Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_01786 (370 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q99PW8|KIF17_MOUSE Kinesin-like protein KIF17 (MmKIF17) 35 0.041 sp|P41511|TOP1_USTMA DNA topoisomerase I 35 0.054 sp|Q96L73|NSD1_HUMAN Histone-lysine N-methyltransferase, H3... 34 0.092 sp|O76041|NEBL_HUMAN Nebulette (Actin-binding Z-disk protein) 34 0.12 sp|Q5B0V6|AKR1_EMENI Palmitoyltransferase AKR1 (Ankyrin rep... 33 0.16 sp|Q9PP04|AMPA_CAMJE Probable cytosol aminopeptidase (Leuci... 33 0.27 sp|P35209|SPT21_YEAST SPT21 protein 32 0.46 sp|P25439|BRM_DROME Homeotic gene regulator (Brahma protein) 31 0.78 sp|P23731|IFEB_ASCSU Intermediate filament protein B (IF-B) 31 1.0 sp|O33600|RAD50_SULAC DNA double-strand break repair rad50 ... 31 1.0
>sp|Q99PW8|KIF17_MOUSE Kinesin-like protein KIF17 (MmKIF17) Length = 1038 Score = 35.4 bits (80), Expect = 0.041 Identities = 30/96 (31%), Positives = 46/96 (47%) Frame = +2 Query: 38 ELRLSNSEMKNEIIPEIPRIYDRSQNSQDSETFYKNIKSLLQQIQDKKRVDSNYQNQEMI 217 E++ SE + E I + I + +DS F + LL+Q+Q R D NY N E I Sbjct: 837 EIKDLQSEFQLEKIDYLATI---RRQERDSMLF----QQLLEQVQPLIRRDCNYSNLEKI 889 Query: 218 NPKSNSEEANSITKVNYADPKIIRKVLKVAKRRTND 325 +S+ +E N K+ DP I++ L V T + Sbjct: 890 RRESSWDEDNGFWKI--PDPIILKTSLPVVPTGTQN 923
>sp|P41511|TOP1_USTMA DNA topoisomerase I Length = 1019 Score = 35.0 bits (79), Expect = 0.054 Identities = 23/86 (26%), Positives = 41/86 (47%) Frame = +2 Query: 68 NEIIPEIPRIYDRSQNSQDSETFYKNIKSLLQQIQDKKRVDSNYQNQEMINPKSNSEEAN 247 NE + + +++ S F + K +L + + K+ Q E++N + S+ A Sbjct: 761 NETAKRLEKERKTNKSQATSCNFVSSAKKILSKYEMIKK-----QEAELVNKNNTSDVAL 815 Query: 248 SITKVNYADPKIIRKVLKVAKRRTND 325 S +K+NY DP+I LK R +D Sbjct: 816 STSKLNYIDPRITLAWLKEWDDRLSD 841
>sp|Q96L73|NSD1_HUMAN Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor binding SET domain containing protein 1) (NR-binding SET domain containing protein) (Androgen receptor-associated coregulator 267) Length = 2696 Score = 34.3 bits (77), Expect = 0.092 Identities = 29/112 (25%), Positives = 54/112 (48%), Gaps = 5/112 (4%) Frame = +2 Query: 26 LDPAELRLSNSEMKNEIIPEIPRIYDRSQN----SQDSETFYKNIKSLLQQIQDKKR-VD 190 LDP E +SE N ++ EIP +DR++N ++ + Y + +++ K++ + Sbjct: 649 LDPIE---HSSESDNSVL-EIPDAFDRTENMLSMQKNEKIKYSRFAATNTRVKAKQKPLI 704 Query: 191 SNYQNQEMINPKSNSEEANSITKVNYADPKIIRKVLKVAKRRTNDWVWLKFD 346 SN ++ ++E ++VN +D K V K TND + KF+ Sbjct: 705 SNSHTDHLMGCTKSAEPGTETSQVNLSDLKASTLVHKPQSDFTNDALSPKFN 756
>sp|O76041|NEBL_HUMAN Nebulette (Actin-binding Z-disk protein) Length = 1014 Score = 33.9 bits (76), Expect = 0.12 Identities = 29/98 (29%), Positives = 44/98 (44%) Frame = +2 Query: 29 DPAELRLSNSEMKNEIIPEIPRIYDRSQNSQDSETFYKNIKSLLQQIQDKKRVDSNYQNQ 208 D AE LSN + PEI RI QN S FYK ++D ++ +NQ Sbjct: 562 DEAEKMLSNYSTIADT-PEIQRIKTTQQNI--SAVFYKKEVGAGTAVKDSPEIERVKKNQ 618 Query: 209 EMINPKSNSEEANSITKVNYADPKIIRKVLKVAKRRTN 322 + I+ EE T + +DP +++V + K +N Sbjct: 619 QNISSVKYKEEIKHATAI--SDPPELKRVKENQKNISN 654
>sp|Q5B0V6|AKR1_EMENI Palmitoyltransferase AKR1 (Ankyrin repeat-containing protein AKR1) Length = 737 Score = 33.5 bits (75), Expect = 0.16 Identities = 20/70 (28%), Positives = 36/70 (51%) Frame = +2 Query: 14 PSIALDPAELRLSNSEMKNEIIPEIPRIYDRSQNSQDSETFYKNIKSLLQQIQDKKRVDS 193 P +A D A + LS+ + + IP D Q ++ E S++Q++ D+K+ + Sbjct: 38 PKVATDDASVELSSMKSERSPAKSIPLGEDIMQVARIGEV------SVMQKLFDEKKFTA 91 Query: 194 NYQNQEMINP 223 NY ++E I P Sbjct: 92 NYSDEEGITP 101
>sp|Q9PP04|AMPA_CAMJE Probable cytosol aminopeptidase (Leucine aminopeptidase) (LAP) (Leucyl aminopeptidase) Length = 483 Score = 32.7 bits (73), Expect = 0.27 Identities = 26/104 (25%), Positives = 48/104 (46%), Gaps = 5/104 (4%) Frame = +2 Query: 20 IALDPAELRLSNSEMKNEIIPEIPRIYDRSQNSQDSETFYKNIKSLLQQIQDKKRVDSNY 199 I L+ E+ + + I+ EIP IY + ++D++ K K+++ +I D+K + Sbjct: 149 IGLERGEILANATNFTKNIVNEIPEIYTPLKMAEDAQNLAKENKNIICKIYDEKFL---- 204 Query: 200 QNQEMINPKSNSEEANSITKVNYAD---PKIIRKVLKV--AKRR 316 E+ N+ VN+A P++I K AK+R Sbjct: 205 ----------AKEKMNAFLAVNHASVHPPRLIHLSYKAKNAKKR 238
>sp|P35209|SPT21_YEAST SPT21 protein Length = 758 Score = 32.0 bits (71), Expect = 0.46 Identities = 27/108 (25%), Positives = 47/108 (43%), Gaps = 14/108 (12%) Frame = +2 Query: 5 NPKPSIALDPAELRLSNSEMK---NEIIPEIPRIYDRS--QNSQDSETFYKNI------- 148 +P P+ + + ELR+ +K +EI P + D ++ D +Y++I Sbjct: 40 SPFPTDSNEQTELRIGAIHLKTILHEIYLNSPEVLDHDTLKDGYDYNLYYRDICEVDEPL 99 Query: 149 --KSLLQQIQDKKRVDSNYQNQEMINPKSNSEEANSITKVNYADPKII 286 LL ++ K +S YQ E + SEE + +T+ Y D I Sbjct: 100 VSLGLLSGLRKKFHKNSPYQYTENNIGEEESEERDEVTEEEYEDESFI 147
>sp|P25439|BRM_DROME Homeotic gene regulator (Brahma protein) Length = 1638 Score = 31.2 bits (69), Expect = 0.78 Identities = 17/58 (29%), Positives = 31/58 (53%) Frame = +2 Query: 143 NIKSLLQQIQDKKRVDSNYQNQEMINPKSNSEEANSITKVNYADPKIIRKVLKVAKRR 316 +IK +LQ+I+D K D N ++ + N++ N + Y D ++KV A++R Sbjct: 1472 DIKKILQRIEDCKYADLNELEKDFMQLCQNAQIYNEEASLIYLDSIALQKVFVGARQR 1529
>sp|P23731|IFEB_ASCSU Intermediate filament protein B (IF-B) Length = 589 Score = 30.8 bits (68), Expect = 1.0 Identities = 23/76 (30%), Positives = 37/76 (48%), Gaps = 5/76 (6%) Frame = +2 Query: 20 IALDPAELRLSNSEMKNEIIPEIPRIYDR-----SQNSQDSETFYKNIKSLLQQIQDKKR 184 +A PA+ R KNE+ I I D Q QD E++YK S +Q ++ Sbjct: 272 LAQAPADTR---EFFKNELALAIRDIKDEYDYIAKQGKQDMESWYKLKVSEVQGSANRAN 328 Query: 185 VDSNYQNQEMINPKSN 232 ++S+YQ +E+ + N Sbjct: 329 MESSYQREEVKRMRDN 344
>sp|O33600|RAD50_SULAC DNA double-strand break repair rad50 ATPase Length = 886 Score = 30.8 bits (68), Expect = 1.0 Identities = 15/73 (20%), Positives = 35/73 (47%) Frame = +2 Query: 104 RSQNSQDSETFYKNIKSLLQQIQDKKRVDSNYQNQEMINPKSNSEEANSITKVNYADPKI 283 R + ++ E Y+ I+ +++++K++ + + K+ + N I K+NY D + Sbjct: 327 RKKELEEKEKQYEEIEKRKKELEEKEKQYEEIEKRLTYVLKNIERQKNEIEKLNYVDTQD 386 Query: 284 IRKVLKVAKRRTN 322 + +K R N Sbjct: 387 LENKIKDVSDRIN 399
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 29,909,609 Number of Sequences: 369166 Number of extensions: 394176 Number of successful extensions: 1702 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 1668 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 1701 length of database: 68,354,980 effective HSP length: 89 effective length of database: 51,913,565 effective search space used: 1713147645 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)