Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_018_M16
(926 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9H8V3|ECT2_HUMAN ECT2 protein (Epithelial cell transfor... 36 0.13
sp|Q9H329|E41LB_HUMAN Band 4.1-like protein 4B (EHM2 protei... 33 1.1
sp|Q07139|ECT2_MOUSE ECT2 protein (Epithelial cell transfor... 32 1.9
sp|Q9JMC8|E41LB_MOUSE Band 4.1-like protein 4B (EHM2 protein) 32 2.5
sp|Q8BRH4|MLL3_MOUSE Myeloid/lymphoid or mixed-lineage leuk... 32 2.5
sp|Q03213|YM41_YEAST Hypothetical 79.4 kDa protein in ALD2-... 32 3.3
sp|Q9UUI4|YIY9_SCHPO Hypothetical protein C22F8.09 in chrom... 31 5.6
sp|Q9YID8|POLG_EC23C Genome polyprotein [Contains: Coat pro... 31 5.6
sp|P48193|41_MOUSE Protein 4.1 (Band 4.1) (P4.1) (4.1R) 30 7.4
sp|P20929|NEBU_HUMAN Nebulin 30 7.4
>sp|Q9H8V3|ECT2_HUMAN ECT2 protein (Epithelial cell transforming sequence 2 oncogene)
Length = 883
Score = 36.2 bits (82), Expect = 0.13
Identities = 47/180 (26%), Positives = 73/180 (40%), Gaps = 14/180 (7%)
Frame = +2
Query: 269 EIQQSVSMLYLNNPNINELSRR-NTILRDVVQEKDLEEANKAKYNTMPSRER----GTML 433
E+++SVSML LN PN N RR L + ++ D+ K PS E G++L
Sbjct: 330 ELKKSVSMLSLNTPNSNRKRRRLKETLAQLSRDTDVSPFPPRK---RPSAEHSLSIGSLL 386
Query: 434 GTQDTLDSLFIPNHHGSVDNAASHSPINTPVDSPK------LLERKHTESQRTQSLDHIL 595
+T +S N+ + + S +TPV S + E TES L I+
Sbjct: 387 DISNTPESSI--NYGDTPKSCTKSSKSSTPVPSKQSARWQVAKELYQTESNYVNILATII 444
Query: 596 EEPCIPEQREYTK---YLMTEDRKXXXXXXXXXXXXXXXLNDTIDSGSINTKLSSSHGDI 766
+ +P + E + L E+ K + D ++ +N S S GDI
Sbjct: 445 QLFQVPLEEEGQRGGPILAPEEIKTIFGSIPDIFDVHTKIKDDLEDLIVNWDESKSIGDI 504
>sp|Q9H329|E41LB_HUMAN Band 4.1-like protein 4B (EHM2 protein) (FERM-containing protein
CG1)
Length = 913
Score = 33.1 bits (74), Expect = 1.1
Identities = 34/161 (21%), Positives = 63/161 (39%), Gaps = 8/161 (4%)
Frame = +2
Query: 83 KKKHVLGFKCETSVAACALWKWANDRMCFFSLNRSSEAKRVKSGGGIFKKRKTFKFAGRC 262
+++H F+ +++ LWK A + FF L +K +S + F+F+GR
Sbjct: 322 EQEHTFVFRLDSARTCKHLWKCAVEHHAFFRLRTPGNSKSNRS--DFIRLGSRFRFSGRT 379
Query: 263 QKEIQQSVSM----LYLNNPNINELSRRNTILR---DVVQEKDLEEANKAKYNTMPSRER 421
+ + + + P+ SRR++ + V+ + + N +N P
Sbjct: 380 EYQATHGSRLRRTSTFERKPSKRYPSRRHSTFKASNPVIAAQLCSKTNPEVHNYQPQ--- 436
Query: 422 GTMLGTQDTLDSLFIPNHHGSVDNAASHSP-INTPVDSPKL 541
+ PN H S HSP ++ P+ SP L
Sbjct: 437 -------------YHPNIHPSQPRWHPHSPNVSYPLPSPVL 464
>sp|Q07139|ECT2_MOUSE ECT2 protein (Epithelial cell transforming sequence 2 oncogene)
Length = 738
Score = 32.3 bits (72), Expect = 1.9
Identities = 46/181 (25%), Positives = 71/181 (39%), Gaps = 15/181 (8%)
Frame = +2
Query: 269 EIQQSVSMLYLNNPNINELSRR-NTILRDVVQEKDLEEANKAKYNTMPSRER----GTML 433
E+++SVS+L L+ PN N RR L + +E DL K PS E G++L
Sbjct: 186 ELKKSVSLLSLSTPNSNRKRRRLKETLAQLSRETDLSPFPPRK---RPSAEHSLSIGSLL 242
Query: 434 GTQDTLDSLFIPNHHGSVDNAASHSPINTPVDSPK-------LLERKHTESQRTQSLDHI 592
+T +S H+G + + S ++ PK E TES L I
Sbjct: 243 DISNTPESSI---HYGETPKSCAKSSRSSTPVPPKQSARWQVAKELYQTESNYVNILATI 299
Query: 593 LEEPCIPEQREYTK---YLMTEDRKXXXXXXXXXXXXXXXLNDTIDSGSINTKLSSSHGD 763
++ +P + E + L E+ K + D ++ N S S GD
Sbjct: 300 IQLFQVPLEEEGQRGGPILAPEEIKTIFGSIPDIFDVHMKIKDDLEDLIANWDESRSIGD 359
Query: 764 I 766
I
Sbjct: 360 I 360
>sp|Q9JMC8|E41LB_MOUSE Band 4.1-like protein 4B (EHM2 protein)
Length = 527
Score = 32.0 bits (71), Expect = 2.5
Identities = 24/116 (20%), Positives = 50/116 (43%), Gaps = 7/116 (6%)
Frame = +2
Query: 83 KKKHVLGFKCETSVAACALWKWANDRMCFFSLNRSSEAKRVKSGGGIFKKRKTFKFAGRC 262
+++H F+ +++ LWK A + FF L S +K +S + F+F+GR
Sbjct: 336 EQEHTFVFRLDSARTCKHLWKCAVEHHAFFRLRTPSNSKSARS--DFIRLGSRFRFSGRT 393
Query: 263 QKEIQQSVSM----LYLNNPNINELSRRNTILR---DVVQEKDLEEANKAKYNTMP 409
+ + + + P+ SRR++ + ++ + +AN +N P
Sbjct: 394 EYQATHGSRLRRTSTFERKPSKRYPSRRHSTFKASNPIIAAQLCSKANPEVHNYQP 449
>sp|Q8BRH4|MLL3_MOUSE Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog
(Histone-lysine N-methyltransferase, H3 lysine-4 specific
MLL3)
Length = 4903
Score = 32.0 bits (71), Expect = 2.5
Identities = 23/78 (29%), Positives = 34/78 (43%), Gaps = 2/78 (2%)
Frame = +2
Query: 386 KAKYNTMPSRERGTMLGTQDTLDSLFIPNHHGSVDNA--ASHSPINTPVDSPKLLERKHT 559
+A N +P G ++ DT P G +D AS S + P D P + R H+
Sbjct: 2245 QAAQNRVPGLP-GPLIRPPDTCSQTPRPPGPGRIDTFTHASSSAVRDPYDQPPVTPRPHS 2303
Query: 560 ESQRTQSLDHILEEPCIP 613
ES T + H L + +P
Sbjct: 2304 ESFGTSQVVHDLVDRPVP 2321
>sp|Q03213|YM41_YEAST Hypothetical 79.4 kDa protein in ALD2-DDR48 intergenic region
Length = 719
Score = 31.6 bits (70), Expect = 3.3
Identities = 31/117 (26%), Positives = 52/117 (44%), Gaps = 11/117 (9%)
Frame = +2
Query: 272 IQQSVSMLYLNNPNINELSRRNTILRDVVQEKDLEEANKAKYNTMPSRERGTMLGTQDTL 451
I + + LNN N L NTIL D Q+ + ++ ++P+R+ G ++ TQ
Sbjct: 287 IDVNTNTAQLNNQFSNAL---NTILPD--QQHNRNNVSQNINQSLPNRQLGPVINTQANQ 341
Query: 452 DSLFIPNHHGSVDNAASHSPINTP---VDSPKLL-------ERKHTESQRTQSL-DH 589
+ + H+ + + SPI+ P D P L R++T+S S DH
Sbjct: 342 NQSQVLIHNTNTHQQVNRSPISFPNASTDKPFKLNPNGIKRRRRNTQSNNNASTNDH 398
>sp|Q9UUI4|YIY9_SCHPO Hypothetical protein C22F8.09 in chromosome I
Length = 419
Score = 30.8 bits (68), Expect = 5.6
Identities = 19/62 (30%), Positives = 30/62 (48%)
Frame = +2
Query: 470 NHHGSVDNAASHSPINTPVDSPKLLERKHTESQRTQSLDHILEEPCIPEQREYTKYLMTE 649
NH D+ + H TP+ S K ++ T SQR + EE + EQ++ + L T
Sbjct: 247 NHSIDSDDQSEHEQAETPIPSSK--NKRKTRSQRNKIRQRREEELRLLEQKKNEELLRTI 304
Query: 650 DR 655
D+
Sbjct: 305 DK 306
>sp|Q9YID8|POLG_EC23C Genome polyprotein [Contains: Coat protein VP0 (P1AB); Coat protein
VP3 (P1C); Coat protein VP1 (P1D); Picornain 2A (Core
protein P2A); Core protein P2B; Core protein P2C; Core
protein P3A; Genome-linked protein VPg (P3B); Picornain
3C (Protease 3C) (P3C); RNA-directed RNA polymerase
(P3D)]
Length = 2188
Score = 30.8 bits (68), Expect = 5.6
Identities = 16/41 (39%), Positives = 24/41 (58%)
Frame = -1
Query: 668 CEYSSDPLSLGI*CIPFVLEYMVLLRYDREIEYVGIQYAFA 546
C Y+++ +S G+ C+P V V+L DREIE +Q A
Sbjct: 2033 CIYTTNLISPGVDCLPIVYGDDVILSLDREIEPERLQSIMA 2073
>sp|P48193|41_MOUSE Protein 4.1 (Band 4.1) (P4.1) (4.1R)
Length = 858
Score = 30.4 bits (67), Expect = 7.4
Identities = 19/76 (25%), Positives = 36/76 (47%), Gaps = 3/76 (3%)
Frame = +2
Query: 77 PSKKKH---VLGFKCETSVAACALWKWANDRMCFFSLNRSSEAKRVKSGGGIFKKRKTFK 247
P +++H +GFK + AA LWK + FF L + + K F+
Sbjct: 454 PGEQEHYESTIGFKLPSYRAAKKLWKVCVEHHTFFRLTSTDTIPKSK----FLALGSKFR 509
Query: 248 FAGRCQKEIQQSVSML 295
++GR Q + +Q+ +++
Sbjct: 510 YSGRTQAQTRQASALI 525
>sp|P20929|NEBU_HUMAN Nebulin
Length = 6669
Score = 30.4 bits (67), Expect = 7.4
Identities = 40/177 (22%), Positives = 59/177 (33%), Gaps = 2/177 (1%)
Frame = +2
Query: 134 ALWKWANDRMCFFSLNRSSEAKRVKSGGGIFKKRKTFKFAGRCQKEIQQSVSMLYLNNPN 313
A WKW DR F +SS Q + + + +L
Sbjct: 5556 AHWKWTPDRPDFLQAAKSSLQ----------------------QSDFEYKLDREFLKGCK 5593
Query: 314 INELSRRNTI--LRDVVQEKDLEEANKAKYNTMPSRERGTMLGTQDTLDSLFIPNHHGSV 487
++ +NT+ LR+ + E DL KY +ERGT DT L +V
Sbjct: 5594 LSVTDDKNTVLALRNTLIESDL------KYKEKHVKERGTCHAVPDTPQILLAK----TV 5643
Query: 488 DNAASHSPINTPVDSPKLLERKHTESQRTQSLDHILEEPCIPEQREYTKYLMTEDRK 658
N S + V L + +T T+ H+ E Y K + E K
Sbjct: 5644 SNLVSENKYKDHV-KKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGK 5699
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 102,639,409
Number of Sequences: 369166
Number of extensions: 2028726
Number of successful extensions: 6007
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5671
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6003
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9510757740
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)