Planaria EST Database


DrC_02251

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_02251
         (870 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|P31939|PUR9_HUMAN  Bifunctional purine biosynthesis prote...   155   1e-37
sp|Q9CWJ9|PUR9_MOUSE  Bifunctional purine biosynthesis prote...   155   2e-37
sp|P31335|PUR9_CHICK  Bifunctional purine biosynthesis prote...   152   2e-36
sp|P54113|PUR91_YEAST  Bifunctional purine biosynthesis prot...   135   1e-31
sp|P38009|PUR92_YEAST  Bifunctional purine biosynthesis prot...   132   1e-30
sp|O74928|PUR9_SCHPO  Bifunctional purine biosynthesis prote...   122   1e-27
sp|Q8REV6|PUR9_FUSNN  Bifunctional purine biosynthesis prote...    69   1e-11
sp|Q8XMK2|PUR9_CLOPE  Bifunctional purine biosynthesis prote...    68   3e-11
sp|Q9CFG0|PUR9_LACLA  Bifunctional purine biosynthesis prote...    68   4e-11
sp|P57143|PUR9_BUCAI  Bifunctional purine biosynthesis prote...    67   5e-11
>sp|P31939|PUR9_HUMAN Bifunctional purine biosynthesis protein PURH [Includes:
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (AICAR transformylase); IMP
           cyclohydrolase (Inosinicase) (IMP synthetase) (ATIC)]
          Length = 592

 Score =  155 bits (393), Expect = 1e-37
 Identities = 75/127 (59%), Positives = 96/127 (75%), Gaps = 2/127 (1%)
 Frame = +1

Query: 439 WLRHHTKVLNLKFKSGLKRADINNLIDLYVSGE--SKNDLENFEKGFEVVPEPLTDGERE 612
           WLRHH +VL++KFK+G+KRA+I+N ID YV+G      DL  ++  FE VPE LT+ E++
Sbjct: 466 WLRHHPQVLSMKFKTGVKRAEISNAIDQYVTGTIGEDEDLIKWKALFEEVPELLTEAEKK 525

Query: 613 DWIKKLTNVVLSSDAFFPFRDNIDRAVKSGVKYIAAPSGSTNDASIIEACKEHNVCLIHT 792
           +W++KLT V +SSDAFFPFRDN+DRA +SGV YIAAPSGS  D  +IEAC E  + L HT
Sbjct: 526 EWVEKLTEVSISSDAFFPFRDNVDRAKRSGVAYIAAPSGSAADKVVIEACDELGIILAHT 585

Query: 793 TKRLFHH 813
             RLFHH
Sbjct: 586 NLRLFHH 592
>sp|Q9CWJ9|PUR9_MOUSE Bifunctional purine biosynthesis protein PURH [Includes:
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (AICAR transformylase); IMP
           cyclohydrolase (Inosinicase) (IMP synthetase) (ATIC)]
          Length = 592

 Score =  155 bits (391), Expect = 2e-37
 Identities = 75/127 (59%), Positives = 95/127 (74%), Gaps = 2/127 (1%)
 Frame = +1

Query: 439 WLRHHTKVLNLKFKSGLKRADINNLIDLYVSGE--SKNDLENFEKGFEVVPEPLTDGERE 612
           WLRHH +VL++KFK+G+KRA+I+N ID YV+G      DL  +E  FE VPE LT+ E++
Sbjct: 466 WLRHHPRVLSMKFKAGVKRAEISNAIDQYVTGTIGEGEDLVKWEALFEEVPELLTEAEKK 525

Query: 613 DWIKKLTNVVLSSDAFFPFRDNIDRAVKSGVKYIAAPSGSTNDASIIEACKEHNVCLIHT 792
           +W+ KL+ V +SSDAFFPFRDN+DRA +SGV YI APSGST D  +IEAC E  + L HT
Sbjct: 526 EWVDKLSGVSVSSDAFFPFRDNVDRAKRSGVAYIVAPSGSTADKVVIEACDELGIVLAHT 585

Query: 793 TKRLFHH 813
             RLFHH
Sbjct: 586 DLRLFHH 592
>sp|P31335|PUR9_CHICK Bifunctional purine biosynthesis protein PURH [Includes:
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (AICAR transformylase); IMP
           cyclohydrolase (Inosinicase) (IMP synthetase) (ATIC)]
          Length = 593

 Score =  152 bits (383), Expect = 2e-36
 Identities = 73/127 (57%), Positives = 93/127 (73%), Gaps = 2/127 (1%)
 Frame = +1

Query: 439 WLRHHTKVLNLKFKSGLKRADINNLIDLYVSGE--SKNDLENFEKGFEVVPEPLTDGERE 612
           WLRHH +VL++KFK+G+KRA+++N ID YV+G      DL  ++  FE VP  LT+ E++
Sbjct: 467 WLRHHPRVLSMKFKAGVKRAEVSNAIDQYVTGTIGEDEDLVKWQAMFEEVPAQLTEAEKK 526

Query: 613 DWIKKLTNVVLSSDAFFPFRDNIDRAVKSGVKYIAAPSGSTNDASIIEACKEHNVCLIHT 792
            WI KLT V LSSDAFFPFRDN+DRA + GV++I APSGS  D  +IEAC E  + LIHT
Sbjct: 527 QWIAKLTAVSLSSDAFFPFRDNVDRAKRIGVQFIVAPSGSAADEVVIEACNELGITLIHT 586

Query: 793 TKRLFHH 813
             RLFHH
Sbjct: 587 NLRLFHH 593
>sp|P54113|PUR91_YEAST Bifunctional purine biosynthesis protein ADE16 [Includes:
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (AICAR transformylase); IMP
           cyclohydrolase (Inosinicase) (IMP synthetase) (ATIC)]
          Length = 591

 Score =  135 bits (340), Expect = 1e-31
 Identities = 67/127 (52%), Positives = 86/127 (67%), Gaps = 2/127 (1%)
 Frame = +1

Query: 439 WLRHHTKVLNLKFKSGLKRADINNLIDLYVSGESKNDLE--NFEKGFEVVPEPLTDGERE 612
           WLR H KVLN+K+  G+KRAD +N IDL+V+G+     E  ++E  FE VPEP T  ER 
Sbjct: 465 WLRQHPKVLNMKWAKGIKRADKSNAIDLFVTGQRIEGPEKVDYESKFEEVPEPFTKEERL 524

Query: 613 DWIKKLTNVVLSSDAFFPFRDNIDRAVKSGVKYIAAPSGSTNDASIIEACKEHNVCLIHT 792
           +W+ KL NV LSSDAFFPF DN+ RAV+SGVK+I APSGS  D  + +A    ++  +  
Sbjct: 525 EWLSKLNNVSLSSDAFFPFPDNVYRAVQSGVKFITAPSGSVMDKVVFQAADSFDIVYVEN 584

Query: 793 TKRLFHH 813
             RLFHH
Sbjct: 585 PIRLFHH 591

 Score = 31.6 bits (70), Expect = 3.0
 Identities = 12/18 (66%), Positives = 16/18 (88%)
 Frame = +3

Query: 3   IHCTRLAGNKADNCYVQQ 56
           IHCTRLAG+K DN +++Q
Sbjct: 451 IHCTRLAGDKTDNWWLRQ 468
>sp|P38009|PUR92_YEAST Bifunctional purine biosynthesis protein ADE17 [Includes:
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (AICAR transformylase); IMP
           cyclohydrolase (Inosinicase) (IMP synthetase) (ATIC)]
          Length = 592

 Score =  132 bits (332), Expect = 1e-30
 Identities = 63/128 (49%), Positives = 86/128 (67%), Gaps = 3/128 (2%)
 Frame = +1

Query: 439 WLRHHTKVLNLKFKSGLKRADINNLIDLYVSGE---SKNDLENFEKGFEVVPEPLTDGER 609
           W R H +VL +K+  G+KR + +N IDL+V+G+    + +L  ++  FE +P+P T  ER
Sbjct: 465 WFRQHPRVLEIKWAKGVKRPEKSNAIDLFVTGQIPTEEPELSEYQSKFEEIPKPFTPEER 524

Query: 610 EDWIKKLTNVVLSSDAFFPFRDNIDRAVKSGVKYIAAPSGSTNDASIIEACKEHNVCLIH 789
           ++W+ KLTNV LSSDAFFPF DN+ RAVKSGVKYIAAPSGS  D  +  A    ++  + 
Sbjct: 525 KEWLSKLTNVSLSSDAFFPFPDNVYRAVKSGVKYIAAPSGSVMDKVVFSAADSFDLVYVE 584

Query: 790 TTKRLFHH 813
              RLFHH
Sbjct: 585 NPIRLFHH 592

 Score = 32.3 bits (72), Expect = 1.8
 Identities = 13/18 (72%), Positives = 16/18 (88%)
 Frame = +3

Query: 3   IHCTRLAGNKADNCYVQQ 56
           IHCTRLAG+KADN + +Q
Sbjct: 451 IHCTRLAGDKADNWWFRQ 468
>sp|O74928|PUR9_SCHPO Bifunctional purine biosynthesis protein ade10 [Includes:
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (AICAR transformylase); IMP
           cyclohydrolase (Inosinicase) (IMP synthetase) (ATIC)]
          Length = 585

 Score =  122 bits (306), Expect = 1e-27
 Identities = 61/128 (47%), Positives = 80/128 (62%), Gaps = 3/128 (2%)
 Frame = +1

Query: 439 WLRHHTKVLNLKFKSGLKRADINNLIDLYVSGE---SKNDLENFEKGFEVVPEPLTDGER 609
           WLRHH KVL ++FK   KR + +N IDLYV        ++ E +E  FE +PEPLT  ER
Sbjct: 458 WLRHHPKVLGMQFKKSAKRPEKSNAIDLYVLDAVPAEGSEREQWESAFETIPEPLTKKER 517

Query: 610 EDWIKKLTNVVLSSDAFFPFRDNIDRAVKSGVKYIAAPSGSTNDASIIEACKEHNVCLIH 789
           E+++    +VV +SDAFFPF DNI R  +SGVKY+AAP GS  D ++ +   E N+    
Sbjct: 518 EEFLATCKDVVCASDAFFPFPDNIYRLAQSGVKYVAAPGGSVMDQAVRDTANEFNMVFSE 577

Query: 790 TTKRLFHH 813
              RLFHH
Sbjct: 578 IPLRLFHH 585
>sp|Q8REV6|PUR9_FUSNN Bifunctional purine biosynthesis protein purH [Includes:
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (AICAR transformylase); IMP
           cyclohydrolase (Inosinicase) (IMP synthetase) (ATIC)]
          Length = 504

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 34/61 (55%), Positives = 42/61 (68%)
 Frame = +1

Query: 631 TNVVLSSDAFFPFRDNIDRAVKSGVKYIAAPSGSTNDASIIEACKEHNVCLIHTTKRLFH 810
           T+VVLSSDAFFPF+D I+ A K+GVK I  PSGS ND   IE C  +N+ +I +  R F 
Sbjct: 444 TDVVLSSDAFFPFKDVIELAAKNGVKAIIQPSGSVNDKDSIEECDRNNISMIFSKLRHFK 503

Query: 811 H 813
           H
Sbjct: 504 H 504
>sp|Q8XMK2|PUR9_CLOPE Bifunctional purine biosynthesis protein purH [Includes:
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (AICAR transformylase); IMP
           cyclohydrolase (Inosinicase) (IMP synthetase) (ATIC)]
          Length = 501

 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 31/58 (53%), Positives = 38/58 (65%)
 Frame = +1

Query: 640 VLSSDAFFPFRDNIDRAVKSGVKYIAAPSGSTNDASIIEACKEHNVCLIHTTKRLFHH 813
           VL+SDAFFPFRD +D A K+G+K I  P GS  D   IEAC EH + ++ T  R F H
Sbjct: 444 VLASDAFFPFRDCVDEAAKNGIKAIIQPGGSIRDEESIEACNEHGISMVFTGVRHFKH 501
>sp|Q9CFG0|PUR9_LACLA Bifunctional purine biosynthesis protein purH [Includes:
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (AICAR transformylase); IMP
           cyclohydrolase (Inosinicase) (IMP synthetase) (ATIC)]
          Length = 518

 Score = 67.8 bits (164), Expect = 4e-11
 Identities = 29/60 (48%), Positives = 38/60 (63%)
 Frame = +1

Query: 634 NVVLSSDAFFPFRDNIDRAVKSGVKYIAAPSGSTNDASIIEACKEHNVCLIHTTKRLFHH 813
           N VL SDAFFPF DNID   K+G+K I  P GS  D  +I+AC ++ + ++ T  R F H
Sbjct: 459 NAVLGSDAFFPFADNIDEIAKAGIKAIVQPGGSVRDQEVIDACDKYGIAMVFTGLRHFRH 518
>sp|P57143|PUR9_BUCAI Bifunctional purine biosynthesis protein purH [Includes:
           Phosphoribosylaminoimidazolecarboxamide
           formyltransferase (AICAR transformylase); IMP
           cyclohydrolase (Inosinicase) (IMP synthetase) (ATIC)]
          Length = 525

 Score = 67.4 bits (163), Expect = 5e-11
 Identities = 32/68 (47%), Positives = 39/68 (57%)
 Frame = +1

Query: 610 EDWIKKLTNVVLSSDAFFPFRDNIDRAVKSGVKYIAAPSGSTNDASIIEACKEHNVCLIH 789
           +D  K +    ++SDAFFPFRD ID A   G+  I  P GS  D  II A  EHN+ +I 
Sbjct: 458 KDQGKNIIGATMASDAFFPFRDGIDEAASVGISSIIQPGGSIRDEEIIRAADEHNITMIF 517

Query: 790 TTKRLFHH 813
           T KR F H
Sbjct: 518 TKKRHFKH 525
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 101,786,708
Number of Sequences: 369166
Number of extensions: 2108150
Number of successful extensions: 5899
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5686
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5890
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8598109270
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)