Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_011_L20
(568 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q969X1|TMBI1_HUMAN Transmembrane BAX inhibitor motif-con... 78 1e-14
sp|Q8BJZ3|TMBI1_MOUSE Transmembrane BAX inhibitor motif-con... 78 2e-14
sp|O88407|FAIM2_RAT Fas apoptotic inhibitory molecule 2 (Li... 72 7e-13
sp|Q9BWQ8|FAIM2_HUMAN Fas apoptotic inhibitory molecule 2 (... 72 1e-12
sp|Q8K097|FAIM2_MOUSE Fas apoptotic inhibitory molecule 2 (... 72 1e-12
sp|Q9HC24|TMBI4_HUMAN Transmembrane BAX inhibitor motif-con... 50 4e-06
sp|Q9DA39|TMBI4_MOUSE Transmembrane BAX inhibitor motif-con... 50 5e-06
sp|Q9ZKT1|Y920_HELPJ Hypothetical protein JHP0854 48 1e-05
sp|O25578|Y920_HELPY Hypothetical protein HP0920 48 1e-05
sp|P48558|YN45_YEAST Hypothetical 33.6 kDa protein in MCK1-... 47 3e-05
>sp|Q969X1|TMBI1_HUMAN Transmembrane BAX inhibitor motif-containing protein 1 (RECS1
protein homolog)
Length = 311
Score = 78.2 bits (191), Expect = 1e-14
Identities = 37/73 (50%), Positives = 50/73 (68%)
Frame = +1
Query: 76 IYLTMGYSKVLHGVYAGLCILVFGIYLIYDTQLVIGGRKYELSPEDYIEGALQLYLDIVN 255
I L Y LH +YA L + F ++L YDTQLV+G RK+ +SPEDYI GALQ+Y DI+
Sbjct: 239 IVLYFQYVYWLHMLYAALGAICFTLFLAYDTQLVLGNRKHTISPEDYITGALQIYTDIIY 298
Query: 256 MFLIILSLFGNKN 294
+F +L L G++N
Sbjct: 299 IFTFVLQLMGDRN 311
>sp|Q8BJZ3|TMBI1_MOUSE Transmembrane BAX inhibitor motif-containing protein 1 (RECS1
protein) (Responsive to centrifugal force and shear
stress gene 1 protein)
Length = 309
Score = 77.8 bits (190), Expect = 2e-14
Identities = 38/73 (52%), Positives = 50/73 (68%)
Frame = +1
Query: 76 IYLTMGYSKVLHGVYAGLCILVFGIYLIYDTQLVIGGRKYELSPEDYIEGALQLYLDIVN 255
I L Y LH VYA L + F ++L YDTQLV+G RK+ +SPEDYI GALQ+Y DIV
Sbjct: 237 IVLIFKYIYWLHMVYAALGAICFTLFLAYDTQLVLGNRKHTISPEDYITGALQIYTDIVY 296
Query: 256 MFLIILSLFGNKN 294
+F +L L G+++
Sbjct: 297 IFTFVLQLVGSRD 309
>sp|O88407|FAIM2_RAT Fas apoptotic inhibitory molecule 2 (Lifeguard protein) (Neural
membrane protein 35)
Length = 316
Score = 72.4 bits (176), Expect = 7e-13
Identities = 36/72 (50%), Positives = 48/72 (66%)
Frame = +1
Query: 70 MIIYLTMGYSKVLHGVYAGLCILVFGIYLIYDTQLVIGGRKYELSPEDYIEGALQLYLDI 249
+ I L Y LH VYA L VF ++L +DTQL++G R++ LSPE+YI GAL +YLDI
Sbjct: 241 LAILLPFQYVPWLHAVYAVLGAGVFTLFLAFDTQLLMGNRRHSLSPEEYIFGALNIYLDI 300
Query: 250 VNMFLIILSLFG 285
+ +F L LFG
Sbjct: 301 IYIFTFFLQLFG 312
>sp|Q9BWQ8|FAIM2_HUMAN Fas apoptotic inhibitory molecule 2 (Lifeguard protein)
(Transmembrane BAX inhibitor motif-containing protein 2)
Length = 316
Score = 72.0 bits (175), Expect = 1e-12
Identities = 36/72 (50%), Positives = 47/72 (65%)
Frame = +1
Query: 70 MIIYLTMGYSKVLHGVYAGLCILVFGIYLIYDTQLVIGGRKYELSPEDYIEGALQLYLDI 249
+ I L Y LH VYA L VF ++L DTQL++G R++ LSPE+YI GAL +YLDI
Sbjct: 241 LAILLPFQYVPWLHAVYAALGAGVFTLFLALDTQLLMGNRRHSLSPEEYIFGALNIYLDI 300
Query: 250 VNMFLIILSLFG 285
+ +F L LFG
Sbjct: 301 IYIFTFFLQLFG 312
>sp|Q8K097|FAIM2_MOUSE Fas apoptotic inhibitory molecule 2 (Lifeguard protein)
Length = 317
Score = 72.0 bits (175), Expect = 1e-12
Identities = 35/72 (48%), Positives = 48/72 (66%)
Frame = +1
Query: 70 MIIYLTMGYSKVLHGVYAGLCILVFGIYLIYDTQLVIGGRKYELSPEDYIEGALQLYLDI 249
+ + L Y LH VYA L VF ++L +DTQL++G R++ LSPE+YI GAL +YLDI
Sbjct: 242 LAVLLPFQYVPWLHAVYAVLGAGVFTLFLAFDTQLLMGNRRHSLSPEEYIFGALNIYLDI 301
Query: 250 VNMFLIILSLFG 285
+ +F L LFG
Sbjct: 302 IYIFTFFLQLFG 313
>sp|Q9HC24|TMBI4_HUMAN Transmembrane BAX inhibitor motif-containing protein 4 (Z-protein)
(S1R protein)
Length = 238
Score = 50.1 bits (118), Expect = 4e-06
Identities = 25/60 (41%), Positives = 41/60 (68%)
Frame = +1
Query: 94 YSKVLHGVYAGLCILVFGIYLIYDTQLVIGGRKYELSPEDYIEGALQLYLDIVNMFLIIL 273
YS+++ V A L+F ++IYDT ++ ++LSPE+Y+ A+ LYLDI+N+FL +L
Sbjct: 174 YSEIMELVLAAAGALLFCGFIIYDTHSLM----HKLSPEEYVLAAISLYLDIINLFLHLL 229
>sp|Q9DA39|TMBI4_MOUSE Transmembrane BAX inhibitor motif-containing protein 4 (Z-protein)
Length = 238
Score = 49.7 bits (117), Expect = 5e-06
Identities = 25/60 (41%), Positives = 40/60 (66%)
Frame = +1
Query: 94 YSKVLHGVYAGLCILVFGIYLIYDTQLVIGGRKYELSPEDYIEGALQLYLDIVNMFLIIL 273
YS+ + V A L L+F ++IYDT ++ + LSPE+Y+ A+ LY+DI+N+FL +L
Sbjct: 174 YSETMELVLASLGALLFCGFIIYDTHSLM----HRLSPEEYVIAAISLYMDIINLFLHLL 229
>sp|Q9ZKT1|Y920_HELPJ Hypothetical protein JHP0854
Length = 230
Score = 48.1 bits (113), Expect = 1e-05
Identities = 29/73 (39%), Positives = 45/73 (61%)
Frame = +1
Query: 67 CMIIYLTMGYSKVLHGVYAGLCILVFGIYLIYDTQLVIGGRKYELSPEDYIEGALQLYLD 246
C +I L +G S + V AG ++F +Y+ YDTQ ++ G Y+ SP I+ A+ LYLD
Sbjct: 157 CSLINLFLG-SPMFQVVIAGASAILFSLYIAYDTQNIVKGM-YD-SP---IDAAVSLYLD 210
Query: 247 IVNMFLIILSLFG 285
+N+F+ IL + G
Sbjct: 211 FLNVFISILQIIG 223
>sp|O25578|Y920_HELPY Hypothetical protein HP0920
Length = 230
Score = 48.1 bits (113), Expect = 1e-05
Identities = 29/73 (39%), Positives = 45/73 (61%)
Frame = +1
Query: 67 CMIIYLTMGYSKVLHGVYAGLCILVFGIYLIYDTQLVIGGRKYELSPEDYIEGALQLYLD 246
C +I L +G S + V AG ++F +Y+ YDTQ ++ G Y+ SP I+ A+ LYLD
Sbjct: 157 CSLINLFLG-SPMFQVVIAGASAILFSLYIAYDTQNIVKGM-YD-SP---IDAAVSLYLD 210
Query: 247 IVNMFLIILSLFG 285
+N+F+ IL + G
Sbjct: 211 FLNVFISILQIIG 223
>sp|P48558|YN45_YEAST Hypothetical 33.6 kDa protein in MCK1-RPS19B intergenic region
Length = 297
Score = 47.4 bits (111), Expect = 3e-05
Identities = 29/83 (34%), Positives = 44/83 (53%), Gaps = 10/83 (12%)
Frame = +1
Query: 76 IYLTMGYSKVLHG----------VYAGLCILVFGIYLIYDTQLVIGGRKYELSPEDYIEG 225
I + MG + +L G +Y L ++F YL DTQL+ ++ P++ +
Sbjct: 216 IMIGMGLTALLFGWNTHSSKFNLLYGWLGAILFTAYLFIDTQLIFR----KVYPDEEVRC 271
Query: 226 ALQLYLDIVNMFLIILSLFGNKN 294
A+ LYLDIVN+FL IL + N N
Sbjct: 272 AMMLYLDIVNLFLSILRILANSN 294
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 64,163,832
Number of Sequences: 369166
Number of extensions: 1285992
Number of successful extensions: 2435
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2403
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2429
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 4127973360
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)