Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_01805 (238 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q9NI63|PMYT1_DROME Membrane-associated tyrosine-and thre... 33 0.27 sp|P47810|WEE1_MOUSE Wee1-like protein kinase 32 0.46 sp|Q10407|MKH1_SCHPO MAP kinase kinase kinase mkh1 32 0.46 sp|Q63802|WEE1_RAT Wee1-like protein kinase 30 1.7 sp|P54936|LIN2_CAEEL Abnormal cell lineage protein 2 (Prote... 30 2.3 sp|P30291|WEE1_HUMAN Wee1-like protein kinase (WEE1hu) 30 2.3 sp|Q8VCR8|MYLK2_MOUSE Myosin light chain kinase 2, skeletal... 29 3.9 sp|Q9DBQ7|PACE1_MOUSE Protein-associating with the carboxyl... 28 5.1 sp|P20689|MYLK2_RAT Myosin light chain kinase 2, skeletal/c... 28 6.6 sp|O14733|MP2K7_HUMAN Dual specificity mitogen-activated pr... 28 6.6
>sp|Q9NI63|PMYT1_DROME Membrane-associated tyrosine-and threonine-specific cdc2-inhibitory kinase (Myt1 kinase) (dMyt1) Length = 533 Score = 32.7 bits (73), Expect = 0.27 Identities = 13/29 (44%), Positives = 22/29 (75%) Frame = +2 Query: 62 ISETMQSFIRALLNPDQSRRPRADNLLNH 148 IS +QS I++++ PD ++RP A+ LL+H Sbjct: 320 ISLELQSVIKSMMKPDPAQRPTAEQLLSH 348
>sp|P47810|WEE1_MOUSE Wee1-like protein kinase Length = 646 Score = 32.0 bits (71), Expect = 0.46 Identities = 12/33 (36%), Positives = 21/33 (63%) Frame = +2 Query: 56 QPISETMQSFIRALLNPDQSRRPRADNLLNHSI 154 Q +S+ + +R +++PD RRP A L+ HS+ Sbjct: 535 QVLSQEVTELLRVMIHPDPERRPSAMELVKHSV 567
>sp|Q10407|MKH1_SCHPO MAP kinase kinase kinase mkh1 Length = 1116 Score = 32.0 bits (71), Expect = 0.46 Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 3/63 (4%) Frame = +2 Query: 2 VAVMNKIVTTKKIECTPCQPISETMQS---FIRALLNPDQSRRPRADNLLNHSIFNNCDE 172 + M K+ T KK P + +S+ F+ A + RP A+ LLNH F CDE Sbjct: 1040 IQAMFKLGTEKKAPPIPSELVSQVSPEAIQFLNACFTVNADVRPTAEELLNHP-FMKCDE 1098 Query: 173 FYS 181 ++ Sbjct: 1099 EFN 1101
>sp|Q63802|WEE1_RAT Wee1-like protein kinase Length = 646 Score = 30.0 bits (66), Expect = 1.7 Identities = 11/33 (33%), Positives = 21/33 (63%) Frame = +2 Query: 56 QPISETMQSFIRALLNPDQSRRPRADNLLNHSI 154 Q +S+ + ++ +++PD RRP A L+ HS+ Sbjct: 535 QVLSQELTELLKVMIHPDPERRPSAMVLVKHSV 567
>sp|P54936|LIN2_CAEEL Abnormal cell lineage protein 2 (Protein lin-2) Length = 961 Score = 29.6 bits (65), Expect = 2.3 Identities = 13/29 (44%), Positives = 19/29 (65%) Frame = +2 Query: 62 ISETMQSFIRALLNPDQSRRPRADNLLNH 148 ISE+ ++ +R +LN D S+R A LNH Sbjct: 250 ISESARNLVRRMLNADPSKRISAKEALNH 278
>sp|P30291|WEE1_HUMAN Wee1-like protein kinase (WEE1hu) Length = 646 Score = 29.6 bits (65), Expect = 2.3 Identities = 11/33 (33%), Positives = 20/33 (60%) Frame = +2 Query: 56 QPISETMQSFIRALLNPDQSRRPRADNLLNHSI 154 Q +S+ ++ +++PD RRP A L+ HS+ Sbjct: 536 QVLSQEFTELLKVMIHPDPERRPSAMALVKHSV 568
>sp|Q8VCR8|MYLK2_MOUSE Myosin light chain kinase 2, skeletal/cardiac muscle (MLCK2) Length = 240 Score = 28.9 bits (63), Expect = 3.9 Identities = 14/39 (35%), Positives = 20/39 (51%) Frame = +2 Query: 56 QPISETMQSFIRALLNPDQSRRPRADNLLNHSIFNNCDE 172 + +S+ + F+ LL DQS R A+ L H NN E Sbjct: 151 EAVSDEAKDFVSNLLTKDQSARMSAEQCLAHPWLNNLAE 189
>sp|Q9DBQ7|PACE1_MOUSE Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin-binding protein PACE-1) (SCY1-like protein 3) Length = 735 Score = 28.5 bits (62), Expect = 5.1 Identities = 14/34 (41%), Positives = 17/34 (50%) Frame = +2 Query: 62 ISETMQSFIRALLNPDQSRRPRADNLLNHSIFNN 163 +S +Q ALLNP RP LL+H F N Sbjct: 214 LSSFLQILHSALLNPMPECRPALSTLLSHDFFRN 247
>sp|P20689|MYLK2_RAT Myosin light chain kinase 2, skeletal/cardiac muscle (MLCK2) Length = 610 Score = 28.1 bits (61), Expect = 6.6 Identities = 13/39 (33%), Positives = 20/39 (51%) Frame = +2 Query: 56 QPISETMQSFIRALLNPDQSRRPRADNLLNHSIFNNCDE 172 + +S+ + F+ L+ DQS R A+ L H NN E Sbjct: 521 EAVSDEAKDFVSNLITKDQSARMSAEQCLAHPWLNNLAE 559
>sp|O14733|MP2K7_HUMAN Dual specificity mitogen-activated protein kinase kinase 7 (MAP kinase kinase 7) (MAPKK 7) (MAPK/ERK kinase 7) (JNK-activating kinase 2) (c-Jun N-terminal kinase kinase 2) (JNK kinase 2) (JNKK 2) Length = 419 Score = 28.1 bits (61), Expect = 6.6 Identities = 12/29 (41%), Positives = 17/29 (58%) Frame = +2 Query: 65 SETMQSFIRALLNPDQSRRPRADNLLNHS 151 S QSF++ L D +RP+ + LL HS Sbjct: 350 SGDFQSFVKDCLTKDHRKRPKYNKLLEHS 378
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 22,133,997 Number of Sequences: 369166 Number of extensions: 306590 Number of successful extensions: 752 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 749 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 752 length of database: 68,354,980 effective HSP length: 49 effective length of database: 59,302,965 effective search space used: 1719785985 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)