Planaria EST Database


DrC_02503

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_02503
         (863 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q9XVN3|IASPP_CAEEL  Apoptotic enhancer 1 protein (Inhibit...    80   6e-15
sp|Q96KQ4|ASPP1_HUMAN  Apoptosis stimulating of p53 protein ...    72   2e-12
sp|Q62415|ASPP1_MOUSE  Apoptosis stimulating of p53 protein ...    72   2e-12
sp|Q13625|ASPP2_HUMAN  Apoptosis stimulating of p53 protein ...    70   6e-12
sp|Q8CG79|ASPP2_MOUSE  Apoptosis stimulating of p53 protein ...    70   6e-12
sp|Q8WUF5|IASPP_HUMAN  RelA-associated inhibitor (Inhibitor ...    67   5e-11
sp|Q5I1X5|IASPP_MOUSE  RelA-associated inhibitor (Inhibitor ...    66   1e-10
sp|O14974|MYPT1_HUMAN  Protein phosphatase 1 regulatory subu...    52   2e-06
sp|Q9DBR7|MYPT1_MOUSE  Protein phosphatase 1 regulatory subu...    52   2e-06
sp|Q10728|MYPT1_RAT  Protein phosphatase 1 regulatory subuni...    52   2e-06
>sp|Q9XVN3|IASPP_CAEEL Apoptotic enhancer 1 protein (Inhibitor member of the ASPP family)
           (Protein iASPP) (Ce-iASPP)
          Length = 769

 Score = 80.5 bits (197), Expect = 6e-15
 Identities = 43/105 (40%), Positives = 65/105 (61%), Gaps = 2/105 (1%)
 Frame = +3

Query: 555 RAKDALNINPHHGI--LSVKPLDNSENHKVKKRKAIFDPHILLLDACLEPDFELVKELVP 728
           R+ D  N+     I   +VK +    N K+ K +  FDP  LLLDA LE + +LV+    
Sbjct: 515 RSDDGQNLEMEVAIERRTVKGILRRPNEKMNKGRIEFDPLALLLDAALEGELDLVRSSAS 574

Query: 729 KVPNISKKTIDGITALHNAVCSADPKLVLFLLQSGADVNASDADG 863
           K+ ++S+   +GITALHNA+C+   ++V FL+++ ADVNA D+DG
Sbjct: 575 KLTDVSQANDEGITALHNAICAGHYEIVRFLIENDADVNAQDSDG 619
>sp|Q96KQ4|ASPP1_HUMAN Apoptosis stimulating of p53 protein 1 (Protein phosphatase 1
            regulatory subunit 13B)
          Length = 1090

 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 39/86 (45%), Positives = 55/86 (63%)
 Frame = +3

Query: 606  KPLDNSENHKVKKRKAIFDPHILLLDACLEPDFELVKELVPKVPNISKKTIDGITALHNA 785
            KP      H ++ R   F+P  LLLDA LE +F+LV+ ++ +V + SK   +GIT LHNA
Sbjct: 872  KPNSERTGHGLRVR---FNPLALLLDASLEGEFDLVQRIIYEVEDPSKPNDEGITPLHNA 928

Query: 786  VCSADPKLVLFLLQSGADVNASDADG 863
            VC+    +V FLL  G +VNA+D+DG
Sbjct: 929  VCAGHHHIVKFLLDFGVNVNAADSDG 954
>sp|Q62415|ASPP1_MOUSE Apoptosis stimulating of p53 protein 1 (Protein phosphatase 1
            regulatory subunit 13B)
          Length = 1087

 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 39/86 (45%), Positives = 55/86 (63%)
 Frame = +3

Query: 606  KPLDNSENHKVKKRKAIFDPHILLLDACLEPDFELVKELVPKVPNISKKTIDGITALHNA 785
            KP      H ++ R   F+P  LLLDA LE +F+LV+ ++ +V + SK   +GIT LHNA
Sbjct: 869  KPNSERTGHGLRVR---FNPLALLLDASLEGEFDLVQRIIYEVEDPSKPNDEGITPLHNA 925

Query: 786  VCSADPKLVLFLLQSGADVNASDADG 863
            VC+    +V FLL  G +VNA+D+DG
Sbjct: 926  VCAGHHHIVKFLLDFGVNVNAADSDG 951
>sp|Q13625|ASPP2_HUMAN Apoptosis stimulating of p53 protein 2 (Tumor suppressor p53-binding
            protein 2) (p53-binding protein 2) (53BP2) (Bcl2-binding
            protein) (Bbp)
          Length = 1128

 Score = 70.5 bits (171), Expect = 6e-12
 Identities = 34/69 (49%), Positives = 51/69 (73%)
 Frame = +3

Query: 657  FDPHILLLDACLEPDFELVKELVPKVPNISKKTIDGITALHNAVCSADPKLVLFLLQSGA 836
            F+P  LLLD+ LE +F+LV+ ++ +V + S    +GITALHNAVC+   ++V FL+Q G 
Sbjct: 924  FNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGV 983

Query: 837  DVNASDADG 863
            +VNA+D+DG
Sbjct: 984  NVNAADSDG 992
>sp|Q8CG79|ASPP2_MOUSE Apoptosis stimulating of p53 protein 2 (Tumor suppressor p53-binding
            protein 2)
          Length = 1088

 Score = 70.5 bits (171), Expect = 6e-12
 Identities = 34/69 (49%), Positives = 51/69 (73%)
 Frame = +3

Query: 657  FDPHILLLDACLEPDFELVKELVPKVPNISKKTIDGITALHNAVCSADPKLVLFLLQSGA 836
            F+P  LLLD+ LE +F+LV+ ++ +V + S    +GITALHNAVC+   ++V FL+Q G 
Sbjct: 884  FNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGV 943

Query: 837  DVNASDADG 863
            +VNA+D+DG
Sbjct: 944  NVNAADSDG 952
>sp|Q8WUF5|IASPP_HUMAN RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein
           iASPP) (PPP1R13B-like protein) (NFkB-interacting protein
           1)
          Length = 828

 Score = 67.4 bits (163), Expect = 5e-11
 Identities = 33/75 (44%), Positives = 53/75 (70%)
 Frame = +3

Query: 639 KKRKAIFDPHILLLDACLEPDFELVKELVPKVPNISKKTIDGITALHNAVCSADPKLVLF 818
           K R+A  +P +LLLDA L  + E+V++ V ++ + S+   +GITALHNA+C A+  +V F
Sbjct: 619 KARRARLNPLVLLLDAALTGELEVVQQAVKEMNDPSQPNEEGITALHNAICGANYSIVDF 678

Query: 819 LLQSGADVNASDADG 863
           L+ +GA+VN+ D+ G
Sbjct: 679 LITAGANVNSPDSHG 693
>sp|Q5I1X5|IASPP_MOUSE RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein
           iASPP) (PPP1R13B-like protein) (NFkB-interacting protein
           1)
          Length = 824

 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 32/75 (42%), Positives = 53/75 (70%)
 Frame = +3

Query: 639 KKRKAIFDPHILLLDACLEPDFELVKELVPKVPNISKKTIDGITALHNAVCSADPKLVLF 818
           K R+A  +P +LLLDA L  + ++V++ V ++ + S+   +GITALHNA+C A+  +V F
Sbjct: 615 KARRARLNPLVLLLDAALTGELDVVQQAVKEMNDPSQPNEEGITALHNAICGANYPIVDF 674

Query: 819 LLQSGADVNASDADG 863
           L+ +GA+VN+ D+ G
Sbjct: 675 LIAAGANVNSPDSHG 689
>sp|O14974|MYPT1_HUMAN Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase
           targeting subunit 1) (Myosin phosphatase target subunit
           1) (Protein phosphatase myosin-binding subunit)
          Length = 1030

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 27/77 (35%), Positives = 45/77 (58%)
 Frame = +3

Query: 633 KVKKRKAIFDPHILLLDACLEPDFELVKELVPKVPNISKKTIDGITALHNAVCSADPKLV 812
           K +K K  FD   + L AC   D + V +L+ +  +I+   +DG+TALH A    +  +V
Sbjct: 30  KRQKTKVKFDDGAVFLAACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMV 89

Query: 813 LFLLQSGADVNASDADG 863
            FL+++GA++N  D +G
Sbjct: 90  KFLVENGANINQPDNEG 106

 Score = 30.8 bits (68), Expect = 5.1
 Identities = 15/34 (44%), Positives = 20/34 (58%)
 Frame = +3

Query: 762 GITALHNAVCSADPKLVLFLLQSGADVNASDADG 863
           G TALH A      +++  L+Q+G DVN  D DG
Sbjct: 199 GGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDG 232
>sp|Q9DBR7|MYPT1_MOUSE Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase
           targeting subunit 1) (Myosin phosphatase target subunit
           1)
          Length = 1004

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 27/77 (35%), Positives = 45/77 (58%)
 Frame = +3

Query: 633 KVKKRKAIFDPHILLLDACLEPDFELVKELVPKVPNISKKTIDGITALHNAVCSADPKLV 812
           K +K K  FD   + L AC   D + V +L+ +  +I+   +DG+TALH A    +  +V
Sbjct: 30  KRQKTKVKFDDGAVFLAACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMV 89

Query: 813 LFLLQSGADVNASDADG 863
            FL+++GA++N  D +G
Sbjct: 90  KFLVENGANINQPDNEG 106

 Score = 30.8 bits (68), Expect = 5.1
 Identities = 15/34 (44%), Positives = 20/34 (58%)
 Frame = +3

Query: 762 GITALHNAVCSADPKLVLFLLQSGADVNASDADG 863
           G TALH A      +++  L+Q+G DVN  D DG
Sbjct: 199 GGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDG 232
>sp|Q10728|MYPT1_RAT Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase
           targeting subunit 1) (Myosin phosphatase target subunit
           1) (Protein phosphatase myosin-binding subunit) (MBSP)
           (Serine/threonine protein phosphatase PP1 smooth muscle
           regulatory subunit M110) (Protein phosphatase subunit
           1M) (PP-1M)
          Length = 1032

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 27/77 (35%), Positives = 45/77 (58%)
 Frame = +3

Query: 633 KVKKRKAIFDPHILLLDACLEPDFELVKELVPKVPNISKKTIDGITALHNAVCSADPKLV 812
           K +K K  FD   + L AC   D + V +L+ +  +I+   +DG+TALH A    +  +V
Sbjct: 30  KRQKTKVKFDDGAVFLAACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMV 89

Query: 813 LFLLQSGADVNASDADG 863
            FL+++GA++N  D +G
Sbjct: 90  KFLVENGANINQPDNEG 106

 Score = 30.8 bits (68), Expect = 5.1
 Identities = 15/34 (44%), Positives = 20/34 (58%)
 Frame = +3

Query: 762 GITALHNAVCSADPKLVLFLLQSGADVNASDADG 863
           G TALH A      +++  L+Q+G DVN  D DG
Sbjct: 199 GGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDG 232
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 84,661,242
Number of Sequences: 369166
Number of extensions: 1560778
Number of successful extensions: 4592
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4182
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4586
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8582957970
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)