Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_02109 (626 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q9H9Q2|CSN7B_HUMAN COP9 signalosome complex subunit 7b (... 96 1e-19 sp|Q8BV13|CSN7B_MOUSE COP9 signalosome complex subunit 7b (... 95 1e-19 sp|Q9CZ04|CSN7A_MOUSE COP9 signalosome complex subunit 7a (... 89 7e-18 sp|Q9UBW8|CSN7A_HUMAN COP9 signalosome complex subunit 7a (... 87 5e-17 sp|Q9V4S8|CSN7_DROME COP9 signalosome complex subunit 7 (Si... 84 4e-16 sp|Q94JU3|CSN7_ARATH COP9 signalosome complex subunit 7 (CS... 83 7e-16 sp|Q94261|CSN7_CAEEL Probable COP9 signalosome complex subu... 40 0.006 sp|Q09722|CSN7B_SCHPO COP9 signalosome complex subunit 7B 36 0.092 sp|O95613|PCNT_HUMAN Pericentrin (Pericentrin B) (Kendrin) 36 0.092 sp|P03879|MBI4_YEAST Intron-encoded RNA maturase bI4 precur... 33 0.60
>sp|Q9H9Q2|CSN7B_HUMAN COP9 signalosome complex subunit 7b (Signalosome subunit 7b) (SGN7b) (JAB1-containing signalosome subunit 7b) Length = 264 Score = 95.5 bits (236), Expect = 1e-19 Identities = 46/154 (29%), Positives = 83/154 (53%) Frame = +3 Query: 3 INLFCYGTYKEYIENQDCYPKLCDEQLRKLKQLTIITLSMTNGVLYYKIIYDAIDETCQR 182 +NLF YGTY +YI N++ P+L Q KLK LTI++L+ + Y ++ ++ R Sbjct: 67 LNLFAYGTYPDYIANKESLPELSTAQQNKLKHLTIVSLASRMKCIPYSVLLKDLEMRNLR 126 Query: 183 KIEELILDLIYYNILEGYFDQENECFQVESTSGRDFPIEQIDEMKSKLIEWAKKCDSVIE 362 ++E+LI++ +Y +I++G DQ N+ +V+ GRD + I+ + L EW C++V+ Sbjct: 127 ELEDLIIEAVYTDIIQGKLDQRNQLLEVDFCIGRDIRKKDINNIVKTLHEWCDGCEAVLL 186 Query: 363 RLAHEFSAANNIKAQRRIEHQQASINLEKAREEI 464 + + AN K QQ + ++ + Sbjct: 187 GIEQQVLRANQYKENHNRTQQQVEAEVTNIKKTL 220
>sp|Q8BV13|CSN7B_MOUSE COP9 signalosome complex subunit 7b (Signalosome subunit 7b) (SGN7b) (JAB1-containing signalosome subunit 7b) Length = 264 Score = 95.1 bits (235), Expect = 1e-19 Identities = 46/154 (29%), Positives = 83/154 (53%) Frame = +3 Query: 3 INLFCYGTYKEYIENQDCYPKLCDEQLRKLKQLTIITLSMTNGVLYYKIIYDAIDETCQR 182 +NLF YGTY +YI N++ P+L Q KLK LTI++L+ + Y ++ ++ R Sbjct: 67 LNLFAYGTYPDYIANKESLPELSVAQQNKLKHLTIVSLASRMKCIPYSVLLKDLEMRNLR 126 Query: 183 KIEELILDLIYYNILEGYFDQENECFQVESTSGRDFPIEQIDEMKSKLIEWAKKCDSVIE 362 ++E+LI++ +Y +I++G DQ N+ +V+ GRD + I+ + L EW C++V+ Sbjct: 127 ELEDLIIEAVYTDIIQGKLDQRNQLLEVDFCIGRDIRKKDINNIVKTLHEWCDGCEAVLL 186 Query: 363 RLAHEFSAANNIKAQRRIEHQQASINLEKAREEI 464 + + AN K QQ + ++ + Sbjct: 187 GIEQQVLRANQYKENHHRTQQQVEAEVSNIKKTL 220
>sp|Q9CZ04|CSN7A_MOUSE COP9 signalosome complex subunit 7a (Signalosome subunit 7a) (SGN7a) (JAB1-containing signalosome subunit 7a) Length = 275 Score = 89.4 bits (220), Expect = 7e-18 Identities = 48/185 (25%), Positives = 94/185 (50%), Gaps = 3/185 (1%) Frame = +3 Query: 3 INLFCYGTYKEYIENQDCYPKLCDEQLRKLKQLTIITLSMTNGVLYYKIIYDAIDETCQR 182 + +F YGTY +Y+ P L D Q KL+ L+++TL+ + Y ++ +A+ R Sbjct: 67 LTVFAYGTYADYLAEARNLPPLTDAQKNKLRHLSVVTLAAKVKCIPYAVLLEALALRNVR 126 Query: 183 KIEELILDLIYYNILEGYFDQENECFQVESTSGRDFPIEQIDEMKSKLIEWAKKCDSVIE 362 ++E+L+++ +Y ++L G DQ N+ +V+ + GRD + + + L EW C+ V+ Sbjct: 127 QLEDLVIEAVYADVLRGSLDQRNQRLEVDYSIGRDIQRQDLSAIAQTLQEWCVGCEVVLS 186 Query: 363 RLAHEFSAANNIKAQRRIEHQQAS---INLEKAREEISQVIRKETSGQSFDNVTPIKDSS 533 + + S AN K Q+ QQ NL+K + + TS ++T +++ + Sbjct: 187 GIEEQVSRANQHKEQQLGLKQQIESEVANLKKTIKVTTAAAAAATSQDPEQHLTELREPA 246 Query: 534 AACQE 548 + + Sbjct: 247 SGTNQ 251
>sp|Q9UBW8|CSN7A_HUMAN COP9 signalosome complex subunit 7a (Signalosome subunit 7a) (SGN7a) (JAB1-containing signalosome subunit 7a) (Dermal papilla derived protein 10) sp|Q5R762|CSN7A_PONPY COP9 signalosome complex subunit 7a (Signalosome subunit 7a) (SGN7a) (JAB1-containing signalosome subunit 7a) Length = 275 Score = 86.7 bits (213), Expect = 5e-17 Identities = 47/178 (26%), Positives = 91/178 (51%), Gaps = 3/178 (1%) Frame = +3 Query: 3 INLFCYGTYKEYIENQDCYPKLCDEQLRKLKQLTIITLSMTNGVLYYKIIYDAIDETCQR 182 + +F YGTY +Y+ P L + Q KL+ L+++TL+ + Y ++ +A+ R Sbjct: 67 LTVFAYGTYADYLAEARNLPPLTEAQKNKLRHLSVVTLAAKVKCIPYAVLLEALALRNVR 126 Query: 183 KIEELILDLIYYNILEGYFDQENECFQVESTSGRDFPIEQIDEMKSKLIEWAKKCDSVIE 362 ++E+L+++ +Y ++L G DQ N+ +V+ + GRD + + + L EW C+ V+ Sbjct: 127 QLEDLVIEAVYADVLRGSLDQRNQRLEVDYSIGRDIQRQDLSAIARTLQEWCVGCEVVLS 186 Query: 363 RLAHEFSAANNIKAQRRIEHQQAS---INLEKAREEISQVIRKETSGQSFDNVTPIKD 527 + + S AN K Q+ QQ NL+K + + TS ++T +++ Sbjct: 187 GIEEQVSRANQHKEQQLGLKQQIESEVANLKKTIKVTTAAAAAATSQDPEQHLTELRE 244
>sp|Q9V4S8|CSN7_DROME COP9 signalosome complex subunit 7 (Signalosome subunit 7) (Dch7) Length = 278 Score = 83.6 bits (205), Expect = 4e-16 Identities = 46/163 (28%), Positives = 85/163 (52%) Frame = +3 Query: 3 INLFCYGTYKEYIENQDCYPKLCDEQLRKLKQLTIITLSMTNGVLYYKIIYDAIDETCQR 182 +NLF YGTYKEY + + +L +KL+ LTI++L++ + Y ++ ++ R Sbjct: 75 LNLFAYGTYKEYRAQPEKFIELTPAMQKKLQHLTIVSLAIKAKSIPYALLLSELEIDNVR 134 Query: 183 KIEELILDLIYYNILEGYFDQENECFQVESTSGRDFPIEQIDEMKSKLIEWAKKCDSVIE 362 +E++I++ IY +I+ G Q +V+ GRD P ++ L W CDSV Sbjct: 135 HLEDIIIEAIYADIIHGKLFQNTRILEVDYAQGRDIPPGYTGQIVETLQAWVNSCDSVSN 194 Query: 363 RLAHEFSAANNIKAQRRIEHQQASINLEKAREEISQVIRKETS 491 + + AN K++R I ++ +E+ + +V++ +TS Sbjct: 195 CIEMQIKYANAEKSKRLINKER----VEQDLINLKKVLKSQTS 233
>sp|Q94JU3|CSN7_ARATH COP9 signalosome complex subunit 7 (CSN complex subunit 7) (FUSCA protein 5) (FUSCA5) Length = 260 Score = 82.8 bits (203), Expect = 7e-16 Identities = 46/156 (29%), Positives = 84/156 (53%), Gaps = 1/156 (0%) Frame = +3 Query: 3 INLFCYGTYKEYIENQDCYPKLCDEQLRKLKQLTIITLSMTNGVLYYKIIYDAIDETCQR 182 + LF +GT+ +Y N P L +Q+ KLKQLT++TL+ +N VL Y + +D + R Sbjct: 66 LRLFAHGTWGDYKCNATRLPHLSPDQILKLKQLTVLTLAESNKVLPYDTLMVELDVSNVR 125 Query: 183 KIEE-LILDLIYYNILEGYFDQENECFQVESTSGRDFPIEQIDEMKSKLIEWAKKCDSVI 359 ++E+ LI + +Y I+ G DQ CF+V +GRD Q+ M L W ++++ Sbjct: 126 ELEDFLINECMYAGIVRGKLDQLKRCFEVPFAAGRDLRPGQLGNMLHTLSNWLNTSENLL 185 Query: 360 ERLAHEFSAANNIKAQRRIEHQQASINLEKAREEIS 467 + + A+N+ + ++A +E+ ++ +S Sbjct: 186 ISIQDKIKWADNMSEMDKKHRKEAEEGVEEVKKSLS 221
>sp|Q94261|CSN7_CAEEL Probable COP9 signalosome complex subunit 7 (Signalosome subunit 7) Length = 390 Score = 39.7 bits (91), Expect = 0.006 Identities = 28/108 (25%), Positives = 46/108 (42%), Gaps = 8/108 (7%) Frame = +3 Query: 3 INLFCYGTYKEYIENQDCYPKLCDEQ--------LRKLKQLTIITLSMTNGVLYYKIIYD 158 + LF GT K+Y E PK E L+K++ LT+++L+ + + Sbjct: 251 LELFISGTLKDYKEFVAKNPKFVTEHLKVDETILLKKIRLLTLMSLAEEKNEISLDELAK 310 Query: 159 AIDETCQRKIEELILDLIYYNILEGYFDQENECFQVESTSGRDFPIEQ 302 +D +EE ++D I N + G ++ V S R F EQ Sbjct: 311 QLDILADETLEEFVIDAIQVNAISGKINEMARTLIVSSYQHRRFGTEQ 358
>sp|Q09722|CSN7B_SCHPO COP9 signalosome complex subunit 7B Length = 402 Score = 35.8 bits (81), Expect = 0.092 Identities = 30/118 (25%), Positives = 55/118 (46%), Gaps = 5/118 (4%) Frame = +3 Query: 72 DEQLRKLKQLTIITLSMT--NGVLYYKIIYDAIDETCQRKIEELILDLIYYNILEGYFDQ 245 D RK+K LTI +L+ N L Y + ++ + + ++E I+D+I ++EG Q Sbjct: 277 DAIARKMKLLTIASLATQAPNNTLSYGDVAKSL-KIDENEVELWIIDVIRAGLVEGRMSQ 335 Query: 246 ENECFQVESTSGRDFPIEQIDEMKSKLIEWAKKCD---SVIERLAHEFSAANNIKAQR 410 + + +S R F + + KL +W V+E+ F+ A++ K R Sbjct: 336 LTKTLSIHRSSYRVFGKHEWVALHEKLAKWGSSLRYMLQVMEQPLSSFTIASSKKGNR 393
>sp|O95613|PCNT_HUMAN Pericentrin (Pericentrin B) (Kendrin) Length = 3336 Score = 35.8 bits (81), Expect = 0.092 Identities = 30/143 (20%), Positives = 67/143 (46%), Gaps = 1/143 (0%) Frame = +3 Query: 48 QDCYPKLCDEQLRKLKQLTIITLSMTNGVLYYKIIYDAIDETCQRKIEELILDLIYYNIL 227 +D LC+ + +K +QL+ + VL + + + + + ++EL + L Sbjct: 2607 RDLKSDLCESR-QKSEQLSRSLCEVQQEVLQLRSMLSSKENELKAALQELESEQGKGRAL 2665 Query: 228 EGYFDQEN-ECFQVESTSGRDFPIEQIDEMKSKLIEWAKKCDSVIERLAHEFSAANNIKA 404 + ++E Q ES S + ++E+++ L + + L HE +A +N++ Sbjct: 2666 QSQLEEEQLRHLQRESQSAK-----ALEELRASLETQRAQSSRLCVALKHEQTAKDNLQK 2720 Query: 405 QRRIEHQQASINLEKAREEISQV 473 + RIEH + L + R ++S++ Sbjct: 2721 ELRIEHSRCEALLAQERSQLSEL 2743
>sp|P03879|MBI4_YEAST Intron-encoded RNA maturase bI4 precursor (RNA maturase SCbI4) [Contains: Truncated, nonfunctional cytochrome b; RNA maturase bI4 ] Length = 638 Score = 33.1 bits (74), Expect = 0.60 Identities = 15/39 (38%), Positives = 24/39 (61%) Frame = -3 Query: 282 YRWSIQLESIHSLDQNILRECYSKSNLKSILLFFVDKFH 166 ++WSI + +H++ + C SKSN K LF +DKF+ Sbjct: 571 FKWSINNKELHNIFYTYNKSCPSKSN-KGKRLFLIDKFY 608
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 62,534,251 Number of Sequences: 369166 Number of extensions: 1182647 Number of successful extensions: 4681 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 4415 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4676 length of database: 68,354,980 effective HSP length: 106 effective length of database: 48,773,070 effective search space used: 4974853140 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)