Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_02329 (926 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q9H8V3|ECT2_HUMAN ECT2 protein (Epithelial cell transfor... 36 0.13 sp|Q9H329|E41LB_HUMAN Band 4.1-like protein 4B (EHM2 protei... 33 1.1 sp|Q07139|ECT2_MOUSE ECT2 protein (Epithelial cell transfor... 32 1.9 sp|Q9JMC8|E41LB_MOUSE Band 4.1-like protein 4B (EHM2 protein) 32 2.5 sp|Q8BRH4|MLL3_MOUSE Myeloid/lymphoid or mixed-lineage leuk... 32 2.5 sp|Q03213|YM41_YEAST Hypothetical 79.4 kDa protein in ALD2-... 32 3.3 sp|Q9UUI4|YIY9_SCHPO Hypothetical protein C22F8.09 in chrom... 31 5.6 sp|Q9YID8|POLG_EC23C Genome polyprotein [Contains: Coat pro... 31 5.6 sp|P48193|41_MOUSE Protein 4.1 (Band 4.1) (P4.1) (4.1R) 30 7.4 sp|P20929|NEBU_HUMAN Nebulin 30 7.4
>sp|Q9H8V3|ECT2_HUMAN ECT2 protein (Epithelial cell transforming sequence 2 oncogene) Length = 883 Score = 36.2 bits (82), Expect = 0.13 Identities = 47/180 (26%), Positives = 73/180 (40%), Gaps = 14/180 (7%) Frame = +2 Query: 269 EIQQSVSMLYLNNPNINELSRR-NTILRDVVQEKDLEEANKAKYNTMPSRER----GTML 433 E+++SVSML LN PN N RR L + ++ D+ K PS E G++L Sbjct: 330 ELKKSVSMLSLNTPNSNRKRRRLKETLAQLSRDTDVSPFPPRK---RPSAEHSLSIGSLL 386 Query: 434 GTQDTLDSLFIPNHHGSVDNAASHSPINTPVDSPK------LLERKHTESQRTQSLDHIL 595 +T +S N+ + + S +TPV S + E TES L I+ Sbjct: 387 DISNTPESSI--NYGDTPKSCTKSSKSSTPVPSKQSARWQVAKELYQTESNYVNILATII 444 Query: 596 EEPCIPEQREYTK---YLMTEDRKXXXXXXXXXXXXXXXLNDTIDSGSINTKLSSSHGDI 766 + +P + E + L E+ K + D ++ +N S S GDI Sbjct: 445 QLFQVPLEEEGQRGGPILAPEEIKTIFGSIPDIFDVHTKIKDDLEDLIVNWDESKSIGDI 504
>sp|Q9H329|E41LB_HUMAN Band 4.1-like protein 4B (EHM2 protein) (FERM-containing protein CG1) Length = 913 Score = 33.1 bits (74), Expect = 1.1 Identities = 34/161 (21%), Positives = 63/161 (39%), Gaps = 8/161 (4%) Frame = +2 Query: 83 KKKHVLGFKCETSVAACALWKWANDRMCFFSLNRSSEAKRVKSGGGIFKKRKTFKFAGRC 262 +++H F+ +++ LWK A + FF L +K +S + F+F+GR Sbjct: 322 EQEHTFVFRLDSARTCKHLWKCAVEHHAFFRLRTPGNSKSNRS--DFIRLGSRFRFSGRT 379 Query: 263 QKEIQQSVSM----LYLNNPNINELSRRNTILR---DVVQEKDLEEANKAKYNTMPSRER 421 + + + + P+ SRR++ + V+ + + N +N P Sbjct: 380 EYQATHGSRLRRTSTFERKPSKRYPSRRHSTFKASNPVIAAQLCSKTNPEVHNYQPQ--- 436 Query: 422 GTMLGTQDTLDSLFIPNHHGSVDNAASHSP-INTPVDSPKL 541 + PN H S HSP ++ P+ SP L Sbjct: 437 -------------YHPNIHPSQPRWHPHSPNVSYPLPSPVL 464
>sp|Q07139|ECT2_MOUSE ECT2 protein (Epithelial cell transforming sequence 2 oncogene) Length = 738 Score = 32.3 bits (72), Expect = 1.9 Identities = 46/181 (25%), Positives = 71/181 (39%), Gaps = 15/181 (8%) Frame = +2 Query: 269 EIQQSVSMLYLNNPNINELSRR-NTILRDVVQEKDLEEANKAKYNTMPSRER----GTML 433 E+++SVS+L L+ PN N RR L + +E DL K PS E G++L Sbjct: 186 ELKKSVSLLSLSTPNSNRKRRRLKETLAQLSRETDLSPFPPRK---RPSAEHSLSIGSLL 242 Query: 434 GTQDTLDSLFIPNHHGSVDNAASHSPINTPVDSPK-------LLERKHTESQRTQSLDHI 592 +T +S H+G + + S ++ PK E TES L I Sbjct: 243 DISNTPESSI---HYGETPKSCAKSSRSSTPVPPKQSARWQVAKELYQTESNYVNILATI 299 Query: 593 LEEPCIPEQREYTK---YLMTEDRKXXXXXXXXXXXXXXXLNDTIDSGSINTKLSSSHGD 763 ++ +P + E + L E+ K + D ++ N S S GD Sbjct: 300 IQLFQVPLEEEGQRGGPILAPEEIKTIFGSIPDIFDVHMKIKDDLEDLIANWDESRSIGD 359 Query: 764 I 766 I Sbjct: 360 I 360
>sp|Q9JMC8|E41LB_MOUSE Band 4.1-like protein 4B (EHM2 protein) Length = 527 Score = 32.0 bits (71), Expect = 2.5 Identities = 24/116 (20%), Positives = 50/116 (43%), Gaps = 7/116 (6%) Frame = +2 Query: 83 KKKHVLGFKCETSVAACALWKWANDRMCFFSLNRSSEAKRVKSGGGIFKKRKTFKFAGRC 262 +++H F+ +++ LWK A + FF L S +K +S + F+F+GR Sbjct: 336 EQEHTFVFRLDSARTCKHLWKCAVEHHAFFRLRTPSNSKSARS--DFIRLGSRFRFSGRT 393 Query: 263 QKEIQQSVSM----LYLNNPNINELSRRNTILR---DVVQEKDLEEANKAKYNTMP 409 + + + + P+ SRR++ + ++ + +AN +N P Sbjct: 394 EYQATHGSRLRRTSTFERKPSKRYPSRRHSTFKASNPIIAAQLCSKANPEVHNYQP 449
>sp|Q8BRH4|MLL3_MOUSE Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) Length = 4903 Score = 32.0 bits (71), Expect = 2.5 Identities = 23/78 (29%), Positives = 34/78 (43%), Gaps = 2/78 (2%) Frame = +2 Query: 386 KAKYNTMPSRERGTMLGTQDTLDSLFIPNHHGSVDNA--ASHSPINTPVDSPKLLERKHT 559 +A N +P G ++ DT P G +D AS S + P D P + R H+ Sbjct: 2245 QAAQNRVPGLP-GPLIRPPDTCSQTPRPPGPGRIDTFTHASSSAVRDPYDQPPVTPRPHS 2303 Query: 560 ESQRTQSLDHILEEPCIP 613 ES T + H L + +P Sbjct: 2304 ESFGTSQVVHDLVDRPVP 2321
>sp|Q03213|YM41_YEAST Hypothetical 79.4 kDa protein in ALD2-DDR48 intergenic region Length = 719 Score = 31.6 bits (70), Expect = 3.3 Identities = 31/117 (26%), Positives = 52/117 (44%), Gaps = 11/117 (9%) Frame = +2 Query: 272 IQQSVSMLYLNNPNINELSRRNTILRDVVQEKDLEEANKAKYNTMPSRERGTMLGTQDTL 451 I + + LNN N L NTIL D Q+ + ++ ++P+R+ G ++ TQ Sbjct: 287 IDVNTNTAQLNNQFSNAL---NTILPD--QQHNRNNVSQNINQSLPNRQLGPVINTQANQ 341 Query: 452 DSLFIPNHHGSVDNAASHSPINTP---VDSPKLL-------ERKHTESQRTQSL-DH 589 + + H+ + + SPI+ P D P L R++T+S S DH Sbjct: 342 NQSQVLIHNTNTHQQVNRSPISFPNASTDKPFKLNPNGIKRRRRNTQSNNNASTNDH 398
>sp|Q9UUI4|YIY9_SCHPO Hypothetical protein C22F8.09 in chromosome I Length = 419 Score = 30.8 bits (68), Expect = 5.6 Identities = 19/62 (30%), Positives = 30/62 (48%) Frame = +2 Query: 470 NHHGSVDNAASHSPINTPVDSPKLLERKHTESQRTQSLDHILEEPCIPEQREYTKYLMTE 649 NH D+ + H TP+ S K ++ T SQR + EE + EQ++ + L T Sbjct: 247 NHSIDSDDQSEHEQAETPIPSSK--NKRKTRSQRNKIRQRREEELRLLEQKKNEELLRTI 304 Query: 650 DR 655 D+ Sbjct: 305 DK 306
>sp|Q9YID8|POLG_EC23C Genome polyprotein [Contains: Coat protein VP0 (P1AB); Coat protein VP3 (P1C); Coat protein VP1 (P1D); Picornain 2A (Core protein P2A); Core protein P2B; Core protein P2C; Core protein P3A; Genome-linked protein VPg (P3B); Picornain 3C (Protease 3C) (P3C); RNA-directed RNA polymerase (P3D)] Length = 2188 Score = 30.8 bits (68), Expect = 5.6 Identities = 16/41 (39%), Positives = 24/41 (58%) Frame = -1 Query: 668 CEYSSDPLSLGI*CIPFVLEYMVLLRYDREIEYVGIQYAFA 546 C Y+++ +S G+ C+P V V+L DREIE +Q A Sbjct: 2033 CIYTTNLISPGVDCLPIVYGDDVILSLDREIEPERLQSIMA 2073
>sp|P48193|41_MOUSE Protein 4.1 (Band 4.1) (P4.1) (4.1R) Length = 858 Score = 30.4 bits (67), Expect = 7.4 Identities = 19/76 (25%), Positives = 36/76 (47%), Gaps = 3/76 (3%) Frame = +2 Query: 77 PSKKKH---VLGFKCETSVAACALWKWANDRMCFFSLNRSSEAKRVKSGGGIFKKRKTFK 247 P +++H +GFK + AA LWK + FF L + + K F+ Sbjct: 454 PGEQEHYESTIGFKLPSYRAAKKLWKVCVEHHTFFRLTSTDTIPKSK----FLALGSKFR 509 Query: 248 FAGRCQKEIQQSVSML 295 ++GR Q + +Q+ +++ Sbjct: 510 YSGRTQAQTRQASALI 525
>sp|P20929|NEBU_HUMAN Nebulin Length = 6669 Score = 30.4 bits (67), Expect = 7.4 Identities = 40/177 (22%), Positives = 59/177 (33%), Gaps = 2/177 (1%) Frame = +2 Query: 134 ALWKWANDRMCFFSLNRSSEAKRVKSGGGIFKKRKTFKFAGRCQKEIQQSVSMLYLNNPN 313 A WKW DR F +SS Q + + + +L Sbjct: 5556 AHWKWTPDRPDFLQAAKSSLQ----------------------QSDFEYKLDREFLKGCK 5593 Query: 314 INELSRRNTI--LRDVVQEKDLEEANKAKYNTMPSRERGTMLGTQDTLDSLFIPNHHGSV 487 ++ +NT+ LR+ + E DL KY +ERGT DT L +V Sbjct: 5594 LSVTDDKNTVLALRNTLIESDL------KYKEKHVKERGTCHAVPDTPQILLAK----TV 5643 Query: 488 DNAASHSPINTPVDSPKLLERKHTESQRTQSLDHILEEPCIPEQREYTKYLMTEDRK 658 N S + V L + +T T+ H+ E Y K + E K Sbjct: 5644 SNLVSENKYKDHV-KKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGK 5699
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 102,639,409 Number of Sequences: 369166 Number of extensions: 2028726 Number of successful extensions: 6007 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 5671 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6003 length of database: 68,354,980 effective HSP length: 110 effective length of database: 48,034,130 effective search space used: 9510757740 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)