Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_01753 (258 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q9UPZ9|ICK_HUMAN Serine/threonine-protein kinase ICK (In... 29 2.9 sp|Q9JKV2|ICK_MOUSE Serine/threonine-protein kinase ICK (In... 29 2.9 sp|Q62726|ICK_RAT Serine/threonine-protein kinase ICK (Inte... 29 2.9 sp|P20793|MAK_RAT Serine/threonine-protein kinase MAK (Male... 29 3.8 sp|Q04859|MAK_MOUSE Serine/threonine-protein kinase MAK (Ma... 29 3.8 sp|Q8CPF0|MUTS_STAES DNA mismatch repair protein mutS >gi|7... 28 6.5 sp|P20794|MAK_HUMAN Serine/threonine-protein kinase MAK (Ma... 28 8.5 sp|Q8VIM5|MYCD_MOUSE Myocardin (SRF cofactor protein) (Basi... 28 8.5 sp|Q9XSL6|ADA28_MACFA ADAM 28 precursor (A disintegrin and ... 28 8.5 sp|Q9UKQ2|ADA28_HUMAN ADAM 28 precursor (A disintegrin and ... 28 8.5
>sp|Q9UPZ9|ICK_HUMAN Serine/threonine-protein kinase ICK (Intestinal cell kinase) (hICK) (MAK-related kinase) (MRK) (Laryngeal cancer kinase 2) (LCK2) Length = 632 Score = 29.3 bits (64), Expect = 2.9 Identities = 16/40 (40%), Positives = 22/40 (55%), Gaps = 5/40 (12%) Frame = -3 Query: 169 EYYTSRN-----NEITTSVQILQVRGVSKRANWPRGARLA 65 E YT R +EI T +I QV G K+ +WP G +L+ Sbjct: 192 EVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLS 231
>sp|Q9JKV2|ICK_MOUSE Serine/threonine-protein kinase ICK (Intestinal cell kinase) (mICK) (MAK-related kinase) (MRK) Length = 629 Score = 29.3 bits (64), Expect = 2.9 Identities = 16/40 (40%), Positives = 22/40 (55%), Gaps = 5/40 (12%) Frame = -3 Query: 169 EYYTSRN-----NEITTSVQILQVRGVSKRANWPRGARLA 65 E YT R +EI T +I QV G K+ +WP G +L+ Sbjct: 192 EVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLS 231
>sp|Q62726|ICK_RAT Serine/threonine-protein kinase ICK (Intestinal cell kinase) (MAK-related kinase) (MRK) Length = 629 Score = 29.3 bits (64), Expect = 2.9 Identities = 16/40 (40%), Positives = 22/40 (55%), Gaps = 5/40 (12%) Frame = -3 Query: 169 EYYTSRN-----NEITTSVQILQVRGVSKRANWPRGARLA 65 E YT R +EI T +I QV G K+ +WP G +L+ Sbjct: 192 EVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLS 231
>sp|P20793|MAK_RAT Serine/threonine-protein kinase MAK (Male germ cell-associated kinase) Length = 622 Score = 28.9 bits (63), Expect = 3.8 Identities = 15/40 (37%), Positives = 22/40 (55%), Gaps = 5/40 (12%) Frame = -3 Query: 169 EYYTSR-----NNEITTSVQILQVRGVSKRANWPRGARLA 65 E YT R +E+ +I QV G K+++WP G +LA Sbjct: 192 ELYTFRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLA 231
>sp|Q04859|MAK_MOUSE Serine/threonine-protein kinase MAK (Male germ cell-associated kinase) (Protein kinase RCK) Length = 622 Score = 28.9 bits (63), Expect = 3.8 Identities = 15/40 (37%), Positives = 22/40 (55%), Gaps = 5/40 (12%) Frame = -3 Query: 169 EYYTSR-----NNEITTSVQILQVRGVSKRANWPRGARLA 65 E YT R +E+ +I QV G K+++WP G +LA Sbjct: 192 ELYTFRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLA 231
>sp|Q8CPF0|MUTS_STAES DNA mismatch repair protein mutS sp|Q5HPP5|MUTS_STAEQ DNA mismatch repair protein mutS Length = 873 Score = 28.1 bits (61), Expect = 6.5 Identities = 19/62 (30%), Positives = 29/62 (46%), Gaps = 8/62 (12%) Frame = -3 Query: 223 QLRHLESITN*LETGSLD----EYYTSRNNEITTSVQILQVRG----VSKRANWPRGARL 68 Q R L I +E ++D +YY RN E+T S+++ +G + P GAR Sbjct: 228 QKRDLSHIEEVIEYAAVDYMKMDYYAKRNLELTESIRLKSKKGTLLWLMDETKTPMGARR 287 Query: 67 AK 62 K Sbjct: 288 LK 289
>sp|P20794|MAK_HUMAN Serine/threonine-protein kinase MAK (Male germ cell-associated kinase) Length = 623 Score = 27.7 bits (60), Expect = 8.5 Identities = 11/28 (39%), Positives = 18/28 (64%) Frame = -3 Query: 148 NEITTSVQILQVRGVSKRANWPRGARLA 65 +E+ +I QV G K+++WP G +LA Sbjct: 204 SEVDEIFKICQVLGTPKKSDWPEGYQLA 231
>sp|Q8VIM5|MYCD_MOUSE Myocardin (SRF cofactor protein) (Basic SAP coiled-coil transcription activator 2) Length = 935 Score = 27.7 bits (60), Expect = 8.5 Identities = 13/35 (37%), Positives = 21/35 (60%) Frame = -2 Query: 155 AEQ*NHNISSDSAGARCFQTSKLATRRKIG*TSSV 51 A++ NH +SS S+ C Q + L + K+G T S+ Sbjct: 665 AQRENHGVSSPSSSQGCAQMTGLQSSDKVGPTFSI 699
>sp|Q9XSL6|ADA28_MACFA ADAM 28 precursor (A disintegrin and metalloproteinase domain 28) (eMDC II) Length = 776 Score = 27.7 bits (60), Expect = 8.5 Identities = 14/32 (43%), Positives = 18/32 (56%) Frame = -3 Query: 214 HLESITN*LETGSLDEYYTSRNNEITTSVQIL 119 +L+ N L G + YY S EITTS QI+ Sbjct: 72 YLKKNKNLLAPGYTETYYNSTGKEITTSPQIM 103
>sp|Q9UKQ2|ADA28_HUMAN ADAM 28 precursor (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein-L) (MDC-L) (eMDC II) (ADAM23) Length = 775 Score = 27.7 bits (60), Expect = 8.5 Identities = 14/32 (43%), Positives = 18/32 (56%) Frame = -3 Query: 214 HLESITN*LETGSLDEYYTSRNNEITTSVQIL 119 +L+ N L G + YY S EITTS QI+ Sbjct: 71 YLKKNKNLLAPGYTETYYNSTGKEITTSPQIM 102
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 28,174,795 Number of Sequences: 369166 Number of extensions: 462744 Number of successful extensions: 984 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 975 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 984 length of database: 68,354,980 effective HSP length: 56 effective length of database: 58,009,820 effective search space used: 1682284780 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)