Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_02299 (709 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q9WUE4|TUSC4_MOUSE Tumor suppressor candidate 4 (NPR2-li... 86 1e-16 sp|Q8WTW4|TUSC4_HUMAN Tumor suppressor candidate 4 (NPR2-li... 85 2e-16 sp|Q63226|GRID2_RAT Glutamate receptor delta-2 subunit prec... 37 0.067 sp|O43424|GRID2_HUMAN Glutamate receptor delta-2 subunit pr... 36 0.088 sp|P39923|NPR2_YEAST Nitrogen permease regulator 2 35 0.15 sp|Q8Y4R7|G6PI_LISMO Glucose-6-phosphate isomerase (GPI) (P... 33 0.97 sp|Q9ZCZ8|IF2_RICPR Translation initiation factor IF-2 32 1.7 sp|Q7VJ31|PROB_HELHP Glutamate 5-kinase (Gamma-glutamyl kin... 32 2.2 sp|O67699|YI45_AQUAE Hypothetical protein AQ_1845 32 2.2 sp|Q9H9C1|CN133_HUMAN Protein C14orf133 31 2.8
>sp|Q9WUE4|TUSC4_MOUSE Tumor suppressor candidate 4 (NPR2-like) (Gene 21 protein) (G21 protein) Length = 380 Score = 85.9 bits (211), Expect = 1e-16 Identities = 60/226 (26%), Positives = 108/226 (47%), Gaps = 4/226 (1%) Frame = +1 Query: 19 EPNVAVECEQVPVLNNDRRII---PLDLTSQRLLPLLNGESSVWDIAQKSQVDVKVVRAC 189 +P VA E + VPV D+ DLT+Q++LP ++G V I+ ++ V++ +VR Sbjct: 165 DPPVAQEYD-VPVFTKDKEDFFSSQWDLTTQQILPYIDGFRHVQKISAEADVELNLVRIA 223 Query: 190 VQNLGYVGAIKTVAPFRLGSIYMCMPKLIRSWRDSELRRKLLEYVLNEEKNSLEIEKLEN 369 +QNL Y G + V+ + ++Y PK+ D L+ L YV + + + Sbjct: 224 IQNLLYYGVVTLVSILQYSNVYCPTPKVQDLVDDKSLQEACLSYVTKQGHKRASLRDV-- 281 Query: 370 IAETALRALAILGPQTKVSDCNTILSSTNQKFNCRQLIQFAEMEGLIRKVNGHPINIADI 549 + L P T V D Q + R+LIQF M+ LIR++ +P+ ++ Sbjct: 282 -----FQLYCSLSPGTTVRDLIGRHPQQLQHVDERKLIQFGLMKNLIRRLQKYPVRVS-- 334 Query: 550 VTDKHTIPSQLLDGTHNLEEIACMLDTPFPQLESEI-NKSDAFVIW 684 ++ + P++L G H+ +EI C + +L+ + N + + W Sbjct: 335 -REERSHPARLYTGCHSYDEICCKTGMSYHELDERLENDPNIIICW 379
>sp|Q8WTW4|TUSC4_HUMAN Tumor suppressor candidate 4 (NPR2-like) (Gene 21 protein) (G21 protein) Length = 380 Score = 85.1 bits (209), Expect = 2e-16 Identities = 59/226 (26%), Positives = 107/226 (47%), Gaps = 4/226 (1%) Frame = +1 Query: 19 EPNVAVECEQVPVLNNDRRII---PLDLTSQRLLPLLNGESSVWDIAQKSQVDVKVVRAC 189 +P VA E + VPV D+ DLT+Q++LP ++G + I+ ++ V++ +VR Sbjct: 165 DPPVAQEYD-VPVFTKDKEDFFNSQWDLTTQQILPYIDGFRHIQKISAEADVELNLVRIA 223 Query: 190 VQNLGYVGAIKTVAPFRLGSIYMCMPKLIRSWRDSELRRKLLEYVLNEEKNSLEIEKLEN 369 +QNL Y G + V+ + ++Y PK+ D L+ L YV + + + Sbjct: 224 IQNLLYYGVVTLVSILQYSNVYCPTPKVQDLVDDKSLQEACLSYVTKQGHKRASLRDV-- 281 Query: 370 IAETALRALAILGPQTKVSDCNTILSSTNQKFNCRQLIQFAEMEGLIRKVNGHPINIADI 549 + L P T V D Q + R+LIQF M+ LIR++ +P+ + Sbjct: 282 -----FQLYCSLSPGTTVRDLIGRHPQQLQHVDERKLIQFGLMKNLIRRLQKYPVR---V 333 Query: 550 VTDKHTIPSQLLDGTHNLEEIACMLDTPFPQLESEI-NKSDAFVIW 684 ++ + P++L G H+ +EI C + +L+ + N + + W Sbjct: 334 TREEQSHPARLYTGCHSYDEICCKTGMSYHELDERLENDPNIIICW 379
>sp|Q63226|GRID2_RAT Glutamate receptor delta-2 subunit precursor (GluR delta-2) Length = 1007 Score = 36.6 bits (83), Expect = 0.067 Identities = 23/106 (21%), Positives = 44/106 (41%), Gaps = 5/106 (4%) Frame = +1 Query: 340 NSLEIEKLENIAETALRALAILGPQTKVSDCNTILSSTNQKFNCRQLI-----QFAEMEG 504 +++ IE+L +T RA+ ++ P T S + ++ + F+C +I +++ Sbjct: 213 DTMRIEELNRYRDTLRRAILVMNPATAKSFISEVVETNLVAFDCHWIIINEEINDVDVQE 272 Query: 505 LIRKVNGHPINIADIVTDKHTIPSQLLDGTHNLEEIACMLDTPFPQ 642 L+R+ G I I + G H + C PF Q Sbjct: 273 LVRRSIGRLTIIRQTFPVPQNISQRCFRGNHRISSTLCDPKDPFAQ 318
>sp|O43424|GRID2_HUMAN Glutamate receptor delta-2 subunit precursor (GluR delta-2) Length = 1007 Score = 36.2 bits (82), Expect = 0.088 Identities = 23/106 (21%), Positives = 43/106 (40%), Gaps = 5/106 (4%) Frame = +1 Query: 340 NSLEIEKLENIAETALRALAILGPQTKVSDCNTILSSTNQKFNCRQLI-----QFAEMEG 504 +++ IE+L +T RA+ ++ P T S ++ + F+C +I +++ Sbjct: 213 DTMRIEELNRYRDTLRRAILVMNPATAKSFITEVVETNLVAFDCHWIIINEEINDVDVQE 272 Query: 505 LIRKVNGHPINIADIVTDKHTIPSQLLDGTHNLEEIACMLDTPFPQ 642 L+R+ G I I + G H + C PF Q Sbjct: 273 LVRRSIGRLTIIRQTFPIPQNISQRCFRGNHRISSTLCDPKDPFAQ 318
>sp|P39923|NPR2_YEAST Nitrogen permease regulator 2 Length = 624 Score = 35.4 bits (80), Expect = 0.15 Identities = 23/81 (28%), Positives = 43/81 (53%), Gaps = 3/81 (3%) Frame = +1 Query: 22 PNVAVECEQVPVLN-NDRRIIPL--DLTSQRLLPLLNGESSVWDIAQKSQVDVKVVRACV 192 P V E VP+ + N ++II + D T ++P ++G +S+ I++ S D +V C+ Sbjct: 244 PTTCVSLEDVPLSSVNLKKIIDVNWDPTMMSIVPYIDGLNSIAKISKLSNSDPGLVIECI 303 Query: 193 QNLGYVGAIKTVAPFRLGSIY 255 ++L Y + F+ +IY Sbjct: 304 RHLIYYKCVTLSDIFQFSNIY 324
>sp|Q8Y4R7|G6PI_LISMO Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI) Length = 450 Score = 32.7 bits (73), Expect = 0.97 Identities = 34/105 (32%), Positives = 44/105 (41%) Frame = +1 Query: 355 EKLENIAETALRALAILGPQTKVSDCNTILSSTNQKFNCRQLIQFAEMEGLIRKVNGHPI 534 E NIA A +L + KV++ Q FN F E EG +K G Sbjct: 244 ELKNNIAYQYAAARNVLYRKGKVTELLISYEPGLQYFNEWWKQLFGESEGKDKK--GIYP 301 Query: 535 NIADIVTDKHTIPSQLLDGTHNLEEIACMLDTPFPQLESEINKSD 669 + A+ TD H+I + DG NL E +D P L INK D Sbjct: 302 SSANFSTDLHSIGQYIQDGRRNLFETVIKVDKPRHNL--TINKED 344
>sp|Q9ZCZ8|IF2_RICPR Translation initiation factor IF-2 Length = 831 Score = 32.0 bits (71), Expect = 1.7 Identities = 31/97 (31%), Positives = 48/97 (49%), Gaps = 11/97 (11%) Frame = +1 Query: 325 LNEEKNSLEIEKLENIAETALRALAIL---GPQTKVSDCNTI-----LSSTNQKFNCR-- 474 LN+E+NSL+ +++ E R L+IL Q+K+ D I L+S NQ N + Sbjct: 58 LNKERNSLDQSVIDSNKEEFNRRLSILKKAAEQSKLHDPAQISTLSKLASINQSINSKNE 117 Query: 475 QLIQFAEMEGLIRKVNGHPINI-ADIVTDKHTIPSQL 582 Q I +E + + + + I A IV D I SQ+ Sbjct: 118 QSITDKAVEQKHQNIEDNKVEIAAKIVQDNENISSQI 154
>sp|Q7VJ31|PROB_HELHP Glutamate 5-kinase (Gamma-glutamyl kinase) (GK) Length = 264 Score = 31.6 bits (70), Expect = 2.2 Identities = 17/46 (36%), Positives = 27/46 (58%) Frame = +1 Query: 463 FNCRQLIQFAEMEGLIRKVNGHPINIADIVTDKHTIPSQLLDGTHN 600 F + LI ++++G K N H + A I+ H+IPSQ L+ TH+ Sbjct: 155 FGAKLLIILSDIDGYFDK-NPHQYDDAQILPIVHSIPSQALEQTHS 199
>sp|O67699|YI45_AQUAE Hypothetical protein AQ_1845 Length = 230 Score = 31.6 bits (70), Expect = 2.2 Identities = 16/41 (39%), Positives = 27/41 (65%) Frame = +1 Query: 100 QRLLPLLNGESSVWDIAQKSQVDVKVVRACVQNLGYVGAIK 222 +++L L+NGE++V DI +KS +D V + L +GAI+ Sbjct: 163 RKVLELVNGENTVKDILEKSGLDKLTVYRTLYGLLAIGAIR 203
>sp|Q9H9C1|CN133_HUMAN Protein C14orf133 Length = 493 Score = 31.2 bits (69), Expect = 2.8 Identities = 22/88 (25%), Positives = 44/88 (50%), Gaps = 1/88 (1%) Frame = +1 Query: 124 GESSVWDIAQKSQVDVKVVRACVQNLGYVGAIKTV-APFRLGSIYMCMPKLIRSWRDSEL 300 G V +I K+ V++++ YV ++ V L + + C +I ++RD + Sbjct: 406 GFHRVVEILHKNNAPVQILQE------YVNLVEDVDTKLNLATKFKCHDVVIDTYRDLKD 459 Query: 301 RRKLLEYVLNEEKNSLEIEKLENIAETA 384 R++LL Y +K S E EK++ + ++ Sbjct: 460 RQQLLAYRSKVDKGSAEEEKIDALLSSS 487
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 82,860,633 Number of Sequences: 369166 Number of extensions: 1621760 Number of successful extensions: 4141 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 4045 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4136 length of database: 68,354,980 effective HSP length: 107 effective length of database: 48,588,335 effective search space used: 6219306880 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)