Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_02135 (716 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P35414|APJ_HUMAN Apelin receptor (G-protein coupled rece... 34 0.45 sp|O97666|APJ_MACMU Apelin receptor (G-protein coupled rece... 34 0.45 sp|Q9WV08|APJ_MOUSE Apelin receptor (G-protein coupled rece... 33 0.76 sp|Q27520|C13A1_CAEEL Putative cytochrome P450 CYP13A1 33 0.76 sp|Q9JHG3|APJ_RAT Apelin receptor (G-protein coupled recept... 32 2.2 sp|P28931|V1A_TAV 1A protein [Includes: Helicase; Methyltra... 31 3.8 sp|Q7WHN0|ISPG_BORBR 4-hydroxy-3-methylbut-2-en-1-yl diphos... 30 4.9 sp|Q7VWL0|ISPG_BORPE 4-hydroxy-3-methylbut-2-en-1-yl diphos... 30 4.9 sp|Q9RXC9|ISPG_DEIRA 4-hydroxy-3-methylbut-2-en-1-yl diphos... 30 4.9 sp|P52170|IMA1_XENLA Importin alpha-1 subunit (Karyopherin ... 30 6.4
>sp|P35414|APJ_HUMAN Apelin receptor (G-protein coupled receptor APJ) (Angiotensin receptor-like 1) (HG11) Length = 380 Score = 33.9 bits (76), Expect = 0.45 Identities = 13/40 (32%), Positives = 22/40 (55%) Frame = +2 Query: 11 LCWCACICIPLIWIIGEIGYWAIV*SLFIRNRFCYCTTVS 130 LCW + ++++G + +W LF+ N F YCT +S Sbjct: 259 LCWMPYHLVKTLYMLGSLLHWPCDFDLFLMNIFPYCTCIS 298
>sp|O97666|APJ_MACMU Apelin receptor (G-protein coupled receptor APJ) (Angiotensin receptor-like 1) Length = 380 Score = 33.9 bits (76), Expect = 0.45 Identities = 13/40 (32%), Positives = 22/40 (55%) Frame = +2 Query: 11 LCWCACICIPLIWIIGEIGYWAIV*SLFIRNRFCYCTTVS 130 LCW + ++++G + +W LF+ N F YCT +S Sbjct: 259 LCWMPYHLVKTLYMLGSLLHWPCDFDLFLMNVFPYCTCIS 298
>sp|Q9WV08|APJ_MOUSE Apelin receptor (G-protein coupled receptor APJ) (Angiotensin receptor-like 1) (MSR) Length = 377 Score = 33.1 bits (74), Expect = 0.76 Identities = 12/40 (30%), Positives = 22/40 (55%) Frame = +2 Query: 11 LCWCACICIPLIWIIGEIGYWAIV*SLFIRNRFCYCTTVS 130 LCW + ++++G + +W +F+ N F YCT +S Sbjct: 257 LCWMPYHLVKTLYMLGSLLHWPCDFDIFLMNVFPYCTCIS 296
>sp|Q27520|C13A1_CAEEL Putative cytochrome P450 CYP13A1 Length = 519 Score = 33.1 bits (74), Expect = 0.76 Identities = 26/121 (21%), Positives = 55/121 (45%), Gaps = 9/121 (7%) Frame = +3 Query: 198 LYSGVQTTDSFNTNSISSNKLNDFIESCL--REENILHFGEFCNDFSKICAVQLAD-KVN 368 +++ ++ + N I + DFI+ L + E++ HFGE DFSK Sbjct: 255 IHNRIKQREEDQKNGIEIGEPADFIDLFLDAKAEDVEHFGENNGDFSKSTTYTNRQLTTE 314 Query: 369 DIIMRCLVYFKSEYPELAAS---SVFLIGC---LMENLQEKQKASLQKGQICVELIQLLR 530 +I+ +C V+ + + A S + +L+ + + LQE+ ++ ++ + L+ Sbjct: 315 EIVGQCTVFLIAGFDTTALSLSYATYLLATHPEIQKKLQEEVNRECPNPEVTIDQLSKLK 374 Query: 531 Y 533 Y Sbjct: 375 Y 375
>sp|Q9JHG3|APJ_RAT Apelin receptor (G-protein coupled receptor APJ) (Angiotensin receptor-like 1) (B78) (GPCR34) Length = 377 Score = 31.6 bits (70), Expect = 2.2 Identities = 12/40 (30%), Positives = 21/40 (52%) Frame = +2 Query: 11 LCWCACICIPLIWIIGEIGYWAIV*SLFIRNRFCYCTTVS 130 LCW + ++++G + +W F+ N F YCT +S Sbjct: 257 LCWMPYHLVKTLYMLGNLLHWPCDFDSFLMNVFPYCTCIS 296
>sp|P28931|V1A_TAV 1A protein [Includes: Helicase; Methyltransferase] Length = 993 Score = 30.8 bits (68), Expect = 3.8 Identities = 26/76 (34%), Positives = 36/76 (47%), Gaps = 6/76 (7%) Frame = +3 Query: 141 DPSTDVIRAC--KVALKQIMPLY----SGVQTTDSFNTNSISSNKLNDFIESCLREENIL 302 +P+TDVI K AL L+ S TT +SI N N+ + E +L Sbjct: 729 NPATDVIVTANKKSALDVRQALFNCTDSKEATTFVRTADSILMNDTNEVQRVLVDEVVLL 788 Query: 303 HFGEFCNDFSKICAVQ 350 HFG+ C SK+ AV+ Sbjct: 789 HFGQLCAVMSKLKAVR 804
>sp|Q7WHN0|ISPG_BORBR 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase) sp|Q7W6P6|ISPG_BORPA 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase) Length = 433 Score = 30.4 bits (67), Expect = 4.9 Identities = 13/57 (22%), Positives = 29/57 (50%) Frame = +3 Query: 318 CNDFSKICAVQLADKVNDIIMRCLVYFKSEYPELAASSVFLIGCLMENLQEKQKASL 488 C S +LAD + + R + +++ YP + + +V ++GC++ E + A + Sbjct: 323 CGRTSSTFFQELADSIQSFLRRQMPLWRTRYPGVESMNVAVMGCVVNGPGESRHADI 379
>sp|Q7VWL0|ISPG_BORPE 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase) Length = 431 Score = 30.4 bits (67), Expect = 4.9 Identities = 13/57 (22%), Positives = 29/57 (50%) Frame = +3 Query: 318 CNDFSKICAVQLADKVNDIIMRCLVYFKSEYPELAASSVFLIGCLMENLQEKQKASL 488 C S +LAD + + R + +++ YP + + +V ++GC++ E + A + Sbjct: 323 CGRTSSTFFQELADSIQSFLRRQMPLWRTRYPGVESMNVAVMGCVVNGPGESRHADI 379
>sp|Q9RXC9|ISPG_DEIRA 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase) Length = 429 Score = 30.4 bits (67), Expect = 4.9 Identities = 13/46 (28%), Positives = 26/46 (56%) Frame = +3 Query: 351 LADKVNDIIMRCLVYFKSEYPELAASSVFLIGCLMENLQEKQKASL 488 LA K+ D I + +K++YP + V ++GC++ E + A++ Sbjct: 331 LAQKIQDFIRESMPEWKAKYPGVEDMQVAVMGCVVNGPGESKHANI 376
>sp|P52170|IMA1_XENLA Importin alpha-1 subunit (Karyopherin alpha-1 subunit) Length = 522 Score = 30.0 bits (66), Expect = 6.4 Identities = 19/68 (27%), Positives = 36/68 (52%) Frame = +3 Query: 372 IIMRCLVYFKSEYPELAASSVFLIGCLMENLQEKQKASLQKGQICVELIQLLRYKNPKVR 551 I+ R + S + S+ +G ++ ++ +A++ G + V L QLLR++ P ++ Sbjct: 287 IVDRLIQLMYSPELSIVTPSLRTVGNIVTGTDKQTQAAIDAGVLSV-LPQLLRHQKPSIQ 345 Query: 552 ARAAEAIS 575 AA AIS Sbjct: 346 KEAAWAIS 353
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 69,397,573 Number of Sequences: 369166 Number of extensions: 1178336 Number of successful extensions: 3083 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 3011 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3082 length of database: 68,354,980 effective HSP length: 107 effective length of database: 48,588,335 effective search space used: 6365071885 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)