Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_010_B23
(370 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q99PW8|KIF17_MOUSE Kinesin-like protein KIF17 (MmKIF17) 35 0.041
sp|P41511|TOP1_USTMA DNA topoisomerase I 35 0.054
sp|Q96L73|NSD1_HUMAN Histone-lysine N-methyltransferase, H3... 34 0.092
sp|O76041|NEBL_HUMAN Nebulette (Actin-binding Z-disk protein) 34 0.12
sp|Q5B0V6|AKR1_EMENI Palmitoyltransferase AKR1 (Ankyrin rep... 33 0.16
sp|Q9PP04|AMPA_CAMJE Probable cytosol aminopeptidase (Leuci... 33 0.27
sp|P35209|SPT21_YEAST SPT21 protein 32 0.46
sp|P25439|BRM_DROME Homeotic gene regulator (Brahma protein) 31 0.78
sp|P23731|IFEB_ASCSU Intermediate filament protein B (IF-B) 31 1.0
sp|O33600|RAD50_SULAC DNA double-strand break repair rad50 ... 31 1.0
>sp|Q99PW8|KIF17_MOUSE Kinesin-like protein KIF17 (MmKIF17)
Length = 1038
Score = 35.4 bits (80), Expect = 0.041
Identities = 30/96 (31%), Positives = 46/96 (47%)
Frame = +2
Query: 38 ELRLSNSEMKNEIIPEIPRIYDRSQNSQDSETFYKNIKSLLQQIQDKKRVDSNYQNQEMI 217
E++ SE + E I + I + +DS F + LL+Q+Q R D NY N E I
Sbjct: 837 EIKDLQSEFQLEKIDYLATI---RRQERDSMLF----QQLLEQVQPLIRRDCNYSNLEKI 889
Query: 218 NPKSNSEEANSITKVNYADPKIIRKVLKVAKRRTND 325
+S+ +E N K+ DP I++ L V T +
Sbjct: 890 RRESSWDEDNGFWKI--PDPIILKTSLPVVPTGTQN 923
>sp|P41511|TOP1_USTMA DNA topoisomerase I
Length = 1019
Score = 35.0 bits (79), Expect = 0.054
Identities = 23/86 (26%), Positives = 41/86 (47%)
Frame = +2
Query: 68 NEIIPEIPRIYDRSQNSQDSETFYKNIKSLLQQIQDKKRVDSNYQNQEMINPKSNSEEAN 247
NE + + +++ S F + K +L + + K+ Q E++N + S+ A
Sbjct: 761 NETAKRLEKERKTNKSQATSCNFVSSAKKILSKYEMIKK-----QEAELVNKNNTSDVAL 815
Query: 248 SITKVNYADPKIIRKVLKVAKRRTND 325
S +K+NY DP+I LK R +D
Sbjct: 816 STSKLNYIDPRITLAWLKEWDDRLSD 841
>sp|Q96L73|NSD1_HUMAN Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20
specific (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear
receptor binding SET domain containing protein 1)
(NR-binding SET domain containing protein) (Androgen
receptor-associated coregulator 267)
Length = 2696
Score = 34.3 bits (77), Expect = 0.092
Identities = 29/112 (25%), Positives = 54/112 (48%), Gaps = 5/112 (4%)
Frame = +2
Query: 26 LDPAELRLSNSEMKNEIIPEIPRIYDRSQN----SQDSETFYKNIKSLLQQIQDKKR-VD 190
LDP E +SE N ++ EIP +DR++N ++ + Y + +++ K++ +
Sbjct: 649 LDPIE---HSSESDNSVL-EIPDAFDRTENMLSMQKNEKIKYSRFAATNTRVKAKQKPLI 704
Query: 191 SNYQNQEMINPKSNSEEANSITKVNYADPKIIRKVLKVAKRRTNDWVWLKFD 346
SN ++ ++E ++VN +D K V K TND + KF+
Sbjct: 705 SNSHTDHLMGCTKSAEPGTETSQVNLSDLKASTLVHKPQSDFTNDALSPKFN 756
>sp|O76041|NEBL_HUMAN Nebulette (Actin-binding Z-disk protein)
Length = 1014
Score = 33.9 bits (76), Expect = 0.12
Identities = 29/98 (29%), Positives = 44/98 (44%)
Frame = +2
Query: 29 DPAELRLSNSEMKNEIIPEIPRIYDRSQNSQDSETFYKNIKSLLQQIQDKKRVDSNYQNQ 208
D AE LSN + PEI RI QN S FYK ++D ++ +NQ
Sbjct: 562 DEAEKMLSNYSTIADT-PEIQRIKTTQQNI--SAVFYKKEVGAGTAVKDSPEIERVKKNQ 618
Query: 209 EMINPKSNSEEANSITKVNYADPKIIRKVLKVAKRRTN 322
+ I+ EE T + +DP +++V + K +N
Sbjct: 619 QNISSVKYKEEIKHATAI--SDPPELKRVKENQKNISN 654
>sp|Q5B0V6|AKR1_EMENI Palmitoyltransferase AKR1 (Ankyrin repeat-containing protein AKR1)
Length = 737
Score = 33.5 bits (75), Expect = 0.16
Identities = 20/70 (28%), Positives = 36/70 (51%)
Frame = +2
Query: 14 PSIALDPAELRLSNSEMKNEIIPEIPRIYDRSQNSQDSETFYKNIKSLLQQIQDKKRVDS 193
P +A D A + LS+ + + IP D Q ++ E S++Q++ D+K+ +
Sbjct: 38 PKVATDDASVELSSMKSERSPAKSIPLGEDIMQVARIGEV------SVMQKLFDEKKFTA 91
Query: 194 NYQNQEMINP 223
NY ++E I P
Sbjct: 92 NYSDEEGITP 101
>sp|Q9PP04|AMPA_CAMJE Probable cytosol aminopeptidase (Leucine aminopeptidase) (LAP)
(Leucyl aminopeptidase)
Length = 483
Score = 32.7 bits (73), Expect = 0.27
Identities = 26/104 (25%), Positives = 48/104 (46%), Gaps = 5/104 (4%)
Frame = +2
Query: 20 IALDPAELRLSNSEMKNEIIPEIPRIYDRSQNSQDSETFYKNIKSLLQQIQDKKRVDSNY 199
I L+ E+ + + I+ EIP IY + ++D++ K K+++ +I D+K +
Sbjct: 149 IGLERGEILANATNFTKNIVNEIPEIYTPLKMAEDAQNLAKENKNIICKIYDEKFL---- 204
Query: 200 QNQEMINPKSNSEEANSITKVNYAD---PKIIRKVLKV--AKRR 316
E+ N+ VN+A P++I K AK+R
Sbjct: 205 ----------AKEKMNAFLAVNHASVHPPRLIHLSYKAKNAKKR 238
>sp|P35209|SPT21_YEAST SPT21 protein
Length = 758
Score = 32.0 bits (71), Expect = 0.46
Identities = 27/108 (25%), Positives = 47/108 (43%), Gaps = 14/108 (12%)
Frame = +2
Query: 5 NPKPSIALDPAELRLSNSEMK---NEIIPEIPRIYDRS--QNSQDSETFYKNI------- 148
+P P+ + + ELR+ +K +EI P + D ++ D +Y++I
Sbjct: 40 SPFPTDSNEQTELRIGAIHLKTILHEIYLNSPEVLDHDTLKDGYDYNLYYRDICEVDEPL 99
Query: 149 --KSLLQQIQDKKRVDSNYQNQEMINPKSNSEEANSITKVNYADPKII 286
LL ++ K +S YQ E + SEE + +T+ Y D I
Sbjct: 100 VSLGLLSGLRKKFHKNSPYQYTENNIGEEESEERDEVTEEEYEDESFI 147
>sp|P25439|BRM_DROME Homeotic gene regulator (Brahma protein)
Length = 1638
Score = 31.2 bits (69), Expect = 0.78
Identities = 17/58 (29%), Positives = 31/58 (53%)
Frame = +2
Query: 143 NIKSLLQQIQDKKRVDSNYQNQEMINPKSNSEEANSITKVNYADPKIIRKVLKVAKRR 316
+IK +LQ+I+D K D N ++ + N++ N + Y D ++KV A++R
Sbjct: 1472 DIKKILQRIEDCKYADLNELEKDFMQLCQNAQIYNEEASLIYLDSIALQKVFVGARQR 1529
>sp|P23731|IFEB_ASCSU Intermediate filament protein B (IF-B)
Length = 589
Score = 30.8 bits (68), Expect = 1.0
Identities = 23/76 (30%), Positives = 37/76 (48%), Gaps = 5/76 (6%)
Frame = +2
Query: 20 IALDPAELRLSNSEMKNEIIPEIPRIYDR-----SQNSQDSETFYKNIKSLLQQIQDKKR 184
+A PA+ R KNE+ I I D Q QD E++YK S +Q ++
Sbjct: 272 LAQAPADTR---EFFKNELALAIRDIKDEYDYIAKQGKQDMESWYKLKVSEVQGSANRAN 328
Query: 185 VDSNYQNQEMINPKSN 232
++S+YQ +E+ + N
Sbjct: 329 MESSYQREEVKRMRDN 344
>sp|O33600|RAD50_SULAC DNA double-strand break repair rad50 ATPase
Length = 886
Score = 30.8 bits (68), Expect = 1.0
Identities = 15/73 (20%), Positives = 35/73 (47%)
Frame = +2
Query: 104 RSQNSQDSETFYKNIKSLLQQIQDKKRVDSNYQNQEMINPKSNSEEANSITKVNYADPKI 283
R + ++ E Y+ I+ +++++K++ + + K+ + N I K+NY D +
Sbjct: 327 RKKELEEKEKQYEEIEKRKKELEEKEKQYEEIEKRLTYVLKNIERQKNEIEKLNYVDTQD 386
Query: 284 IRKVLKVAKRRTN 322
+ +K R N
Sbjct: 387 LENKIKDVSDRIN 399
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,909,609
Number of Sequences: 369166
Number of extensions: 394176
Number of successful extensions: 1702
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1668
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1701
length of database: 68,354,980
effective HSP length: 89
effective length of database: 51,913,565
effective search space used: 1713147645
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)