Planaria EST Database


DrC_02069

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_02069
         (818 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q9C0J8|WDR33_HUMAN  WD-repeat protein 33 (WD-repeat prote...   227   3e-59
sp|Q9UTN4|YAGE_SCHPO  Hypothetical WD-repeat protein C12G12....   149   7e-36
sp|P42841|YN57_YEAST  Hypothetical 53.1 kDa Trp-Asp repeats ...   112   1e-24
sp|O43017|SWD3_SCHPO  Set1 complex component swd3 (Set1C com...    49   2e-05
sp|P49695|PKWA_THECU  Probable serine/threonine-protein kina...    48   3e-05
sp|P56093|TUP1_CANAL  Transcriptional repressor TUP1               45   2e-04
sp|O88342|WDR1_MOUSE  WD-repeat protein 1 (Actin-interacting...    45   2e-04
sp|P25382|YCW2_YEAST  Hypothetical WD-repeat protein YCR072C       45   3e-04
sp|P38262|SIF2_YEAST  SIR4-interacting protein SIF2                44   7e-04
sp|O75083|WDR1_HUMAN  WD-repeat protein 1 (Actin interacting...    43   0.001
>sp|Q9C0J8|WDR33_HUMAN WD-repeat protein 33 (WD-repeat protein WDC146)
          Length = 1336

 Score =  227 bits (578), Expect = 3e-59
 Identities = 104/162 (64%), Positives = 128/162 (79%)
 Frame = +2

Query: 236 GKRMRKAVFRRTIDYNSSVALFIEQRTWKRRFSSRCAIQPDIMYQHLLTPPTDYRDNPMN 415
           GKRMRKAV R+TIDYN SV  ++E R W+R      AIQPD  Y + L PP    +NPMN
Sbjct: 45  GKRMRKAVNRKTIDYNPSVIKYLENRIWQRDQRDMRAIQPDAGYYNDLVPPIGMLNNPMN 104

Query: 416 CVCAKHVRTSTNKNKCPIYAVCWTPDGRRLITGASSGEFTLWNGLTFNFETILQAHDTHI 595
            V  K VRTSTNK KCP++ V WTP+GRRL+TGASSGEFTLWNGLTFNFETILQAHD+ +
Sbjct: 105 AVTTKFVRTSTNKVKCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPV 164

Query: 596 RAMKWSNNEEWLVSADDSGFVKYWQANMNDVNVFQAHKDSVR 721
           RAM WS+N+ W+++AD  G+VKYWQ+NMN+V +FQAHK+++R
Sbjct: 165 RAMTWSHNDMWMLTADHGGYVKYWQSNMNNVKMFQAHKEAIR 206

 Score = 32.7 bits (73), Expect = 1.2
 Identities = 20/94 (21%), Positives = 38/94 (40%), Gaps = 4/94 (4%)
 Frame = +2

Query: 467 IYAVCWTPDGRRLITGASSGE--FTLWNGLTFNFETILQAHDTHIRAMKWSNNEEWLVSA 640
           +  V W P    +++G+   +     W+  T      L AH   +  +K + N  WL++A
Sbjct: 247 VKCVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKLNLNGNWLLTA 306

Query: 641 DDSGFVKYWQAN--MNDVNVFQAHKDSVRGVRYY 736
                 K +       ++ VF+ HK     V ++
Sbjct: 307 SRDHLCKLFDIRNLKEELQVFRGHKKEATAVAWH 340
>sp|Q9UTN4|YAGE_SCHPO Hypothetical WD-repeat protein C12G12.14c in chromosome I
          Length = 509

 Score =  149 bits (377), Expect = 7e-36
 Identities = 72/163 (44%), Positives = 104/163 (63%)
 Frame = +2

Query: 245 MRKAVFRRTIDYNSSVALFIEQRTWKRRFSSRCAIQPDIMYQHLLTPPTDYRDNPMNCVC 424
           ++K + RRT+DY S ++ +I  R  +         +P+      L PP +Y+ N  + +C
Sbjct: 10  IQKPMTRRTVDYGSGLSKYIVNRHLRSNRYHIHVPRPNPNQIINLYPPYEYKYNNTSSLC 69

Query: 425 AKHVRTSTNKNKCPIYAVCWTPDGRRLITGASSGEFTLWNGLTFNFETILQAHDTHIRAM 604
            K++ TS NK +  I  V WTPDGRRL+TG+S+GEFTLWNGLTFNFE I Q+HD  +R  
Sbjct: 70  TKYIHTSANKARHVINVVRWTPDGRRLLTGSSTGEFTLWNGLTFNFELINQSHDYAVRCA 129

Query: 605 KWSNNEEWLVSADDSGFVKYWQANMNDVNVFQAHKDSVRGVRY 733
           +WS +  WL+S D  G VKY++ N+N+V + QAH+  VR V +
Sbjct: 130 EWSTDGRWLISGDGGGMVKYFEPNLNNVKIVQAHEMEVRDVAF 172
>sp|P42841|YN57_YEAST Hypothetical 53.1 kDa Trp-Asp repeats containing protein in
           HXT14-PHA2 intergenic region
          Length = 465

 Score =  112 bits (280), Expect = 1e-24
 Identities = 59/160 (36%), Positives = 94/160 (58%), Gaps = 3/160 (1%)
 Frame = +2

Query: 263 RRTIDYNSSVALFIEQRTWKRRFSSRCAIQPDIMYQHLLTPPTDYR--DNPMNCVCAKHV 436
           RR++D +S    +I     +R       ++P+  Y   + PP  YR  D  +N + +K  
Sbjct: 30  RRSVDVSSP---YINLYYNRRHGLPNLVVEPETSYTIDIMPPNAYRGRDRVIN-LPSKFT 85

Query: 437 RTSTNKNKCPIYAVCWTPDGRRLITGASSGEFTLWNGLTFNFETILQAHDTHIRAMKWSN 616
             S+NK K  I A+ WTP+GRRL+    SGEF+LWN  +F FET++QAHD+ +  MK+S+
Sbjct: 86  HLSSNKVKHVIPAIQWTPEGRRLVVATYSGEFSLWNASSFTFETLMQAHDSAVTTMKYSH 145

Query: 617 NEEWLVSADDSGFVKYWQANMNDV-NVFQAHKDSVRGVRY 733
           + +W++S D  G +K WQ N + V  +  AH +S+R + +
Sbjct: 146 DSDWMISGDADGMIKIWQPNFSMVKEIDAAHTESIRDMAF 185
>sp|O43017|SWD3_SCHPO Set1 complex component swd3 (Set1C component swd3) (COMPASS
           component swd3) (Complex proteins associated with set1
           protein swd3)
          Length = 380

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 24/90 (26%), Positives = 41/90 (45%), Gaps = 1/90 (1%)
 Frame = +2

Query: 467 IYAVCWTPDGRRLITGASSGEFTLWNGLTFNFETILQAHDTHIRAMKWSNNEEWLVSADD 646
           +  V  +P+ R + T +S G   +W+ LTF  E  L  H   I  +KW+   ++L SA D
Sbjct: 57  VTCVSVSPNKRWIATSSSDGTIKIWSALTFRLECTLFGHYRGISQVKWATGSKYLASASD 116

Query: 647 SGFVKYWQANMN-DVNVFQAHKDSVRGVRY 733
              ++ W       V   + H + V  + +
Sbjct: 117 DKTIRIWDFEKRCSVRCLKGHTNYVSSIDF 146
>sp|P49695|PKWA_THECU Probable serine/threonine-protein kinase pkwA
          Length = 742

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 26/89 (29%), Positives = 46/89 (51%)
 Frame = +2

Query: 467 IYAVCWTPDGRRLITGASSGEFTLWNGLTFNFETILQAHDTHIRAMKWSNNEEWLVSADD 646
           +YAV ++PDG  + +G+  G   LW+  T     +LQA   ++ ++ +S +   LV   D
Sbjct: 588 VYAVAFSPDGSMVASGSRDGTIRLWDVATGKERDVLQAPAENVVSLAFSPDGSMLVHGSD 647

Query: 647 SGFVKYWQANMNDVNVFQAHKDSVRGVRY 733
           S    +  A+   ++ F+ H D VR V +
Sbjct: 648 STVHLWDVASGEALHTFEGHTDWVRAVAF 676

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 21/82 (25%), Positives = 41/82 (50%), Gaps = 1/82 (1%)
 Frame = +2

Query: 476 VCWTPDGRRLITGASSGEFTLWNGLTFNFETILQAHDTHIRAMKWSNNEEWLVSADDSGF 655
           + ++PDG  + +G+  G   LWN  T     +L+ H  ++ A+ +S +   + S    G 
Sbjct: 549 IAFSPDGSMVASGSRDGTARLWNVATGTEHAVLKGHTDYVYAVAFSPDGSMVASGSRDGT 608

Query: 656 VKYWQ-ANMNDVNVFQAHKDSV 718
           ++ W  A   + +V QA  ++V
Sbjct: 609 IRLWDVATGKERDVLQAPAENV 630

 Score = 37.0 bits (84), Expect = 0.065
 Identities = 17/67 (25%), Positives = 31/67 (46%)
 Frame = +2

Query: 467 IYAVCWTPDGRRLITGASSGEFTLWNGLTFNFETILQAHDTHIRAMKWSNNEEWLVSADD 646
           + AV ++PDG  L +G+      LW+       T L+ H   + ++ +      L SA +
Sbjct: 671 VRAVAFSPDGALLASGSDDRTIRLWDVAAQEEHTTLEGHTEPVHSVAFHPEGTTLASASE 730

Query: 647 SGFVKYW 667
            G ++ W
Sbjct: 731 DGTIRIW 737

 Score = 36.6 bits (83), Expect = 0.085
 Identities = 20/90 (22%), Positives = 38/90 (42%), Gaps = 1/90 (1%)
 Frame = +2

Query: 467 IYAVCWTPDGRRLITGASSGEFTLWNGLTFNFETILQAHDTHIRAMKWSNNEEWLVSADD 646
           + AV ++PDG  L +G+      LW+        + + H  ++  + +S +   + S   
Sbjct: 504 VRAVAFSPDGALLASGSDDATVRLWDVAAAEERAVFEGHTHYVLDIAFSPDGSMVASGSR 563

Query: 647 SGFVKYWQ-ANMNDVNVFQAHKDSVRGVRY 733
            G  + W  A   +  V + H D V  V +
Sbjct: 564 DGTARLWNVATGTEHAVLKGHTDYVYAVAF 593

 Score = 34.7 bits (78), Expect = 0.32
 Identities = 20/91 (21%), Positives = 41/91 (45%), Gaps = 1/91 (1%)
 Frame = +2

Query: 467 IYAVCWTPDGRRLITGASSGEFTLWNGLTFNFETILQAHDTHIRAMKWSNNEEWLVSADD 646
           + ++ ++PDG  L+ G+ S    LW+  +       + H   +RA+ +S +   L S  D
Sbjct: 630 VVSLAFSPDGSMLVHGSDS-TVHLWDVASGEALHTFEGHTDWVRAVAFSPDGALLASGSD 688

Query: 647 SGFVKYWQ-ANMNDVNVFQAHKDSVRGVRYY 736
              ++ W  A   +    + H + V  V ++
Sbjct: 689 DRTIRLWDVAAQEEHTTLEGHTEPVHSVAFH 719

 Score = 33.9 bits (76), Expect = 0.55
 Identities = 22/88 (25%), Positives = 39/88 (44%), Gaps = 1/88 (1%)
 Frame = +2

Query: 473 AVCWTPDGRRLITGASSGEFTLWNGLTFNFETILQAHDTHIRAMKWSNNEEWLVSADDSG 652
           AV ++P G  L  G+      +W+  + +    L+ H   +RA+ +S +   L S  D  
Sbjct: 464 AVAFSPGGSLLAGGSGDKLIHVWDVASGDELHTLEGHTDWVRAVAFSPDGALLASGSDDA 523

Query: 653 FVKYWQ-ANMNDVNVFQAHKDSVRGVRY 733
            V+ W  A   +  VF+ H   V  + +
Sbjct: 524 TVRLWDVAAAEERAVFEGHTHYVLDIAF 551
>sp|P56093|TUP1_CANAL Transcriptional repressor TUP1
          Length = 514

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 30/110 (27%), Positives = 52/110 (47%), Gaps = 9/110 (8%)
 Frame = +2

Query: 425 AKHVRTSTNKNKCP---------IYAVCWTPDGRRLITGASSGEFTLWNGLTFNFETILQ 577
           AK +  S+N+NK           I +VC++PDG+ L TGA      +W+  T     IL+
Sbjct: 237 AKLIDESSNENKDDNTTASGDLYIRSVCFSPDGKLLATGAEDKLIRIWDLSTKRIIKILR 296

Query: 578 AHDTHIRAMKWSNNEEWLVSADDSGFVKYWQANMNDVNVFQAHKDSVRGV 727
            H+  I ++ +  + + LVS      V+ W    +  ++  + +D V  V
Sbjct: 297 GHEQDIYSLDFFPDGDRLVSGSGDRSVRIWDLRTSQCSLTLSIEDGVTTV 346

 Score = 31.2 bits (69), Expect = 3.6
 Identities = 21/99 (21%), Positives = 47/99 (47%), Gaps = 6/99 (6%)
 Frame = +2

Query: 449 NKNKCPIYAVCWTPDGRRLITGASSGEFTLWN-----GLTFNFETILQAHDTHIRAMKWS 613
           N ++  +Y+V ++ +G ++ +G+      LW+           E     H   + ++  +
Sbjct: 386 NGHEDSVYSVAFSNNGEQIASGSLDRTVKLWHLEGKSDKKSTCEVTYIGHKDFVLSVCCT 445

Query: 614 NNEEWLVSADDSGFVKYW-QANMNDVNVFQAHKDSVRGV 727
            + E+++S      V +W QA+ N + + Q H++SV  V
Sbjct: 446 PDNEYILSGSKDRGVIFWDQASGNPLLMLQGHRNSVISV 484
>sp|O88342|WDR1_MOUSE WD-repeat protein 1 (Actin-interacting protein 1) (AIP1)
          Length = 606

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 25/77 (32%), Positives = 39/77 (50%), Gaps = 3/77 (3%)
 Frame = +2

Query: 467 IYAVCWTPDGRRLITGASSGEFTLWNGLTFNFETIL---QAHDTHIRAMKWSNNEEWLVS 637
           +  V ++PDG R  T ++ G+  +++G T      L   +AHD  I A+ WS +   L+S
Sbjct: 192 VNCVRFSPDGNRFATASADGQIFIYDGKTGEKVCALGESKAHDGGIYAISWSPDSTHLLS 251

Query: 638 ADDSGFVKYWQANMNDV 688
           A      K W  N+N V
Sbjct: 252 ASGDKTSKIWDVNVNSV 268
>sp|P25382|YCW2_YEAST Hypothetical WD-repeat protein YCR072C
          Length = 515

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 22/82 (26%), Positives = 38/82 (46%), Gaps = 1/82 (1%)
 Frame = +2

Query: 476 VCWTPDGRRLITGASSGEFTLWNGLTFNFETILQAHDTHIRAMKWSNNEEWLVSADDSGF 655
           V ++PDGR +++ +      LW+G    F +  + H   +  + WS++   LVS      
Sbjct: 408 VAFSPDGRYIVSASFDNSIKLWDGRDGKFISTFRGHVASVYQVAWSSDCRLLVSCSKDTT 467

Query: 656 VKYWQANMNDVNV-FQAHKDSV 718
           +K W      ++V    HKD V
Sbjct: 468 LKVWDVRTRKLSVDLPGHKDEV 489

 Score = 33.1 bits (74), Expect = 0.94
 Identities = 18/75 (24%), Positives = 31/75 (41%), Gaps = 8/75 (10%)
 Frame = +2

Query: 467 IYAVCWTPDGRRLITGASSGEFTLWNGLTFN-FETILQAHDTHIRAMKWS-------NNE 622
           +  V W+PDG  + TG+      LW+  +       L+ H   I ++ W         ++
Sbjct: 189 VLCVSWSPDGEVIATGSMDNTIRLWDPKSGQCLGDALRGHSKWITSLSWEPIHLVKPGSK 248

Query: 623 EWLVSADDSGFVKYW 667
             L S+   G +K W
Sbjct: 249 PRLASSSKDGTIKIW 263

 Score = 33.1 bits (74), Expect = 0.94
 Identities = 15/67 (22%), Positives = 28/67 (41%)
 Frame = +2

Query: 467 IYAVCWTPDGRRLITGASSGEFTLWNGLTFNFETILQAHDTHIRAMKWSNNEEWLVSADD 646
           +Y V W+ D R L++ +      +W+  T      L  H   +  + WS + + + S   
Sbjct: 447 VYQVAWSSDCRLLVSCSKDTTLKVWDVRTRKLSVDLPGHKDEVYTVDWSVDGKRVCSGGK 506

Query: 647 SGFVKYW 667
              V+ W
Sbjct: 507 DKMVRLW 513
>sp|P38262|SIF2_YEAST SIR4-interacting protein SIF2
          Length = 535

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 21/75 (28%), Positives = 35/75 (46%)
 Frame = +2

Query: 443 STNKNKCPIYAVCWTPDGRRLITGASSGEFTLWNGLTFNFETILQAHDTHIRAMKWSNNE 622
           S+ K    +  + W+ DG  ++TG  +GE  LWN  T     +L  H   I ++KW+ + 
Sbjct: 215 SSGKTTNQVTCLAWSHDGNSIVTGVENGELRLWN-KTGALLNVLNFHRAPIVSVKWNKDG 273

Query: 623 EWLVSADDSGFVKYW 667
             ++S D       W
Sbjct: 274 THIISMDVENVTILW 288

 Score = 31.2 bits (69), Expect = 3.6
 Identities = 22/81 (27%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
 Frame = +2

Query: 482 WTPDGRRLITGASSGEFTLWNGLTFNFET-ILQAHDTHIRAMKWSNNEEWLVSADDSGFV 658
           W  D + +I G     F     +T    T  L  H   I  +++++  + L+SA D G +
Sbjct: 326 WVDDDKFVIPGPKGAIFVYQ--ITEKTPTGKLIGHHGPISVLEFNDTNKLLLSASDDGTL 383

Query: 659 KYWQ-ANMNDVNVFQAHKDSV 718
           + W   N N  N F  H  S+
Sbjct: 384 RIWHGGNGNSQNCFYGHSQSI 404
>sp|O75083|WDR1_HUMAN WD-repeat protein 1 (Actin interacting protein 1) (AIP1) (NORI-1)
          Length = 606

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 24/77 (31%), Positives = 39/77 (50%), Gaps = 3/77 (3%)
 Frame = +2

Query: 467 IYAVCWTPDGRRLITGASSGEFTLWNGLTFNFETIL---QAHDTHIRAMKWSNNEEWLVS 637
           +  V ++PDG R  T ++ G+  +++G T      L   +AHD  I A+ WS +   L+S
Sbjct: 192 VNCVRFSPDGNRFATASADGQIYIYDGKTGEKVCALGGSKAHDGGIYAISWSPDSTHLLS 251

Query: 638 ADDSGFVKYWQANMNDV 688
           A      K W  ++N V
Sbjct: 252 ASGDKTSKIWDVSVNSV 268
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 87,664,111
Number of Sequences: 369166
Number of extensions: 1744666
Number of successful extensions: 4718
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3921
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4644
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7859674995
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)