Planaria EST Database


DrC_02411

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_02411
         (808 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q9H4M9|EHD1_HUMAN  EH-domain containing protein 1 (Testil...   236   4e-62
sp|Q9WVK4|EHD1_MOUSE  EH-domain containing protein 1 (mPAST1)     234   3e-61
sp|Q9NZN3|EHD3_HUMAN  EH-domain containing protein 3              230   4e-60
sp|Q9QXY6|EHD3_MOUSE  EH-domain containing protein 3              229   7e-60
sp|Q9H223|EHD4_HUMAN  EH-domain containing protein 4 (Hepato...   213   6e-55
sp|Q9EQP2|EHD4_MOUSE  EH-domain containing protein 4 (mPAST2)     206   6e-53
sp|Q9NZN4|EHD2_HUMAN  EH-domain containing protein 2              206   8e-53
sp|Q60902|EP15R_MOUSE  Epidermal growth factor receptor subs...    83   1e-15
sp|P42566|EP15_HUMAN  Epidermal growth factor receptor subst...    82   2e-15
sp|Q9UBC2|EP15R_HUMAN  Epidermal growth factor receptor subs...    80   5e-15
>sp|Q9H4M9|EHD1_HUMAN EH-domain containing protein 1 (Testilin) (hPAST1)
          Length = 534

 Score =  236 bits (603), Expect = 4e-62
 Identities = 120/212 (56%), Positives = 148/212 (69%)
 Frame = +3

Query: 3   HAFIISSLQSEMPSILGKESKKKELIQNLQGIYDKISRMHSISPGDFPKIERMQNLLPDH 182
           HA+IISSL+ EMP++ GKESKKKEL+ NL  IY KI R H ISPGDFP + +MQ LL   
Sbjct: 307 HAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISPGDFPSLRKMQELLQTQ 366

Query: 183 DFKAFSPMKQKLIDAVDDMLANDIAKLMQMIPKEQTTQVEFSTPVKGGAFEVQHDNPFGI 362
           DF  F  +K KL+D VDDMLANDIA+LM M+ +E++     S  VKGGAF+   + PFG 
Sbjct: 367 DFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMP--SQVVKGGAFDGTMNGPFGH 424

Query: 363 GASEGINRGRFDTEWAVLKYKNEYDRIFKGLQPVNGKINGTTAKDYMVQTKLPYNILGKI 542
           G  EG   G  D EW V K K  YD IF  L PVNGKI G  AK  MV++KLP  +LGKI
Sbjct: 425 GYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTVLGKI 484

Query: 543 WKLSDIDLDGALDEDEFALALYLVRLKLDNEE 638
           WKL+D+D DG LD++EFALA +L+++KL+  E
Sbjct: 485 WKLADVDKDGLLDDEEFALANHLIKVKLEGHE 516
>sp|Q9WVK4|EHD1_MOUSE EH-domain containing protein 1 (mPAST1)
          Length = 534

 Score =  234 bits (596), Expect = 3e-61
 Identities = 119/212 (56%), Positives = 147/212 (69%)
 Frame = +3

Query: 3   HAFIISSLQSEMPSILGKESKKKELIQNLQGIYDKISRMHSISPGDFPKIERMQNLLPDH 182
           HA+IISSL+ EMP++ GKESKKKEL+ NL  IY KI R H IS GDFP + +MQ LL   
Sbjct: 307 HAYIISSLKKEMPNVFGKESKKKELVNNLGEIYQKIEREHQISSGDFPSLRKMQELLQTQ 366

Query: 183 DFKAFSPMKQKLIDAVDDMLANDIAKLMQMIPKEQTTQVEFSTPVKGGAFEVQHDNPFGI 362
           DF  F  +K KL+D VDDMLANDIA+LM M+ +E++     S  VKGGAF+   + PFG 
Sbjct: 367 DFSKFQALKPKLLDTVDDMLANDIARLMVMVRQEESLMP--SQAVKGGAFDGTMNGPFGH 424

Query: 363 GASEGINRGRFDTEWAVLKYKNEYDRIFKGLQPVNGKINGTTAKDYMVQTKLPYNILGKI 542
           G  EG   G  D EW V K K  YD IF  L PVNGKI G  AK  MV++KLP  +LGKI
Sbjct: 425 GYGEGAGEGIDDVEWVVGKDKPTYDEIFYTLSPVNGKITGANAKKEMVKSKLPNTVLGKI 484

Query: 543 WKLSDIDLDGALDEDEFALALYLVRLKLDNEE 638
           WKL+D+D DG LD++EFALA +L+++KL+  E
Sbjct: 485 WKLADVDKDGLLDDEEFALANHLIKVKLEGHE 516
>sp|Q9NZN3|EHD3_HUMAN EH-domain containing protein 3
          Length = 546

 Score =  230 bits (586), Expect = 4e-60
 Identities = 116/212 (54%), Positives = 150/212 (70%)
 Frame = +3

Query: 3   HAFIISSLQSEMPSILGKESKKKELIQNLQGIYDKISRMHSISPGDFPKIERMQNLLPDH 182
           HA+IISSL+ EMPS+ GK++KKKEL+ NL  IY +I R H ISPGDFP ++RMQ+ L   
Sbjct: 307 HAYIISSLKKEMPSVFGKDNKKKELVNNLAEIYGRIEREHQISPGDFPNLKRMQDQLQAQ 366

Query: 183 DFKAFSPMKQKLIDAVDDMLANDIAKLMQMIPKEQTTQVEFSTPVKGGAFEVQHDNPFGI 362
           DF  F P+K KL++ VDDMLA+DIA+LM ++ +E++ +      VKGGAFE     PFG 
Sbjct: 367 DFSKFQPLKSKLLEVVDDMLAHDIAQLMVLVRQEESQRP--IQMVKGGAFEGTLHGPFGH 424

Query: 363 GASEGINRGRFDTEWAVLKYKNEYDRIFKGLQPVNGKINGTTAKDYMVQTKLPYNILGKI 542
           G  EG   G  D EW V + K  YD IF  L PV+GKI G  AK  MV++KLP ++LGKI
Sbjct: 425 GYGEGAGEGIDDAEWVVARDKPMYDEIFYTLSPVDGKITGANAKKEMVRSKLPNSVLGKI 484

Query: 543 WKLSDIDLDGALDEDEFALALYLVRLKLDNEE 638
           WKL+DID DG LD+DEFALA +L+++KL+  E
Sbjct: 485 WKLADIDKDGMLDDDEFALANHLIKVKLEGHE 516
>sp|Q9QXY6|EHD3_MOUSE EH-domain containing protein 3
          Length = 535

 Score =  229 bits (584), Expect = 7e-60
 Identities = 115/212 (54%), Positives = 150/212 (70%)
 Frame = +3

Query: 3   HAFIISSLQSEMPSILGKESKKKELIQNLQGIYDKISRMHSISPGDFPKIERMQNLLPDH 182
           HA+IISSL+ EMPS+ GK++KKKEL+ NL  IY +I R H ISPGDFP +++MQ+ L   
Sbjct: 307 HAYIISSLKKEMPSVFGKDTKKKELVNNLAEIYGRIEREHQISPGDFPNLKKMQDQLQAQ 366

Query: 183 DFKAFSPMKQKLIDAVDDMLANDIAKLMQMIPKEQTTQVEFSTPVKGGAFEVQHDNPFGI 362
           DF  F P+K KL++ VDDMLA+DIA+LM ++ +E+T +      VKGGAFE     PFG 
Sbjct: 367 DFSKFQPLKSKLLEVVDDMLAHDIAQLMVLVRQEETQRP--VQMVKGGAFEGTLQGPFGH 424

Query: 363 GASEGINRGRFDTEWAVLKYKNEYDRIFKGLQPVNGKINGTTAKDYMVQTKLPYNILGKI 542
           G  EG   G  D EW V + K  YD IF  L PV+GKI G  AK  MV++KLP ++LGKI
Sbjct: 425 GYGEGAGEGIDDAEWVVARDKPMYDEIFYTLSPVDGKITGANAKKEMVRSKLPNSVLGKI 484

Query: 543 WKLSDIDLDGALDEDEFALALYLVRLKLDNEE 638
           WKL+DID DG LD++EFALA +L+++KL+  E
Sbjct: 485 WKLADIDKDGMLDDEEFALANHLIKVKLEGHE 516
>sp|Q9H223|EHD4_HUMAN EH-domain containing protein 4 (Hepatocellular carcinoma-associated
           protein 10/11)
          Length = 541

 Score =  213 bits (541), Expect = 6e-55
 Identities = 110/215 (51%), Positives = 147/215 (68%), Gaps = 3/215 (1%)
 Frame = +3

Query: 3   HAFIISSLQSEMPSILGKESKKKELIQNLQGIYDKISRMHSISPGDFPKIERMQNLLPDH 182
           HA+IIS L+ EMPS+ GKE+KK+ELI  L  IY ++ R + IS GDFP+++ MQ  L ++
Sbjct: 310 HAYIISYLKKEMPSVFGKENKKRELISRLPEIYIQLQREYQISAGDFPEVKAMQEQLENY 369

Query: 183 DFKAFSPMKQKLIDAVDDMLANDIAKLMQMIPKEQTTQVEFSTP---VKGGAFEVQHDNP 353
           DF  F  +K KLI+AVD+ML+N I+ LM +I +E+T     STP   V+GGAF+   + P
Sbjct: 370 DFTKFHSLKPKLIEAVDNMLSNKISPLMNLISQEET-----STPTQLVQGGAFDGTTEGP 424

Query: 354 FGIGASEGINRGRFDTEWAVLKYKNEYDRIFKGLQPVNGKINGTTAKDYMVQTKLPYNIL 533
           F  G  EG   G  + EW V K K  YD +F  L P+NGKI+G  AK  MV +KLP ++L
Sbjct: 425 FNQGYGEGAKEGADEEEWVVAKDKPVYDELFYTLSPINGKISGVNAKKEMVTSKLPNSVL 484

Query: 534 GKIWKLSDIDLDGALDEDEFALALYLVRLKLDNEE 638
           GKIWKL+D D DG LDE+EFALA +L+++KLD  E
Sbjct: 485 GKIWKLADCDCDGMLDEEEFALAKHLIKIKLDGYE 519
>sp|Q9EQP2|EHD4_MOUSE EH-domain containing protein 4 (mPAST2)
          Length = 541

 Score =  206 bits (524), Expect = 6e-53
 Identities = 105/212 (49%), Positives = 143/212 (67%)
 Frame = +3

Query: 3   HAFIISSLQSEMPSILGKESKKKELIQNLQGIYDKISRMHSISPGDFPKIERMQNLLPDH 182
           HA+IIS L+ EMP++ GKE+KK+ELI  L  IY ++ R + IS GDFP+++ MQ  L ++
Sbjct: 310 HAYIISYLKKEMPNMFGKENKKRELIYRLPEIYVQLQREYQISAGDFPEVKAMQEQLENY 369

Query: 183 DFKAFSPMKQKLIDAVDDMLANDIAKLMQMIPKEQTTQVEFSTPVKGGAFEVQHDNPFGI 362
           DF  F  +K KLI+AVD+ML N I+ LM +I +E+      +  V+GGAF+   + PF  
Sbjct: 370 DFTKFHSLKPKLIEAVDNMLTNKISSLMGLISQEEMNMP--TQMVQGGAFDGTTEGPFNQ 427

Query: 363 GASEGINRGRFDTEWAVLKYKNEYDRIFKGLQPVNGKINGTTAKDYMVQTKLPYNILGKI 542
           G  EG   G  + EW V K K  YD +F  L P+NGKI+G  AK  MV +KLP ++LGKI
Sbjct: 428 GYGEGAKEGADEEEWVVAKDKPVYDELFYTLSPINGKISGVNAKKEMVTSKLPNSVLGKI 487

Query: 543 WKLSDIDLDGALDEDEFALALYLVRLKLDNEE 638
           WKL+D D DG LDE+EFALA +L+++KLD  E
Sbjct: 488 WKLADCDCDGMLDEEEFALAKHLIKIKLDGYE 519
>sp|Q9NZN4|EHD2_HUMAN EH-domain containing protein 2
          Length = 543

 Score =  206 bits (523), Expect = 8e-53
 Identities = 108/214 (50%), Positives = 145/214 (67%), Gaps = 5/214 (2%)
 Frame = +3

Query: 3   HAFIISSLQSEMPSILGKESKKKELIQNLQGIYDKISRMHSISPGDFPKIERMQNLLPDH 182
           HA+IIS L+ EMPS+ GKE+KKK+LI  L  I+ KI   H ISPGDFP  ++MQ LL  H
Sbjct: 307 HAYIISYLKKEMPSVFGKENKKKQLILKLPVIFAKIQLEHHISPGDFPDCQKMQELLMAH 366

Query: 183 DFKAFSPMKQKLIDAVDDMLANDIAKLMQMIPKEQTTQVEFSTPVKGGAFEVQHDNPF-G 359
           DF  F  +K KL++A+D+ML +DIAKLM ++ +E+    E    V+GGAFE  H  PF  
Sbjct: 367 DFTKFHSLKPKLLEALDEMLTHDIAKLMPLLRQEELESTEVG--VQGGAFEGTHMGPFVE 424

Query: 360 IGASEGINRGR----FDTEWAVLKYKNEYDRIFKGLQPVNGKINGTTAKDYMVQTKLPYN 527
            G  E +  G      + EW V K K++YD IF  L P +GK++G+ AK +MV TKLP +
Sbjct: 425 RGPDEAMEDGEEGSDDEAEWVVTKDKSKYDEIFYNLAPADGKLSGSKAKTWMVGTKLPNS 484

Query: 528 ILGKIWKLSDIDLDGALDEDEFALALYLVRLKLD 629
           +LG+IWKLSD+D DG LD++EFALA +L+  KL+
Sbjct: 485 VLGRIWKLSDVDRDGMLDDEEFALASHLIEAKLE 518
>sp|Q60902|EP15R_MOUSE Epidermal growth factor receptor substrate 15-like 1 (Eps15-related
           protein) (Eps15R) (Epidermal growth factor receptor
           pathway substrate 15-related sequence) (Eps15-rs)
          Length = 907

 Score = 82.8 bits (203), Expect = 1e-15
 Identities = 39/81 (48%), Positives = 58/81 (71%), Gaps = 1/81 (1%)
 Frame = +3

Query: 396 DTEWAV-LKYKNEYDRIFKGLQPVNGKINGTTAKDYMVQTKLPYNILGKIWKLSDIDLDG 572
           +T WAV ++ K ++D IF+ L PVNG ++G   K  ++ +KLP ++LG++W LSDID DG
Sbjct: 118 ETHWAVRVEEKAKFDGIFESLLPVNGLLSGDKVKPVLMNSKLPLDVLGRVWDLSDIDKDG 177

Query: 573 ALDEDEFALALYLVRLKLDNE 635
            LD DEFA+A++LV   L+ E
Sbjct: 178 HLDRDEFAVAMHLVYRALEKE 198

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 23/69 (33%), Positives = 40/69 (57%), Gaps = 1/69 (1%)
 Frame = +3

Query: 423 KNEYDRIF-KGLQPVNGKINGTTAKDYMVQTKLPYNILGKIWKLSDIDLDGALDEDEFAL 599
           K  +D IF K    ++G ++G   K+  + + L  N+L  IW L+D    G L +++FAL
Sbjct: 274 KMRFDEIFLKTDLDLDGYVSGQEVKEIFMHSGLTQNLLAHIWALADTRQTGKLSKEQFAL 333

Query: 600 ALYLVRLKL 626
           A+Y ++ K+
Sbjct: 334 AMYFIQQKV 342

 Score = 38.9 bits (89), Expect = 0.017
 Identities = 22/62 (35%), Positives = 36/62 (58%), Gaps = 1/62 (1%)
 Frame = +3

Query: 432 YDRIFKGLQPV-NGKINGTTAKDYMVQTKLPYNILGKIWKLSDIDLDGALDEDEFALALY 608
           Y+  +K + P   G++  + A  ++ ++ L   ILGKIW L+D +  G LD+  F +AL 
Sbjct: 19  YESYYKQVDPAYTGRVGASEAALFLKKSGLSDIILGKIWDLADPEGKGFLDKQGFYVALR 78

Query: 609 LV 614
           LV
Sbjct: 79  LV 80
>sp|P42566|EP15_HUMAN Epidermal growth factor receptor substrate 15 (Protein Eps15)
           (AF-1p protein)
          Length = 896

 Score = 82.0 bits (201), Expect = 2e-15
 Identities = 40/78 (51%), Positives = 55/78 (70%), Gaps = 1/78 (1%)
 Frame = +3

Query: 405 WAVL-KYKNEYDRIFKGLQPVNGKINGTTAKDYMVQTKLPYNILGKIWKLSDIDLDGALD 581
           WAV  + K +YD IF  L PVNG ++G   K  ++ +KLP +ILG++W+LSDID DG LD
Sbjct: 122 WAVKPEDKAKYDAIFDSLSPVNGFLSGDKVKPVLLNSKLPVDILGRVWELSDIDHDGMLD 181

Query: 582 EDEFALALYLVRLKLDNE 635
            DEFA+A++LV   L+ E
Sbjct: 182 RDEFAVAMFLVYCALEKE 199

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 26/69 (37%), Positives = 41/69 (59%), Gaps = 1/69 (1%)
 Frame = +3

Query: 423 KNEYDRIF-KGLQPVNGKINGTTAKDYMVQTKLPYNILGKIWKLSDIDLDGALDEDEFAL 599
           K +YD IF K  + ++G ++G   ++  ++T LP  +L  IW L D    G L +D+FAL
Sbjct: 225 KAKYDEIFLKTDKDMDGFVSGLEVREIFLKTGLPSTLLAHIWSLCDTKDCGKLSKDQFAL 284

Query: 600 ALYLVRLKL 626
           A +L+  KL
Sbjct: 285 AFHLISQKL 293

 Score = 43.1 bits (100), Expect = 9e-04
 Identities = 23/62 (37%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
 Frame = +3

Query: 432 YDRIFKGLQPVN-GKINGTTAKDYMVQTKLPYNILGKIWKLSDIDLDGALDEDEFALALY 608
           Y++ ++ +   N G++  + A  ++ ++ LP  ILGKIW L+D D  G L++ EF +AL 
Sbjct: 19  YEKYYRQVDTGNTGRVLASDAAAFLKKSGLPDLILGKIWDLADTDGKGILNKQEFFVALR 78

Query: 609 LV 614
           LV
Sbjct: 79  LV 80
>sp|Q9UBC2|EP15R_HUMAN Epidermal growth factor receptor substrate 15-like 1 (Eps15-related
           protein) (Eps15R)
          Length = 864

 Score = 80.5 bits (197), Expect = 5e-15
 Identities = 37/81 (45%), Positives = 57/81 (70%), Gaps = 1/81 (1%)
 Frame = +3

Query: 396 DTEWAV-LKYKNEYDRIFKGLQPVNGKINGTTAKDYMVQTKLPYNILGKIWKLSDIDLDG 572
           +  WAV ++ K ++D IF+ L P+NG ++G   K  ++ +KLP ++LG++W LSDID DG
Sbjct: 118 EAHWAVRVEEKAKFDGIFESLLPINGLLSGDKVKPVLMNSKLPLDVLGRVWDLSDIDKDG 177

Query: 573 ALDEDEFALALYLVRLKLDNE 635
            LD DEFA+A++LV   L+ E
Sbjct: 178 HLDRDEFAVAMHLVYRALEKE 198

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 30/109 (27%), Positives = 52/109 (47%), Gaps = 2/109 (1%)
 Frame = +3

Query: 306 STPVKGGAFEVQHDNPFGIGASEGINRGRFDTEWAV-LKYKNEYDRIF-KGLQPVNGKIN 479
           STP  G    +       +     + + +    W V +  K  +D IF K    ++G ++
Sbjct: 238 STPSHGSVSSLNSTG--SLSPKHSLKQTQPTVNWVVPVADKMRFDEIFLKTDLDLDGYVS 295

Query: 480 GTTAKDYMVQTKLPYNILGKIWKLSDIDLDGALDEDEFALALYLVRLKL 626
           G   K+  + + L  N+L  IW L+D    G L +D+FALA+Y ++ K+
Sbjct: 296 GQEVKEIFMHSGLTQNLLAHIWALADTRQTGKLSKDQFALAMYFIQQKV 344

 Score = 38.9 bits (89), Expect = 0.017
 Identities = 22/62 (35%), Positives = 36/62 (58%), Gaps = 1/62 (1%)
 Frame = +3

Query: 432 YDRIFKGLQPV-NGKINGTTAKDYMVQTKLPYNILGKIWKLSDIDLDGALDEDEFALALY 608
           Y+  +K + P   G++  + A  ++ ++ L   ILGKIW L+D +  G LD+  F +AL 
Sbjct: 19  YESYYKQVDPAYTGRVGASEAALFLKKSGLSDIILGKIWDLADPEGKGFLDKQGFYVALR 78

Query: 609 LV 614
           LV
Sbjct: 79  LV 80
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 90,434,195
Number of Sequences: 369166
Number of extensions: 1785141
Number of successful extensions: 5130
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4902
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5119
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7666799535
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)