Planaria EST Database


DrC_02529

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_02529
         (856 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q13114|TRAF3_HUMAN  TNF receptor-associated factor 3 (CD4...    97   7e-20
sp|Q9Y4K3|TRAF6_HUMAN  TNF receptor-associated factor 6 (Int...    96   1e-19
sp|Q60803|TRAF3_MOUSE  TNF receptor-associated factor 3 (CD4...    96   1e-19
sp|P70196|TRAF6_MOUSE  TNF receptor-associated factor 6            96   2e-19
sp|Q61382|TRAF4_MOUSE  TNF receptor-associated factor 4 (Cys...    95   2e-19
sp|O00463|TRAF5_HUMAN  TNF receptor-associated factor 5 (RIN...    91   4e-18
sp|Q12933|TRAF2_HUMAN  TNF receptor-associated factor 2 (Tum...    90   7e-18
sp|Q9BUZ4|TRAF4_HUMAN  TNF receptor-associated factor 4 (Cys...    90   9e-18
sp|P39429|TRAF2_MOUSE  TNF receptor-associated factor 2            90   9e-18
sp|P70191|TRAF5_MOUSE  TNF receptor-associated factor 5            81   4e-15
>sp|Q13114|TRAF3_HUMAN TNF receptor-associated factor 3 (CD40 receptor associated factor
           1) (CRAF1) (CD40 binding protein) (CD40BP) (LMP1
           associated protein) (LAP1) (CAP-1)
          Length = 568

 Score = 96.7 bits (239), Expect = 7e-20
 Identities = 61/206 (29%), Positives = 94/206 (45%), Gaps = 10/206 (4%)
 Frame = +3

Query: 141 KKNFPFNISDNLKCIICTQLLLNALQTDCGCRYCQICLDEYMGQGKKKCLTEGCGDI--- 311
           K+ F   + D  KC  C  +L +  QT+CG R+C+ C+   +     KC    C +    
Sbjct: 40  KEKFVKTVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSSSPKCTA--CQESIVK 97

Query: 312 SRTISDNAVNREIGQLKVKCLFSA--CKYEGLLRDIGDHL-DSCVHQLVSC--PECNEEL 476
            +   DN   REI  L++ C   +  C  +  L  +  HL + C  + + C  P+C E++
Sbjct: 98  DKVFKDNCCKREILALQIYCRNESRGCAEQLTLGHLLVHLKNDCHFEELPCVRPDCKEKV 157

Query: 477 PKNDLKDHLEKNCQMRLVNCKHCGEIMAYQTLDKSHLDPKNENICPKLEGFCPYKCDNKK 656
            + DL+DH+EK C+ R   C HC   +    L K       +  CP +   CP+KC  + 
Sbjct: 158 LRKDLRDHVEKACKYREATCSHCKSQVPMIALQK-----HEDTDCPCVVVSCPHKCSVQT 212

Query: 657 IV--NLLNHRKECSKKPITCPFSVIG 728
           ++   L  H  EC   P TC F   G
Sbjct: 213 LLRSELSAHLSECVNAPSTCSFKRYG 238
>sp|Q9Y4K3|TRAF6_HUMAN TNF receptor-associated factor 6 (Interleukin 1 signal transducer)
           (RING finger protein 85)
          Length = 522

 Score = 95.9 bits (237), Expect = 1e-19
 Identities = 62/194 (31%), Positives = 89/194 (45%), Gaps = 5/194 (2%)
 Frame = +3

Query: 162 ISDNLKCIICTQLLLNALQTDCGCRYCQICLDEYMGQGKKKCLTEGCGDI---SRTISDN 332
           +    +C IC   L  A+QT CG R+C+ C+ + +     KC  +   +I   ++   DN
Sbjct: 64  LESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVDN--EILLENQLFPDN 121

Query: 333 AVNREIGQLKVKCLFSACKYEGLLRDIGDHLDSCVHQLVSCPECNEELPKNDLKDHLEKN 512
              REI  L VKC    C ++  LR + DH   C   L+ CP+C     K  +  H+ K+
Sbjct: 122 FAKREILSLMVKCPNEGCLHKMELRHLEDHQAHCEFALMDCPQCQRPFQKFHINIHILKD 181

Query: 513 CQMRLVNCKHCGEIMAYQTLDKSHLDPKNENICPKLEGFCPYKCDNKKI-VNLLNHRK-E 686
           C  R V+C +C   MA++  DK   D      CP     C Y C+   I   + NH   +
Sbjct: 182 CPRRQVSCDNCAASMAFE--DKEIHDQN----CPLANVICEY-CNTILIREQMPNHYDLD 234

Query: 687 CSKKPITCPFSVIG 728
           C   PI C FS  G
Sbjct: 235 CPTAPIPCTFSTFG 248
>sp|Q60803|TRAF3_MOUSE TNF receptor-associated factor 3 (CD40 receptor associated factor
           1) (CRAF1) (TRAFAMN)
          Length = 567

 Score = 95.9 bits (237), Expect = 1e-19
 Identities = 62/206 (30%), Positives = 92/206 (44%), Gaps = 10/206 (4%)
 Frame = +3

Query: 141 KKNFPFNISDNLKCIICTQLLLNALQTDCGCRYCQICLDEYMGQGKKKCLTEGCGDI--- 311
           K+ F   + D  KC  C  +L N  QT+CG R+C+ C+   +     KC    C +    
Sbjct: 39  KEKFVKTVEDKYKCEKCRLVLCNPKQTECGHRFCESCMAALLSSSSPKC--TACQESIIK 96

Query: 312 SRTISDNAVNREIGQLKVKCLFS--ACKYEGLLRDIGDHL-DSCVHQLVSC--PECNEEL 476
            +   DN   REI  L+V C      C  +  L  +  HL + C  + + C   +C E++
Sbjct: 97  DKVFKDNCCKREILALQVYCRNEGRGCAEQLTLGHLLVHLKNECQFEELPCLRADCKEKV 156

Query: 477 PKNDLKDHLEKNCQMRLVNCKHCGEIMAYQTLDKSHLDPKNENICPKLEGFCPYKCDNKK 656
            + DL+DH+EK C+ R   C HC   +    L K       +  CP +   CP+KC  + 
Sbjct: 157 LRKDLRDHVEKACKYREATCSHCKSQVPMIKLQK-----HEDTDCPCVVVSCPHKCSVQT 211

Query: 657 IV--NLLNHRKECSKKPITCPFSVIG 728
           ++   L  H  EC   P TC F   G
Sbjct: 212 LLRSELSAHLSECVNAPSTCSFKRYG 237
>sp|P70196|TRAF6_MOUSE TNF receptor-associated factor 6
          Length = 530

 Score = 95.5 bits (236), Expect = 2e-19
 Identities = 61/194 (31%), Positives = 89/194 (45%), Gaps = 5/194 (2%)
 Frame = +3

Query: 162 ISDNLKCIICTQLLLNALQTDCGCRYCQICLDEYMGQGKKKCLTEGCGDI---SRTISDN 332
           +    +C IC   L  A+QT CG R+C+ C+ + +     KC  +   +I   ++   DN
Sbjct: 64  LESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVDN--EILLENQLFPDN 121

Query: 333 AVNREIGQLKVKCLFSACKYEGLLRDIGDHLDSCVHQLVSCPECNEELPKNDLKDHLEKN 512
              REI  L VKC    C  +  LR + DH   C   LV+CP+C     K  +  H+ ++
Sbjct: 122 FAKREILSLTVKCPNKGCLQKMELRHLEDHQVHCEFALVNCPQCQRPFQKCQVNTHIIED 181

Query: 513 CQMRLVNCKHCGEIMAYQTLDKSHLDPKNENICPKLEGFCPYKCDNKKI-VNLLNHRK-E 686
           C  R V+C +C   MAY+  +       ++  CP     C Y C    I   + NH   +
Sbjct: 182 CPRRQVSCVNCAVSMAYEEKE------IHDQSCPLANIICEY-CGTILIREQMPNHYDLD 234

Query: 687 CSKKPITCPFSVIG 728
           C   PI C FSV G
Sbjct: 235 CPTAPIPCTFSVFG 248
>sp|Q61382|TRAF4_MOUSE TNF receptor-associated factor 4 (Cysteine-rich motif associated to
           RING and Traf domains protein 1)
          Length = 470

 Score = 95.1 bits (235), Expect = 2e-19
 Identities = 55/196 (28%), Positives = 97/196 (49%), Gaps = 7/196 (3%)
 Frame = +3

Query: 150 FPFNISDNLKCIICTQLLLNALQTD-CGCRYCQICLDEYMGQGKKKCLTEGCG-DISRTI 323
           FP      L C +C + + ++++   CG RYC  CL E++ +G  KC  +    D ++  
Sbjct: 8   FPEKPKRRLLCPLCGKPMRDSVEVSTCGHRYCDNCLQEFLSEGVFKCPEDQLPLDYAKIY 67

Query: 324 SDNAVNREIGQLKVKCLFS--ACKYEGLLRDIGDHLDSCVHQLVSCP-ECNEELPKNDLK 494
            D  +  ++  L ++C+ S   C++ G LR +  HL++C   +V CP  C  +L + DL 
Sbjct: 68  PDPELEVQVLGLAIRCIHSEEGCRWSGPLRHLQGHLNTCSFNVVPCPNRCPAKLSRRDLP 127

Query: 495 DHLEKNCQMRLVNCKHCGEIMAYQTLDKSHLDPKNENICPKLEGFCPYKCDNKKIVNLL- 671
            HL+ +C  R + C+ CG   + +  +       +E +CP+   FC  KC  + +  LL 
Sbjct: 128 AHLQHDCPKRRLKCEFCGCDFSGEAYE------SHEGVCPQESVFCENKCGARMMRRLLA 181

Query: 672 -NHRKECSKKPITCPF 716
            +   EC K+   C +
Sbjct: 182 QHATSECPKRTQPCAY 197
>sp|O00463|TRAF5_HUMAN TNF receptor-associated factor 5 (RING finger protein 84)
          Length = 557

 Score = 90.9 bits (224), Expect = 4e-18
 Identities = 67/250 (26%), Positives = 107/250 (42%), Gaps = 13/250 (5%)
 Frame = +3

Query: 54  NKFLGLSYLQDRKMASLNTDLPKNIKRYRKKNFPFNISDNLKCIICTQLLLNALQTDCGC 233
           +K +   +++     S++ D   +I+      F   + +  KC  C  +L N  QT CG 
Sbjct: 7   HKGMPCGFIRQNSGNSISLDFEPSIEY----QFVERLEERYKCAFCHSVLHNPHQTGCGH 62

Query: 234 RYCQICLDEYMGQGKKKCLTEGCGDISRTI-------SDNAVNREIGQLKVKCLFS-ACK 389
           R+CQ C+        ++  T     + + +        DN   RE+  L V C  +  C 
Sbjct: 63  RFCQHCI-----LSLRELNTVPICPVDKEVIKSQEVFKDNCCKREVLNLYVYCSNAPGCN 117

Query: 390 YEGLLRDIGDHLDSCVHQLVSC--PECNEELPKNDLKDHLEKNCQMRLVNCKHCGEIMAY 563
            + +L    DHL  C+ Q V C   +C E + + DLK+HL  +CQ R   C +C + +  
Sbjct: 118 AKVILGRYQDHLQQCLFQPVQCSNEKCREPVLRKDLKEHLSASCQFRKEKCLYCKKDVVV 177

Query: 564 QTLDKSHLDPKNENICPKLEGFCPYKCDNKKIV---NLLNHRKECSKKPITCPFSVIGL* 734
                 +L    EN+CP+   FCP  C   KI+    +  H   C +    CPF   G  
Sbjct: 178 -----INLQNHEENLCPEYPVFCPNNC--AKIILKTEVDEHLAVCPEAEQDCPFKHYGCA 230

Query: 735 QSDDERKSEQ 764
            +D  R  +Q
Sbjct: 231 VTDKRRNLQQ 240
>sp|Q12933|TRAF2_HUMAN TNF receptor-associated factor 2 (Tumor necrosis factor type 2
           receptor-associated protein 3)
          Length = 501

 Score = 90.1 bits (222), Expect = 7e-18
 Identities = 58/208 (27%), Positives = 82/208 (39%), Gaps = 13/208 (6%)
 Frame = +3

Query: 180 CIICTQLLLNALQTDCGCRYCQICLDEYMGQGKKKCLT--------EGCG--DISRTISD 329
           C  C  +L    Q  CG RYC  CL   +  G + C          EG    + S    D
Sbjct: 34  CSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGISILESSSAFPD 93

Query: 330 NAVNREIGQLKVKCLFSACKYEGLLRDIGD-HLDSCVHQLVSCPECNEELPKNDLKDHLE 506
           NA  RE+  L   C    C ++G L++    H   C   L  CP C   +   + + HLE
Sbjct: 94  NAARREVESLPAVCPSDGCTWKGTLKEYESCHEGRCPLMLTECPACKGLVRLGEKERHLE 153

Query: 507 KNCQMRLVNCKHCGEIMAYQTLDKSHLDPKNENICPKLEGFCPYKCDNKKI--VNLLNHR 680
             C  R ++C+HC        +   H       +CPK    C   C  KKI      +H 
Sbjct: 154 HECPERSLSCRHCRAPCCGADVKAHH------EVCPKFPLTCD-GCGKKKIpreKFQDHV 206

Query: 681 KECSKKPITCPFSVIGL*QSDDERKSEQ 764
           K C K  + C F  IG  ++ +  K ++
Sbjct: 207 KTCGKCRVPCRFHAIGCLETVEGEKQQE 234
>sp|Q9BUZ4|TRAF4_HUMAN TNF receptor-associated factor 4 (Cysteine-rich domain associated
           with RING and Traf domains protein 1) (Malignant 62)
           (RING finger protein 83)
          Length = 470

 Score = 89.7 bits (221), Expect = 9e-18
 Identities = 51/188 (27%), Positives = 93/188 (49%), Gaps = 7/188 (3%)
 Frame = +3

Query: 174 LKCIICTQLLLNALQTD-CGCRYCQICLDEYMGQGKKKCLTEGCG-DISRTISDNAVNRE 347
           L C +C + +   +Q   CG R+C  CL E++ +G  KC  +    D ++   D  +  +
Sbjct: 16  LLCPLCGKPMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPEDQLPLDYAKIYPDPELEVQ 75

Query: 348 IGQLKVKCLFS--ACKYEGLLRDIGDHLDSCVHQLVSCP-ECNEELPKNDLKDHLEKNCQ 518
           +  L ++C+ S   C++ G LR +  HL++C   ++ CP  C  +L + DL  HL+ +C 
Sbjct: 76  VLGLPIRCIHSEEGCRWSGPLRHLQGHLNTCSFNVIPCPNRCPMKLSRRDLPAHLQHDCP 135

Query: 519 MRLVNCKHCGEIMAYQTLDKSHLDPKNENICPKLEGFCPYKCDNKKIVNLL--NHRKECS 692
            R + C+ CG   + +  +       +E +CP+   +C  KC  + +  LL  +   EC 
Sbjct: 136 KRRLKCEFCGCDFSGEAYE------SHEGMCPQESVYCENKCGARMMRRLLAQHATSECP 189

Query: 693 KKPITCPF 716
           K+   C +
Sbjct: 190 KRTQPCTY 197
>sp|P39429|TRAF2_MOUSE TNF receptor-associated factor 2
          Length = 501

 Score = 89.7 bits (221), Expect = 9e-18
 Identities = 55/196 (28%), Positives = 81/196 (41%), Gaps = 13/196 (6%)
 Frame = +3

Query: 180 CIICTQLLLNALQTDCGCRYCQICLDEYMGQGKKKCLT--------EGCG--DISRTISD 329
           C  C  +L    Q  CG RYC  CL   +  G + C          EG    + S    D
Sbjct: 34  CSACKNILRRPFQAQCGHRYCSFCLTSILSSGPQNCAACVYEGLYEEGISILESSSAFPD 93

Query: 330 NAVNREIGQLKVKCLFSACKYEGLLRDIGD-HLDSCVHQLVSCPECNEELPKNDLKDHLE 506
           NA  RE+  L   C    C ++G L++    H   C   L  CP C   +  ++ + H E
Sbjct: 94  NAARREVESLPAVCPNDGCTWKGTLKEYESCHEGLCPFLLTECPACKGLVRLSEKEHHTE 153

Query: 507 KNCQMRLVNCKHCGEIMAYQTLDKSHLDPKNENICPKLEGFCPYKCDNKKI--VNLLNHR 680
           + C  R ++C+HC    ++  L+  +       +CPK    C   C  KKI      +H 
Sbjct: 154 QECPKRSLSCQHCRAPCSHVDLEVHY------EVCPKFPLTCD-GCGKKKIpreTFQDHV 206

Query: 681 KECSKKPITCPFSVIG 728
           + CSK  + C F  +G
Sbjct: 207 RACSKCRVLCRFHTVG 222

 Score = 32.0 bits (71), Expect = 2.2
 Identities = 16/58 (27%), Positives = 29/58 (50%)
 Frame = +1

Query: 679 VRNALRNQSLVRFR*LGCNKVMTKENLNSHNNEESFQHSSLLMKEITTMKSDISELKQ 852
           VR   + + L RF  +GC++++  ENL  H  +   +H +LL+      ++    L Q
Sbjct: 206 VRACSKCRVLCRFHTVGCSEMVETENLQDHELQRLREHLALLLSSFLEAQASPGTLNQ 263
>sp|P70191|TRAF5_MOUSE TNF receptor-associated factor 5
          Length = 558

 Score = 80.9 bits (198), Expect = 4e-15
 Identities = 56/199 (28%), Positives = 77/199 (38%), Gaps = 6/199 (3%)
 Frame = +3

Query: 150 FPFNISDNLKCIICTQLLLNALQTDCGCRYCQICLDEYMGQGKKKCLTEGCGDI--SRTI 323
           F   + +  KC  C  +L N  QT CG R+CQ C+                  I      
Sbjct: 35  FVEQLEERYKCAFCHSVLHNPHQTGCGHRFCQQCIRSLRELNSVPICPVDKEVIKPQEVF 94

Query: 324 SDNAVNREIGQLKVKCLFS-ACKYEGLLRDIGDHLDSCVHQLVSCP--ECNEELPKNDLK 494
            DN   RE+  L V C  +  C    +L    DHL  C  Q V CP   C E + + D+K
Sbjct: 95  KDNCCKREVLNLHVYCKNAPGCNARIILGRFQDHLQHCSFQAVPCPNESCREAMLRKDVK 154

Query: 495 DHLEKNCQMRLVNCKHCGEIMAYQTLDKSHLDPKNENICPKLEGFCPYKC-DNKKIVNLL 671
           +HL   C+ R   C +C      + +  ++L    EN CP     CP +C        + 
Sbjct: 155 EHLSAYCRFREEKCLYC-----KRDIVVTNLQDHEENSCPAYPVSCPNRCVQTIPRARVN 209

Query: 672 NHRKECSKKPITCPFSVIG 728
            H   C +    CPF   G
Sbjct: 210 EHLTVCPEAEQDCPFKHYG 228
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 100,559,680
Number of Sequences: 369166
Number of extensions: 2192281
Number of successful extensions: 6201
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5708
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6132
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8438301375
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)