Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_014_A14
(641 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O42980|YBE1_SCHPO Putative thiol protease C17D11.01 36 0.096
sp|Q8TEW0|PARD3_HUMAN Partitioning-defective 3 homolog (PAR... 35 0.13
sp|P32242|OTX1_HUMAN Homeobox protein OTX1 35 0.16
sp|Q63410|OTX1_RAT Homeobox protein OTX1 35 0.16
sp|P80205|OTX1_MOUSE Homeobox protein OTX1 35 0.16
sp|P31264|HMPB_DROME Homeotic proboscipedia protein 35 0.21
sp|O35181|NRG3_MOUSE Pro-neuregulin-3, membrane-bound isofo... 34 0.28
sp|O14258|ACE2_SCHPO Metallothionein expression activator 33 0.48
sp|P56975|NRG3_HUMAN Pro-neuregulin-3, membrane-bound isofo... 33 0.62
sp|Q9WUX3|RNAS1_RATRT Ribonuclease pancreatic precursor (RN... 32 1.4
>sp|O42980|YBE1_SCHPO Putative thiol protease C17D11.01
Length = 420
Score = 35.8 bits (81), Expect = 0.096
Identities = 20/61 (32%), Positives = 27/61 (44%)
Frame = +3
Query: 144 PQSNDSAFYDSYYPNVYSPPSNHRDNSQLYLSSDSFVLDHHSESPPPSQLNCNSHHHHQQ 323
P+S+DS S S+ NS L SS+S +HH+ L+ HHHH
Sbjct: 256 PKSSDS-----------SETSHESSNSNLKKSSESGSTNHHNNHESDKDLHHEGHHHHHH 304
Query: 324 H 326
H
Sbjct: 305 H 305
>sp|Q8TEW0|PARD3_HUMAN Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC
isotype-specific interacting protein) (ASIP) (CTCL tumor
antigen se2-5) (PAR3-alpha)
Length = 1356
Score = 35.4 bits (80), Expect = 0.13
Identities = 22/72 (30%), Positives = 35/72 (48%)
Frame = +3
Query: 111 HRVAAANNQYYPQSNDSAFYDSYYPNVYSPPSNHRDNSQLYLSSDSFVLDHHSESPPPSQ 290
H V AAN + Y Q + S ++YY + +SP S + DN + + V + PP Q
Sbjct: 356 HVVPAANKEQYEQLSQSE-KNNYYSSRFSPDSQYIDNRSVNSAGLHTVQRAPRLNHPPEQ 414
Query: 291 LNCNSHHHHQQH 326
++ +S H H
Sbjct: 415 IDSHSRLPHSAH 426
>sp|P32242|OTX1_HUMAN Homeobox protein OTX1
Length = 354
Score = 35.0 bits (79), Expect = 0.16
Identities = 21/68 (30%), Positives = 29/68 (42%), Gaps = 4/68 (5%)
Frame = +3
Query: 135 QYYPQSNDSAFYDSYYPNVYSPPSNHRDNSQLYLSSDSFVLDHHSESP----PPSQLNCN 302
Q YP + S F + +P +H QL + S + HH P P SQ + +
Sbjct: 233 QGYPTPSSSYFGGVDCSSYLAPMHSHHHPHQLSPMAPSSMAGHHHHHPHAHHPLSQSSGH 292
Query: 303 SHHHHQQH 326
HHHH H
Sbjct: 293 HHHHHHHH 300
>sp|Q63410|OTX1_RAT Homeobox protein OTX1
Length = 355
Score = 35.0 bits (79), Expect = 0.16
Identities = 21/68 (30%), Positives = 29/68 (42%), Gaps = 4/68 (5%)
Frame = +3
Query: 135 QYYPQSNDSAFYDSYYPNVYSPPSNHRDNSQLYLSSDSFVLDHHSESP----PPSQLNCN 302
Q YP + S F + +P +H QL + S + HH P P SQ + +
Sbjct: 233 QGYPAPSSSYFGGVDCSSYLAPMHSHHHPHQLSPMAPSSMAGHHHHHPHAHHPLSQSSGH 292
Query: 303 SHHHHQQH 326
HHHH H
Sbjct: 293 HHHHHHHH 300
>sp|P80205|OTX1_MOUSE Homeobox protein OTX1
Length = 355
Score = 35.0 bits (79), Expect = 0.16
Identities = 21/68 (30%), Positives = 29/68 (42%), Gaps = 4/68 (5%)
Frame = +3
Query: 135 QYYPQSNDSAFYDSYYPNVYSPPSNHRDNSQLYLSSDSFVLDHHSESP----PPSQLNCN 302
Q YP + S F + +P +H QL + S + HH P P SQ + +
Sbjct: 233 QGYPAPSSSYFGGVDCSSYLAPMHSHHHPHQLSPMAPSSMAGHHHHHPHAHHPLSQSSGH 292
Query: 303 SHHHHQQH 326
HHHH H
Sbjct: 293 HHHHHHHH 300
>sp|P31264|HMPB_DROME Homeotic proboscipedia protein
Length = 782
Score = 34.7 bits (78), Expect = 0.21
Identities = 19/68 (27%), Positives = 31/68 (45%)
Frame = +3
Query: 123 AANNQYYPQSNDSAFYDSYYPNVYSPPSNHRDNSQLYLSSDSFVLDHHSESPPPSQLNCN 302
AA+ + P + A + Y S + H+ NSQ +D F +++ + P +
Sbjct: 505 AASPHHNPHNKQQALHGEYLSPKPSSANFHQ-NSQQQQQNDHFYYNYNDTNGTPYLNHQQ 563
Query: 303 SHHHHQQH 326
HHHH QH
Sbjct: 564 QHHHHAQH 571
>sp|O35181|NRG3_MOUSE Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3)
[Contains: Neuregulin-3 (NRG-3)]
Length = 713
Score = 34.3 bits (77), Expect = 0.28
Identities = 41/141 (29%), Positives = 50/141 (35%)
Frame = +1
Query: 196 PRHQIIATTASSTYLPIVSFWTTTASLRRPLNSIAIVIITISNMLSLVIMIPGRNNQSSI 375
P+ TT +ST P AS R P N I+ + TI+ + PG
Sbjct: 122 PKAMETTTTTTSTTSPATPSAGGAASSRTP-NRISTRLTTITRAPT---RFPGHRVPIRA 177
Query: 376 QPIATTATVLPFQWRSNKTIMPTTLVTGM*NIFGKIAPLIPVLTIHHRPPLLGCPRSTMR 555
P +TTA N PT L T AP T RPP+ G P +
Sbjct: 178 SPRSTTAR--------NTAAPPTVLST--------TAPFFSSSTPGSRPPMPGAPSTQAM 221
Query: 556 PLEPCPALVTCSISCHPRLPS 618
P P A T S H PS
Sbjct: 222 PSWPTAAYATSSY-LHDSTPS 241
>sp|O14258|ACE2_SCHPO Metallothionein expression activator
Length = 533
Score = 33.5 bits (75), Expect = 0.48
Identities = 28/82 (34%), Positives = 38/82 (46%), Gaps = 11/82 (13%)
Frame = +3
Query: 144 PQSNDSAFYDSY-YPNVYSPPSNH--RDNSQLYLSSDSFVLDHHSE--------SPPPSQ 290
P S+ F D + Y +V P N NS +LS+ + D HS SPP S
Sbjct: 64 PPSHLQNFQDQFDYSSVLKTPFNPLLEANSAYFLSNQISLPDSHSYASSFDASLSPPSSP 123
Query: 291 LNCNSHHHHQQHVVTGNNDSWS 356
L C S H +Q+ NND++S
Sbjct: 124 LTCVSQIHTEQNF--NNNDAFS 143
>sp|P56975|NRG3_HUMAN Pro-neuregulin-3, membrane-bound isoform precursor (Pro-NRG3)
[Contains: Neuregulin-3 (NRG-3)]
Length = 720
Score = 33.1 bits (74), Expect = 0.62
Identities = 39/141 (27%), Positives = 51/141 (36%)
Frame = +1
Query: 196 PRHQIIATTASSTYLPIVSFWTTTASLRRPLNSIAIVIITISNMLSLVIMIPGRNNQSSI 375
P+ TT +ST P AS R P N I+ + TI+ + PG
Sbjct: 122 PKAMETTTTTTSTTSPATPSAGGAASSRTP-NRISTRLTTITRAPT---RFPGHRVPIRA 177
Query: 376 QPIATTATVLPFQWRSNKTIMPTTLVTGM*NIFGKIAPLIPVLTIHHRPPLLGCPRSTMR 555
P +TTA T P T+ + AP T+ RPP+ G P +
Sbjct: 178 SPRSTTA---------RNTAAPATVPS-------TTAPFFSSSTLGSRPPVPGTPSTQAM 221
Query: 556 PLEPCPALVTCSISCHPRLPS 618
P P A T S H PS
Sbjct: 222 PSWPTAAYATSSY-LHDSTPS 241
>sp|Q9WUX3|RNAS1_RATRT Ribonuclease pancreatic precursor (RNase 1) (RNase A)
Length = 152
Score = 32.0 bits (71), Expect = 1.4
Identities = 22/82 (26%), Positives = 32/82 (39%), Gaps = 1/82 (1%)
Frame = -3
Query: 633 LVVSDGWETRMTADAASDECRARFQRPHCRPWTPKKRRPMVNCQDWNQWCN-FSKDISHS 457
LV+ GW + + +F+R H P +P K P +CN K +
Sbjct: 13 LVLVLGWVQPSLGVESRESSADKFKRQHMDPESPSKSSP--------TYCNQMMKRQGMT 64
Query: 456 RNECRRHNCFVGSPLERQHCCC 391
+ C+ N FV PLE C
Sbjct: 65 KGSCKPVNTFVHEPLEDVQAIC 86
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 81,072,410
Number of Sequences: 369166
Number of extensions: 1715367
Number of successful extensions: 6016
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5295
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5860
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5218718490
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)