Planaria EST Database


DrC_01881

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_01881
         (859 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|P37276|DYHC_DROME  Dynein heavy chain, cytosolic (DYHC)        257   3e-68
sp|Q9JHU4|DYHC_MOUSE  Dynein heavy chain, cytosolic (DYHC) (...   246   8e-65
sp|Q14204|DYHC_HUMAN  Dynein heavy chain, cytosolic (DYHC) (...   241   2e-63
sp|P38650|DYHC_RAT  Dynein heavy chain, cytosolic (DYHC) (Cy...   239   7e-63
sp|Q19020|DYHC_CAEEL  Dynein heavy chain, cytosolic (DYHC)        192   1e-48
sp|P34036|DYHC_DICDI  Dynein heavy chain, cytosolic (DYHC)        169   7e-42
sp|Q27171|DYHC_PARTE  Dynein heavy chain, cytosolic (DYHC) (...   152   9e-37
sp|Q9NYC9|DYH9_HUMAN  Ciliary dynein heavy chain 9 (Axonemal...    62   2e-09
sp|P23098|DYHC_TRIGR  Dynein beta chain, ciliary                   60   6e-09
sp|P39057|DYHC_ANTCR  Dynein beta chain, ciliary                   58   3e-08
>sp|P37276|DYHC_DROME Dynein heavy chain, cytosolic (DYHC)
          Length = 4639

 Score =  257 bits (656), Expect = 3e-68
 Identities = 132/261 (50%), Positives = 176/261 (67%), Gaps = 4/261 (1%)
 Frame = +1

Query: 52   DGRPAWMRQLYQSTQTWLQILPKSVTPLQRTSENIKDPMYRCFEREVNSGCNLLIAVRRD 231
            DGRP+WM+ L+ S   WL++LPK++  L+RT ENIKDP+YR FEREV SG  LL  V  D
Sbjct: 4361 DGRPSWMKTLHNSATAWLELLPKNLQVLKRTVENIKDPLYRYFEREVTSGSRLLQTVILD 4420

Query: 232  LEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKTWVRYAIPPGLTVIQWIQDFADRVKQLI 411
            L+DV  +C+G KK TNHHRSM+++L +GIIPK W RY +P G TVIQWI DF++RV+QL 
Sbjct: 4421 LQDVVLICQGEKKQTNHHRSMLSELVRGIIPKGWKRYTVPAGCTVIQWITDFSNRVQQLQ 4480

Query: 412  SISDTAAKSGVSALRDSKVWLGGLFMAEAYITATRQSVAQANKWALEELFLDVELGDG-- 585
             +S   +++G   L+   VWLGGL   EAYITATRQ VAQAN W+LEEL LDV + D   
Sbjct: 4481 KVSQLVSQAGAKELQGFPVWLGGLLNPEAYITATRQCVAQANSWSLEELALDVTITDAGL 4540

Query: 586  KVDGNTCV--VTGLRLMGSEIVDSRTLKLSTLIYKDIDICRLKWIRVEKSQQLLDASSVS 759
            K D   C   VTGL+L G++  ++  L  ST I  D+ +  LKWI++    ++       
Sbjct: 4541 KNDQKDCCFGVTGLKLQGAQCKNNELLLAST-IMMDLPVTILKWIKISSEPRI------- 4592

Query: 760  KDKVCLPIYLNAARSTVLFTL 822
              K+ LP+YLN+ R+ +LFT+
Sbjct: 4593 -SKLTLPVYLNSTRTELLFTV 4612
>sp|Q9JHU4|DYHC_MOUSE Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain)
          Length = 4644

 Score =  246 bits (627), Expect = 8e-65
 Identities = 124/271 (45%), Positives = 180/271 (66%), Gaps = 3/271 (1%)
 Frame = +1

Query: 25   KSKRTIEVGDGRPAWMRQLYQSTQTWLQILPKSVTPLQRTSENIKDPMYRCFEREVNSGC 204
            K  RT    DGRPAWMR L+ +   WL ++P++++PL+RT ENIKDP++R FEREV  G 
Sbjct: 4360 KKARTDSTSDGRPAWMRTLHTTASNWLHLIPQTLSPLKRTVENIKDPLFRFFEREVKMGA 4419

Query: 205  NLLIAVRRDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKTWVRYAIPPGLTVIQWIQD 384
             LL  VR+DL DV +VC+G KK TN+ R+++ +L KGI+P++W  Y +P G+TVIQW+ D
Sbjct: 4420 KLLQDVRQDLADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSD 4479

Query: 385  FADRVKQLISISDTAAKSGVSALRDSKVWLGGLFMAEAYITATRQSVAQANKWALEELFL 564
            F++R+KQL +IS  AA  G   L++  V LGGLF+ EAYITATRQ VAQAN W+LEEL L
Sbjct: 4480 FSERIKQLQNISQAAASGGAKELKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCL 4539

Query: 565  DVEL---GDGKVDGNTCVVTGLRLMGSEIVDSRTLKLSTLIYKDIDICRLKWIRVEKSQQ 735
            +V +       +D  +  VTGL+L G+   +++ L LS  I   + + +L+W++   +++
Sbjct: 4540 EVNVTASQSATLDACSFGVTGLKLQGATCSNNK-LSLSNAISTVLPLTQLRWVKQTSAEK 4598

Query: 736  LLDASSVSKDKVCLPIYLNAARSTVLFTLYF 828
                       V LP+YLN  R+ ++FT+ F
Sbjct: 4599 -------KASVVTLPVYLNFTRADLIFTVDF 4622
>sp|Q14204|DYHC_HUMAN Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain
            1) (DHC1)
          Length = 4646

 Score =  241 bits (615), Expect = 2e-63
 Identities = 123/271 (45%), Positives = 179/271 (66%), Gaps = 3/271 (1%)
 Frame = +1

Query: 25   KSKRTIEVGDGRPAWMRQLYQSTQTWLQILPKSVTPLQRTSENIKDPMYRCFEREVNSGC 204
            K  RT    DGRPAWMR L+ +   WL ++P++++ L+RT ENIKDP++R FEREV  G 
Sbjct: 4362 KKTRTDSTSDGRPAWMRTLHTTASNWLHLIPQTLSHLKRTVENIKDPLFRFFEREVKMGA 4421

Query: 205  NLLIAVRRDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKTWVRYAIPPGLTVIQWIQD 384
             LL  VR+DL DV +VC+G KK TN+ R+++ +L KGI+P++W  Y +P G+TVIQW+ D
Sbjct: 4422 KLLQDVRQDLADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSD 4481

Query: 385  FADRVKQLISISDTAAKSGVSALRDSKVWLGGLFMAEAYITATRQSVAQANKWALEELFL 564
            F++R+KQL +IS  AA  G   L++  V LGGLF+ EAYITATRQ VAQAN W+LEEL L
Sbjct: 4482 FSERIKQLQNISLAAASGGAKELKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCL 4541

Query: 565  DVELGDGK---VDGNTCVVTGLRLMGSEIVDSRTLKLSTLIYKDIDICRLKWIRVEKSQQ 735
            +V +   +   +D  +  VTGL+L G+   ++  L LS  I   + + +L+W++   +++
Sbjct: 4542 EVNVTTSQGATLDACSFGVTGLKLQGA-TCNNNKLSLSNAISTALPLTQLRWVKQTNTEK 4600

Query: 736  LLDASSVSKDKVCLPIYLNAARSTVLFTLYF 828
                       V LP+YLN  R+ ++FT+ F
Sbjct: 4601 -------KASVVTLPVYLNFTRADLIFTVDF 4624
>sp|P38650|DYHC_RAT Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain)
            (MAP 1C)
          Length = 4644

 Score =  239 bits (610), Expect = 7e-63
 Identities = 123/271 (45%), Positives = 179/271 (66%), Gaps = 3/271 (1%)
 Frame = +1

Query: 25   KSKRTIEVGDGRPAWMRQLYQSTQTWLQILPKSVTPLQRTSENIKDPMYRCFEREVNSGC 204
            K  RT    DGRPAWMR L+ +   WL ++P++++PL+RT ENIKDP++R FEREV  G 
Sbjct: 4360 KKTRTDFTSDGRPAWMRTLHTTASNWLHLIPQTLSPLKRTVENIKDPLFRFFEREVKMGA 4419

Query: 205  NLLIAVRRDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKTWVRYAIPPGLTVIQWIQD 384
             LL  VR+DL DV +VC+G KK TN+ R+++ +L KGI+P++W  Y +P G+TVIQW+ D
Sbjct: 4420 KLLQDVRQDLADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSD 4479

Query: 385  FADRVKQLISISDTAAKSGVSALRDSKVWLGGLFMAEAYITATRQSVAQANKWALEELFL 564
            F++R+KQL +IS  AA  G   L++  V LG LF+ EAYITATRQ VAQAN W+LEEL L
Sbjct: 4480 FSERIKQLQNISQAAAAGGAKELKNIHVCLGALFVPEAYITATRQYVAQANSWSLEELCL 4539

Query: 565  DVELGDGK---VDGNTCVVTGLRLMGSEIVDSRTLKLSTLIYKDIDICRLKWIRVEKSQQ 735
            +V +   +   +D  +  VTGL+L G+   +++ L LS  I   + + +L+W +   +++
Sbjct: 4540 EVNVTASQSTTLDACSFGVTGLKLQGATCSNNK-LSLSNAISTVLPLTQLRWGKQTSAEK 4598

Query: 736  LLDASSVSKDKVCLPIYLNAARSTVLFTLYF 828
                       V LP+YLN  R+ ++FT+ F
Sbjct: 4599 -------KASVVTLPVYLNFTRADLIFTVDF 4622
>sp|Q19020|DYHC_CAEEL Dynein heavy chain, cytosolic (DYHC)
          Length = 4568

 Score =  192 bits (488), Expect = 1e-48
 Identities = 104/259 (40%), Positives = 148/259 (57%), Gaps = 1/259 (0%)
 Frame = +1

Query: 58   RPAWMRQLYQSTQTWLQILPKSVTPLQRTSENIKDPMYRCFEREVNSGCNLLIAVRRDLE 237
            +P WM QL +  + WLQ+LPK +  ++RT ENIKDP++R FEREVN G  LL  +RRDL 
Sbjct: 4310 KPQWMAQLGELAKQWLQLLPKEIVKMRRTVENIKDPLFRFFEREVNLGSQLLKDIRRDLN 4369

Query: 238  DVAEVCKGAKKPTNHHRSMMADLAKGIIPKTWVRYAIPPGLTVIQWIQDFADRVKQLISI 417
            +++ VC+  KK  N  R++ A L KG +P  W RY +P  +TV+ W+ D  +R+KQLI I
Sbjct: 4370 EISAVCRAEKKQNNETRALAASLQKGEVPTGWKRYTVpreVTVMDWMTDLNERLKQLIRI 4429

Query: 418  SDTAAKSGVSALRDSKVWLGGLFMAEAYITATRQSVAQANKWALEELFLDVELGDGKVDG 597
                   G   L+    WLGG F  EAYITATRQ VAQAN W+LE+L L + +  G+ D 
Sbjct: 4430 ------GGADNLKRETFWLGGTFSPEAYITATRQQVAQANTWSLEQLNLHIHI--GRTDS 4481

Query: 598  NTCV-VTGLRLMGSEIVDSRTLKLSTLIYKDIDICRLKWIRVEKSQQLLDASSVSKDKVC 774
                 ++G+ + G++ V    L+L  L+  + DI    W      Q + D +        
Sbjct: 4482 TDVFRISGIDIRGAKSVGGNKLELCELVKSECDIVEFSW-----KQDVADGTR------- 4529

Query: 775  LPIYLNAARSTVLFTLYFN 831
            LP+YL   R  ++  L F+
Sbjct: 4530 LPLYLYGDRRQLISPLAFH 4548
>sp|P34036|DYHC_DICDI Dynein heavy chain, cytosolic (DYHC)
          Length = 4725

 Score =  169 bits (429), Expect = 7e-42
 Identities = 98/253 (38%), Positives = 152/253 (60%), Gaps = 2/253 (0%)
 Frame = +1

Query: 100  WLQILPKSVTPLQRTSENIKDPMYRCFEREVNSGCNLLIAVRRDLEDVAEVCKGAKKPTN 279
            W ++LPK +  L+RT++NIKDP++RCFERE+++G  L+  +  DL ++ E+  G  K TN
Sbjct: 4468 WTKLLPKPLKQLKRTTQNIKDPLFRCFEREISTGGKLVKKITNDLANLLELISGNIKSTN 4527

Query: 280  HHRSMMADLAKGIIPKTWVRYAIPPGLTVIQWIQDFADRVKQLISISDTAAKSGVSALRD 459
            + RS+   ++KGI+PK W  Y++P  +++  WI DF+ R++QL  IS+++  S +     
Sbjct: 4528 YLRSLTTSISKGIVPKEWKWYSVPETISLSVWISDFSKRMQQLSEISESSDYSSI----- 4582

Query: 460  SKVWLGGLFMAEAYITATRQSVAQANKWALEELFLDV-ELGDGKVDGNTCV-VTGLRLMG 633
             +VWLGGL   EAYITATRQS +Q N W+LE L L    LG    +G     V G+ L G
Sbjct: 4583 -QVWLGGLLNPEAYITATRQSASQLNGWSLENLRLHASSLGKISSEGGASFNVKGMALEG 4641

Query: 634  SEIVDSRTLKLSTLIYKDIDICRLKWIRVEKSQQLLDASSVSKDKVCLPIYLNAARSTVL 813
            + + ++  L  + ++   I I  L W   +K   + + SS    K+ +P+YLN  RS +L
Sbjct: 4642 A-VWNNDQLTPTDILSTPISIATLTW--KDKDDPIFNNSS---SKLSVPVYLNETRSELL 4695

Query: 814  FTLYFNTTDLSYD 852
            F++     DL YD
Sbjct: 4696 FSI-----DLPYD 4703
>sp|Q27171|DYHC_PARTE Dynein heavy chain, cytosolic (DYHC) (DHC08)
          Length = 4540

 Score =  152 bits (385), Expect = 9e-37
 Identities = 85/256 (33%), Positives = 143/256 (55%), Gaps = 4/256 (1%)
 Frame = +1

Query: 67   WMRQLYQSTQTWLQILPKSVTPLQRTSENIKDPMYRCFEREVNSGCNLLIAVRRDLEDVA 246
            W++ L +  + +  ILP  ++PL+RT+++I DP++R  +RE+     LL AVR+++E++ 
Sbjct: 4278 WLQDLLEKVEKFKAILPNKISPLERTADSINDPLFRFLDREITVASKLLKAVRQNIEELI 4337

Query: 247  EVCKGAKKPTNHHRSMMADLAKGIIPKTWVRYAIPPGLTVIQWIQDFADRVKQLISISDT 426
            ++ +G    TN  R +  D+   I+P  W +Y +   + +  W+ DF  R+ Q   +  T
Sbjct: 4338 QLAQGKILATNILRQLAKDVFNNIVPAQWNKYNVIT-MPLNDWVGDFKRRIDQFDLLGKT 4396

Query: 427  AAKSGVSALRDSKVWLGGLFMAEAYITATRQSVAQANKWALEELFLDVELGDGKVDGNTC 606
                     +  +VW GGL   EAY+TATRQ VAQANKW+LEEL L +   D  +D ++ 
Sbjct: 4397 ------KDFQKGQVWFGGLLFPEAYLTATRQYVAQANKWSLEELELQMIPEDQGIDEDSF 4450

Query: 607  VVTGLRLMGSEIVDSRTLKLSTLIYKDIDIC----RLKWIRVEKSQQLLDASSVSKDKVC 774
            V+ G+ + G  + DS+TL++   I  +I +      LKW +  +         V  D++ 
Sbjct: 4451 VIEGVSMEGGHL-DSKTLQVR--IVNEISVALKPITLKWCKTSQK------GVVGDDEIV 4501

Query: 775  LPIYLNAARSTVLFTL 822
            LP+YLN  R  ++F+L
Sbjct: 4502 LPVYLNKTRKNLIFSL 4517
>sp|Q9NYC9|DYH9_HUMAN Ciliary dynein heavy chain 9 (Axonemal beta dynein heavy chain 9)
          Length = 4486

 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 34/119 (28%), Positives = 62/119 (52%)
 Frame = +1

Query: 220  VRRDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKTWVRYAIPPGLTVIQWIQDFADRV 399
            ++R L ++    KG    T+H  ++   L   ++P++W R A P    +  W  D  +R+
Sbjct: 4269 IQRSLRELELGLKGELTMTSHMENLQNALYFDMVPESWARRAYPSTAGLAAWFPDLLNRI 4328

Query: 400  KQLISISDTAAKSGVSALRDSKVWLGGLFMAEAYITATRQSVAQANKWALEELFLDVEL 576
            K+L       A +G   +  S VWL G F  ++++TA  QS A+ N+W L+++ L  ++
Sbjct: 4329 KEL------EAWTGDFTM-PSTVWLTGFFNPQSFLTAIMQSTARKNEWPLDQIALQCDM 4380
>sp|P23098|DYHC_TRIGR Dynein beta chain, ciliary
          Length = 4466

 Score = 60.5 bits (145), Expect = 6e-09
 Identities = 36/119 (30%), Positives = 58/119 (48%)
 Frame = +1

Query: 220  VRRDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKTWVRYAIPPGLTVIQWIQDFADRV 399
            +RR L+++    KG    T     +   L    IP TWV+ A P    +  W  D   R+
Sbjct: 4249 IRRSLKELDLGLKGELTITPDMEDLSNALFLDQIPATWVKRAYPSLFGLTSWYADLLQRI 4308

Query: 400  KQLISISDTAAKSGVSALRDSKVWLGGLFMAEAYITATRQSVAQANKWALEELFLDVEL 576
            K+L   +   A   V       VWLGG F  ++++TA  QS+A+ N+W L+++ L  ++
Sbjct: 4309 KELEQWTADFALPNV-------VWLGGFFNPQSFLTAIMQSMARKNEWPLDKMCLQCDV 4360
>sp|P39057|DYHC_ANTCR Dynein beta chain, ciliary
          Length = 4466

 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 35/119 (29%), Positives = 58/119 (48%)
 Frame = +1

Query: 220  VRRDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKTWVRYAIPPGLTVIQWIQDFADRV 399
            +RR L+++    KG    T     +   L    IP +WV+ A P    +  W  D   R+
Sbjct: 4249 IRRSLKELDLGLKGELTITPDMEDLSNALFLDQIPASWVKRAYPSLFGLSAWYADLLQRI 4308

Query: 400  KQLISISDTAAKSGVSALRDSKVWLGGLFMAEAYITATRQSVAQANKWALEELFLDVEL 576
            K+L   +   A   V       VWLGG F  ++++TA  QS+A+ N+W L+++ L  ++
Sbjct: 4309 KELEQWTADFALPNV-------VWLGGFFNPQSFLTAIMQSMARKNEWPLDKMCLQCDV 4360
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 97,565,848
Number of Sequences: 369166
Number of extensions: 1934199
Number of successful extensions: 4721
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4557
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4706
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8486520240
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)