Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_02046 (641 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|O42980|YBE1_SCHPO Putative thiol protease C17D11.01 36 0.096 sp|Q8TEW0|PARD3_HUMAN Partitioning-defective 3 homolog (PAR... 35 0.13 sp|P32242|OTX1_HUMAN Homeobox protein OTX1 35 0.16 sp|Q63410|OTX1_RAT Homeobox protein OTX1 35 0.16 sp|P80205|OTX1_MOUSE Homeobox protein OTX1 35 0.16 sp|P31264|HMPB_DROME Homeotic proboscipedia protein 35 0.21 sp|O35181|NRG3_MOUSE Pro-neuregulin-3, membrane-bound isofo... 34 0.28 sp|O14258|ACE2_SCHPO Metallothionein expression activator 33 0.48 sp|P56975|NRG3_HUMAN Pro-neuregulin-3, membrane-bound isofo... 33 0.62 sp|Q9WUX3|RNAS1_RATRT Ribonuclease pancreatic precursor (RN... 32 1.4
>sp|O42980|YBE1_SCHPO Putative thiol protease C17D11.01 Length = 420 Score = 35.8 bits (81), Expect = 0.096 Identities = 20/61 (32%), Positives = 27/61 (44%) Frame = +3 Query: 144 PQSNDSAFYDSYYPNVYSPPSNHRDNSQLYLSSDSFVLDHHSESPPPSQLNCNSHHHHQQ 323 P+S+DS S S+ NS L SS+S +HH+ L+ HHHH Sbjct: 256 PKSSDS-----------SETSHESSNSNLKKSSESGSTNHHNNHESDKDLHHEGHHHHHH 304 Query: 324 H 326 H Sbjct: 305 H 305
>sp|Q8TEW0|PARD3_HUMAN Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific interacting protein) (ASIP) (CTCL tumor antigen se2-5) (PAR3-alpha) Length = 1356 Score = 35.4 bits (80), Expect = 0.13 Identities = 22/72 (30%), Positives = 35/72 (48%) Frame = +3 Query: 111 HRVAAANNQYYPQSNDSAFYDSYYPNVYSPPSNHRDNSQLYLSSDSFVLDHHSESPPPSQ 290 H V AAN + Y Q + S ++YY + +SP S + DN + + V + PP Q Sbjct: 356 HVVPAANKEQYEQLSQSE-KNNYYSSRFSPDSQYIDNRSVNSAGLHTVQRAPRLNHPPEQ 414 Query: 291 LNCNSHHHHQQH 326 ++ +S H H Sbjct: 415 IDSHSRLPHSAH 426
>sp|P32242|OTX1_HUMAN Homeobox protein OTX1 Length = 354 Score = 35.0 bits (79), Expect = 0.16 Identities = 21/68 (30%), Positives = 29/68 (42%), Gaps = 4/68 (5%) Frame = +3 Query: 135 QYYPQSNDSAFYDSYYPNVYSPPSNHRDNSQLYLSSDSFVLDHHSESP----PPSQLNCN 302 Q YP + S F + +P +H QL + S + HH P P SQ + + Sbjct: 233 QGYPTPSSSYFGGVDCSSYLAPMHSHHHPHQLSPMAPSSMAGHHHHHPHAHHPLSQSSGH 292 Query: 303 SHHHHQQH 326 HHHH H Sbjct: 293 HHHHHHHH 300
>sp|Q63410|OTX1_RAT Homeobox protein OTX1 Length = 355 Score = 35.0 bits (79), Expect = 0.16 Identities = 21/68 (30%), Positives = 29/68 (42%), Gaps = 4/68 (5%) Frame = +3 Query: 135 QYYPQSNDSAFYDSYYPNVYSPPSNHRDNSQLYLSSDSFVLDHHSESP----PPSQLNCN 302 Q YP + S F + +P +H QL + S + HH P P SQ + + Sbjct: 233 QGYPAPSSSYFGGVDCSSYLAPMHSHHHPHQLSPMAPSSMAGHHHHHPHAHHPLSQSSGH 292 Query: 303 SHHHHQQH 326 HHHH H Sbjct: 293 HHHHHHHH 300
>sp|P80205|OTX1_MOUSE Homeobox protein OTX1 Length = 355 Score = 35.0 bits (79), Expect = 0.16 Identities = 21/68 (30%), Positives = 29/68 (42%), Gaps = 4/68 (5%) Frame = +3 Query: 135 QYYPQSNDSAFYDSYYPNVYSPPSNHRDNSQLYLSSDSFVLDHHSESP----PPSQLNCN 302 Q YP + S F + +P +H QL + S + HH P P SQ + + Sbjct: 233 QGYPAPSSSYFGGVDCSSYLAPMHSHHHPHQLSPMAPSSMAGHHHHHPHAHHPLSQSSGH 292 Query: 303 SHHHHQQH 326 HHHH H Sbjct: 293 HHHHHHHH 300
>sp|P31264|HMPB_DROME Homeotic proboscipedia protein Length = 782 Score = 34.7 bits (78), Expect = 0.21 Identities = 19/68 (27%), Positives = 31/68 (45%) Frame = +3 Query: 123 AANNQYYPQSNDSAFYDSYYPNVYSPPSNHRDNSQLYLSSDSFVLDHHSESPPPSQLNCN 302 AA+ + P + A + Y S + H+ NSQ +D F +++ + P + Sbjct: 505 AASPHHNPHNKQQALHGEYLSPKPSSANFHQ-NSQQQQQNDHFYYNYNDTNGTPYLNHQQ 563 Query: 303 SHHHHQQH 326 HHHH QH Sbjct: 564 QHHHHAQH 571
>sp|O35181|NRG3_MOUSE Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)] Length = 713 Score = 34.3 bits (77), Expect = 0.28 Identities = 41/141 (29%), Positives = 50/141 (35%) Frame = +1 Query: 196 PRHQIIATTASSTYLPIVSFWTTTASLRRPLNSIAIVIITISNMLSLVIMIPGRNNQSSI 375 P+ TT +ST P AS R P N I+ + TI+ + PG Sbjct: 122 PKAMETTTTTTSTTSPATPSAGGAASSRTP-NRISTRLTTITRAPT---RFPGHRVPIRA 177 Query: 376 QPIATTATVLPFQWRSNKTIMPTTLVTGM*NIFGKIAPLIPVLTIHHRPPLLGCPRSTMR 555 P +TTA N PT L T AP T RPP+ G P + Sbjct: 178 SPRSTTAR--------NTAAPPTVLST--------TAPFFSSSTPGSRPPMPGAPSTQAM 221 Query: 556 PLEPCPALVTCSISCHPRLPS 618 P P A T S H PS Sbjct: 222 PSWPTAAYATSSY-LHDSTPS 241
>sp|O14258|ACE2_SCHPO Metallothionein expression activator Length = 533 Score = 33.5 bits (75), Expect = 0.48 Identities = 28/82 (34%), Positives = 38/82 (46%), Gaps = 11/82 (13%) Frame = +3 Query: 144 PQSNDSAFYDSY-YPNVYSPPSNH--RDNSQLYLSSDSFVLDHHSE--------SPPPSQ 290 P S+ F D + Y +V P N NS +LS+ + D HS SPP S Sbjct: 64 PPSHLQNFQDQFDYSSVLKTPFNPLLEANSAYFLSNQISLPDSHSYASSFDASLSPPSSP 123 Query: 291 LNCNSHHHHQQHVVTGNNDSWS 356 L C S H +Q+ NND++S Sbjct: 124 LTCVSQIHTEQNF--NNNDAFS 143
>sp|P56975|NRG3_HUMAN Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3) [Contains: Neuregulin-3 (NRG-3)] Length = 720 Score = 33.1 bits (74), Expect = 0.62 Identities = 39/141 (27%), Positives = 51/141 (36%) Frame = +1 Query: 196 PRHQIIATTASSTYLPIVSFWTTTASLRRPLNSIAIVIITISNMLSLVIMIPGRNNQSSI 375 P+ TT +ST P AS R P N I+ + TI+ + PG Sbjct: 122 PKAMETTTTTTSTTSPATPSAGGAASSRTP-NRISTRLTTITRAPT---RFPGHRVPIRA 177 Query: 376 QPIATTATVLPFQWRSNKTIMPTTLVTGM*NIFGKIAPLIPVLTIHHRPPLLGCPRSTMR 555 P +TTA T P T+ + AP T+ RPP+ G P + Sbjct: 178 SPRSTTA---------RNTAAPATVPS-------TTAPFFSSSTLGSRPPVPGTPSTQAM 221 Query: 556 PLEPCPALVTCSISCHPRLPS 618 P P A T S H PS Sbjct: 222 PSWPTAAYATSSY-LHDSTPS 241
>sp|Q9WUX3|RNAS1_RATRT Ribonuclease pancreatic precursor (RNase 1) (RNase A) Length = 152 Score = 32.0 bits (71), Expect = 1.4 Identities = 22/82 (26%), Positives = 32/82 (39%), Gaps = 1/82 (1%) Frame = -3 Query: 633 LVVSDGWETRMTADAASDECRARFQRPHCRPWTPKKRRPMVNCQDWNQWCN-FSKDISHS 457 LV+ GW + + +F+R H P +P K P +CN K + Sbjct: 13 LVLVLGWVQPSLGVESRESSADKFKRQHMDPESPSKSSP--------TYCNQMMKRQGMT 64 Query: 456 RNECRRHNCFVGSPLERQHCCC 391 + C+ N FV PLE C Sbjct: 65 KGSCKPVNTFVHEPLEDVQAIC 86
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 81,072,410 Number of Sequences: 369166 Number of extensions: 1715367 Number of successful extensions: 6016 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 5295 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5860 length of database: 68,354,980 effective HSP length: 106 effective length of database: 48,773,070 effective search space used: 5218718490 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)