Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_02040 (833 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q62921|UB7I3_RAT Ubiquitin-conjugating enzyme 7-interact... 101 3e-21 sp|Q9WUB0|UB7I3_MOUSE Ubiquitin-conjugating enzyme 7-intera... 97 5e-20 sp|Q9BYM8|UB7I3_HUMAN Ubiquitin-conjugating enzyme 7-intera... 94 4e-19 sp|P36113|YKZ7_YEAST Hypothetical 63.6 kDa protein in YPT52... 42 0.002 sp|Q22431|ARI2_CAEEL Probable ariadne-2 protein (Ari-2) 42 0.002 sp|O95376|ARI2_HUMAN Ariadne-2 protein homolog (ARI-2) (Tri... 39 0.014 sp|Q9Y4X5|ARI1_HUMAN Ariadne-1 protein homolog (ARI-1) (Ubi... 38 0.030 sp|Q9Z1K5|ARI1_MOUSE Ariadne-1 protein homolog (ARI-1) (Ubi... 38 0.030 sp|Q04638|YMG8_YEAST Hypothetical 54.1 kDa protein in DAK1-... 37 0.051 sp|Q9Z1K6|ARI2_MOUSE Ariadne-2 protein homolog (ARI-2) (Tri... 37 0.067
>sp|Q62921|UB7I3_RAT Ubiquitin-conjugating enzyme 7-interacting protein 3 (RBCC protein interacting with PKC) (Protein kinase C-binding protein beta-15) Length = 498 Score = 101 bits (251), Expect = 3e-21 Identities = 56/211 (26%), Positives = 90/211 (42%), Gaps = 10/211 (4%) Frame = -2 Query: 829 CGHKCCTSCFKKKIAVNPFYPIEC------FQCSQVLTDDECLKYFSSEQATKYLNSKTY 668 C H C C + I + + C + C L + E S E ++L+ Sbjct: 288 CLHTFCRECLQGTIRNSQEAEVSCPFIDNTYSCPGKLLEREIRALLSPEDYQRFLDLGVS 347 Query: 667 LNEILNEKLLKCFNVDCDGRIENVNVPSSYRCSACNKLNCMHCRTTHLDGETCDQWQINN 488 + E + C DC G + + + C C ++NC+ C+ H + C ++Q + Sbjct: 348 IAENRSTLSYHCKTPDCRGWCFFEDDVNEFTCPVCTRVNCLLCKAIH-ERMNCREYQDDL 406 Query: 487 KHXXXXXXXXXXXXXXXXXXXI---AMYCVKCGTLCERDGGCYGVKCPICKTALCFITQK 317 H AMYC +C + ++ GC ++C +C T +C++T+ Sbjct: 407 AHRARNDVAAQQTTEMLRVMLQQGEAMYCPQCRIVVQKKDGCDWIRCTVCHTEICWVTKG 466 Query: 316 ARWGPQGVGDLSSGCKCSF-GNPCHRSCGSC 227 RWGP G GD S GC+C G PCH SC +C Sbjct: 467 PRWGPGGPGDTSGGCRCRVNGIPCHPSCQNC 497
>sp|Q9WUB0|UB7I3_MOUSE Ubiquitin-conjugating enzyme 7-interacting protein 3 (UbcM4-interacting protein 28) Length = 498 Score = 97.1 bits (240), Expect = 5e-20 Identities = 54/211 (25%), Positives = 89/211 (42%), Gaps = 10/211 (4%) Frame = -2 Query: 829 CGHKCCTSCFKKKIAVNPFYPIEC------FQCSQVLTDDECLKYFSSEQATKYLNSKTY 668 C H C C + I + + C + C L + E S E ++L+ Sbjct: 288 CLHTFCRECLQGTIRNSQEAEVACPFIDSTYSCPGKLLEREIRALLSPEDYQRFLDLGVS 347 Query: 667 LNEILNEKLLKCFNVDCDGRIENVNVPSSYRCSACNKLNCMHCRTTHLDGETCDQWQIN- 491 + E + C DC G + + + C C ++NC+ C+ H + C ++Q + Sbjct: 348 IAENRSTLSYHCKTPDCRGWCFFEDDVNEFTCPVCTRVNCLLCKAIH-EHMNCREYQDDL 406 Query: 490 --NKHXXXXXXXXXXXXXXXXXXXIAMYCVKCGTLCERDGGCYGVKCPICKTALCFITQK 317 AM+C +C + ++ GC ++C +C T +C++T+ Sbjct: 407 ALRAQNDVAARQTTEMLKVMLQQGEAMHCPQCRIVVQKKDGCDWIRCTVCHTEICWVTKG 466 Query: 316 ARWGPQGVGDLSSGCKCSF-GNPCHRSCGSC 227 RWGP G GD S GC+C G PCH SC +C Sbjct: 467 PRWGPGGPGDTSGGCRCRVNGIPCHPSCQNC 497
>sp|Q9BYM8|UB7I3_HUMAN Ubiquitin-conjugating enzyme 7-interacting protein 3 (Hepatitis B virus X-associated protein 4) (HBV-associated factor 4) (RING finger protein 54) Length = 500 Score = 94.4 bits (233), Expect = 4e-19 Identities = 54/211 (25%), Positives = 88/211 (41%), Gaps = 10/211 (4%) Frame = -2 Query: 829 CGHKCCTSCFKKKIAVNPFYPIEC------FQCSQVLTDDECLKYFSSEQATKYLNSKTY 668 C H C C + I + + C + CS L + E + E ++L+ Sbjct: 290 CLHTFCRECLQGTIRNSQEAEVSCPFIDNTYSCSGKLLEREIKALLTPEDYQRFLDLGIS 349 Query: 667 LNEILNEKLLKCFNVDCDGRIENVNVPSSYRCSACNKLNCMHCRTTHLDGETCDQWQIN- 491 + E + C DC G + + + C C +NC+ C+ H + C ++Q + Sbjct: 350 IAENRSAFSYHCKTPDCKGWCFFEDDVNEFTCPVCFHVNCLLCKAIH-EQMNCKEYQEDL 408 Query: 490 --NKHXXXXXXXXXXXXXXXXXXXIAMYCVKCGTLCERDGGCYGVKCPICKTALCFITQK 317 AM C +C + ++ GC ++C +C T +C++T+ Sbjct: 409 ALRAQNDVAARQTTEMLKVMLQQGEAMRCPQCQIVVQKKDGCDWIRCTVCHTEICWVTKG 468 Query: 316 ARWGPQGVGDLSSGCKCSF-GNPCHRSCGSC 227 RWGP G GD S GC+C G PCH SC +C Sbjct: 469 PRWGPGGPGDTSGGCRCRVNGIPCHPSCQNC 499
>sp|P36113|YKZ7_YEAST Hypothetical 63.6 kDa protein in YPT52-GCN3 intergenic region Length = 551 Score = 42.4 bits (98), Expect = 0.002 Identities = 38/187 (20%), Positives = 72/187 (38%), Gaps = 9/187 (4%) Frame = -2 Query: 829 CGHKCCTSCFKKKIA--VNPFYPIECFQCSQVLTDDECLKYFSSEQATKYLNS--KTYLN 662 CGH+ C +C++ I ++ I C CS L +++ K ++K ++S K+++ Sbjct: 195 CGHEYCINCYRHYIKDKLHEGNIITCMDCSLALKNEDIDKVMGHPSSSKLMDSSIKSFVQ 254 Query: 661 EILNEKLLKCFNVDCDGRIENVNVPSSYRCSACNKLNCMHCRTTHLDGETCDQWQINNKH 482 + N C DC + + S + + + C + H C +++++ Sbjct: 255 KH-NRNYKWCPFADCKSIVHLRDTSSLPEYTRLHYSPFVKCNSFHRFCFNCG-FEVHSPA 312 Query: 481 XXXXXXXXXXXXXXXXXXXIAMY-----CVKCGTLCERDGGCYGVKCPICKTALCFITQK 317 + C KC E++GGC + C CK C+I + Sbjct: 313 DCKITTAWVKKARKESEILNWVLSHTKECPKCSVNIEKNGGCNHMVCSSCKYEFCWICE- 371 Query: 316 ARWGPQG 296 W P G Sbjct: 372 GPWAPHG 378
>sp|Q22431|ARI2_CAEEL Probable ariadne-2 protein (Ari-2) Length = 482 Score = 42.0 bits (97), Expect = 0.002 Identities = 37/180 (20%), Positives = 61/180 (33%), Gaps = 12/180 (6%) Frame = -2 Query: 829 CGHKCCTSCFK----KKIAVNPFYPIECF--QCSQVLTDDECLKYFSSEQATKYLNSKTY 668 CGH C C+K +++ IEC +C + L + K + Sbjct: 145 CGHCFCEHCWKSHVESRLSEGVASRIECMESECEVYAPSEFVLSIIKNSPVIKLKYERFL 204 Query: 667 LNEILNE--KLLKCFNVDCDGRIENVNV-PSSYRCSACNKLNCMHCRTTH---LDGETCD 506 L +++N L C +C I + V P C C+ C+ C + ET Sbjct: 205 LRDMVNSHPHLKFCVGNECPVIIRSTEVKPKRVTCMQCHTSFCVKCGADYHAPTSCETIK 264 Query: 505 QWQINNKHXXXXXXXXXXXXXXXXXXXIAMYCVKCGTLCERDGGCYGVKCPICKTALCFI 326 QW C +C + E+ GGC ++C C+ C++ Sbjct: 265 QWMTK---------CADDSETANYISAHTKDCPQCHSCIEKAGGCNHIQCTRCRHHFCWM 315
>sp|O95376|ARI2_HUMAN Ariadne-2 protein homolog (ARI-2) (Triad1 protein) Length = 493 Score = 39.3 bits (90), Expect = 0.014 Identities = 37/180 (20%), Positives = 65/180 (36%), Gaps = 12/180 (6%) Frame = -2 Query: 829 CGHKCCTSCFKKKIAV----NPFYPIECF--QCSQVLTDDECLKYFSSEQATKYLNSKTY 668 C H+ C SC+++ +V + C C +D +E+ + + Sbjct: 156 CQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQDCPLRTPEDFVFPLLPNEELREKYRRYLF 215 Query: 667 LNEILNEKLLK-CFNVDCDGRIENVNVPSSYR--CSACNKLNCMHCRTTH---LDGETCD 506 + + + L+ C DC + V P + R C+ CN++ C CR + D T Sbjct: 216 RDYVESHYQLQLCPGADCP-MVIRVQEPRARRVQCNRCNEVFCFKCRQMYHAPTDCATIR 274 Query: 505 QWQINNKHXXXXXXXXXXXXXXXXXXXIAMYCVKCGTLCERDGGCYGVKCPICKTALCFI 326 +W C KC E++GGC ++C CK C++ Sbjct: 275 KWLTK---------CADDSETANYISAHTKDCPKCNICIEKNGGCNHMQCSKCKHDFCWM 325
>sp|Q9Y4X5|ARI1_HUMAN Ariadne-1 protein homolog (ARI-1) (Ubiquitin-conjugating enzyme E2-binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein) (HHARI) (H7-AP2) (MOP-6) Length = 557 Score = 38.1 bits (87), Expect = 0.030 Identities = 44/190 (23%), Positives = 62/190 (32%), Gaps = 12/190 (6%) Frame = -2 Query: 829 CGHKCCTSCFKKKIAVNPF-----YPIEC-FQCSQVLTDDECLKYFSSEQATKYLNSKTY 668 CGHK C C+ + + I C +L DD + ++ K Sbjct: 203 CGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDDNTVMRLITDSKVKLKYQHLI 262 Query: 667 LNEILN-EKLLK-CFNVDCDGRIENVNVPSS--YRCSACNKLNCMHCRTTHLDGETCDQW 500 N + +LLK C DC + V P + RC C + C +C D C +W Sbjct: 263 TNSFVECNRLLKWCPAPDCH-HVVKVQYPDAKPVRCK-CGRQFCFNCGENWHDPVKC-KW 319 Query: 499 QINNKHXXXXXXXXXXXXXXXXXXXIAMYCVKCGTLCERDGGCYGVKC--PICKTALCFI 326 C KC E+DGGC + C CK C++ Sbjct: 320 L-----KKWIKKCDDDSETSNWIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWV 374 Query: 325 TQKARWGPQG 296 W P G Sbjct: 375 C-LGPWEPHG 383
>sp|Q9Z1K5|ARI1_MOUSE Ariadne-1 protein homolog (ARI-1) (Ubiquitin-conjugating enzyme E2-binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein 77) Length = 555 Score = 38.1 bits (87), Expect = 0.030 Identities = 44/190 (23%), Positives = 62/190 (32%), Gaps = 12/190 (6%) Frame = -2 Query: 829 CGHKCCTSCFKKKIAVNPF-----YPIEC-FQCSQVLTDDECLKYFSSEQATKYLNSKTY 668 CGHK C C+ + + I C +L DD + ++ K Sbjct: 201 CGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDDNTVMRLITDSKVKLKYQHLI 260 Query: 667 LNEILN-EKLLK-CFNVDCDGRIENVNVPSS--YRCSACNKLNCMHCRTTHLDGETCDQW 500 N + +LLK C DC + V P + RC C + C +C D C +W Sbjct: 261 TNSFVECNRLLKWCPAPDCH-HVVKVQYPDAKPVRCK-CGRQFCFNCGENWHDPVKC-KW 317 Query: 499 QINNKHXXXXXXXXXXXXXXXXXXXIAMYCVKCGTLCERDGGCYGVKC--PICKTALCFI 326 C KC E+DGGC + C CK C++ Sbjct: 318 L-----KKWIKKCDDDSETSNWIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWV 372 Query: 325 TQKARWGPQG 296 W P G Sbjct: 373 C-LGPWEPHG 381
>sp|Q04638|YMG8_YEAST Hypothetical 54.1 kDa protein in DAK1-ORC1 intergenic region Length = 464 Score = 37.4 bits (85), Expect = 0.051 Identities = 14/29 (48%), Positives = 17/29 (58%) Frame = -2 Query: 412 CVKCGTLCERDGGCYGVKCPICKTALCFI 326 C KC + ER GC +KC +C T CFI Sbjct: 402 CPKCKVVVERSEGCNKMKCEVCGTLFCFI 430
>sp|Q9Z1K6|ARI2_MOUSE Ariadne-2 protein homolog (ARI-2) (Triad1 protein) (UbcM4-interacting protein 48) Length = 492 Score = 37.0 bits (84), Expect = 0.067 Identities = 37/180 (20%), Positives = 64/180 (35%), Gaps = 12/180 (6%) Frame = -2 Query: 829 CGHKCCTSCFKKKIAV----NPFYPIECF--QCSQVLTDDECLKYFSSEQATKYLNSKTY 668 C H+ C SC+++ +V I C C +D +E+ + Sbjct: 155 CQHQFCRSCWEQHCSVLVKDGVGVGISCMAQDCPLRTPEDFVFPLLPNEELRDKYRRYLF 214 Query: 667 LNEILNE-KLLKCFNVDCDGRIENVNVPSSYR--CSACNKLNCMHCRTTH---LDGETCD 506 + + + +L C DC + V P + R C+ C+++ C CR + D T Sbjct: 215 RDYVESHFQLQLCPGADCP-MVIRVQEPRARRVQCNRCSEVFCFKCRQMYHAPTDCATIR 273 Query: 505 QWQINNKHXXXXXXXXXXXXXXXXXXXIAMYCVKCGTLCERDGGCYGVKCPICKTALCFI 326 +W C KC E++GGC ++C CK C++ Sbjct: 274 KWLTK---------CADDSETANYISAHTKDCPKCNICIEKNGGCNHMQCSKCKHDFCWM 324
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 79,113,314 Number of Sequences: 369166 Number of extensions: 1485539 Number of successful extensions: 4969 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 4659 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4958 length of database: 68,354,980 effective HSP length: 109 effective length of database: 48,218,865 effective search space used: 8100769320 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)