Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_013_P04
(833 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q62921|UB7I3_RAT Ubiquitin-conjugating enzyme 7-interact... 101 3e-21
sp|Q9WUB0|UB7I3_MOUSE Ubiquitin-conjugating enzyme 7-intera... 97 5e-20
sp|Q9BYM8|UB7I3_HUMAN Ubiquitin-conjugating enzyme 7-intera... 94 4e-19
sp|P36113|YKZ7_YEAST Hypothetical 63.6 kDa protein in YPT52... 42 0.002
sp|Q22431|ARI2_CAEEL Probable ariadne-2 protein (Ari-2) 42 0.002
sp|O95376|ARI2_HUMAN Ariadne-2 protein homolog (ARI-2) (Tri... 39 0.014
sp|Q9Y4X5|ARI1_HUMAN Ariadne-1 protein homolog (ARI-1) (Ubi... 38 0.030
sp|Q9Z1K5|ARI1_MOUSE Ariadne-1 protein homolog (ARI-1) (Ubi... 38 0.030
sp|Q04638|YMG8_YEAST Hypothetical 54.1 kDa protein in DAK1-... 37 0.051
sp|Q9Z1K6|ARI2_MOUSE Ariadne-2 protein homolog (ARI-2) (Tri... 37 0.067
>sp|Q62921|UB7I3_RAT Ubiquitin-conjugating enzyme 7-interacting protein 3 (RBCC protein
interacting with PKC) (Protein kinase C-binding protein
beta-15)
Length = 498
Score = 101 bits (251), Expect = 3e-21
Identities = 56/211 (26%), Positives = 90/211 (42%), Gaps = 10/211 (4%)
Frame = -2
Query: 829 CGHKCCTSCFKKKIAVNPFYPIEC------FQCSQVLTDDECLKYFSSEQATKYLNSKTY 668
C H C C + I + + C + C L + E S E ++L+
Sbjct: 288 CLHTFCRECLQGTIRNSQEAEVSCPFIDNTYSCPGKLLEREIRALLSPEDYQRFLDLGVS 347
Query: 667 LNEILNEKLLKCFNVDCDGRIENVNVPSSYRCSACNKLNCMHCRTTHLDGETCDQWQINN 488
+ E + C DC G + + + C C ++NC+ C+ H + C ++Q +
Sbjct: 348 IAENRSTLSYHCKTPDCRGWCFFEDDVNEFTCPVCTRVNCLLCKAIH-ERMNCREYQDDL 406
Query: 487 KHXXXXXXXXXXXXXXXXXXXI---AMYCVKCGTLCERDGGCYGVKCPICKTALCFITQK 317
H AMYC +C + ++ GC ++C +C T +C++T+
Sbjct: 407 AHRARNDVAAQQTTEMLRVMLQQGEAMYCPQCRIVVQKKDGCDWIRCTVCHTEICWVTKG 466
Query: 316 ARWGPQGVGDLSSGCKCSF-GNPCHRSCGSC 227
RWGP G GD S GC+C G PCH SC +C
Sbjct: 467 PRWGPGGPGDTSGGCRCRVNGIPCHPSCQNC 497
>sp|Q9WUB0|UB7I3_MOUSE Ubiquitin-conjugating enzyme 7-interacting protein 3
(UbcM4-interacting protein 28)
Length = 498
Score = 97.1 bits (240), Expect = 5e-20
Identities = 54/211 (25%), Positives = 89/211 (42%), Gaps = 10/211 (4%)
Frame = -2
Query: 829 CGHKCCTSCFKKKIAVNPFYPIEC------FQCSQVLTDDECLKYFSSEQATKYLNSKTY 668
C H C C + I + + C + C L + E S E ++L+
Sbjct: 288 CLHTFCRECLQGTIRNSQEAEVACPFIDSTYSCPGKLLEREIRALLSPEDYQRFLDLGVS 347
Query: 667 LNEILNEKLLKCFNVDCDGRIENVNVPSSYRCSACNKLNCMHCRTTHLDGETCDQWQIN- 491
+ E + C DC G + + + C C ++NC+ C+ H + C ++Q +
Sbjct: 348 IAENRSTLSYHCKTPDCRGWCFFEDDVNEFTCPVCTRVNCLLCKAIH-EHMNCREYQDDL 406
Query: 490 --NKHXXXXXXXXXXXXXXXXXXXIAMYCVKCGTLCERDGGCYGVKCPICKTALCFITQK 317
AM+C +C + ++ GC ++C +C T +C++T+
Sbjct: 407 ALRAQNDVAARQTTEMLKVMLQQGEAMHCPQCRIVVQKKDGCDWIRCTVCHTEICWVTKG 466
Query: 316 ARWGPQGVGDLSSGCKCSF-GNPCHRSCGSC 227
RWGP G GD S GC+C G PCH SC +C
Sbjct: 467 PRWGPGGPGDTSGGCRCRVNGIPCHPSCQNC 497
>sp|Q9BYM8|UB7I3_HUMAN Ubiquitin-conjugating enzyme 7-interacting protein 3 (Hepatitis B
virus X-associated protein 4) (HBV-associated factor 4)
(RING finger protein 54)
Length = 500
Score = 94.4 bits (233), Expect = 4e-19
Identities = 54/211 (25%), Positives = 88/211 (41%), Gaps = 10/211 (4%)
Frame = -2
Query: 829 CGHKCCTSCFKKKIAVNPFYPIEC------FQCSQVLTDDECLKYFSSEQATKYLNSKTY 668
C H C C + I + + C + CS L + E + E ++L+
Sbjct: 290 CLHTFCRECLQGTIRNSQEAEVSCPFIDNTYSCSGKLLEREIKALLTPEDYQRFLDLGIS 349
Query: 667 LNEILNEKLLKCFNVDCDGRIENVNVPSSYRCSACNKLNCMHCRTTHLDGETCDQWQIN- 491
+ E + C DC G + + + C C +NC+ C+ H + C ++Q +
Sbjct: 350 IAENRSAFSYHCKTPDCKGWCFFEDDVNEFTCPVCFHVNCLLCKAIH-EQMNCKEYQEDL 408
Query: 490 --NKHXXXXXXXXXXXXXXXXXXXIAMYCVKCGTLCERDGGCYGVKCPICKTALCFITQK 317
AM C +C + ++ GC ++C +C T +C++T+
Sbjct: 409 ALRAQNDVAARQTTEMLKVMLQQGEAMRCPQCQIVVQKKDGCDWIRCTVCHTEICWVTKG 468
Query: 316 ARWGPQGVGDLSSGCKCSF-GNPCHRSCGSC 227
RWGP G GD S GC+C G PCH SC +C
Sbjct: 469 PRWGPGGPGDTSGGCRCRVNGIPCHPSCQNC 499
>sp|P36113|YKZ7_YEAST Hypothetical 63.6 kDa protein in YPT52-GCN3 intergenic region
Length = 551
Score = 42.4 bits (98), Expect = 0.002
Identities = 38/187 (20%), Positives = 72/187 (38%), Gaps = 9/187 (4%)
Frame = -2
Query: 829 CGHKCCTSCFKKKIA--VNPFYPIECFQCSQVLTDDECLKYFSSEQATKYLNS--KTYLN 662
CGH+ C +C++ I ++ I C CS L +++ K ++K ++S K+++
Sbjct: 195 CGHEYCINCYRHYIKDKLHEGNIITCMDCSLALKNEDIDKVMGHPSSSKLMDSSIKSFVQ 254
Query: 661 EILNEKLLKCFNVDCDGRIENVNVPSSYRCSACNKLNCMHCRTTHLDGETCDQWQINNKH 482
+ N C DC + + S + + + C + H C +++++
Sbjct: 255 KH-NRNYKWCPFADCKSIVHLRDTSSLPEYTRLHYSPFVKCNSFHRFCFNCG-FEVHSPA 312
Query: 481 XXXXXXXXXXXXXXXXXXXIAMY-----CVKCGTLCERDGGCYGVKCPICKTALCFITQK 317
+ C KC E++GGC + C CK C+I +
Sbjct: 313 DCKITTAWVKKARKESEILNWVLSHTKECPKCSVNIEKNGGCNHMVCSSCKYEFCWICE- 371
Query: 316 ARWGPQG 296
W P G
Sbjct: 372 GPWAPHG 378
>sp|Q22431|ARI2_CAEEL Probable ariadne-2 protein (Ari-2)
Length = 482
Score = 42.0 bits (97), Expect = 0.002
Identities = 37/180 (20%), Positives = 61/180 (33%), Gaps = 12/180 (6%)
Frame = -2
Query: 829 CGHKCCTSCFK----KKIAVNPFYPIECF--QCSQVLTDDECLKYFSSEQATKYLNSKTY 668
CGH C C+K +++ IEC +C + L + K +
Sbjct: 145 CGHCFCEHCWKSHVESRLSEGVASRIECMESECEVYAPSEFVLSIIKNSPVIKLKYERFL 204
Query: 667 LNEILNE--KLLKCFNVDCDGRIENVNV-PSSYRCSACNKLNCMHCRTTH---LDGETCD 506
L +++N L C +C I + V P C C+ C+ C + ET
Sbjct: 205 LRDMVNSHPHLKFCVGNECPVIIRSTEVKPKRVTCMQCHTSFCVKCGADYHAPTSCETIK 264
Query: 505 QWQINNKHXXXXXXXXXXXXXXXXXXXIAMYCVKCGTLCERDGGCYGVKCPICKTALCFI 326
QW C +C + E+ GGC ++C C+ C++
Sbjct: 265 QWMTK---------CADDSETANYISAHTKDCPQCHSCIEKAGGCNHIQCTRCRHHFCWM 315
>sp|O95376|ARI2_HUMAN Ariadne-2 protein homolog (ARI-2) (Triad1 protein)
Length = 493
Score = 39.3 bits (90), Expect = 0.014
Identities = 37/180 (20%), Positives = 65/180 (36%), Gaps = 12/180 (6%)
Frame = -2
Query: 829 CGHKCCTSCFKKKIAV----NPFYPIECF--QCSQVLTDDECLKYFSSEQATKYLNSKTY 668
C H+ C SC+++ +V + C C +D +E+ + +
Sbjct: 156 CQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQDCPLRTPEDFVFPLLPNEELREKYRRYLF 215
Query: 667 LNEILNEKLLK-CFNVDCDGRIENVNVPSSYR--CSACNKLNCMHCRTTH---LDGETCD 506
+ + + L+ C DC + V P + R C+ CN++ C CR + D T
Sbjct: 216 RDYVESHYQLQLCPGADCP-MVIRVQEPRARRVQCNRCNEVFCFKCRQMYHAPTDCATIR 274
Query: 505 QWQINNKHXXXXXXXXXXXXXXXXXXXIAMYCVKCGTLCERDGGCYGVKCPICKTALCFI 326
+W C KC E++GGC ++C CK C++
Sbjct: 275 KWLTK---------CADDSETANYISAHTKDCPKCNICIEKNGGCNHMQCSKCKHDFCWM 325
>sp|Q9Y4X5|ARI1_HUMAN Ariadne-1 protein homolog (ARI-1) (Ubiquitin-conjugating enzyme
E2-binding protein 1) (UbcH7-binding protein)
(UbcM4-interacting protein) (HHARI) (H7-AP2) (MOP-6)
Length = 557
Score = 38.1 bits (87), Expect = 0.030
Identities = 44/190 (23%), Positives = 62/190 (32%), Gaps = 12/190 (6%)
Frame = -2
Query: 829 CGHKCCTSCFKKKIAVNPF-----YPIEC-FQCSQVLTDDECLKYFSSEQATKYLNSKTY 668
CGHK C C+ + + I C +L DD + ++ K
Sbjct: 203 CGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDDNTVMRLITDSKVKLKYQHLI 262
Query: 667 LNEILN-EKLLK-CFNVDCDGRIENVNVPSS--YRCSACNKLNCMHCRTTHLDGETCDQW 500
N + +LLK C DC + V P + RC C + C +C D C +W
Sbjct: 263 TNSFVECNRLLKWCPAPDCH-HVVKVQYPDAKPVRCK-CGRQFCFNCGENWHDPVKC-KW 319
Query: 499 QINNKHXXXXXXXXXXXXXXXXXXXIAMYCVKCGTLCERDGGCYGVKC--PICKTALCFI 326
C KC E+DGGC + C CK C++
Sbjct: 320 L-----KKWIKKCDDDSETSNWIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWV 374
Query: 325 TQKARWGPQG 296
W P G
Sbjct: 375 C-LGPWEPHG 383
>sp|Q9Z1K5|ARI1_MOUSE Ariadne-1 protein homolog (ARI-1) (Ubiquitin-conjugating enzyme
E2-binding protein 1) (UbcH7-binding protein)
(UbcM4-interacting protein 77)
Length = 555
Score = 38.1 bits (87), Expect = 0.030
Identities = 44/190 (23%), Positives = 62/190 (32%), Gaps = 12/190 (6%)
Frame = -2
Query: 829 CGHKCCTSCFKKKIAVNPF-----YPIEC-FQCSQVLTDDECLKYFSSEQATKYLNSKTY 668
CGHK C C+ + + I C +L DD + ++ K
Sbjct: 201 CGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDDNTVMRLITDSKVKLKYQHLI 260
Query: 667 LNEILN-EKLLK-CFNVDCDGRIENVNVPSS--YRCSACNKLNCMHCRTTHLDGETCDQW 500
N + +LLK C DC + V P + RC C + C +C D C +W
Sbjct: 261 TNSFVECNRLLKWCPAPDCH-HVVKVQYPDAKPVRCK-CGRQFCFNCGENWHDPVKC-KW 317
Query: 499 QINNKHXXXXXXXXXXXXXXXXXXXIAMYCVKCGTLCERDGGCYGVKC--PICKTALCFI 326
C KC E+DGGC + C CK C++
Sbjct: 318 L-----KKWIKKCDDDSETSNWIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWV 372
Query: 325 TQKARWGPQG 296
W P G
Sbjct: 373 C-LGPWEPHG 381
>sp|Q04638|YMG8_YEAST Hypothetical 54.1 kDa protein in DAK1-ORC1 intergenic region
Length = 464
Score = 37.4 bits (85), Expect = 0.051
Identities = 14/29 (48%), Positives = 17/29 (58%)
Frame = -2
Query: 412 CVKCGTLCERDGGCYGVKCPICKTALCFI 326
C KC + ER GC +KC +C T CFI
Sbjct: 402 CPKCKVVVERSEGCNKMKCEVCGTLFCFI 430
>sp|Q9Z1K6|ARI2_MOUSE Ariadne-2 protein homolog (ARI-2) (Triad1 protein)
(UbcM4-interacting protein 48)
Length = 492
Score = 37.0 bits (84), Expect = 0.067
Identities = 37/180 (20%), Positives = 64/180 (35%), Gaps = 12/180 (6%)
Frame = -2
Query: 829 CGHKCCTSCFKKKIAV----NPFYPIECF--QCSQVLTDDECLKYFSSEQATKYLNSKTY 668
C H+ C SC+++ +V I C C +D +E+ +
Sbjct: 155 CQHQFCRSCWEQHCSVLVKDGVGVGISCMAQDCPLRTPEDFVFPLLPNEELRDKYRRYLF 214
Query: 667 LNEILNE-KLLKCFNVDCDGRIENVNVPSSYR--CSACNKLNCMHCRTTH---LDGETCD 506
+ + + +L C DC + V P + R C+ C+++ C CR + D T
Sbjct: 215 RDYVESHFQLQLCPGADCP-MVIRVQEPRARRVQCNRCSEVFCFKCRQMYHAPTDCATIR 273
Query: 505 QWQINNKHXXXXXXXXXXXXXXXXXXXIAMYCVKCGTLCERDGGCYGVKCPICKTALCFI 326
+W C KC E++GGC ++C CK C++
Sbjct: 274 KWLTK---------CADDSETANYISAHTKDCPKCNICIEKNGGCNHMQCSKCKHDFCWM 324
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 79,113,314
Number of Sequences: 369166
Number of extensions: 1485539
Number of successful extensions: 4969
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4659
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4958
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8100769320
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)