Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_018_C18
(709 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9WUE4|TUSC4_MOUSE Tumor suppressor candidate 4 (NPR2-li... 86 1e-16
sp|Q8WTW4|TUSC4_HUMAN Tumor suppressor candidate 4 (NPR2-li... 85 2e-16
sp|Q63226|GRID2_RAT Glutamate receptor delta-2 subunit prec... 37 0.067
sp|O43424|GRID2_HUMAN Glutamate receptor delta-2 subunit pr... 36 0.088
sp|P39923|NPR2_YEAST Nitrogen permease regulator 2 35 0.15
sp|Q8Y4R7|G6PI_LISMO Glucose-6-phosphate isomerase (GPI) (P... 33 0.97
sp|Q9ZCZ8|IF2_RICPR Translation initiation factor IF-2 32 1.7
sp|Q7VJ31|PROB_HELHP Glutamate 5-kinase (Gamma-glutamyl kin... 32 2.2
sp|O67699|YI45_AQUAE Hypothetical protein AQ_1845 32 2.2
sp|Q9H9C1|CN133_HUMAN Protein C14orf133 31 2.8
>sp|Q9WUE4|TUSC4_MOUSE Tumor suppressor candidate 4 (NPR2-like) (Gene 21 protein) (G21
protein)
Length = 380
Score = 85.9 bits (211), Expect = 1e-16
Identities = 60/226 (26%), Positives = 108/226 (47%), Gaps = 4/226 (1%)
Frame = +1
Query: 19 EPNVAVECEQVPVLNNDRRII---PLDLTSQRLLPLLNGESSVWDIAQKSQVDVKVVRAC 189
+P VA E + VPV D+ DLT+Q++LP ++G V I+ ++ V++ +VR
Sbjct: 165 DPPVAQEYD-VPVFTKDKEDFFSSQWDLTTQQILPYIDGFRHVQKISAEADVELNLVRIA 223
Query: 190 VQNLGYVGAIKTVAPFRLGSIYMCMPKLIRSWRDSELRRKLLEYVLNEEKNSLEIEKLEN 369
+QNL Y G + V+ + ++Y PK+ D L+ L YV + + +
Sbjct: 224 IQNLLYYGVVTLVSILQYSNVYCPTPKVQDLVDDKSLQEACLSYVTKQGHKRASLRDV-- 281
Query: 370 IAETALRALAILGPQTKVSDCNTILSSTNQKFNCRQLIQFAEMEGLIRKVNGHPINIADI 549
+ L P T V D Q + R+LIQF M+ LIR++ +P+ ++
Sbjct: 282 -----FQLYCSLSPGTTVRDLIGRHPQQLQHVDERKLIQFGLMKNLIRRLQKYPVRVS-- 334
Query: 550 VTDKHTIPSQLLDGTHNLEEIACMLDTPFPQLESEI-NKSDAFVIW 684
++ + P++L G H+ +EI C + +L+ + N + + W
Sbjct: 335 -REERSHPARLYTGCHSYDEICCKTGMSYHELDERLENDPNIIICW 379
>sp|Q8WTW4|TUSC4_HUMAN Tumor suppressor candidate 4 (NPR2-like) (Gene 21 protein) (G21
protein)
Length = 380
Score = 85.1 bits (209), Expect = 2e-16
Identities = 59/226 (26%), Positives = 107/226 (47%), Gaps = 4/226 (1%)
Frame = +1
Query: 19 EPNVAVECEQVPVLNNDRRII---PLDLTSQRLLPLLNGESSVWDIAQKSQVDVKVVRAC 189
+P VA E + VPV D+ DLT+Q++LP ++G + I+ ++ V++ +VR
Sbjct: 165 DPPVAQEYD-VPVFTKDKEDFFNSQWDLTTQQILPYIDGFRHIQKISAEADVELNLVRIA 223
Query: 190 VQNLGYVGAIKTVAPFRLGSIYMCMPKLIRSWRDSELRRKLLEYVLNEEKNSLEIEKLEN 369
+QNL Y G + V+ + ++Y PK+ D L+ L YV + + +
Sbjct: 224 IQNLLYYGVVTLVSILQYSNVYCPTPKVQDLVDDKSLQEACLSYVTKQGHKRASLRDV-- 281
Query: 370 IAETALRALAILGPQTKVSDCNTILSSTNQKFNCRQLIQFAEMEGLIRKVNGHPINIADI 549
+ L P T V D Q + R+LIQF M+ LIR++ +P+ +
Sbjct: 282 -----FQLYCSLSPGTTVRDLIGRHPQQLQHVDERKLIQFGLMKNLIRRLQKYPVR---V 333
Query: 550 VTDKHTIPSQLLDGTHNLEEIACMLDTPFPQLESEI-NKSDAFVIW 684
++ + P++L G H+ +EI C + +L+ + N + + W
Sbjct: 334 TREEQSHPARLYTGCHSYDEICCKTGMSYHELDERLENDPNIIICW 379
>sp|Q63226|GRID2_RAT Glutamate receptor delta-2 subunit precursor (GluR delta-2)
Length = 1007
Score = 36.6 bits (83), Expect = 0.067
Identities = 23/106 (21%), Positives = 44/106 (41%), Gaps = 5/106 (4%)
Frame = +1
Query: 340 NSLEIEKLENIAETALRALAILGPQTKVSDCNTILSSTNQKFNCRQLI-----QFAEMEG 504
+++ IE+L +T RA+ ++ P T S + ++ + F+C +I +++
Sbjct: 213 DTMRIEELNRYRDTLRRAILVMNPATAKSFISEVVETNLVAFDCHWIIINEEINDVDVQE 272
Query: 505 LIRKVNGHPINIADIVTDKHTIPSQLLDGTHNLEEIACMLDTPFPQ 642
L+R+ G I I + G H + C PF Q
Sbjct: 273 LVRRSIGRLTIIRQTFPVPQNISQRCFRGNHRISSTLCDPKDPFAQ 318
>sp|O43424|GRID2_HUMAN Glutamate receptor delta-2 subunit precursor (GluR delta-2)
Length = 1007
Score = 36.2 bits (82), Expect = 0.088
Identities = 23/106 (21%), Positives = 43/106 (40%), Gaps = 5/106 (4%)
Frame = +1
Query: 340 NSLEIEKLENIAETALRALAILGPQTKVSDCNTILSSTNQKFNCRQLI-----QFAEMEG 504
+++ IE+L +T RA+ ++ P T S ++ + F+C +I +++
Sbjct: 213 DTMRIEELNRYRDTLRRAILVMNPATAKSFITEVVETNLVAFDCHWIIINEEINDVDVQE 272
Query: 505 LIRKVNGHPINIADIVTDKHTIPSQLLDGTHNLEEIACMLDTPFPQ 642
L+R+ G I I + G H + C PF Q
Sbjct: 273 LVRRSIGRLTIIRQTFPIPQNISQRCFRGNHRISSTLCDPKDPFAQ 318
>sp|P39923|NPR2_YEAST Nitrogen permease regulator 2
Length = 624
Score = 35.4 bits (80), Expect = 0.15
Identities = 23/81 (28%), Positives = 43/81 (53%), Gaps = 3/81 (3%)
Frame = +1
Query: 22 PNVAVECEQVPVLN-NDRRIIPL--DLTSQRLLPLLNGESSVWDIAQKSQVDVKVVRACV 192
P V E VP+ + N ++II + D T ++P ++G +S+ I++ S D +V C+
Sbjct: 244 PTTCVSLEDVPLSSVNLKKIIDVNWDPTMMSIVPYIDGLNSIAKISKLSNSDPGLVIECI 303
Query: 193 QNLGYVGAIKTVAPFRLGSIY 255
++L Y + F+ +IY
Sbjct: 304 RHLIYYKCVTLSDIFQFSNIY 324
>sp|Q8Y4R7|G6PI_LISMO Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
(PGI) (Phosphohexose isomerase) (PHI)
Length = 450
Score = 32.7 bits (73), Expect = 0.97
Identities = 34/105 (32%), Positives = 44/105 (41%)
Frame = +1
Query: 355 EKLENIAETALRALAILGPQTKVSDCNTILSSTNQKFNCRQLIQFAEMEGLIRKVNGHPI 534
E NIA A +L + KV++ Q FN F E EG +K G
Sbjct: 244 ELKNNIAYQYAAARNVLYRKGKVTELLISYEPGLQYFNEWWKQLFGESEGKDKK--GIYP 301
Query: 535 NIADIVTDKHTIPSQLLDGTHNLEEIACMLDTPFPQLESEINKSD 669
+ A+ TD H+I + DG NL E +D P L INK D
Sbjct: 302 SSANFSTDLHSIGQYIQDGRRNLFETVIKVDKPRHNL--TINKED 344
>sp|Q9ZCZ8|IF2_RICPR Translation initiation factor IF-2
Length = 831
Score = 32.0 bits (71), Expect = 1.7
Identities = 31/97 (31%), Positives = 48/97 (49%), Gaps = 11/97 (11%)
Frame = +1
Query: 325 LNEEKNSLEIEKLENIAETALRALAIL---GPQTKVSDCNTI-----LSSTNQKFNCR-- 474
LN+E+NSL+ +++ E R L+IL Q+K+ D I L+S NQ N +
Sbjct: 58 LNKERNSLDQSVIDSNKEEFNRRLSILKKAAEQSKLHDPAQISTLSKLASINQSINSKNE 117
Query: 475 QLIQFAEMEGLIRKVNGHPINI-ADIVTDKHTIPSQL 582
Q I +E + + + + I A IV D I SQ+
Sbjct: 118 QSITDKAVEQKHQNIEDNKVEIAAKIVQDNENISSQI 154
>sp|Q7VJ31|PROB_HELHP Glutamate 5-kinase (Gamma-glutamyl kinase) (GK)
Length = 264
Score = 31.6 bits (70), Expect = 2.2
Identities = 17/46 (36%), Positives = 27/46 (58%)
Frame = +1
Query: 463 FNCRQLIQFAEMEGLIRKVNGHPINIADIVTDKHTIPSQLLDGTHN 600
F + LI ++++G K N H + A I+ H+IPSQ L+ TH+
Sbjct: 155 FGAKLLIILSDIDGYFDK-NPHQYDDAQILPIVHSIPSQALEQTHS 199
>sp|O67699|YI45_AQUAE Hypothetical protein AQ_1845
Length = 230
Score = 31.6 bits (70), Expect = 2.2
Identities = 16/41 (39%), Positives = 27/41 (65%)
Frame = +1
Query: 100 QRLLPLLNGESSVWDIAQKSQVDVKVVRACVQNLGYVGAIK 222
+++L L+NGE++V DI +KS +D V + L +GAI+
Sbjct: 163 RKVLELVNGENTVKDILEKSGLDKLTVYRTLYGLLAIGAIR 203
>sp|Q9H9C1|CN133_HUMAN Protein C14orf133
Length = 493
Score = 31.2 bits (69), Expect = 2.8
Identities = 22/88 (25%), Positives = 44/88 (50%), Gaps = 1/88 (1%)
Frame = +1
Query: 124 GESSVWDIAQKSQVDVKVVRACVQNLGYVGAIKTV-APFRLGSIYMCMPKLIRSWRDSEL 300
G V +I K+ V++++ YV ++ V L + + C +I ++RD +
Sbjct: 406 GFHRVVEILHKNNAPVQILQE------YVNLVEDVDTKLNLATKFKCHDVVIDTYRDLKD 459
Query: 301 RRKLLEYVLNEEKNSLEIEKLENIAETA 384
R++LL Y +K S E EK++ + ++
Sbjct: 460 RQQLLAYRSKVDKGSAEEEKIDALLSSS 487
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 82,860,633
Number of Sequences: 369166
Number of extensions: 1621760
Number of successful extensions: 4141
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4045
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4136
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 6219306880
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)