Planaria EST Database


DrC_01860

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_01860
         (869 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q96NX5|KCC1G_HUMAN  Calcium/calmodulin-dependent protein ...   122   2e-27
sp|Q91VB2|KCC1G_MOUSE  Calcium/calmodulin-dependent protein ...   119   1e-26
sp|Q7TNJ7|KCC1G_RAT  Calcium/calmodulin-dependent protein ki...   119   1e-26
sp|O70405|ULK1_MOUSE  Serine/threonine-protein kinase ULK1 (...   109   9e-24
sp|Q8IU85|KCC1D_HUMAN  Calcium/calmodulin-dependent protein ...   108   2e-23
sp|Q8BW96|KCC1D_MOUSE  Calcium/calmodulin-dependent protein ...   108   2e-23
sp|Q15139|KPCD1_HUMAN  Protein kinase, D1 type (nPKC-D1) (Pr...   107   3e-23
sp|O94806|KPCN_HUMAN  Protein kinase C, nu type (nPKC-nu) (P...   107   3e-23
sp|Q8ICR0|CDPK2_PLAF7  Calcium-dependent protein kinase 2 (P...   107   3e-23
sp|O15865|CDPK2_PLAFK  Calcium-dependent protein kinase 2 (P...   107   3e-23
>sp|Q96NX5|KCC1G_HUMAN Calcium/calmodulin-dependent protein kinase type 1G (CaM kinase IG)
           (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI
           gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III)
          Length = 476

 Score =  122 bits (305), Expect = 2e-27
 Identities = 79/233 (33%), Positives = 116/233 (49%), Gaps = 27/233 (11%)
 Frame = +1

Query: 7   TGKTVAIKVIKNFGF--DSDNERELDNLKKLSGENIVQLIDFIIKYNTAYLIMELCKGD- 177
           TGK  A+K IK      DS  E E+  LKK+  ENIV L D        YL+M+L  G  
Sbjct: 45  TGKLFALKCIKKSPAFRDSSLENEIAVLKKIKHENIVTLEDIYESTTHYYLVMQLVSGGE 104

Query: 178 ----VSETGKLTGPKLKDFIQQTTTGLKIIHDKGMIHRDIKPQNILHVTKGKRTIYKLTD 345
               + E G  T       IQQ  + +K +H+ G++HRD+KP+N+L++T  + +   +TD
Sbjct: 105 LFDRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITD 164

Query: 346 FGLSKMISRTHRMTKCGTPVFMAPEVAEGTEANSSADIWSLGITFCYMISG--------- 498
           FGLSKM       T CGTP ++APEV      + + D WS+G+    ++ G         
Sbjct: 165 FGLSKMEQNGIMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVITYILLCGYPPFYEETE 224

Query: 499 -----DIKDLGYE------DKTKGDLKDLISKMVKEKFRERITVDQILSHPYL 624
                 IK+  YE      D      KD I  ++++   ER T ++ LSHP++
Sbjct: 225 SKLFEKIKEGYYEFESPFWDDISESAKDFICHLLEKDPNERYTCEKALSHPWI 277
>sp|Q91VB2|KCC1G_MOUSE Calcium/calmodulin-dependent protein kinase type 1G (CaM kinase IG)
           (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI
           gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III)
          Length = 477

 Score =  119 bits (297), Expect = 1e-26
 Identities = 77/233 (33%), Positives = 115/233 (49%), Gaps = 27/233 (11%)
 Frame = +1

Query: 7   TGKTVAIKVIKNFGF--DSDNERELDNLKKLSGENIVQLIDFIIKYNTAYLIMELCKGD- 177
           TGK  A+K IK      DS  E E+  LK++  ENIV L D        YL+M+L  G  
Sbjct: 45  TGKLFALKCIKKSPAFRDSSLENEIAVLKRIKHENIVTLEDIYESTTHYYLVMQLVSGGE 104

Query: 178 ----VSETGKLTGPKLKDFIQQTTTGLKIIHDKGMIHRDIKPQNILHVTKGKRTIYKLTD 345
               + E G  T       IQQ  + +K +H+ G++HRD+KP+N+L++T  + +   +TD
Sbjct: 105 LFDRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITD 164

Query: 346 FGLSKMISRTHRMTKCGTPVFMAPEVAEGTEANSSADIWSLGITFCYMISG--------- 498
           FGLSKM       T CGTP ++APEV      + + D WS+G+    ++ G         
Sbjct: 165 FGLSKMEQNGVMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVITYILLCGYPPFYEETE 224

Query: 499 -----DIKDLGYE------DKTKGDLKDLISKMVKEKFRERITVDQILSHPYL 624
                 IK+  YE      D      KD I  ++++   ER T ++ L HP++
Sbjct: 225 SKLFEKIKEGYYEFESPFWDDISESAKDFICHLLEKDPNERYTCEKALRHPWI 277
>sp|Q7TNJ7|KCC1G_RAT Calcium/calmodulin-dependent protein kinase type 1G (CaM kinase IG)
           (CaM kinase I gamma) (CaMKI gamma) (CaMKI-gamma) (CaM-KI
           gamma) (CaMKIG) (CaMK-like CREB kinase III) (CLICK III)
          Length = 476

 Score =  119 bits (297), Expect = 1e-26
 Identities = 77/233 (33%), Positives = 115/233 (49%), Gaps = 27/233 (11%)
 Frame = +1

Query: 7   TGKTVAIKVIKNFGF--DSDNERELDNLKKLSGENIVQLIDFIIKYNTAYLIMELCKGD- 177
           TGK  A+K IK      DS  E E+  LK++  ENIV L D        YL+M+L  G  
Sbjct: 45  TGKLFALKCIKKSPAFRDSSLENEIAVLKRIKHENIVTLEDIYESTTHYYLVMQLVSGGE 104

Query: 178 ----VSETGKLTGPKLKDFIQQTTTGLKIIHDKGMIHRDIKPQNILHVTKGKRTIYKLTD 345
               + E G  T       IQQ  + +K +H+ G++HRD+KP+N+L++T  + +   +TD
Sbjct: 105 LFDRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITD 164

Query: 346 FGLSKMISRTHRMTKCGTPVFMAPEVAEGTEANSSADIWSLGITFCYMISG--------- 498
           FGLSKM       T CGTP ++APEV      + + D WS+G+    ++ G         
Sbjct: 165 FGLSKMEQNGVMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVITYILLCGYPPFYEETE 224

Query: 499 -----DIKDLGYE------DKTKGDLKDLISKMVKEKFRERITVDQILSHPYL 624
                 IK+  YE      D      KD I  ++++   ER T ++ L HP++
Sbjct: 225 SKLFEKIKEGYYEFESPFWDDISESAKDFICHLLEKDPNERYTCEKALRHPWI 277
>sp|O70405|ULK1_MOUSE Serine/threonine-protein kinase ULK1 (Unc-51-like kinase 1)
           (Serine/threonine-protein kinase Unc51.1)
          Length = 1051

 Score =  109 bits (273), Expect = 9e-24
 Identities = 71/218 (32%), Positives = 112/218 (51%), Gaps = 32/218 (14%)
 Frame = +1

Query: 67  RELDNLKKLSGENIVQLIDFIIKYNTAYLIMELCKG----DVSETGK-LTGPKLKDFIQQ 231
           +E+  LK+L  ENIV L DF    N+ YL+ME C G    D   T + L+   ++ F+QQ
Sbjct: 62  KEIKILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHTMRTLSEDTVRLFLQQ 121

Query: 232 TTTGLKIIHDKGMIHRDIKPQNILHVTKGKRTI------YKLTDFGLSKMI-SRTHRMTK 390
               ++++H KG+IHRD+KPQNIL    G R         K+ DFG ++ + S     T 
Sbjct: 122 IAGAMRLLHSKGIIHRDLKPQNILLSNPGGRRANPSNIRVKIADFGFARYLQSNMMAATL 181

Query: 391 CGTPVFMAPEVAEGTEANSSADIWSLGITFCYMISG----------DIKDLGYED----- 525
           CG+P++MAPEV      +  AD+WS+G      ++G          D++ L YE      
Sbjct: 182 CGSPMYMAPEVIMSQHYDGKADLWSIGTIVYQCLTGKAPFQASSPQDLR-LFYEKNKTLV 240

Query: 526 -----KTKGDLKDLISKMVKEKFRERITVDQILSHPYL 624
                +T   L+ L+  +++   ++R+  D+   HP+L
Sbjct: 241 PAIpreTSAPLRQLLLALLQRNHKDRMDFDEFFHHPFL 278
>sp|Q8IU85|KCC1D_HUMAN Calcium/calmodulin-dependent protein kinase type 1D (CaM kinase ID)
           (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI
           delta) (Camk1D) (CamKI-like protein kinase) (CKLiK)
          Length = 385

 Score =  108 bits (270), Expect = 2e-23
 Identities = 73/235 (31%), Positives = 113/235 (48%), Gaps = 29/235 (12%)
 Frame = +1

Query: 7   TGKTVAIKVIKNF---GFDSDNERELDNLKKLSGENIVQLIDFIIKYNTAYLIMELCKGD 177
           TGK  A+K I      G +S  E E+  L+K+  ENIV L D     N  YL+M+L  G 
Sbjct: 45  TGKLFAVKCIPKKALKGKESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGG 104

Query: 178 -----VSETGKLTGPKLKDFIQQTTTGLKIIHDKGMIHRDIKPQNILHVTKGKRTIYKLT 342
                + E G  T       I+Q    +  +H  G++HRD+KP+N+L+ ++ + +   ++
Sbjct: 105 ELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMIS 164

Query: 343 DFGLSKMISRTHRM-TKCGTPVFMAPEVAEGTEANSSADIWSLGITFCYMISG------- 498
           DFGLSKM  +   M T CGTP ++APEV      + + D WS+G+    ++ G       
Sbjct: 165 DFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDE 224

Query: 499 -DIK------------DLGYEDKTKGDLKDLISKMVKEKFRERITVDQILSHPYL 624
            D K            D  Y D      KD I  ++++   +R T +Q   HP++
Sbjct: 225 NDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWI 279
>sp|Q8BW96|KCC1D_MOUSE Calcium/calmodulin-dependent protein kinase type 1D (CaM kinase ID)
           (CaM kinase I delta) (CaMKI-delta) (CaM-KI delta) (CaMKI
           delta) (Camk1D) (CamKI-like protein kinase) (CKLiK)
           (mCKLiK)
          Length = 385

 Score =  108 bits (270), Expect = 2e-23
 Identities = 73/235 (31%), Positives = 113/235 (48%), Gaps = 29/235 (12%)
 Frame = +1

Query: 7   TGKTVAIKVIKNF---GFDSDNERELDNLKKLSGENIVQLIDFIIKYNTAYLIMELCKGD 177
           TGK  A+K I      G +S  E E+  L+K+  ENIV L D     N  YL+M+L  G 
Sbjct: 45  TGKLFAVKCIPKKALKGKESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGG 104

Query: 178 -----VSETGKLTGPKLKDFIQQTTTGLKIIHDKGMIHRDIKPQNILHVTKGKRTIYKLT 342
                + E G  T       I+Q    +  +H  G++HRD+KP+N+L+ ++ + +   ++
Sbjct: 105 ELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMIS 164

Query: 343 DFGLSKMISRTHRM-TKCGTPVFMAPEVAEGTEANSSADIWSLGITFCYMISG------- 498
           DFGLSKM  +   M T CGTP ++APEV      + + D WS+G+    ++ G       
Sbjct: 165 DFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDE 224

Query: 499 -DIK------------DLGYEDKTKGDLKDLISKMVKEKFRERITVDQILSHPYL 624
            D K            D  Y D      KD I  ++++   +R T +Q   HP++
Sbjct: 225 NDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWI 279
>sp|Q15139|KPCD1_HUMAN Protein kinase, D1 type (nPKC-D1) (Protein kinase D) (Protein kinase
            C, mu type) (nPKC-mu)
          Length = 912

 Score =  107 bits (268), Expect = 3e-23
 Identities = 73/238 (30%), Positives = 118/238 (49%), Gaps = 29/238 (12%)
 Frame = +1

Query: 4    KTGKTVAIKVIKNFGFDSDNERELDN----LKKLSGENIVQLIDFIIKYNTAYLIMELCK 171
            KTG+ VAIK+I    F +  E +L N    L+ L    +V L          +++ME   
Sbjct: 604  KTGRDVAIKIIDKLRFPTKQESQLRNEVAILQNLHHPGVVNLECMFETPERVFVVMEKLH 663

Query: 172  GDV------SETGKLTGPKLKDFIQQTTTGLKIIHDKGMIHRDIKPQNILHVTKGKRTIY 333
            GD+      SE G+L     K  I Q    L+ +H K ++H D+KP+N+L  +       
Sbjct: 664  GDMLEMILSSEKGRLPEHITKFLITQILVALRHLHFKNIVHCDLKPENVLLASADPFPQV 723

Query: 334  KLTDFGLSKMI-SRTHRMTKCGTPVFMAPEVAEGTEANSSADIWSLGITFCYMISGDI-- 504
            KL DFG +++I  ++ R +  GTP ++APEV      N S D+WS+G+     +SG    
Sbjct: 724  KLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLRNKGYNRSLDMWSVGVIIYVSLSGTFPF 783

Query: 505  -KDLGYEDKTKG---------------DLKDLISKMVKEKFRERITVDQILSHPYLRN 630
             +D    D+ +                +  DLI+ +++ K R+R +VD+ LSHP+L++
Sbjct: 784  NEDEDIHDQIQNAAFMYPPNPWKEISHEAIDLINNLLQVKMRKRYSVDKTLSHPWLQD 841
>sp|O94806|KPCN_HUMAN Protein kinase C, nu type (nPKC-nu) (Protein kinase EPK2)
          Length = 890

 Score =  107 bits (268), Expect = 3e-23
 Identities = 74/238 (31%), Positives = 116/238 (48%), Gaps = 29/238 (12%)
 Frame = +1

Query: 4    KTGKTVAIKVIKNFGFDSDNERELDN----LKKLSGENIVQLIDFIIKYNTAYLIMELCK 171
            KTG+ VAIKVI    F +  E +L N    L+ L    IV L          +++ME   
Sbjct: 597  KTGRDVAIKVIDKMRFPTKQESQLRNEVAILQNLHHPGIVNLECMFETPERVFVVMEKLH 656

Query: 172  GDV------SETGKLTGPKLKDFIQQTTTGLKIIHDKGMIHRDIKPQNILHVTKGKRTIY 333
            GD+      SE  +L     K  + Q    L+ +H K ++H D+KP+N+L  +       
Sbjct: 657  GDMLEMILSSEKSRLPERITKFMVTQILVALRNLHFKNIVHCDLKPENVLLASAEPFPQV 716

Query: 334  KLTDFGLSKMI-SRTHRMTKCGTPVFMAPEVAEGTEANSSADIWSLGITFCYMISGDIKD 510
            KL DFG +++I  ++ R +  GTP ++APEV      N S D+WS+G+     +SG    
Sbjct: 717  KLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLRSKGYNRSLDMWSVGVIIYVSLSGTFPF 776

Query: 511  LGYED------------------KTKGDLKDLISKMVKEKFRERITVDQILSHPYLRN 630
               ED                  +  G+  DLI+ +++ K R+R +VD+ LSHP+L++
Sbjct: 777  NEDEDINDQIQNAAFMYPPNPWREISGEAIDLINNLLQVKMRKRYSVDKSLSHPWLQD 834
>sp|Q8ICR0|CDPK2_PLAF7 Calcium-dependent protein kinase 2 (PfCDPK2)
          Length = 509

 Score =  107 bits (268), Expect = 3e-23
 Identities = 71/234 (30%), Positives = 115/234 (49%), Gaps = 28/234 (11%)
 Frame = +1

Query: 7   TGKTVAIKVIKNFGFDSDNE--RELDNLKKLSGENIVQLIDFIIKYNTAYLIMELCKG-- 174
           T +  AIK  K     + N   +E++ +KKL   NIV+L +     N  YLIMELC G  
Sbjct: 94  TNQLYAIKEEKKDRLKNINRFFQEIEIMKKLDHPNIVKLYETYENDNYIYLIMELCSGRE 153

Query: 175 ---DVSETGKLTGPKLKDFIQQTTTGLKIIHDKGMIHRDIKPQNILHVTKGKRTIYKLTD 345
               + E G  T       ++Q  + +  +H   ++HRD+KP+N L  ++ K ++ K+ D
Sbjct: 154 LFDSIIENGSFTEKNAATIMKQIFSAIFYLHSLNIVHRDLKPENFLFQSENKDSLLKIID 213

Query: 346 FGLSKMI-SRTHRMTKCGTPVFMAPEVAEGTEANSSADIWSLGITFCYMISGDIKDLGYE 522
           FGLSK + +     TK GTP ++AP+V +G + +   DIWS G+    ++ G     G  
Sbjct: 214 FGLSKNLGTGEFTTTKAGTPYYVAPQVLDG-KYDKKCDIWSSGVIMYTLLCGYPPFYGDT 272

Query: 523 D--------------------KTKGDLKDLISKMVKEKFRERITVDQILSHPYL 624
           D                        D K+LI+K++     ER T+++ L+HP++
Sbjct: 273 DNEVLKKVKKGEFCFYENDWGSISSDAKNLITKLLTYNPNERCTIEEALNHPWI 326
>sp|O15865|CDPK2_PLAFK Calcium-dependent protein kinase 2 (PfCDPK2)
          Length = 513

 Score =  107 bits (268), Expect = 3e-23
 Identities = 71/234 (30%), Positives = 115/234 (49%), Gaps = 28/234 (11%)
 Frame = +1

Query: 7   TGKTVAIKVIKNFGFDSDNE--RELDNLKKLSGENIVQLIDFIIKYNTAYLIMELCKG-- 174
           T +  AIK  K     + N   +E++ +KKL   NIV+L +     N  YLIMELC G  
Sbjct: 94  TNQLYAIKEEKKDRLKNINRFFQEIEIMKKLDHPNIVKLYETYENDNYIYLIMELCSGRE 153

Query: 175 ---DVSETGKLTGPKLKDFIQQTTTGLKIIHDKGMIHRDIKPQNILHVTKGKRTIYKLTD 345
               + E G  T       ++Q  + +  +H   ++HRD+KP+N L  ++ K ++ K+ D
Sbjct: 154 LFDSIIENGSFTEKNAATIMKQIFSAIFYLHSLNIVHRDLKPENFLFQSENKDSLLKIID 213

Query: 346 FGLSKMI-SRTHRMTKCGTPVFMAPEVAEGTEANSSADIWSLGITFCYMISGDIKDLGYE 522
           FGLSK + +     TK GTP ++AP+V +G + +   DIWS G+    ++ G     G  
Sbjct: 214 FGLSKNLGTGEFTTTKAGTPYYVAPQVLDG-KYDKKCDIWSSGVIMYTLLCGYPPFYGDT 272

Query: 523 D--------------------KTKGDLKDLISKMVKEKFRERITVDQILSHPYL 624
           D                        D K+LI+K++     ER T+++ L+HP++
Sbjct: 273 DNEVLKKVKKGEFCFYENDWGSISSDAKNLITKLLTYNPNERCTIEEALNHPWI 326
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 86,251,166
Number of Sequences: 369166
Number of extensions: 1678009
Number of successful extensions: 8609
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6091
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6623
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8598109270
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)