Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_01897 (568 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q969X1|TMBI1_HUMAN Transmembrane BAX inhibitor motif-con... 78 1e-14 sp|Q8BJZ3|TMBI1_MOUSE Transmembrane BAX inhibitor motif-con... 78 2e-14 sp|O88407|FAIM2_RAT Fas apoptotic inhibitory molecule 2 (Li... 72 7e-13 sp|Q9BWQ8|FAIM2_HUMAN Fas apoptotic inhibitory molecule 2 (... 72 1e-12 sp|Q8K097|FAIM2_MOUSE Fas apoptotic inhibitory molecule 2 (... 72 1e-12 sp|Q9HC24|TMBI4_HUMAN Transmembrane BAX inhibitor motif-con... 50 4e-06 sp|Q9DA39|TMBI4_MOUSE Transmembrane BAX inhibitor motif-con... 50 5e-06 sp|Q9ZKT1|Y920_HELPJ Hypothetical protein JHP0854 48 1e-05 sp|O25578|Y920_HELPY Hypothetical protein HP0920 48 1e-05 sp|P48558|YN45_YEAST Hypothetical 33.6 kDa protein in MCK1-... 47 3e-05
>sp|Q969X1|TMBI1_HUMAN Transmembrane BAX inhibitor motif-containing protein 1 (RECS1 protein homolog) Length = 311 Score = 78.2 bits (191), Expect = 1e-14 Identities = 37/73 (50%), Positives = 50/73 (68%) Frame = +1 Query: 76 IYLTMGYSKVLHGVYAGLCILVFGIYLIYDTQLVIGGRKYELSPEDYIEGALQLYLDIVN 255 I L Y LH +YA L + F ++L YDTQLV+G RK+ +SPEDYI GALQ+Y DI+ Sbjct: 239 IVLYFQYVYWLHMLYAALGAICFTLFLAYDTQLVLGNRKHTISPEDYITGALQIYTDIIY 298 Query: 256 MFLIILSLFGNKN 294 +F +L L G++N Sbjct: 299 IFTFVLQLMGDRN 311
>sp|Q8BJZ3|TMBI1_MOUSE Transmembrane BAX inhibitor motif-containing protein 1 (RECS1 protein) (Responsive to centrifugal force and shear stress gene 1 protein) Length = 309 Score = 77.8 bits (190), Expect = 2e-14 Identities = 38/73 (52%), Positives = 50/73 (68%) Frame = +1 Query: 76 IYLTMGYSKVLHGVYAGLCILVFGIYLIYDTQLVIGGRKYELSPEDYIEGALQLYLDIVN 255 I L Y LH VYA L + F ++L YDTQLV+G RK+ +SPEDYI GALQ+Y DIV Sbjct: 237 IVLIFKYIYWLHMVYAALGAICFTLFLAYDTQLVLGNRKHTISPEDYITGALQIYTDIVY 296 Query: 256 MFLIILSLFGNKN 294 +F +L L G+++ Sbjct: 297 IFTFVLQLVGSRD 309
>sp|O88407|FAIM2_RAT Fas apoptotic inhibitory molecule 2 (Lifeguard protein) (Neural membrane protein 35) Length = 316 Score = 72.4 bits (176), Expect = 7e-13 Identities = 36/72 (50%), Positives = 48/72 (66%) Frame = +1 Query: 70 MIIYLTMGYSKVLHGVYAGLCILVFGIYLIYDTQLVIGGRKYELSPEDYIEGALQLYLDI 249 + I L Y LH VYA L VF ++L +DTQL++G R++ LSPE+YI GAL +YLDI Sbjct: 241 LAILLPFQYVPWLHAVYAVLGAGVFTLFLAFDTQLLMGNRRHSLSPEEYIFGALNIYLDI 300 Query: 250 VNMFLIILSLFG 285 + +F L LFG Sbjct: 301 IYIFTFFLQLFG 312
>sp|Q9BWQ8|FAIM2_HUMAN Fas apoptotic inhibitory molecule 2 (Lifeguard protein) (Transmembrane BAX inhibitor motif-containing protein 2) Length = 316 Score = 72.0 bits (175), Expect = 1e-12 Identities = 36/72 (50%), Positives = 47/72 (65%) Frame = +1 Query: 70 MIIYLTMGYSKVLHGVYAGLCILVFGIYLIYDTQLVIGGRKYELSPEDYIEGALQLYLDI 249 + I L Y LH VYA L VF ++L DTQL++G R++ LSPE+YI GAL +YLDI Sbjct: 241 LAILLPFQYVPWLHAVYAALGAGVFTLFLALDTQLLMGNRRHSLSPEEYIFGALNIYLDI 300 Query: 250 VNMFLIILSLFG 285 + +F L LFG Sbjct: 301 IYIFTFFLQLFG 312
>sp|Q8K097|FAIM2_MOUSE Fas apoptotic inhibitory molecule 2 (Lifeguard protein) Length = 317 Score = 72.0 bits (175), Expect = 1e-12 Identities = 35/72 (48%), Positives = 48/72 (66%) Frame = +1 Query: 70 MIIYLTMGYSKVLHGVYAGLCILVFGIYLIYDTQLVIGGRKYELSPEDYIEGALQLYLDI 249 + + L Y LH VYA L VF ++L +DTQL++G R++ LSPE+YI GAL +YLDI Sbjct: 242 LAVLLPFQYVPWLHAVYAVLGAGVFTLFLAFDTQLLMGNRRHSLSPEEYIFGALNIYLDI 301 Query: 250 VNMFLIILSLFG 285 + +F L LFG Sbjct: 302 IYIFTFFLQLFG 313
>sp|Q9HC24|TMBI4_HUMAN Transmembrane BAX inhibitor motif-containing protein 4 (Z-protein) (S1R protein) Length = 238 Score = 50.1 bits (118), Expect = 4e-06 Identities = 25/60 (41%), Positives = 41/60 (68%) Frame = +1 Query: 94 YSKVLHGVYAGLCILVFGIYLIYDTQLVIGGRKYELSPEDYIEGALQLYLDIVNMFLIIL 273 YS+++ V A L+F ++IYDT ++ ++LSPE+Y+ A+ LYLDI+N+FL +L Sbjct: 174 YSEIMELVLAAAGALLFCGFIIYDTHSLM----HKLSPEEYVLAAISLYLDIINLFLHLL 229
>sp|Q9DA39|TMBI4_MOUSE Transmembrane BAX inhibitor motif-containing protein 4 (Z-protein) Length = 238 Score = 49.7 bits (117), Expect = 5e-06 Identities = 25/60 (41%), Positives = 40/60 (66%) Frame = +1 Query: 94 YSKVLHGVYAGLCILVFGIYLIYDTQLVIGGRKYELSPEDYIEGALQLYLDIVNMFLIIL 273 YS+ + V A L L+F ++IYDT ++ + LSPE+Y+ A+ LY+DI+N+FL +L Sbjct: 174 YSETMELVLASLGALLFCGFIIYDTHSLM----HRLSPEEYVIAAISLYMDIINLFLHLL 229
>sp|Q9ZKT1|Y920_HELPJ Hypothetical protein JHP0854 Length = 230 Score = 48.1 bits (113), Expect = 1e-05 Identities = 29/73 (39%), Positives = 45/73 (61%) Frame = +1 Query: 67 CMIIYLTMGYSKVLHGVYAGLCILVFGIYLIYDTQLVIGGRKYELSPEDYIEGALQLYLD 246 C +I L +G S + V AG ++F +Y+ YDTQ ++ G Y+ SP I+ A+ LYLD Sbjct: 157 CSLINLFLG-SPMFQVVIAGASAILFSLYIAYDTQNIVKGM-YD-SP---IDAAVSLYLD 210 Query: 247 IVNMFLIILSLFG 285 +N+F+ IL + G Sbjct: 211 FLNVFISILQIIG 223
>sp|O25578|Y920_HELPY Hypothetical protein HP0920 Length = 230 Score = 48.1 bits (113), Expect = 1e-05 Identities = 29/73 (39%), Positives = 45/73 (61%) Frame = +1 Query: 67 CMIIYLTMGYSKVLHGVYAGLCILVFGIYLIYDTQLVIGGRKYELSPEDYIEGALQLYLD 246 C +I L +G S + V AG ++F +Y+ YDTQ ++ G Y+ SP I+ A+ LYLD Sbjct: 157 CSLINLFLG-SPMFQVVIAGASAILFSLYIAYDTQNIVKGM-YD-SP---IDAAVSLYLD 210 Query: 247 IVNMFLIILSLFG 285 +N+F+ IL + G Sbjct: 211 FLNVFISILQIIG 223
>sp|P48558|YN45_YEAST Hypothetical 33.6 kDa protein in MCK1-RPS19B intergenic region Length = 297 Score = 47.4 bits (111), Expect = 3e-05 Identities = 29/83 (34%), Positives = 44/83 (53%), Gaps = 10/83 (12%) Frame = +1 Query: 76 IYLTMGYSKVLHG----------VYAGLCILVFGIYLIYDTQLVIGGRKYELSPEDYIEG 225 I + MG + +L G +Y L ++F YL DTQL+ ++ P++ + Sbjct: 216 IMIGMGLTALLFGWNTHSSKFNLLYGWLGAILFTAYLFIDTQLIFR----KVYPDEEVRC 271 Query: 226 ALQLYLDIVNMFLIILSLFGNKN 294 A+ LYLDIVN+FL IL + N N Sbjct: 272 AMMLYLDIVNLFLSILRILANSN 294
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 64,163,832 Number of Sequences: 369166 Number of extensions: 1285992 Number of successful extensions: 2435 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 2403 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 2429 length of database: 68,354,980 effective HSP length: 104 effective length of database: 49,142,540 effective search space used: 4127973360 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)