Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_01974 (175 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q13627|DYR1A_HUMAN Dual specificity tyrosine-phosphoryla... 43 3e-04 sp|Q61214|DYR1A_MOUSE Dual specificity tyrosine-phosphoryla... 43 3e-04 sp|Q63470|DYR1A_RAT Dual specificity tyrosine-phosphorylati... 43 3e-04 sp|Q9Y463|DYR1B_HUMAN Dual specificity tyrosine-phosphoryla... 42 3e-04 sp|Q9Z188|DYR1B_MOUSE Dual specificity tyrosine-phosphoryla... 42 3e-04 sp|Q6C3J2|IPL1_YARLI Spindle assembly checkpoint kinase (Au... 42 3e-04 sp|Q96NX5|KCC1G_HUMAN Calcium/calmodulin-dependent protein ... 42 6e-04 sp|Q09147|FGFR2_DROME Fibroblast growth factor receptor hom... 42 6e-04 sp|Q91VB2|KCC1G_MOUSE Calcium/calmodulin-dependent protein ... 41 7e-04 sp|O70150|KCC1B_RAT Calcium/calmodulin-dependent protein ki... 41 7e-04
>sp|Q13627|DYR1A_HUMAN Dual specificity tyrosine-phosphorylation regulated kinase 1A (Protein kinase minibrain homolog) (MNBH) (HP86) (Dual specificity YAK1-related kinase) Length = 763 Score = 42.7 bits (99), Expect = 3e-04 Identities = 20/50 (40%), Positives = 31/50 (62%) Frame = +1 Query: 13 IYKYTDRVLAYVAPEILEGKPFDSSVDVWSLGVIMIEIDTHGQLYPKLTE 162 IY+Y Y +PE+L G P+D ++D+WSLG I++E+ T L+ E Sbjct: 318 IYQYIQSRF-YRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANE 366
>sp|Q61214|DYR1A_MOUSE Dual specificity tyrosine-phosphorylation regulated kinase 1A (Protein kinase minibrain homolog) (MNBH) (MP86) (Dual specificity YAK1-related kinase) Length = 763 Score = 42.7 bits (99), Expect = 3e-04 Identities = 20/50 (40%), Positives = 31/50 (62%) Frame = +1 Query: 13 IYKYTDRVLAYVAPEILEGKPFDSSVDVWSLGVIMIEIDTHGQLYPKLTE 162 IY+Y Y +PE+L G P+D ++D+WSLG I++E+ T L+ E Sbjct: 318 IYQYIQSRF-YRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANE 366
>sp|Q63470|DYR1A_RAT Dual specificity tyrosine-phosphorylation regulated kinase 1A (Protein kinase minibrain homolog) (MNBH) (RP86) (Dual specificity YAK1-related kinase) Length = 763 Score = 42.7 bits (99), Expect = 3e-04 Identities = 20/50 (40%), Positives = 31/50 (62%) Frame = +1 Query: 13 IYKYTDRVLAYVAPEILEGKPFDSSVDVWSLGVIMIEIDTHGQLYPKLTE 162 IY+Y Y +PE+L G P+D ++D+WSLG I++E+ T L+ E Sbjct: 318 IYQYIQSRF-YRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANE 366
>sp|Q9Y463|DYR1B_HUMAN Dual specificity tyrosine-phosphorylation regulated kinase 1B (Mirk protein kinase) (Minibrain-related kinase) Length = 629 Score = 42.4 bits (98), Expect = 3e-04 Identities = 19/45 (42%), Positives = 30/45 (66%) Frame = +1 Query: 13 IYKYTDRVLAYVAPEILEGKPFDSSVDVWSLGVIMIEIDTHGQLY 147 IY+Y Y +PE+L G P+D ++D+WSLG I++E+ T L+ Sbjct: 270 IYQYIQSRF-YRSPEVLLGTPYDLAIDMWSLGCILVEMHTGEPLF 313
>sp|Q9Z188|DYR1B_MOUSE Dual specificity tyrosine-phosphorylation regulated kinase 1B Length = 589 Score = 42.4 bits (98), Expect = 3e-04 Identities = 19/45 (42%), Positives = 30/45 (66%) Frame = +1 Query: 13 IYKYTDRVLAYVAPEILEGKPFDSSVDVWSLGVIMIEIDTHGQLY 147 IY+Y Y +PE+L G P+D ++D+WSLG I++E+ T L+ Sbjct: 270 IYQYIQSRF-YRSPEVLLGTPYDLAIDMWSLGCILVEMHTGEPLF 313
>sp|Q6C3J2|IPL1_YARLI Spindle assembly checkpoint kinase (Aurora kinase) Length = 371 Score = 42.4 bits (98), Expect = 3e-04 Identities = 15/27 (55%), Positives = 23/27 (85%) Frame = +1 Query: 43 YVAPEILEGKPFDSSVDVWSLGVIMIE 123 Y+ PEI++ +P+D +VDVWSLG++M E Sbjct: 261 YLPPEIVQSRPYDKNVDVWSLGILMYE 287
>sp|Q96NX5|KCC1G_HUMAN Calcium/calmodulin-dependent protein kinase type 1G (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 476 Score = 41.6 bits (96), Expect = 6e-04 Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 9/63 (14%) Frame = +1 Query: 1 DDNGIYKYTDRVLAYVAPEILEGKPFDSSVDVWSLGVIMIEI---------DTHGQLYPK 153 + NGI YVAPE+L KP+ +VD WS+GVI + +T +L+ K Sbjct: 171 EQNGIMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVITYILLCGYPPFYEETESKLFEK 230 Query: 154 LTE 162 + E Sbjct: 231 IKE 233
>sp|Q09147|FGFR2_DROME Fibroblast growth factor receptor homolog 2 precursor (Breathless protein) (dFGF-R1) Length = 1052 Score = 41.6 bits (96), Expect = 6e-04 Identities = 20/41 (48%), Positives = 29/41 (70%), Gaps = 1/41 (2%) Frame = +1 Query: 37 LAYVAPEILEGKPFDSSVDVWSLGVIMIEIDTHG-QLYPKL 156 + ++APE L+ K +DS DVWS GV++ EI T+G Q YP + Sbjct: 905 IKWMAPESLQEKKYDSQSDVWSYGVLLWEIMTYGDQPYPHI 945
>sp|Q91VB2|KCC1G_MOUSE Calcium/calmodulin-dependent protein kinase type 1G (CaM kinase IG) (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III) Length = 477 Score = 41.2 bits (95), Expect = 7e-04 Identities = 21/63 (33%), Positives = 32/63 (50%), Gaps = 9/63 (14%) Frame = +1 Query: 1 DDNGIYKYTDRVLAYVAPEILEGKPFDSSVDVWSLGVIMIEI---------DTHGQLYPK 153 + NG+ YVAPE+L KP+ +VD WS+GVI + +T +L+ K Sbjct: 171 EQNGVMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVITYILLCGYPPFYEETESKLFEK 230 Query: 154 LTE 162 + E Sbjct: 231 IKE 233
>sp|O70150|KCC1B_RAT Calcium/calmodulin-dependent protein kinase type 1B (CaM kinase IB) (CaM kinase I beta) (CaMKI-beta) (CaM-KI beta) (Pregnancy up-regulated non-ubiquitously expressed CaM kinase homolog) Length = 343 Score = 41.2 bits (95), Expect = 7e-04 Identities = 17/24 (70%), Positives = 21/24 (87%) Frame = +1 Query: 43 YVAPEILEGKPFDSSVDVWSLGVI 114 YVAPE+LE KP+ +VDVW+LGVI Sbjct: 178 YVAPELLEQKPYGKAVDVWALGVI 201
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.317 0.141 0.420 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 21,912,376 Number of Sequences: 369166 Number of extensions: 348520 Number of successful extensions: 2351 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 2259 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 2305 length of database: 68,354,980 effective HSP length: 30 effective length of database: 62,812,930 effective search space used: 1695949110 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits)