Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_02187 (578 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q05193|DYN1_HUMAN Dynamin-1 38 0.021 sp|P39053|DYN1_MOUSE Dynamin-1 35 0.18 sp|P39052|DYN2_RAT Dynamin-2 33 0.39 sp|P21575|DYN1_RAT Dynamin-1 (D100) (Dynamin, brain) (B-dyn... 33 0.67 sp|P50570|DYN2_HUMAN Dynamin-2 32 1.5 sp|O43516|WASIP_HUMAN Wiskott-Aldrich syndrome protein inte... 31 2.5 sp|P36304|POLR_KYMVJ RNA replicase polyprotein 30 3.3 sp|P27619|DYN_DROME Dynamin (dDyn) (Shibire protein) 30 3.3 sp|Q9JMC1|PI5PA_RAT Phosphatidylinositol 4,5-bisphosphate 5... 30 4.3 sp|P39054|DYN2_MOUSE Dynamin-2 (Dynamin UDNM) 30 4.3
>sp|Q05193|DYN1_HUMAN Dynamin-1 Length = 864 Score = 37.7 bits (86), Expect = 0.021 Identities = 27/98 (27%), Positives = 38/98 (38%), Gaps = 10/98 (10%) Frame = +3 Query: 6 TPVPPPVTNEWISADNSSVGQMXXXXXXXXXXXXXXXXXMK-----LSQGPPTR-----L 155 TP+PPPV + W+ + G+ + + GPP Sbjct: 752 TPMPPPVDDSWLQVQSVPAGRRSPTSSPTPQRRAPAVPPARPGSRGPAPGPPPAGSALGG 811 Query: 156 APSVPKSPNIASNNLIPPLIPQRPSSGGKNTPNIPSRS 269 AP VP P + + PP PQ PS + P +PSRS Sbjct: 812 APPVPSRPGASPDPFGPP--PQVPSRPNRAPPGVPSRS 847
>sp|P39053|DYN1_MOUSE Dynamin-1 Length = 867 Score = 34.7 bits (78), Expect = 0.18 Identities = 26/103 (25%), Positives = 38/103 (36%), Gaps = 10/103 (9%) Frame = +3 Query: 6 TPVPPPVTNEWISADNSSVGQMXXXXXXXXXXXXXXXXXMK-----LSQGPPTR-----L 155 TP+PPPV + W+ + G+ + + GPP Sbjct: 752 TPMPPPVDDSWLQVQSVPAGRRSPTSSPTPQRRAPAVPPARPGSRGPAPGPPPAGSALGG 811 Query: 156 APSVPKSPNIASNNLIPPLIPQRPSSGGKNTPNIPSRS*YEAN 284 AP VP P + + PP PQ PS + P +PS + N Sbjct: 812 APPVPSRPGASPDPFGPP--PQVPSRPNRAPPGVPSLGAWRLN 852
>sp|P39052|DYN2_RAT Dynamin-2 Length = 870 Score = 33.5 bits (75), Expect = 0.39 Identities = 29/104 (27%), Positives = 39/104 (37%), Gaps = 17/104 (16%) Frame = +3 Query: 6 TPVPPPVTNEWISADNSSVGQMXXXXXXXXXXXXXXXXXMKLSQGPP----------TRL 155 TPVPPPV + W+ +S + GPP + Sbjct: 746 TPVPPPVDDTWLQNTSSHSPTPQRRPVSSVHPPGRPPAVRGPTPGPPLIPMPVGATSSFS 805 Query: 156 APSVPKSP---NIASNN---LIPPLIPQRPSSGGKN-TPNIPSR 266 AP +P P N+ +NN PP IP RP+ P +PSR Sbjct: 806 APPIPSRPGPQNVFANNDPFSAPPQIPSRPARIPPGIPPGVPSR 849
>sp|P21575|DYN1_RAT Dynamin-1 (D100) (Dynamin, brain) (B-dynamin) Length = 851 Score = 32.7 bits (73), Expect = 0.67 Identities = 24/95 (25%), Positives = 35/95 (36%), Gaps = 10/95 (10%) Frame = +3 Query: 6 TPVPPPVTNEWISADNSSVGQMXXXXXXXXXXXXXXXXXMK-----LSQGPPTR-----L 155 TP+PPPV + W+ + G+ + + GPP Sbjct: 752 TPMPPPVDDSWLQVQSVPAGRRSPTSSPTPQRRAPAVPPARPGSRGPAPGPPPAGSALGG 811 Query: 156 APSVPKSPNIASNNLIPPLIPQRPSSGGKNTPNIP 260 AP VP P + + PP PQ PS + P +P Sbjct: 812 APPVPSRPGASPDPFGPP--PQVPSRPNRAPPGVP 844
>sp|P50570|DYN2_HUMAN Dynamin-2 Length = 870 Score = 31.6 bits (70), Expect = 1.5 Identities = 25/98 (25%), Positives = 38/98 (38%), Gaps = 13/98 (13%) Frame = +3 Query: 6 TPVPPPVTNEWISADNSSVGQMXXXXXXXXXXXXXXXXXMKLSQGPP----------TRL 155 TPVPPPV + W+ + +S + GPP + Sbjct: 746 TPVPPPVDDTWLQSASSHSPTPQRRPVSSIHPPGRPPAVRGPTPGPPLIPVPVGAAASFS 805 Query: 156 APSVPKSP---NIASNNLIPPLIPQRPSSGGKNTPNIP 260 AP +P P ++ +N+ + P PQ PS + P IP Sbjct: 806 APPIPSRPGPQSVFANSDLFPAPPQIPSRPVRIPPGIP 843
>sp|O43516|WASIP_HUMAN Wiskott-Aldrich syndrome protein interacting protein (WASP interacting protein) (PRPL-2 protein) Length = 503 Score = 30.8 bits (68), Expect = 2.5 Identities = 19/47 (40%), Positives = 24/47 (51%), Gaps = 3/47 (6%) Frame = +3 Query: 132 SQGPPTRLAPSVPKSPNI---ASNNLIPPLIPQRPSSGGKNTPNIPS 263 SQ PP PS P P + +S N P +PQR S +TP +PS Sbjct: 304 SQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPS 350
Score = 30.4 bits (67), Expect = 3.3 Identities = 18/53 (33%), Positives = 25/53 (47%), Gaps = 10/53 (18%) Frame = +3 Query: 141 PPTRLAPSVPKSPNIASNNLI--PPLIPQRP--------SSGGKNTPNIPSRS 269 PP P VP +P ++++ PP P RP SSG TP +P R+ Sbjct: 286 PPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRN 338
>sp|P36304|POLR_KYMVJ RNA replicase polyprotein Length = 1874 Score = 30.4 bits (67), Expect = 3.3 Identities = 21/47 (44%), Positives = 24/47 (51%) Frame = +3 Query: 129 LSQGPPTRLAPSVPKSPNIASNNLIPPLIPQRPSSGGKNTPNIPSRS 269 LSQGP T+ APS +P L PP +P S N PN PS S Sbjct: 637 LSQGPATQ-APSAQPTPG--EPLLAPPTTELKPESSNPNNPN-PSSS 679
>sp|P27619|DYN_DROME Dynamin (dDyn) (Shibire protein) Length = 877 Score = 30.4 bits (67), Expect = 3.3 Identities = 21/84 (25%), Positives = 31/84 (36%), Gaps = 2/84 (2%) Frame = +3 Query: 6 TPVPPPVTNEWISA--DNSSVGQMXXXXXXXXXXXXXXXXXMKLSQGPPTRLAPSVPKSP 179 +P+PPPV N+W+ + DN + ++ GPP + + P Sbjct: 743 SPLPPPVKNDWLPSGLDNPRLS-------------PPSPGGVRGKPGPPAQSSLGGRNPP 789 Query: 180 NIASNNLIPPLIPQRPSSGGKNTP 251 S P IP RP G P Sbjct: 790 LPPSTGRPAPAIPNRPGGGAPPLP 813
>sp|Q9JMC1|PI5PA_RAT Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (Proline-rich inositol polyphosphate 5-phosphatase) Length = 1001 Score = 30.0 bits (66), Expect = 4.3 Identities = 15/42 (35%), Positives = 23/42 (54%) Frame = +3 Query: 144 PTRLAPSVPKSPNIASNNLIPPLIPQRPSSGGKNTPNIPSRS 269 P L+P+ P I SN +PP +P+ P S ++ P+RS Sbjct: 321 PGLLSPTF--RPGIPSNQTVPPPLPKPPRSPSRSPSRSPNRS 360
>sp|P39054|DYN2_MOUSE Dynamin-2 (Dynamin UDNM) Length = 870 Score = 30.0 bits (66), Expect = 4.3 Identities = 27/104 (25%), Positives = 38/104 (36%), Gaps = 17/104 (16%) Frame = +3 Query: 6 TPVPPPVTNEWISADNSSVGQMXXXXXXXXXXXXXXXXXMKLSQGPP----------TRL 155 TPVPPPV + W+ + + GPP + Sbjct: 746 TPVPPPVDDTWLQNTSGHSPTPQRRPVSSVHPPGRPPAVRGPTPGPPLIPMPVGATSSFS 805 Query: 156 APSVPKSP---NIASNN---LIPPLIPQRPSSGGKN-TPNIPSR 266 AP +P P ++ +NN PP IP RP+ P +PSR Sbjct: 806 APPIPSRPGPQSVFANNDPFSAPPQIPSRPARIPPGIPPGVPSR 849
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 56,717,468 Number of Sequences: 369166 Number of extensions: 913616 Number of successful extensions: 2320 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 2169 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 2302 length of database: 68,354,980 effective HSP length: 105 effective length of database: 48,957,805 effective search space used: 4259329035 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)