Planaria EST Database


DrC_01882

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_01882
         (903 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q8MJU1|CASP3_FELCA  Caspase-3 precursor (CASP-3) [Contain...   197   4e-50
sp|P42574|CASP3_HUMAN  Caspase-3 precursor (CASP-3) (Apopain...   194   3e-49
sp|Q5IS54|CASP3_PANTR  Caspase-3 precursor (CASP-3) [Contain...   194   3e-49
sp|Q8MKI5|CASP3_CANFA  Caspase-3 precursor (CASP-3) [Contain...   193   6e-49
sp|Q60431|CASP3_CRILO  Caspase-3 precursor (CASP-3) (Apopain...   191   2e-48
sp|P70677|CASP3_MOUSE  Caspase-3 precursor (CASP-3) (Apopain...   189   9e-48
sp|Q8MJC3|CASP3_RABIT  Caspase-3 precursor (CASP-3) (Apopain...   188   2e-47
sp|P55213|CASP3_RAT  Caspase-3 precursor (CASP-3) (Apopain) ...   188   2e-47
sp|Q95ND5|CASP3_PIG  Caspase-3 precursor (CASP-3) [Contains:...   187   3e-47
sp|P55214|CASP7_MESAU  Caspase-7 precursor (CASP-7) (ICE-lik...   171   3e-42
>sp|Q8MJU1|CASP3_FELCA Caspase-3 precursor (CASP-3) [Contains: Caspase-3 p17 subunit;
           Caspase-3 p12 subunit]
          Length = 277

 Score =  197 bits (500), Expect = 4e-50
 Identities = 97/236 (41%), Positives = 139/236 (58%), Gaps = 2/236 (0%)
 Frame = +3

Query: 108 DVSKIKLCYIINNEEFYTKLNLPKRLGTDEDFKRLKQVFTKLGFKVENYKDFKKDEICSN 287
           D  ++ LC IINN+ F+    +P R GTD D   L++ FT L ++V N  D  +++I + 
Sbjct: 40  DYPEMGLCIIINNKNFHESTGMPSRSGTDVDAANLRETFTNLKYEVRNKNDLTREQIVAL 99

Query: 288 LRELSERKELKNVSILVCIILSHGADGIIYGIDGPVELDRIFGYFKGDKCRQLAGKPKVF 467
           L  +S     K  S  +C++LSHG +GIIYG +GPV+L ++ G+F+GD CR L GKPK+F
Sbjct: 100 LDSVSREDHSKRSSF-ICVLLSHGEEGIIYGTNGPVDLKKLTGFFRGDYCRSLTGKPKLF 158

Query: 468 LFQACRGEKFDKGVQADGLFQTSV--EKIPVEADFLIGYSTVAGYFSWRNGRNGSWYIQA 641
           + QACRG + D G++ D   +  +  +KIPVEADFL  YST  GY+SWRN ++GSW+IQ+
Sbjct: 159 IIQACRGTELDCGIETDSGTEDDIACQKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQS 218

Query: 642 LCRELERSAQSMELIQXXXXXXXXXXXXXXSMTKNDKTDAMVQIPSFVCMLRKPLW 809
           LC  L   A  +E +               S + +       QIP  V ML K L+
Sbjct: 219 LCSMLRLYAHELEFMHILTRVNRKVATEFESFSLDSAFHGKKQIPCIVSMLTKELY 274
>sp|P42574|CASP3_HUMAN Caspase-3 precursor (CASP-3) (Apopain) (Cysteine protease CPP32)
           (Yama protein) (CPP-32) (SREBP cleavage activity 1)
           (SCA-1) [Contains: Caspase-3 p17 subunit; Caspase-3 p12
           subunit]
          Length = 277

 Score =  194 bits (493), Expect = 3e-49
 Identities = 97/236 (41%), Positives = 140/236 (59%), Gaps = 2/236 (0%)
 Frame = +3

Query: 108 DVSKIKLCYIINNEEFYTKLNLPKRLGTDEDFKRLKQVFTKLGFKVENYKDFKKDEICSN 287
           D  ++ LC IINN+ F+    +  R GTD D   L++ F  L ++V N  D  ++EI   
Sbjct: 40  DYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVEL 99

Query: 288 LRELSERKELKNVSILVCIILSHGADGIIYGIDGPVELDRIFGYFKGDKCRQLAGKPKVF 467
           +R++S+    K  S  VC++LSHG +GII+G +GPV+L +I  +F+GD+CR L GKPK+F
Sbjct: 100 MRDVSKEDHSKRSSF-VCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLF 158

Query: 468 LFQACRGEKFDKGVQADGLFQTSV--EKIPVEADFLIGYSTVAGYFSWRNGRNGSWYIQA 641
           + QACRG + D G++ D      +   KIPVEADFL  YST  GY+SWRN ++GSW+IQ+
Sbjct: 159 IIQACRGTELDCGIETDSGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQS 218

Query: 642 LCRELERSAQSMELIQXXXXXXXXXXXXXXSMTKNDKTDAMVQIPSFVCMLRKPLW 809
           LC  L++ A  +E +               S + +    A  QIP  V ML K L+
Sbjct: 219 LCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELY 274
>sp|Q5IS54|CASP3_PANTR Caspase-3 precursor (CASP-3) [Contains: Caspase-3 p17 subunit;
           Caspase-3 p12 subunit]
          Length = 277

 Score =  194 bits (493), Expect = 3e-49
 Identities = 97/236 (41%), Positives = 140/236 (59%), Gaps = 2/236 (0%)
 Frame = +3

Query: 108 DVSKIKLCYIINNEEFYTKLNLPKRLGTDEDFKRLKQVFTKLGFKVENYKDFKKDEICSN 287
           D  ++ LC IINN+ F+    +  R GTD D   L++ F  L ++V N  D  ++EI   
Sbjct: 40  DYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVEL 99

Query: 288 LRELSERKELKNVSILVCIILSHGADGIIYGIDGPVELDRIFGYFKGDKCRQLAGKPKVF 467
           +R++S+    K  S  VC++LSHG +GII+G +GPV+L +I  +F+GD+CR L GKPK+F
Sbjct: 100 MRDVSKEDHSKRSSF-VCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLF 158

Query: 468 LFQACRGEKFDKGVQADGLFQTSV--EKIPVEADFLIGYSTVAGYFSWRNGRNGSWYIQA 641
           + QACRG + D G++ D      +   KIPVEADFL  YST  GY+SWRN ++GSW+IQ+
Sbjct: 159 IIQACRGTELDCGIETDSGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQS 218

Query: 642 LCRELERSAQSMELIQXXXXXXXXXXXXXXSMTKNDKTDAMVQIPSFVCMLRKPLW 809
           LC  L++ A  +E +               S + +    A  QIP  V ML K L+
Sbjct: 219 LCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELY 274
>sp|Q8MKI5|CASP3_CANFA Caspase-3 precursor (CASP-3) [Contains: Caspase-3 p17 subunit;
           Caspase-3 p12 subunit]
          Length = 277

 Score =  193 bits (490), Expect = 6e-49
 Identities = 97/237 (40%), Positives = 139/237 (58%), Gaps = 2/237 (0%)
 Frame = +3

Query: 108 DVSKIKLCYIINNEEFYTKLNLPKRLGTDEDFKRLKQVFTKLGFKVENYKDFKKDEICSN 287
           D  ++ LC IINN+ F+    +  R GTD D   L++ FT L ++V N  D   +EI   
Sbjct: 40  DYPEMGLCIIINNKNFHKSTGMAPRSGTDVDAANLRETFTNLKYEVRNKNDLTCEEILEL 99

Query: 288 LRELSERKELKNVSILVCIILSHGADGIIYGIDGPVELDRIFGYFKGDKCRQLAGKPKVF 467
           +  +S+    K  S  VC++LSHG +GII+G +GPV+L ++ G+F+GD CR L GKPK+F
Sbjct: 100 MNSVSKEDHSKRSSF-VCVLLSHGDEGIIFGTNGPVDLRKVTGFFRGDYCRSLTGKPKLF 158

Query: 468 LFQACRGEKFDKGVQADGLFQTSV--EKIPVEADFLIGYSTVAGYFSWRNGRNGSWYIQA 641
           + QACRG + D G++ D   +  +  +KIPVEADFL  YST  GY+SWRN ++GSW+IQ+
Sbjct: 159 IIQACRGTELDCGIETDSGIEDDMACQKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQS 218

Query: 642 LCRELERSAQSMELIQXXXXXXXXXXXXXXSMTKNDKTDAMVQIPSFVCMLRKPLWL 812
           LC  L+  A  +E +               S + +       QIP  V ML K L+L
Sbjct: 219 LCAMLKLYAHKLEFMHILTRVNRKVATEFESFSLDSAFHGKKQIPCIVSMLTKELYL 275
>sp|Q60431|CASP3_CRILO Caspase-3 precursor (CASP-3) (Apopain) (Cysteine protease CPP32)
           (Yama protein) (CPP-32) (SREBP cleavage activity 1)
           (SCA-1) [Contains: Caspase-3 p17 subunit; Caspase-3 p12
           subunit]
          Length = 277

 Score =  191 bits (485), Expect = 2e-48
 Identities = 95/236 (40%), Positives = 139/236 (58%), Gaps = 2/236 (0%)
 Frame = +3

Query: 108 DVSKIKLCYIINNEEFYTKLNLPKRLGTDEDFKRLKQVFTKLGFKVENYKDFKKDEICSN 287
           D  ++ +C IINN+ F+    +  R GTD D  +L++ F  L ++V N  D  ++EI   
Sbjct: 40  DYPEMGVCIIINNKNFHKSTGMTPRSGTDVDAAKLRETFMALKYEVRNKNDLTREEIVEL 99

Query: 288 LRELSERKELKNVSILVCIILSHGADGIIYGIDGPVELDRIFGYFKGDKCRQLAGKPKVF 467
           ++  S+    K  S  VC+ILSHG +G+I+G DGP++L ++  YF+GD CR L GKPK+F
Sbjct: 100 MKNASKEDHSKRSSF-VCVILSHGDEGVIFGTDGPIDLKKLTSYFRGDYCRSLIGKPKLF 158

Query: 468 LFQACRGEKFDKGVQADGLFQTSV--EKIPVEADFLIGYSTVAGYFSWRNGRNGSWYIQA 641
           + QACRG + D G++ D   +  +  +KIPVEADFL  YST  GY+SWRN ++GSW+IQ+
Sbjct: 159 IIQACRGTELDCGIETDSGTEDDMTCQKIPVEADFLYAYSTAPGYYSWRNPKDGSWFIQS 218

Query: 642 LCRELERSAQSMELIQXXXXXXXXXXXXXXSMTKNDKTDAMVQIPSFVCMLRKPLW 809
           LC  L+  A  +E +               S + +    A  QIP  V ML K L+
Sbjct: 219 LCSMLKLYAHKLEFMHILTRVNRKVATEFESFSLDSTFHAKKQIPCIVSMLTKELY 274
>sp|P70677|CASP3_MOUSE Caspase-3 precursor (CASP-3) (Apopain) (Cysteine protease CPP32)
           (Yama protein) (CPP-32) (SREBP cleavage activity 1)
           (SCA-1) (LICE) [Contains: Caspase-3 p17 subunit;
           Caspase-3 p12 subunit]
          Length = 277

 Score =  189 bits (480), Expect = 9e-48
 Identities = 95/236 (40%), Positives = 138/236 (58%), Gaps = 2/236 (0%)
 Frame = +3

Query: 108 DVSKIKLCYIINNEEFYTKLNLPKRLGTDEDFKRLKQVFTKLGFKVENYKDFKKDEICSN 287
           D  ++ +C IINN+ F+    +  R GTD D   L++ F  L ++V N  D  +++I   
Sbjct: 40  DYPEMGICIIINNKNFHKSTGMSSRSGTDVDAANLRETFMGLKYQVRNKNDLTREDILEL 99

Query: 288 LRELSERKELKNVSILVCIILSHGADGIIYGIDGPVELDRIFGYFKGDKCRQLAGKPKVF 467
           +  +S+    K  S  VC+ILSHG +G+IYG +GPVEL ++  +F+GD CR L GKPK+F
Sbjct: 100 MDSVSKEDHSKRSSF-VCVILSHGDEGVIYGTNGPVELKKLTSFFRGDYCRSLTGKPKLF 158

Query: 468 LFQACRGEKFDKGVQADGLF--QTSVEKIPVEADFLIGYSTVAGYFSWRNGRNGSWYIQA 641
           + QACRG + D G++ D     + + +KIPVEADFL  YST  GY+SWRN ++GSW+IQ+
Sbjct: 159 IIQACRGTELDCGIETDSGTDEEMACQKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQS 218

Query: 642 LCRELERSAQSMELIQXXXXXXXXXXXXXXSMTKNDKTDAMVQIPSFVCMLRKPLW 809
           LC  L+  A  +E +               S + +    A  QIP  V ML K L+
Sbjct: 219 LCSMLKLYAHKLEFMHILTRVNRKVATEFESFSLDSTFHAKKQIPCIVSMLTKELY 274
>sp|Q8MJC3|CASP3_RABIT Caspase-3 precursor (CASP-3) (Apopain) (Cysteine protease CPP32)
           [Contains: Caspase-3 p17 subunit; Caspase-3 p12 subunit]
          Length = 277

 Score =  188 bits (478), Expect = 2e-47
 Identities = 94/236 (39%), Positives = 135/236 (57%), Gaps = 2/236 (0%)
 Frame = +3

Query: 108 DVSKIKLCYIINNEEFYTKLNLPKRLGTDEDFKRLKQVFTKLGFKVENYKDFKKDEICSN 287
           D  ++ LC IINN+ F+    +  R GTD +   L + F  L ++V N  D  ++EI   
Sbjct: 40  DYPEMGLCIIINNKNFHKNTGMSSRSGTDVNAANLGETFMNLKYEVRNKNDLTREEIMEL 99

Query: 288 LRELSERKELKNVSILVCIILSHGADGIIYGIDGPVELDRIFGYFKGDKCRQLAGKPKVF 467
           +  +S+    K  S  +C+ILSHG +G+IYG +GP+EL ++  +F+GD CR L GKPK+F
Sbjct: 100 MYNVSKEDHSKRSSF-ICVILSHGDEGVIYGTNGPIELKKLTSFFRGDYCRSLTGKPKLF 158

Query: 468 LFQACRGEKFDKGVQADG--LFQTSVEKIPVEADFLIGYSTVAGYFSWRNGRNGSWYIQA 641
           + QACRG + D G++ D    +  + +KIPVEADFL  YST  GY+SWRN   GSW+IQ+
Sbjct: 159 IIQACRGTELDSGIETDSGVDYDMACQKIPVEADFLYAYSTAPGYYSWRNSEEGSWFIQS 218

Query: 642 LCRELERSAQSMELIQXXXXXXXXXXXXXXSMTKNDKTDAMVQIPSFVCMLRKPLW 809
           LC  L+  A  +E +               S + +    A  QIP  V ML K L+
Sbjct: 219 LCAMLKEYAHKLEFMHILTRVNRKVATEFESYSLDATFHAKKQIPCIVSMLTKELY 274
>sp|P55213|CASP3_RAT Caspase-3 precursor (CASP-3) (Apopain) (Cysteine protease CPP32)
           (Yama protein) (CPP-32) (SREBP cleavage activity 1)
           (SCA-1) (LICE) (IRP) [Contains: Caspase-3 p17 subunit;
           Caspase-3 p12 subunit]
          Length = 277

 Score =  188 bits (477), Expect = 2e-47
 Identities = 96/236 (40%), Positives = 137/236 (58%), Gaps = 2/236 (0%)
 Frame = +3

Query: 108 DVSKIKLCYIINNEEFYTKLNLPKRLGTDEDFKRLKQVFTKLGFKVENYKDFKKDEICSN 287
           D  ++ LC IINN+ F+    +  R GTD D   L++ F  L ++V N  D  ++EI   
Sbjct: 40  DYPEMGLCIIINNKNFHKSTGMSARNGTDVDAANLRETFMALKYEVRNKNDLTREEIMEL 99

Query: 288 LRELSERKELKNVSILVCIILSHGADGIIYGIDGPVELDRIFGYFKGDKCRQLAGKPKVF 467
           +  +S+    K  S  VC+ILSHG +G+I+G +GPV+L ++  +F+GD CR L GKPK+F
Sbjct: 100 MDSVSKEDHSKRSSF-VCVILSHGDEGVIFGTNGPVDLKKLTSFFRGDYCRSLTGKPKLF 158

Query: 468 LFQACRGEKFDKGVQADGLFQTSV--EKIPVEADFLIGYSTVAGYFSWRNGRNGSWYIQA 641
           + QACRG + D G++ D      +  +KIPVEADFL  YST  GY+SWRN R+GSW+IQ+
Sbjct: 159 IIQACRGTELDCGIETDSGTDDDMACQKIPVEADFLYAYSTAPGYYSWRNSRDGSWFIQS 218

Query: 642 LCRELERSAQSMELIQXXXXXXXXXXXXXXSMTKNDKTDAMVQIPSFVCMLRKPLW 809
           LC  L+  A  +E +               S + +    A  QIP  V ML K L+
Sbjct: 219 LCAMLKLYAHKLEFMHILTRVNRKVATEFESFSLDATFHAKKQIPCIVSMLTKELY 274
>sp|Q95ND5|CASP3_PIG Caspase-3 precursor (CASP-3) [Contains: Caspase-3 p17 subunit;
           Caspase-3 p12 subunit]
          Length = 277

 Score =  187 bits (476), Expect = 3e-47
 Identities = 94/236 (39%), Positives = 138/236 (58%), Gaps = 2/236 (0%)
 Frame = +3

Query: 108 DVSKIKLCYIINNEEFYTKLNLPKRLGTDEDFKRLKQVFTKLGFKVENYKDFKKDEICSN 287
           D  ++ LC IINN+ F     +  R GTD D   L++ FT L ++V N  D  ++EI   
Sbjct: 40  DYPEMGLCIIINNKNFDKNTGMACRSGTDVDAANLRETFTNLKYEVRNKNDLTREEILEL 99

Query: 288 LRELSERKELKNVSILVCIILSHGADGIIYGIDGPVELDRIFGYFKGDKCRQLAGKPKVF 467
           +  +S+    K  S  +C++LSHG +G I+G +GPV+L ++  +F+GD CR L GKPK+F
Sbjct: 100 MHSVSKEDHSKRSSF-ICVLLSHGEEGKIFGTNGPVDLKKLTSFFRGDCCRTLTGKPKLF 158

Query: 468 LFQACRGEKFDKGVQADGLFQTSV--EKIPVEADFLIGYSTVAGYFSWRNGRNGSWYIQA 641
           + QACRG + D G++ D   +  +  +KIPVEADFL  YST  GY+SWRN ++GSW+IQ+
Sbjct: 159 IIQACRGTELDCGIETDSGTEDDMACQKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQS 218

Query: 642 LCRELERSAQSMELIQXXXXXXXXXXXXXXSMTKNDKTDAMVQIPSFVCMLRKPLW 809
           LC  L++    +EL+               S + +    A  QIP  V ML K L+
Sbjct: 219 LCAALKQYVHKLELMHILTRVNRKVAVEFESFSTDSTFHAKKQIPCIVSMLTKELY 274
>sp|P55214|CASP7_MESAU Caspase-7 precursor (CASP-7) (ICE-like apoptotic protease 3)
           (ICE-LAP3) (Apoptotic protease Mch-3) (SREBP cleavage
           activity 2) (SCA-2) [Contains: Caspase-7 subunit p20;
           Caspase-7 subunit p11]
          Length = 303

 Score =  171 bits (432), Expect = 3e-42
 Identities = 95/239 (39%), Positives = 132/239 (55%), Gaps = 5/239 (2%)
 Frame = +3

Query: 108 DVSKIKLCYIINNEEFYTKLNLPKRLGTDEDFKRLKQVFTKLGFKVENYKDFKKDEICSN 287
           D  K+  C IINN+ F     +  R GTD+D + L + F  LGF V  Y D    ++   
Sbjct: 63  DFEKMGKCIIINNKNFDKVTGMDVRNGTDKDAEALFKCFRSLGFDVVVYNDCSCAKMQDL 122

Query: 288 LRELSERKELKNVSILVCIILSHGADGIIYGIDGPVELDRIFGYFKGDKCRQLAGKPKVF 467
           LR+ SE ++  N +   C++LSHG + +IYG DG   +  +  +F+GD+C+ L  KPK+F
Sbjct: 123 LRKASE-EDHSNSACFACVLLSHGEENLIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLF 181

Query: 468 LFQACRGEKFDKGVQADG--LFQTSVE---KIPVEADFLIGYSTVAGYFSWRNGRNGSWY 632
             QACRG + D GVQAD   + +T      KIPVEADFL  YSTV GY+SWRN   GSW+
Sbjct: 182 FIQACRGTELDDGVQADSGPINETDANPRYKIPVEADFLFAYSTVPGYYSWRNPGKGSWF 241

Query: 633 IQALCRELERSAQSMELIQXXXXXXXXXXXXXXSMTKNDKTDAMVQIPSFVCMLRKPLW 809
           +QALC  L+   + +E++Q              S   +   +   QIP  V ML K L+
Sbjct: 242 VQALCSILDEHGKDLEIMQILTRVNDRVARHFESQCDDPCFNEKKQIPCMVSMLTKELY 300
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 96,039,804
Number of Sequences: 369166
Number of extensions: 1922358
Number of successful extensions: 4622
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4402
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4532
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9126484700
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)