Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_02479 (676 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q8INK6|PGPLB_DROME Peptidoglycan-recognition protein-LB ... 164 2e-40 sp|Q96PD5|PGRP2_HUMAN N-acetylmuramoyl-L-alanine amidase pr... 158 1e-38 sp|Q8VCS0|PGRP2_MOUSE N-acetylmuramoyl-L-alanine amidase pr... 154 3e-37 sp|Q866Y3|PGRP2_PIG N-acetylmuramoyl-L-alanine amidase prec... 150 4e-36 sp|Q70PY2|PGSB1_DROME Peptidoglycan-recognition protein-SB1... 132 8e-31 sp|Q70PU2|PGSC1_DROSI Peptidoglycan-recognition protein-SC1... 129 7e-30 sp|Q8SPP7|PGRP_BOVIN Peptidoglycan recognition protein prec... 128 1e-29 sp|O76537|PGRP_TRINI Peptidoglycan recognition protein prec... 128 1e-29 sp|Q70PU1|PGSC2_DROSI Peptidoglycan-recognition protein-SC2... 124 3e-28 sp|O75594|PGRP_HUMAN Peptidoglycan recognition protein prec... 123 4e-28
>sp|Q8INK6|PGPLB_DROME Peptidoglycan-recognition protein-LB precursor Length = 232 Score = 164 bits (415), Expect = 2e-40 Identities = 74/166 (44%), Positives = 103/166 (62%) Frame = +1 Query: 133 QFVSREEWGARPPKHIAILPAIPKYVFIHHTFTPAACYDLINCSEAMRSIQKFHMDVRGW 312 + +SR +WGAR PK + YV IHH++ PA CY +C ++MR +Q FH RGW Sbjct: 31 RLLSRSDWGARLPKSVEHFQGPAPYVIIHHSYMPAVCYSTPDCMKSMRDMQDFHQLERGW 90 Query: 313 DDIGYSFAIGGDGRVYVGRGWDRVGAHTLGYNTVGLGFVVIGDYRFHIPNEAAIDALRKS 492 +DIGYSF IGGDG +Y GRG++ +GAH YN +G V+IGD+R +P + +DA + Sbjct: 91 NDIGYSFGIGGDGMIYTGRGFNVIGAHAPKYNDKSVGIVLIGDWRTELPPKQMLDAAKNL 150 Query: 493 ISMGRRLNKIERNFTLKGHRDVRPTECPGEAFYDIIQTWPHYSRQN 630 I+ G I+ + L GHR VR TECPG + I +WPH++ N Sbjct: 151 IAFGVFKGYIDPAYKLLGHRQVRDTECPGGRLFAEISSWPHFTHIN 196
>sp|Q96PD5|PGRP2_HUMAN N-acetylmuramoyl-L-alanine amidase precursor (Peptidoglycan recognition protein long) (PGRP-L) (Peptidoglycan recognition protein 2) Length = 576 Score = 158 bits (399), Expect = 1e-38 Identities = 71/162 (43%), Positives = 106/162 (65%), Gaps = 3/162 (1%) Frame = +1 Query: 145 REEWGARPPKHIAILPAIPK-YVFIHHTFTPAA-CYDLINCSEAMRSIQKFHMDVRGWDD 318 R WGA P + L +P ++++HHT+ PA C D C+ MRS+Q++H D +GW D Sbjct: 385 RCRWGAAPYRGRPKLLQLPLGFLYVHHTYVPAPPCTDFTRCAANMRSMQRYHQDTQGWGD 444 Query: 319 IGYSFAIGGDGRVYVGRGWDRVGAHTLGYNTVGLGFVVIGDYRFHIPNEAAIDALRKSI- 495 IGYSF +G DG VY GRGW VGAHTLG+N+ G G ++G+Y +P EAA+ +R ++ Sbjct: 445 IGYSFVVGSDGYVYEGRGWHWVGAHTLGHNSRGFGVAIVGNYTAALPTEAALRTVRDTLP 504 Query: 496 SMGRRLNKIERNFTLKGHRDVRPTECPGEAFYDIIQTWPHYS 621 S R + ++ L GHR + T+CPG+A +D+++TWPH++ Sbjct: 505 SCAVRAGLLRPDYALLGHRQLVRTDCPGDALFDLLRTWPHFT 546
>sp|Q8VCS0|PGRP2_MOUSE N-acetylmuramoyl-L-alanine amidase precursor (Peptidoglycan recognition protein long) (PGRP-L) (Peptidoglycan recognition protein 2) (TagL) Length = 530 Score = 154 bits (388), Expect = 3e-37 Identities = 72/162 (44%), Positives = 104/162 (64%), Gaps = 3/162 (1%) Frame = +1 Query: 145 REEWGARPPK-HIAILPAIPKYVFIHHTFTPAA-CYDLINCSEAMRSIQKFHMDVRGWDD 318 R WGA P + H L ++++HHT+ PA C +C+ MRS+Q+FH DVR WDD Sbjct: 365 RCRWGAAPYRGHPTPLRLPLGFLYVHHTYVPAPPCTTFQSCAADMRSMQRFHQDVRKWDD 424 Query: 319 IGYSFAIGGDGRVYVGRGWDRVGAHTLGYNTVGLGFVVIGDYRFHIPNEAAIDALRKSI- 495 IGYSF +G DG +Y GRGW VGAHT GYN+ G G +G+Y +PNEAA++ +R ++ Sbjct: 425 IGYSFVVGSDGYLYQGRGWHWVGAHTRGYNSRGFGVAFVGNYTGSLPNEAALNTVRDALP 484 Query: 496 SMGRRLNKIERNFTLKGHRDVRPTECPGEAFYDIIQTWPHYS 621 S R + ++ L GHR + T CPG A +++++TWPH++ Sbjct: 485 SCAIRAGLLRPDYKLLGHRQLVLTHCPGNALFNLLRTWPHFT 526
>sp|Q866Y3|PGRP2_PIG N-acetylmuramoyl-L-alanine amidase precursor (Peptidoglycan recognition protein long) (PGRP-L) (Peptidoglycan recognition protein 2) Length = 598 Score = 150 bits (378), Expect = 4e-36 Identities = 70/162 (43%), Positives = 105/162 (64%), Gaps = 3/162 (1%) Frame = +1 Query: 145 REEWGARPPKHIAILPAIPK-YVFIHHTFTPAA-CYDLINCSEAMRSIQKFHMDVRGWDD 318 R WGA P + +P +++IHHT+ PA C D C+ MRS+Q+FH+D +GWDD Sbjct: 407 RCRWGAAPYRGSPKPLKLPLGFLYIHHTYVPARPCTDFALCAANMRSMQRFHLDTQGWDD 466 Query: 319 IGYSFAIGGDGRVYVGRGWDRVGAHTLGYNTVGLGFVVIGDYRFHIPNEAAIDALRKSI- 495 IGYSF +G DG VY GRGW VGAHT +N+ G G +IG+Y +P+EAA+ A+R + Sbjct: 467 IGYSFVVGSDGYVYEGRGWHWVGAHTRDHNSRGFGVALIGNYTAELPSEAALRAVRDELP 526 Query: 496 SMGRRLNKIERNFTLKGHRDVRPTECPGEAFYDIIQTWPHYS 621 R ++ ++ L GHR + T+CPG+A +++++TWP ++ Sbjct: 527 HCAVRAGLLQPDYALLGHRQLVRTDCPGDALFNMLRTWPRFN 568
>sp|Q70PY2|PGSB1_DROME Peptidoglycan-recognition protein-SB1 precursor Length = 190 Score = 132 bits (332), Expect = 8e-31 Identities = 62/170 (36%), Positives = 95/170 (55%) Frame = +1 Query: 121 SNAIQFVSREEWGARPPKHIAILPAIPKYVFIHHTFTPAACYDLINCSEAMRSIQKFHMD 300 +NA+Q R WGA + + + YV IHH+ P C C +++IQ H Sbjct: 22 ANALQIEPRSSWGAVSARSPSRISGAVDYVIIHHSDNPNGCSTSEQCKRMIKNIQSDHKG 81 Query: 301 VRGWDDIGYSFAIGGDGRVYVGRGWDRVGAHTLGYNTVGLGFVVIGDYRFHIPNEAAIDA 480 R + DIGY+F + GDG+VY GRG+ G+H+ YN +G V IG++ P+ + Sbjct: 82 RRNFSDIGYNFIVAGDGKVYEGRGFGLQGSHSPNYNRKSIGIVFIGNFERSAPSAQMLQN 141 Query: 481 LRKSISMGRRLNKIERNFTLKGHRDVRPTECPGEAFYDIIQTWPHYSRQN 630 + I + ++ ++ N+TL GHR + T CPG+A Y+ I+TWPH+ RQN Sbjct: 142 AKDLIELAKQRGYLKDNYTLFGHRQTKATSCPGDALYNEIKTWPHW-RQN 190
>sp|Q70PU2|PGSC1_DROSI Peptidoglycan-recognition protein-SC1a/b precursor Length = 185 Score = 129 bits (324), Expect = 7e-30 Identities = 61/167 (36%), Positives = 89/167 (53%) Frame = +1 Query: 121 SNAIQFVSREEWGARPPKHIAILPAIPKYVFIHHTFTPAACYDLINCSEAMRSIQKFHMD 300 + + VS+ EWG R K L Y IHHT + C C+ ++S+Q +HMD Sbjct: 19 AQGVYVVSKAEWGGRGAKWTVALGNYLSYAIIHHT-AGSYCETRAQCNAVLQSVQAYHMD 77 Query: 301 VRGWDDIGYSFAIGGDGRVYVGRGWDRVGAHTLGYNTVGLGFVVIGDYRFHIPNEAAIDA 480 GW DIGY+F IGGDG VY GRGW+ +GAH +N +G +G+Y + I A Sbjct: 78 SLGWPDIGYNFLIGGDGNVYEGRGWNNMGAHAAEWNPYSIGISFLGNYNWDTLEPNMISA 137 Query: 481 LRKSISMGRRLNKIERNFTLKGHRDVRPTECPGEAFYDIIQTWPHYS 621 ++ ++ ++ + L GHR V TECPG ++ I+ W H+S Sbjct: 138 AQQLLNDAVNRGQLSSGYILYGHRQVSATECPGTHIWNEIRGWSHWS 184
>sp|Q8SPP7|PGRP_BOVIN Peptidoglycan recognition protein precursor (Peptidoglycan recognition protein short) (PGRP-S) (Oligosaccharide-binding protein) (OBP) Length = 190 Score = 128 bits (322), Expect = 1e-29 Identities = 63/163 (38%), Positives = 94/163 (57%), Gaps = 1/163 (0%) Frame = +1 Query: 139 VSREEWGARPPKHIAILPAIPKYVFIHHTFTPAACYDLINCSEAMRSIQKFHMDVRGWDD 318 VSR +WGA K L +YV + HT + C +C +++Q +H+ RGW D Sbjct: 28 VSRGKWGALASKCSQRLRQPVRYVVVSHT-AGSVCNTPASCQRQAQNVQYYHVRERGWCD 86 Query: 319 IGYSFAIGGDGRVYVGRGWDRVGAHT-LGYNTVGLGFVVIGDYRFHIPNEAAIDALRKSI 495 +GY+F IG DG VY GRGW+ +GAH+ +N + +G +G+Y +P +A+ A + + Sbjct: 87 VGYNFLIGEDGLVYEGRGWNTLGAHSGPTWNPIAIGISFMGNYMHRVPPASALRAAQSLL 146 Query: 496 SMGRRLNKIERNFTLKGHRDVRPTECPGEAFYDIIQTWPHYSR 624 + G + N+ +KGHRDV+ T PG+ Y IIQ WPHY R Sbjct: 147 ACGAARGYLTPNYEVKGHRDVQQTLSPGDELYKIIQQWPHYRR 189
>sp|O76537|PGRP_TRINI Peptidoglycan recognition protein precursor Length = 182 Score = 128 bits (322), Expect = 1e-29 Identities = 63/160 (39%), Positives = 90/160 (56%) Frame = +1 Query: 139 VSREEWGARPPKHIAILPAIPKYVFIHHTFTPAACYDLINCSEAMRSIQKFHMDVRGWDD 318 V+++EW P H+ L + V I HT T + C C++ +R+IQ +HMD + D Sbjct: 21 VTKDEWDGLTPIHVEYLARPVELVIIQHTVT-STCNTDAACAQIVRNIQSYHMDNLNYWD 79 Query: 319 IGYSFAIGGDGRVYVGRGWDRVGAHTLGYNTVGLGFVVIGDYRFHIPNEAAIDALRKSIS 498 IG SF IGG+G+VY G GW VGAHT GYN +G IG+Y P + ++DALR + Sbjct: 80 IGSSFIIGGNGKVYEGAGWLHVGAHTYGYNRKSIGITFIGNYNNDKPTQKSLDALRALLR 139 Query: 499 MGRRLNKIERNFTLKGHRDVRPTECPGEAFYDIIQTWPHY 618 G + N+ + GHR + TE PG Y+ I+ W H+ Sbjct: 140 CGVERGHLTANYHIVGHRQLISTESPGRKLYNEIRRWDHF 179
>sp|Q70PU1|PGSC2_DROSI Peptidoglycan-recognition protein-SC2 precursor Length = 184 Score = 124 bits (310), Expect = 3e-28 Identities = 62/163 (38%), Positives = 87/163 (53%) Frame = +1 Query: 130 IQFVSREEWGARPPKHIAILPAIPKYVFIHHTFTPAACYDLINCSEAMRSIQKFHMDVRG 309 + VS+ EWG R L + Y IHHT C C +++IQ +HMD G Sbjct: 21 VTIVSKSEWGGRSATSKTSLASYLSYAVIHHT-AGNYCSTKAACITQLKNIQAYHMDSLG 79 Query: 310 WDDIGYSFAIGGDGRVYVGRGWDRVGAHTLGYNTVGLGFVVIGDYRFHIPNEAAIDALRK 489 W DIGY+F IGGDG VY GRGW+ +GAH +N+ +G +G+Y + A I A + Sbjct: 80 WADIGYNFLIGGDGNVYEGRGWNVMGAHATNWNSKSIGISFLGNYNTNTLTSAQITAAKG 139 Query: 490 SISMGRRLNKIERNFTLKGHRDVRPTECPGEAFYDIIQTWPHY 618 +S +I + L GHR V TECPG ++ I+TW ++ Sbjct: 140 LLSDAVSRGQIVSGYILYGHRQVGSTECPGTNIWNEIRTWSNW 182
>sp|O75594|PGRP_HUMAN Peptidoglycan recognition protein precursor (PGRP-S) Length = 196 Score = 123 bits (309), Expect = 4e-28 Identities = 62/161 (38%), Positives = 89/161 (55%), Gaps = 1/161 (0%) Frame = +1 Query: 139 VSREEWGARPPKHIAILPAIPKYVFIHHTFTPAACYDLINCSEAMRSIQKFHMDVRGWDD 318 V R EW A + L +YV + HT ++C +C + R++Q +HM GW D Sbjct: 34 VPRNEWKALASECAQHLSLPLRYVVVSHT-AGSSCNTPASCQQQARNVQHYHMKTLGWCD 92 Query: 319 IGYSFAIGGDGRVYVGRGWDRVGAHTLG-YNTVGLGFVVIGDYRFHIPNEAAIDALRKSI 495 +GY+F IG DG VY GRGW+ GAH+ +N + +G +G+Y +P AI A + + Sbjct: 93 VGYNFLIGEDGLVYEGRGWNFTGAHSGHLWNPMSIGISFMGNYMDRVPTPQAIRAAQGLL 152 Query: 496 SMGRRLNKIERNFTLKGHRDVRPTECPGEAFYDIIQTWPHY 618 + G + N+ LKGHRDV+ T PG Y +IQ WPHY Sbjct: 153 ACGVAQGALRSNYVLKGHRDVQRTLSPGNQLYHLIQNWPHY 193
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 70,415,484 Number of Sequences: 369166 Number of extensions: 1448793 Number of successful extensions: 3733 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 3619 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3709 length of database: 68,354,980 effective HSP length: 107 effective length of database: 48,588,335 effective search space used: 5684835195 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)