92.8 bits (229), Expect = 1e-18
 Identities = 66/236 (27%), Positives = 109/236 (46%), Gaps = 13/236 (5%)
 Frame = +1

Query: 85  LTKQGCKVAICDLQEPKTLPSNSYFIKT----------DVSSENDVENALTQIKSMAQKL 234
           L K GCKV +   +  K     S  I+           DVS E DVE  +         +
Sbjct: 97  LGKAGCKVLVNYARSSKEAEEVSKEIEAFGGQALTFGGDVSKEEDVEAMIKTAVDAWGTV 156

Query: 235 DILVNCAGVGLAVKVFNRKEIPHPLHDFERILKVNTVGTFNMIRLCCSMFISNVPNEFDQ 414
           DILVN AG+     +   K+       ++ ++ +N  G F   +    + +        +
Sbjct: 157 DILVNNAGITRDGLLMRMKK-----SQWQEVIDLNLTGVFLCTQAAAKIMMKK------K 205

Query: 415 RGIVINTSSIAAFDGQSGQSAYSASKAAIAGMTLPLARDLAAMGVRVMTIAPGLFLTPLL 594
           +G +IN +S+    G +GQ+ YSA+KA + G T  +AR+ A+  + V  +APG   + + 
Sbjct: 206 KGRIINIASVVGLVGNAGQANYSAAKAGVIGFTKTVAREYASRNINVNAVAPGFISSDMT 265

Query: 595 EALPNNVQAHLSTTVPFPSRLGHPDEFAHLVQTIIENP---MLNGEVIRIDGALRM 753
             L +++   +  T+P   R G P+E A LV+ +  NP    + G+V  IDG + M
Sbjct: 266 SKLGDDINKKILETIPL-GRYGQPEEVAGLVEFLAINPASSYVTGQVFTIDGGMTM 320
>sp|O67610|FABG_AQUAE 3-oxoacyl-[acyl-carrier-protein] reductase (3-ketoacyl-acyl carrier
           protein reductase)
          Length = 248

 Score = 92.8 bits (229), Expect = 1e-18
 Identities = 62/198 (31%), Positives = 98/198 (49%), Gaps = 2/198 (1%)
 Frame = +1

Query: 160 IKTDVSSENDVENALTQIKSMAQKLDILVNCAGVGLAVKVFNRKEIPHPLHDFERILKVN 339
           ++ ++ SE  +  A  +I ++   +DILVN AG+    K+F R      L D+E +LKVN
Sbjct: 62  VEMNLLSEESINKAFEEIYNLVDGIDILVNNAGI-TRDKLFLRMS----LLDWEEVLKVN 116

Query: 340 TVGTFNMIRLCCSMFISNVPNEFDQRGIVINTSSIAAFDGQSGQSAYSASKAAIAGMTLP 519
             GTF + +      I        + G ++N SS+  F G  GQ  YS +KA + G T  
Sbjct: 117 LTGTFLVTQNSLRKMIK------QRWGRIVNISSVVGFTGNVGQVNYSTTKAGLIGFTKS 170

Query: 520 LARDLAAMGVRVMTIAPGLFLTPLLEALPNNVQAHLSTTVPFPSRLGHPDEFAHLVQTII 699
           LA++LA   V V  +APG   T +   L   ++      +P   R G P+E A++V  + 
Sbjct: 171 LAKELAPRNVLVNAVAPGFIETDMTAVLSEEIKQKYKEQIPL-GRFGSPEEVANVVLFLC 229

Query: 700 EN--PMLNGEVIRIDGAL 747
                 + GEVI ++G +
Sbjct: 230 SELASYITGEVIHVNGGM 247
>sp|P99093|FABG_STAAN 3-oxoacyl-[acyl-carrier-protein] reductase (3-ketoacyl-acyl carrier
           protein reductase)
 sp|P0A0I0|FABG_STAAW 3-oxoacyl-[acyl-carrier-protein] reductase (3-ketoacyl-acyl carrier
           protein reductase)
 sp|P0A0H9|FABG_STAAM 3-oxoacyl-[acyl-carrier-protein] reductase (3-ketoacyl-acyl carrier
           protein reductase)
 sp|Q6GHK4|FABG_STAAR 3-oxoacyl-[acyl-carrier-protein] reductase (3-ketoacyl-acyl carrier
           protein reductase)
 sp|Q6G9Y2|FABG_STAAS 3-oxoacyl-[acyl-carrier-protein] reductase (3-ketoacyl-acyl carrier
           protein reductase)
          Length = 246

 Score = 92.0 bits (227), Expect = 2e-18
 Identities = 59/214 (27%), Positives = 110/214 (51%), Gaps = 3/214 (1%)
 Frame = +1

Query: 121 LQEPKTLPSNSYFIKTDVSSENDVENALTQIKSMAQKLDILVNCAGVGLAVKVFNRKEIP 300
           ++E K    +S+ I+ +V+  ++V+  + ++ S    LD+LVN AG+     +   KE  
Sbjct: 46  VEEIKAKGVDSFAIQANVADADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMRMKE-- 103

Query: 301 HPLHDFERILKVNTVGTFNMIRLCCSMFISNVPNEFDQR-GIVINTSSIAAFDGQSGQSA 477
               +++ ++  N  G FN I+          P    QR G +IN SS+    G  GQ+ 
Sbjct: 104 ---QEWDDVIDTNLKGVFNCIQKA-------TPQMLRQRSGAIINLSSVVGAVGNPGQAN 153

Query: 478 YSASKAAIAGMTLPLARDLAAMGVRVMTIAPGLFLTPLLEALPNNVQAHLSTTVPFPSRL 657
           Y A+KA + G+T   AR+LA+ G+ V  +APG  ++ + +AL + ++  + T +P  +R 
Sbjct: 154 YVATKAGVIGLTKSAARELASRGITVNAVAPGFIVSDMTDALSDELKEQMLTQIPL-ARF 212

Query: 658 GHPDEFAHLVQTIIEN--PMLNGEVIRIDGALRM 753
           G   + A+ V  +  +    + G+ I ++G + M
Sbjct: 213 GQDTDIANTVAFLASDKAKYITGQTIHVNGGMYM 246
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 91,565,659
Number of Sequences: 369166
Number of extensions: 1839323
Number of successful extensions: 5509
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5187
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5346
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7859674995
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)