Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_02445 (687 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q9BV86|CI032_HUMAN Protein C9orf32 180 4e-45 sp|Q5BJX0|CI032_RAT Protein C9orf32 homolog 179 6e-45 sp|Q8R2U4|CI032_MOUSE Protein C9orf32 homolog 178 1e-44 sp|P38340|YB9H_YEAST Protein YBR261C 134 2e-31 sp|O13748|YDRE_SCHPO Hypothetical protein C16E8.14c in chro... 128 2e-29 sp|Q98MF0|PYRG_RHILO CTP synthase (UTP--ammonia ligase) (CT... 33 0.54 sp|Q8TU79|SYA_METAC Alanyl-tRNA synthetase (Alanine--tRNA l... 31 2.7 sp|Q98KB1|MURD_RHILO UDP-N-acetylmuramoylalanine--D-glutama... 31 2.7 sp|Q92QA0|PYRG_RHIME CTP synthase (UTP--ammonia ligase) (CT... 30 4.6 sp|Q58055|Y638_METJA Hypothetical protein MJ0638 30 4.6
>sp|Q9BV86|CI032_HUMAN Protein C9orf32 Length = 223 Score = 180 bits (456), Expect = 4e-45 Identities = 92/209 (44%), Positives = 127/209 (60%), Gaps = 1/209 (0%) Frame = +1 Query: 4 RKYWKEVSPTVNGMLGGFEIVSDGDIKTSTXXXXXXXXXGFLTKSTGKALDCGSGIGRVT 183 + YWK++ PTV+GMLGG+ +S DI +S G T ALDCG+GIGR+T Sbjct: 17 KTYWKQIPPTVDGMLGGYGHISSIDINSSRKFLQRFLREGPNKTGTSCALDCGAGIGRIT 76 Query: 184 KNLLMPIFPKVDMVEVTKHFLDESYKYIGETSQSI-NRICCSLQNFTPNQNDYDLIWCQW 360 K LL+P+F +VDMV++T+ FL ++ Y+GE + + N CC LQ+FTP + YD+IW QW Sbjct: 77 KRLLLPLFREVDMVDITEDFLVQAKTYLGEEGKRVRNYFCCGLQDFTPEPDSYDVIWIQW 136 Query: 361 VTGHLTDQALVEFLERCITGLHSKNSLIVIKENVVKGNXXXXXXXXXXXTRPISLLKRLF 540 V GHLTDQ L EFL RC G N +IVIK+N+ + R + +++R+ Sbjct: 137 VIGHLTDQHLAEFLRRC-KGSLRPNGIIVIKDNMAQ-EGVILDDVDSSVCRDLDVVRRII 194 Query: 541 VQANLELIKEERQTEFPKELYPVWMFVLR 627 A L L+ EERQ P E+Y V+ F LR Sbjct: 195 CSAGLSLLAEERQENLPDEIYHVYSFALR 223
>sp|Q5BJX0|CI032_RAT Protein C9orf32 homolog Length = 223 Score = 179 bits (454), Expect = 6e-45 Identities = 92/209 (44%), Positives = 128/209 (61%), Gaps = 1/209 (0%) Frame = +1 Query: 4 RKYWKEVSPTVNGMLGGFEIVSDGDIKTSTXXXXXXXXXGFLTKSTGKALDCGSGIGRVT 183 + YWK++ PTV+GMLGG+ +S+ D+ +S G T ALDCG+GIGR+T Sbjct: 17 KTYWKQIPPTVDGMLGGYGHISNIDLNSSRKFLQRFLREGPNKTGTSCALDCGAGIGRIT 76 Query: 184 KNLLMPIFPKVDMVEVTKHFLDESYKYIGETSQSI-NRICCSLQNFTPNQNDYDLIWCQW 360 K LL+P+F VDMV+VT+ FL ++ Y+GE + + N CC LQ+F+P + YD+IW QW Sbjct: 77 KRLLLPLFRVVDMVDVTEDFLAKAKTYLGEEGKRVRNYFCCGLQDFSPEPSSYDVIWIQW 136 Query: 361 VTGHLTDQALVEFLERCITGLHSKNSLIVIKENVVKGNXXXXXXXXXXXTRPISLLKRLF 540 V GHLTDQ L EFL RC GL N +IVIK+N+ + R + +++R+ Sbjct: 137 VIGHLTDQHLAEFLRRCRRGLR-PNGIIVIKDNMAQ-EGVILDDVDSSVCRDLEVVRRII 194 Query: 541 VQANLELIKEERQTEFPKELYPVWMFVLR 627 A L L+ EERQ P E+Y V+ F LR Sbjct: 195 RSAGLSLLAEERQENLPDEIYHVYSFALR 223
>sp|Q8R2U4|CI032_MOUSE Protein C9orf32 homolog Length = 223 Score = 178 bits (452), Expect = 1e-44 Identities = 92/209 (44%), Positives = 127/209 (60%), Gaps = 1/209 (0%) Frame = +1 Query: 4 RKYWKEVSPTVNGMLGGFEIVSDGDIKTSTXXXXXXXXXGFLTKSTGKALDCGSGIGRVT 183 + YWK++ PTV+GMLGG+ +S+ D+ +S G T ALDCG+GIGR+T Sbjct: 17 KTYWKQIPPTVDGMLGGYGHISNIDLNSSRKFLQRFLREGPNKTGTSCALDCGAGIGRIT 76 Query: 184 KNLLMPIFPKVDMVEVTKHFLDESYKYIGETSQSI-NRICCSLQNFTPNQNDYDLIWCQW 360 K LL+P+F VDMV+VT+ FL ++ Y+GE + + N CC LQ+F+P YD+IW QW Sbjct: 77 KRLLLPLFRVVDMVDVTEDFLAKAKTYLGEEGKRVRNYFCCGLQDFSPEPGSYDVIWIQW 136 Query: 361 VTGHLTDQALVEFLERCITGLHSKNSLIVIKENVVKGNXXXXXXXXXXXTRPISLLKRLF 540 V GHLTDQ L EFL RC GL N +IVIK+N+ + R + +++R+ Sbjct: 137 VIGHLTDQHLAEFLRRCKRGLR-PNGIIVIKDNMAQ-EGVILDDVDSSVCRDLEVVRRII 194 Query: 541 VQANLELIKEERQTEFPKELYPVWMFVLR 627 A L L+ EERQ P E+Y V+ F LR Sbjct: 195 RTAGLSLLAEERQENLPDEIYHVYSFALR 223
>sp|P38340|YB9H_YEAST Protein YBR261C Length = 232 Score = 134 bits (337), Expect = 2e-31 Identities = 81/217 (37%), Positives = 118/217 (54%), Gaps = 7/217 (3%) Frame = +1 Query: 10 YWKEVSPTVNGMLGGF---EIVSDGDIKTSTXXXXXXXXXGFLTKSTGK-ALDCGSGIGR 177 YW +V TV+G+LGG+ +V D+ S ++ K A+D G+GIGR Sbjct: 17 YWTDVDATVDGVLGGYGEGTVVPTMDVLGSNNFLRKLKSRMLPQENNVKYAVDIGAGIGR 76 Query: 178 VTKNLLMPIFPKVDMVEVTKHFLDESYKYIGETSQS--INRIC-CSLQNFTPNQNDYDLI 348 V+K +L K+D+VE K F+++ + + E I +I +Q++TP+ Y LI Sbjct: 77 VSKTMLHKHAAKIDLVEPVKPFIEQMHVELAELKDKGQIGQIYEVGMQDWTPDAGKYWLI 136 Query: 349 WCQWVTGHLTDQALVEFLERCITGLHSKNSLIVIKENVVKGNXXXXXXXXXXXTRPISLL 528 WCQW GHL D LV FL+RCI GL N IV+KEN + TR + Sbjct: 137 WCQWCVGHLPDAELVAFLKRCIVGL-QPNGTIVVKENNTPTDTDDFDETDSSVTRSDAKF 195 Query: 529 KRLFVQANLELIKEERQTEFPKELYPVWMFVLRPISN 639 +++F +A L+LI ERQ P+ELYPV M+ L+P+ N Sbjct: 196 RQIFEEAGLKLIASERQRGLpreLYPVRMYALKPMPN 232
>sp|O13748|YDRE_SCHPO Hypothetical protein C16E8.14c in chromosome I Length = 219 Score = 128 bits (321), Expect = 2e-29 Identities = 81/213 (38%), Positives = 111/213 (52%), Gaps = 3/213 (1%) Frame = +1 Query: 10 YWKEVSPTVNGMLGGF---EIVSDGDIKTSTXXXXXXXXXGFLTKSTGKALDCGSGIGRV 180 YW V PTV+GMLGG I + + T G + A DCG+GIGRV Sbjct: 13 YWNGVQPTVDGMLGGLGTGRIPQTDVVGSRTFLNRLNYRIGKIENLV--AADCGAGIGRV 70 Query: 181 TKNLLMPIFPKVDMVEVTKHFLDESYKYIGETSQSINRICCSLQNFTPNQNDYDLIWCQW 360 T+N+L+ I VD+VE ++F+ + K + S + LQN+TP +N Y LIW QW Sbjct: 71 TENVLLKIASHVDLVEPVENFISTAKKQLATKPCSFINV--GLQNWTPEKNRYGLIWNQW 128 Query: 361 VTGHLTDQALVEFLERCITGLHSKNSLIVIKENVVKGNXXXXXXXXXXXTRPISLLKRLF 540 HLTD+ L+ +L RC + K +I +KEN V TR LK LF Sbjct: 129 CLSHLTDEDLIAYLSRCCEAIQEK-GVICVKEN-VSSFEDTFDPIDSSVTRCEQSLKSLF 186 Query: 541 VQANLELIKEERQTEFPKELYPVWMFVLRPISN 639 +ANL ++ E Q FP+EL+PV M+ L P S+ Sbjct: 187 KKANLVVVAETLQHGFPEELFPVKMYALVPHSS 219
>sp|Q98MF0|PYRG_RHILO CTP synthase (UTP--ammonia ligase) (CTP synthetase) Length = 542 Score = 33.5 bits (75), Expect = 0.54 Identities = 31/133 (23%), Positives = 54/133 (40%), Gaps = 3/133 (2%) Frame = +1 Query: 16 KEVSPTVNGMLGGFEIVSDGDIKTSTXXXXXXXXXGFLTKSTGKALDCGSGI--GRVTKN 189 K++ P +N G G++ + G + TG++ + I GR+ KN Sbjct: 38 KKLDPYLNVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFTGRSANQQDNITTGRIYKN 97 Query: 190 LLMPIFPKVDMVEVTKHFLDESYKYIGETSQSINRICCSLQNFTPNQN-DYDLIWCQWVT 366 ++ + Y+G T Q I + ++NF N N DYD + C+ + Sbjct: 98 IIER---------------ERRGDYLGATVQVIPHVTDEIKNFVLNGNDDYDFVLCE-IG 141 Query: 367 GHLTDQALVEFLE 405 G + D + FLE Sbjct: 142 GTVGDIEAMPFLE 154
>sp|Q8TU79|SYA_METAC Alanyl-tRNA synthetase (Alanine--tRNA ligase) (AlaRS) Length = 925 Score = 31.2 bits (69), Expect = 2.7 Identities = 24/76 (31%), Positives = 38/76 (50%), Gaps = 1/76 (1%) Frame = -2 Query: 254 DSSKKCLVTSTMSTLGKIGISKFLVTRPIPDPQSRALPVDFVRNPLLIKFNNKFVDVLIS 75 D + C T +ST G IG K L T I D R V+F ++ K +L+ Sbjct: 709 DDVEACGGTHCLST-GVIGPIKILKTERIQDGVER---VEFAAGIAAVRAMQKMESLLVD 764 Query: 74 PSETISKPP-NIPLTV 30 ++T+S PP ++P++V Sbjct: 765 SAKTLSVPPEHLPVSV 780
>sp|Q98KB1|MURD_RHILO UDP-N-acetylmuramoylalanine--D-glutamate ligase (UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase) (D-glutamic acid-adding enzyme) Length = 466 Score = 31.2 bits (69), Expect = 2.7 Identities = 30/111 (27%), Positives = 44/111 (39%) Frame = +1 Query: 127 LTKSTGKALDCGSGIGRVTKNLLMPIFPKVDMVEVTKHFLDESYKYIGETSQSINRICCS 306 + KS G+ G IGR L D + +HF+ E Y + + SIN Sbjct: 135 ILKSAGRDTQMGGNIGRAVMTL--------DPPKPDRHFVVECSSYQIDLAPSINPTAGI 186 Query: 307 LQNFTPNQNDYDLIWCQWVTGHLTDQALVEFLERCITGLHSKNSLIVIKEN 459 L N TP+ D H T Q ER + G S+ ++I I ++ Sbjct: 187 LLNLTPDHLD----------RHGTMQHYASIKERLVAG--SETAIIGIDDS 225
>sp|Q92QA0|PYRG_RHIME CTP synthase (UTP--ammonia ligase) (CTP synthetase) Length = 542 Score = 30.4 bits (67), Expect = 4.6 Identities = 18/62 (29%), Positives = 33/62 (53%), Gaps = 3/62 (4%) Frame = +1 Query: 229 VTKHFLDESYK--YIGETSQSINRICCSLQNF-TPNQNDYDLIWCQWVTGHLTDQALVEF 399 + K+ +D+ + Y+G T Q I + ++NF T DYD + C+ + G + D + F Sbjct: 94 IYKNIIDKERRGDYLGATVQVIPHVTNEIKNFVTEGNEDYDFVICE-IGGTVGDIEAMPF 152 Query: 400 LE 405 +E Sbjct: 153 ME 154
>sp|Q58055|Y638_METJA Hypothetical protein MJ0638 Length = 225 Score = 30.4 bits (67), Expect = 4.6 Identities = 30/122 (24%), Positives = 47/122 (38%), Gaps = 7/122 (5%) Frame = +1 Query: 124 FLTKSTGKALDCGSGIGRVTKNLLMPIFPKVDMVEVTKHF----LDESYKYIGETSQSIN 291 F K LDCG G G +TK F LD S + Sbjct: 42 FENKKDFLVLDCGCGFGA--------------FYNLTKDFNTIYLDISLNLLKRFKLKER 87 Query: 292 RICCSLQNFTPNQNDYDLIWCQWVTGHLTDQALVEFLERCITGLHSKNSLIVI---KENV 462 +IC ++ + N +DL+ C V H+ + + R L +K LIV+ K+++ Sbjct: 88 KICANILHLPFKDNTFDLVLCINVLEHVNYLKALNEIRRI---LKNKGKLIVVVVNKDSL 144 Query: 463 VK 468 +K Sbjct: 145 IK 146
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 70,916,528 Number of Sequences: 369166 Number of extensions: 1283926 Number of successful extensions: 3223 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 3136 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3210 length of database: 68,354,980 effective HSP length: 107 effective length of database: 48,588,335 effective search space used: 5879188535 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)