Planaria EST Database


DrC_02490

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_02490
         (488 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q13114|TRAF3_HUMAN  TNF receptor-associated factor 3 (CD4...    67   2e-11
sp|Q60803|TRAF3_MOUSE  TNF receptor-associated factor 3 (CD4...    67   2e-11
sp|P70191|TRAF5_MOUSE  TNF receptor-associated factor 5            66   5e-11
sp|Q61382|TRAF4_MOUSE  TNF receptor-associated factor 4 (Cys...    60   3e-09
sp|Q12933|TRAF2_HUMAN  TNF receptor-associated factor 2 (Tum...    59   8e-09
sp|Q9BUZ4|TRAF4_HUMAN  TNF receptor-associated factor 4 (Cys...    57   2e-08
sp|P39429|TRAF2_MOUSE  TNF receptor-associated factor 2            57   2e-08
sp|O00463|TRAF5_HUMAN  TNF receptor-associated factor 5 (RIN...    55   9e-08
sp|Q13077|TRAF1_HUMAN  TNF receptor-associated factor 1 (Eps...    54   1e-07
sp|P39428|TRAF1_MOUSE  TNF receptor-associated factor 1            54   2e-07
>sp|Q13114|TRAF3_HUMAN TNF receptor-associated factor 3 (CD40 receptor associated factor
           1) (CRAF1) (CD40 binding protein) (CD40BP) (LMP1
           associated protein) (LAP1) (CAP-1)
          Length = 568

 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 41/131 (31%), Positives = 70/131 (53%), Gaps = 2/131 (1%)
 Frame = +3

Query: 18  NVYSKPFYS--FGYKMRLRANLSRHQNGESTYLSVYFSLLEGENDDTLLWPMERRISIAL 191
           ++YS+PFY+  FGYKM  R  L+    G+ T+LS++F ++ GE D  L WP ++++++ L
Sbjct: 439 SLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLML 498

Query: 192 MDQRNNTIHTCKTYCVNTVAENFKEIFQKPAFRKLGEDYYYGSETLININSIMNNAKLYK 371
           MDQ ++  H    +  +  + +FK    KP     GE        +    +++ N    K
Sbjct: 499 MDQGSSRRHLGDAFKPDPNSSSFK----KPT----GEMNIASGCPVFVAQTVLENGTYIK 550

Query: 372 KDSIVIKCFVE 404
            D+I IK  V+
Sbjct: 551 DDTIFIKVIVD 561
>sp|Q60803|TRAF3_MOUSE TNF receptor-associated factor 3 (CD40 receptor associated factor
           1) (CRAF1) (TRAFAMN)
          Length = 567

 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 41/131 (31%), Positives = 70/131 (53%), Gaps = 2/131 (1%)
 Frame = +3

Query: 18  NVYSKPFYS--FGYKMRLRANLSRHQNGESTYLSVYFSLLEGENDDTLLWPMERRISIAL 191
           ++YS+PFY+  FGYKM  R  L+    G+ T+LS++F ++ GE D  L WP ++++++ L
Sbjct: 438 SLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLML 497

Query: 192 MDQRNNTIHTCKTYCVNTVAENFKEIFQKPAFRKLGEDYYYGSETLININSIMNNAKLYK 371
           MDQ ++  H    +  +  + +FK    KP     GE        +    +++ N    K
Sbjct: 498 MDQGSSRRHLGDAFKPDPNSSSFK----KPT----GEMNIASGCPVFVAQTVLENGTYIK 549

Query: 372 KDSIVIKCFVE 404
            D+I IK  V+
Sbjct: 550 DDTIFIKVIVD 560
>sp|P70191|TRAF5_MOUSE TNF receptor-associated factor 5
          Length = 558

 Score = 65.9 bits (159), Expect = 5e-11
 Identities = 40/133 (30%), Positives = 74/133 (55%), Gaps = 4/133 (3%)
 Frame = +3

Query: 18  NVYSKPFYSF--GYKMRLRANLSRHQNGESTYLSVYFSLLEGENDDTLLWPMERRISIAL 191
           +V+S+PFY+   GY++  RA L+   +G+ T+LS+YF ++ GE D  L WP  +R+++ L
Sbjct: 427 SVFSQPFYTSRCGYRLCARAYLNGDGSGKGTHLSLYFVVMRGEFDSLLQWPFRQRVTLML 486

Query: 192 MDQRNNTIHTCKTYCVNTVAENFKEIFQKPAFRKLGE-DYYYGSETLININSIMNNAKLY 368
           +DQ     H  +T+  +  + +FK        R  GE +   G    ++ +++ N+   Y
Sbjct: 487 LDQSGKKNHIVETFKADPNSSSFK--------RPDGEMNIASGCPRFVSHSTLENSKNTY 538

Query: 369 -KKDSIVIKCFVE 404
            K D++ +K  V+
Sbjct: 539 IKDDTLFLKVAVD 551
>sp|Q61382|TRAF4_MOUSE TNF receptor-associated factor 4 (Cysteine-rich motif associated to
           RING and Traf domains protein 1)
          Length = 470

 Score = 60.1 bits (144), Expect = 3e-09
 Identities = 30/91 (32%), Positives = 57/91 (62%), Gaps = 6/91 (6%)
 Frame = +3

Query: 12  NTNVYSKPFYS--FGYKMRLRANLSRHQNGESTYLSVYFSLLEGENDDTLLWPMERRISI 185
           N   +S  FY+  +GYK+++ A+L+ + +GE T+LS+Y  +L G  D+ L WP+ RR++ 
Sbjct: 329 NLECFSPAFYTHKYGYKLQVSASLNGNGSGEGTHLSIYIRVLPGAFDNLLEWPLARRVTF 388

Query: 186 ALMDQRNNTI----HTCKTYCVNTVAENFKE 266
           +L+DQ +  +    H  +T+  +   +NF++
Sbjct: 389 SLLDQSDPGLAKPQHVTETFHPDPNWKNFQK 419
>sp|Q12933|TRAF2_HUMAN TNF receptor-associated factor 2 (Tumor necrosis factor type 2
           receptor-associated protein 3)
          Length = 501

 Score = 58.5 bits (140), Expect = 8e-09
 Identities = 28/83 (33%), Positives = 50/83 (60%), Gaps = 2/83 (2%)
 Frame = +3

Query: 21  VYSKPFYS--FGYKMRLRANLSRHQNGESTYLSVYFSLLEGENDDTLLWPMERRISIALM 194
           ++S  FY+  +GYKM LR  L+    G  T+LS++F +++G ND  L WP  +++++ L+
Sbjct: 376 IFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLL 435

Query: 195 DQRNNTIHTCKTYCVNTVAENFK 263
           DQ NN  H    +  +  + +F+
Sbjct: 436 DQ-NNREHVIDAFRPDVTSSSFQ 457
>sp|Q9BUZ4|TRAF4_HUMAN TNF receptor-associated factor 4 (Cysteine-rich domain associated
           with RING and Traf domains protein 1) (Malignant 62)
           (RING finger protein 83)
          Length = 470

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 30/91 (32%), Positives = 55/91 (60%), Gaps = 6/91 (6%)
 Frame = +3

Query: 12  NTNVYSKPFYS--FGYKMRLRANLSRHQNGESTYLSVYFSLLEGENDDTLLWPMERRISI 185
           N   +S  FY+  +GYK+++ A L+ + +GE T+LS+Y  +L G  D+ L WP  RR++ 
Sbjct: 329 NLECFSPAFYTHKYGYKLQVSAFLNGNGSGEGTHLSLYIRVLPGAFDNLLEWPFARRVTF 388

Query: 186 ALMDQRNNTI----HTCKTYCVNTVAENFKE 266
           +L+DQ +  +    H  +T+  +   +NF++
Sbjct: 389 SLLDQSDPGLAKPQHVTETFHPDPNWKNFQK 419
>sp|P39429|TRAF2_MOUSE TNF receptor-associated factor 2
          Length = 501

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 27/83 (32%), Positives = 49/83 (59%), Gaps = 2/83 (2%)
 Frame = +3

Query: 21  VYSKPFYS--FGYKMRLRANLSRHQNGESTYLSVYFSLLEGENDDTLLWPMERRISIALM 194
           ++S  FY+  +GYKM LR  L+    G  T+LS++F +++G ND  L WP  +++++ L+
Sbjct: 376 IFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLL 435

Query: 195 DQRNNTIHTCKTYCVNTVAENFK 263
           D  NN  H    +  +  + +F+
Sbjct: 436 D-HNNREHVIDAFRPDVTSSSFQ 457
>sp|O00463|TRAF5_HUMAN TNF receptor-associated factor 5 (RING finger protein 84)
          Length = 557

 Score = 55.1 bits (131), Expect = 9e-08
 Identities = 37/134 (27%), Positives = 67/134 (50%), Gaps = 5/134 (3%)
 Frame = +3

Query: 18  NVYSKPFYSF--GYKMRLRANLSRHQNGESTYLSVYFSLLEGENDDTLLWPMERRISIAL 191
           +++S+ FY+   GY++  RA L+   +G  ++LS+YF ++ GE D  L WP  +R+++ L
Sbjct: 427 SIFSQSFYTSRCGYRLCARAYLNGDGSGRGSHLSLYFVVMRGEFDSLLQWPFRQRVTLML 486

Query: 192 MDQRNNTIHTCKTYCVNTVAENFKEIFQKPAFRKL-GEDYYYGSETLININSIMNNAK-- 362
           +DQ               + E FK      +F++  GE            +S++ NAK  
Sbjct: 487 LDQSGK----------KNIMETFKPDPNSSSFKRPDGEMNIASGCPRFVAHSVLENAKNA 536

Query: 363 LYKKDSIVIKCFVE 404
             K D++ +K  V+
Sbjct: 537 YIKDDTLFLKVAVD 550
>sp|Q13077|TRAF1_HUMAN TNF receptor-associated factor 1 (Epstein-Barr virus-induced
           protein 6)
          Length = 416

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 36/132 (27%), Positives = 67/132 (50%), Gaps = 3/132 (2%)
 Frame = +3

Query: 18  NVYSKPFYS--FGYKMRLRANLSRHQNGESTYLSVYFSLLEGENDDTLLWPMERRISIAL 191
           +++S  FY+  +GYK+ LR  L+    G+ T+LS++  ++ GE D  L WP   +++  L
Sbjct: 290 SLFSPAFYTAKYGYKLCLRLYLNGDGTGKRTHLSLFIVIMRGEYDALLPWPFRNKVTFML 349

Query: 192 MDQRNNTIHTCKTYCVNTVAENFKEIFQKPAFRKLGEDYYYGSETLININSIMNNAKLY- 368
           +DQ NN  H    +  +  + +    FQ+P   +   +   G      ++ + +    Y 
Sbjct: 350 LDQ-NNREHAIDAFRPDLSSAS----FQRP---QSETNVASGCPLFFPLSKLQSPKHAYV 401

Query: 369 KKDSIVIKCFVE 404
           K D++ +KC VE
Sbjct: 402 KDDTMFLKCIVE 413
>sp|P39428|TRAF1_MOUSE TNF receptor-associated factor 1
          Length = 409

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 35/132 (26%), Positives = 68/132 (51%), Gaps = 3/132 (2%)
 Frame = +3

Query: 18  NVYSKPFYS--FGYKMRLRANLSRHQNGESTYLSVYFSLLEGENDDTLLWPMERRISIAL 191
           +++S  FY+  +GYK+ LR  L+   +G+ T+LS++  ++ GE D  L WP   +++  L
Sbjct: 283 SLFSPAFYTAKYGYKLCLRLYLNGDGSGKKTHLSLFIVIMRGEYDALLPWPFRNKVTFML 342

Query: 192 MDQRNNTIHTCKTYCVNTVAENFKEIFQKPAFRKLGEDYYYGSETLININSIMNNAKLY- 368
           +DQ NN  H    +  +  + +    FQ+P   +   +   G      ++ + +    Y 
Sbjct: 343 LDQ-NNREHAIDAFRPDLSSAS----FQRP---QSETNVASGCPLFFPLSKLQSPKHAYV 394

Query: 369 KKDSIVIKCFVE 404
           K D++ +KC V+
Sbjct: 395 KDDTMFLKCIVD 406
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 53,818,411
Number of Sequences: 369166
Number of extensions: 1028733
Number of successful extensions: 2725
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2681
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2721
length of database: 68,354,980
effective HSP length: 102
effective length of database: 49,512,010
effective search space used: 2970720600
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)