Planaria EST Database


DrC_02013

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_02013
         (890 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q9QY33|TSN3_MOUSE  Tetraspanin-3 (Tspan-3) (Transmembrane...    53   1e-06
sp|O60637|TSN3_HUMAN  Tetraspanin-3 (Tspan-3) (Transmembrane...    46   2e-04
sp|Q8QZY6|TSN14_MOUSE  Tetraspanin-14 (Tspan-14) (Transmembr...    46   2e-04
sp|Q8NG11|TSN14_HUMAN  Tetraspanin-14 (Tspan-14) (Transmembr...    45   2e-04
sp|P19331|IM23_SCHMA  23 kDa integral membrane protein (SM23)      44   8e-04
sp|Q9D7W4|TSN17_MOUSE  Tetraspanin-17 (Tspan-17) (Transmembr...    43   0.001
sp|Q96FV3|TSN17_HUMAN  Tetraspanin-17 (Tspan-17) (Transmembr...    43   0.001
sp|P27591|IM23_SCHJA  23 kDa integral membrane protein (SJ23)      42   0.002
sp|Q26499|IM23_SCHHA  23 kDa integral membrane protein (Sh23)      41   0.005
sp|Q7YQL0|TSN7_PANTR  Tetraspanin-7 (Tspan-7) (Transmembrane...    39   0.015
>sp|Q9QY33|TSN3_MOUSE Tetraspanin-3 (Tspan-3) (Transmembrane 4 superfamily member 8)
           (Tetraspanin TM4-A) (OSP-associated protein 1) (OAP-1)
          Length = 253

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 50/211 (23%), Positives = 97/211 (45%), Gaps = 20/211 (9%)
 Frame = +1

Query: 274 HIFI--DSLKHIF-NVHSVFGTMIIVALVVITISLSGLYCLYKNDYEKLGLQGASFLILL 444
           ++FI  D   H F +V+++F  ++I+A+  +   +  + C       + GL    F++LL
Sbjct: 33  YVFITYDDYDHFFEDVYTLFPAVVIIAVGALLFIIGLIGCCATIRESRCGLATFVFILLL 92

Query: 445 I-------VMIALIFTFWVEWEANAHFGMSYATQSYSPKMEDSRYLESIQKFLYCCGSRG 603
           +       V++  ++   VE E +      Y T + +     SR ++ +Q+ L+CCG   
Sbjct: 93  VFVTEVVVVVLGYVYRAKVENEVDRSIQKVYKTYNGTNSDAASRAIDYVQRQLHCCGIHN 152

Query: 604 PKDFDVANQY--FVRGMVPISCCNTIANSEICSKFAKQKGYLAINASYSFPIGC----MT 765
             D++  + +       VP+SCC   A S  C+      G LA N S  +  GC    + 
Sbjct: 153 YSDWENTDWFKETKNQSVPLSCCRETAKS--CN------GSLA-NPSDLYAEGCEALVVK 203

Query: 766 KLEKI----VWPSIVTVILNLSILSFICMII 846
           KL++I    +W ++    + L  +   C+++
Sbjct: 204 KLQEILMHVIWAALAFAAIQLLGMLCACIVL 234
>sp|O60637|TSN3_HUMAN Tetraspanin-3 (Tspan-3) (Transmembrane 4 superfamily member 8)
           (Tetraspanin TM4-A)
          Length = 253

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 48/213 (22%), Positives = 99/213 (46%), Gaps = 22/213 (10%)
 Frame = +1

Query: 274 HIFI--DSLKHIF-NVHSVFGTMIIVALVVITISLSGLYCLYKNDYEKLGLQGASFLILL 444
           ++FI  D   H F +V+++   ++I+A+  +   +  + C       + GL  A+F+I+L
Sbjct: 33  YVFITYDDYDHFFEDVYTLIPAVVIIAVGALLFIIGLIGCCATIRESRCGL--ATFVIIL 90

Query: 445 ---------IVMIALIFTFWVEWEANAHFGMSYATQSYSPKMEDSRYLESIQKFLYCCGS 597
                    +V++  ++   VE E +      Y T + +     SR ++ +Q+ L+CCG 
Sbjct: 91  LLVFVTEVVVVVLGYVYRAKVENEVDRSIQKVYKTYNGTNPDAASRAIDYVQRQLHCCGI 150

Query: 598 RGPKDFDVANQY--FVRGMVPISCCNTIANSEICSKFAKQKGYLAINASYSFPIGC---- 759
               D++  + +       VP+SCC   A++  C+      G LA + S  +  GC    
Sbjct: 151 HNYSDWENTDWFKETKNQSVPLSCCRETASN--CN------GSLA-HPSDLYAEGCEALV 201

Query: 760 MTKLEKI----VWPSIVTVILNLSILSFICMII 846
           + KL++I    +W ++    + L  +   C+++
Sbjct: 202 VKKLQEIMMHVIWAALAFAAIQLLGMLCACIVL 234
>sp|Q8QZY6|TSN14_MOUSE Tetraspanin-14 (Tspan-14) (Transmembrane 4 superfamily member 14)
          Length = 270

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 38/146 (26%), Positives = 66/146 (45%), Gaps = 18/146 (12%)
 Frame = +1

Query: 283 IDSLKHIFNVHSVFGTMII--VALVVITISLSGLY-------CLYKNDYEKLGLQGASFL 435
           +  L  +  +H +   +++  V +V+ T+  +G         CL K     + L    FL
Sbjct: 47  LSDLTKVTRLHGIDPVVLVLMVGVVMFTLGFAGCVGALRENICLLKFFCGAIVL--IFFL 104

Query: 436 ILLIVMIALIFTFWVEWEANAHFGMSYATQSYSPKMEDSRYLESIQKFLYCCGSRGPKDF 615
            L + ++A +F  WV       F  +   +SY   ++    ++S+QK   CCG+ GP+D+
Sbjct: 105 ELAVAVLAFLFQDWVRDRFREFFESNI--KSYRDDIDLQNLIDSLQKANQCCGAYGPEDW 162

Query: 616 DVANQYF---------VRGMVPISCC 666
           D+ N YF          +  VP SCC
Sbjct: 163 DL-NVYFNCSGASYSREKCGVPFSCC 187
>sp|Q8NG11|TSN14_HUMAN Tetraspanin-14 (Tspan-14) (Transmembrane 4 superfamily member 14)
           (DC-TM4F2)
          Length = 270

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 35/144 (24%), Positives = 65/144 (45%), Gaps = 16/144 (11%)
 Frame = +1

Query: 283 IDSLKHIFNVHSVFGTMII--VALVVITISLSGLYCLYKNDYEKLGLQGAS-----FLIL 441
           +  L  +  +H +   +++  V +V+ T+  +G     + +   L     +     FL L
Sbjct: 47  LSDLTKVTRMHGIDPVVLVLMVGVVMFTLGFAGCVGALRENICLLNFFCGTIVLIFFLEL 106

Query: 442 LIVMIALIFTFWVEWEANAHFGMSYATQSYSPKMEDSRYLESIQKFLYCCGSRGPKDFDV 621
            + ++A +F  WV       F  +   +SY   ++    ++S+QK   CCG+ GP+D+D+
Sbjct: 107 AVAVLAFLFQDWVRDRFREFFESNI--KSYRDDIDLQNLIDSLQKANQCCGAYGPEDWDL 164

Query: 622 ANQYF---------VRGMVPISCC 666
            N YF          +  VP SCC
Sbjct: 165 -NVYFNCSGASYSREKCGVPFSCC 187
>sp|P19331|IM23_SCHMA 23 kDa integral membrane protein (SM23)
          Length = 218

 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 33/128 (25%), Positives = 62/128 (48%), Gaps = 9/128 (7%)
 Frame = +1

Query: 307 NVHSVFGT----MIIVALVVITISLSGLYCLYKNDYEKLGLQGASFLILLIV-----MIA 459
           N+H V+      +I+V ++++ +S  G     K +   L +     ++LLI      ++A
Sbjct: 46  NLHKVWQAAPIAIIVVGVIILIVSFLGCCGAIKENVCMLYMYAFFLVVLLIAELAAAIVA 105

Query: 460 LIFTFWVEWEANAHFGMSYATQSYSPKMEDSRYLESIQKFLYCCGSRGPKDFDVANQYFV 639
           +++   ++ E +A   M+ A     P  E + ++  IQ   +CCG++GP D+        
Sbjct: 106 VVYKDRIDSEIDAL--MTGALDK--PTKEITEFMNLIQSSFHCCGAKGPDDY-------- 153

Query: 640 RGMVPISC 663
           RG VP SC
Sbjct: 154 RGNVPASC 161
>sp|Q9D7W4|TSN17_MOUSE Tetraspanin-17 (Tspan-17) (Transmembrane 4 superfamily member 17)
           (Tetraspan protein SB134) (F-box only protein 23)
          Length = 270

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 35/139 (25%), Positives = 64/139 (46%), Gaps = 14/139 (10%)
 Frame = +1

Query: 430 FLILLIVMIALIFTFWVEWEANAHFGMSYATQSYSPKMEDSRYLESIQKFLYCCGSRGPK 609
           FL L   ++A +F  W+  + N     +   ++Y   ++    ++  Q++  CCG+RGP 
Sbjct: 105 FLELAAGILAFVFKDWIRDQLNLFINNN--VKAYRDDLDLQNLIDFAQEYWSCCGARGPN 162

Query: 610 DFDVANQYF---------VRGMVPISCC-----NTIANSEICSKFAKQKGYLAINASYSF 747
           D+++ N YF          R  VP SCC       + N++ C    + K  L    S  +
Sbjct: 163 DWNL-NIYFNCTDLNPSRERCGVPFSCCVRDPAEDVLNTQ-CGYDIRLKLELEQEGSI-Y 219

Query: 748 PIGCMTKLEKIVWPSIVTV 804
             GC+ + EK +  +++ V
Sbjct: 220 TKGCVGQFEKWLQDNLIVV 238
>sp|Q96FV3|TSN17_HUMAN Tetraspanin-17 (Tspan-17) (Transmembrane 4 superfamily member 17)
           (Tetraspan protein SB134) (F-box only protein 23)
          Length = 263

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 35/144 (24%), Positives = 65/144 (45%), Gaps = 19/144 (13%)
 Frame = +1

Query: 430 FLILLIVMIALIFTFWVEWEANAHFGMSYATQSYSPKMEDSRYLESIQKFLYCCGSRGPK 609
           FL L   ++A +F  W+  + N     +   ++Y   ++    ++  Q++  CCG+RGP 
Sbjct: 105 FLELATGILAFVFKDWIRDQLNLFINNN--VKAYRDDIDLQNLIDFAQEYWSCCGARGPN 162

Query: 610 DFDVANQYF---------VRGMVPISCC---------NTIANSEICSKF-AKQKGYLAIN 732
           D+++ N YF          R  VP SCC         NT    ++  K   +Q+G++   
Sbjct: 163 DWNL-NIYFNCTDLNPSRERCGVPFSCCVRDPAEDVLNTQCGYDVRLKLELEQQGFIHTK 221

Query: 733 ASYSFPIGCMTKLEKIVWPSIVTV 804
                  GC+ + EK +  +++ V
Sbjct: 222 -------GCVGQFEKWLQDNLIVV 238
>sp|P27591|IM23_SCHJA 23 kDa integral membrane protein (SJ23)
          Length = 218

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 33/128 (25%), Positives = 62/128 (48%), Gaps = 9/128 (7%)
 Frame = +1

Query: 307 NVHSVFGT----MIIVALVVITISLSGLYCLYKNDYEKLGLQGASFLILLIV-----MIA 459
           N+H V+      +I+V +V++ +S  G     K +   L +     ++LLI      ++A
Sbjct: 46  NLHKVWQAAPIAIIVVGVVILIVSFLGCCGAIKENVCMLYMYAFFLIVLLIAELVAAIVA 105

Query: 460 LIFTFWVEWEANAHFGMSYATQSYSPKMEDSRYLESIQKFLYCCGSRGPKDFDVANQYFV 639
           +++   ++ E N    M+ A ++  P  E +  ++ IQ   +CCG +GP D+        
Sbjct: 106 VVYKDKIDDEINTL--MTGALEN--PNEEITATMDKIQTSFHCCGVKGPDDY-------- 153

Query: 640 RGMVPISC 663
           +G VP SC
Sbjct: 154 KGNVPASC 161
>sp|Q26499|IM23_SCHHA 23 kDa integral membrane protein (Sh23)
          Length = 218

 Score = 40.8 bits (94), Expect = 0.005
 Identities = 27/112 (24%), Positives = 60/112 (53%), Gaps = 9/112 (8%)
 Frame = +1

Query: 307 NVHSVFGT----MIIVALVVITISLSGLYCLYKNDYEKLGLQGASFLILLIV-----MIA 459
           N+H V+      +I+V ++++ +S  G     K +   L +     +ILLI      ++A
Sbjct: 46  NLHKVWQAAPIAIIVVGVIILIVSFLGCCGAIKENVCMLYMYAFFLIILLIAELAAAIVA 105

Query: 460 LIFTFWVEWEANAHFGMSYATQSYSPKMEDSRYLESIQKFLYCCGSRGPKDF 615
           +++   ++ E +A   M+ A    +P++ +  +++ IQ   +CCG++GP+D+
Sbjct: 106 VVYKDRIDSEIDAL--MTGALDKPTPEITE--FMDLIQSSFHCCGAKGPQDY 153
>sp|Q7YQL0|TSN7_PANTR Tetraspanin-7 (Tspan-7) (Transmembrane 4 superfamily member 2)
          Length = 244

 Score = 39.3 bits (90), Expect = 0.015
 Identities = 25/80 (31%), Positives = 41/80 (51%), Gaps = 2/80 (2%)
 Frame = +1

Query: 433 LILLIVMIALIFTFWVEWEANAHFGMSY--ATQSYSPKMEDSRYLESIQKFLYCCGSRGP 606
           L+ L  ++A I  F    E    F  +Y  A Q+Y+   E SR ++ +Q+ L CCG +  
Sbjct: 92  LVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQTYNGNDERSRAVDHVQRSLSCCGVQNY 151

Query: 607 KDFDVANQYFVRGMVPISCC 666
            ++   + YF+   +P SCC
Sbjct: 152 TNWS-TSPYFLEHGIPPSCC 170
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 94,390,139
Number of Sequences: 369166
Number of extensions: 1874319
Number of successful extensions: 4621
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4482
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4618
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8934348180
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)