Planaria EST Database


DrC_01745

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_01745
         (867 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q68FX0|IDH3B_RAT  Isocitrate dehydrogenase [NAD] subunit ...   259   9e-69
sp|O43837|IDH3B_HUMAN  Isocitrate dehydrogenase [NAD] subuni...   258   1e-68
sp|O77784|IDH3B_BOVIN  Isocitrate dehydrogenase [NAD] subuni...   258   1e-68
sp|Q28479|IDH3B_MACFA  Isocitrate dehydrogenase [NAD] subuni...   254   3e-67
sp|Q5RBT4|IDH3B_PONPY  Isocitrate dehydrogenase [NAD] subuni...   253   5e-67
sp|Q93353|IDH3B_CAEEL  Probable isocitrate dehydrogenase [NA...   251   1e-66
sp|O94229|IDH1_KLULA  Isocitrate dehydrogenase [NAD] subunit...   224   3e-58
sp|P28834|IDH1_YEAST  Isocitrate dehydrogenase [NAD] subunit...   223   4e-58
sp|P41565|IDH3G_RAT  Isocitrate dehydrogenase [NAD] subunit ...   222   1e-57
sp|P41564|IDH3G_MACFA  Isocitrate dehydrogenase [NAD] subuni...   221   2e-57
>sp|Q68FX0|IDH3B_RAT Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial
           precursor (Isocitric dehydrogenase) (NAD(+)-specific
           ICDH)
          Length = 385

 Score =  259 bits (661), Expect = 9e-69
 Identities = 126/240 (52%), Positives = 165/240 (68%)
 Frame = +1

Query: 1   NIDFVVIREQTEGEYSALEHESVPGVVESLKIITKSKSERIAKFAFDFAKKHGRKKVTAV 180
           N+D V+IREQTEGEYS+LEHES  GV+E LKI+T++KS+RIAKFAFD+A K GR KVTAV
Sbjct: 157 NLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRTKSQRIAKFAFDYATKKGRSKVTAV 216

Query: 181 HKANIM*LVMXXXXXXXXXXXXKLGDGLFLESCRNVSKLYPDIKLDDIIVDNCCMQLVSN 360
           HKANIM                KLGDGLFL+ C  V++LYP IK + +I+DNCCMQLV N
Sbjct: 217 HKANIM----------------KLGDGLFLQCCEEVAELYPKIKFETMIIDNCCMQLVQN 260

Query: 361 PQQFDVLVTPNLYGAVVDNXXXXXXXXXXXXXXXSFGYDVAIFEPGSRHPFAMAAGKNIA 540
           P QFDVLV PNLYG ++DN               S+  + A+FE G+RHPFA A G+NIA
Sbjct: 261 PYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEYAVFETGARHPFAQAVGRNIA 320

Query: 541 NPIGLFLSAVGMLHHINMHSQAIQLESAILNVLKDGEVRTEDIGGTNSTTEIVEAIISQV 720
           NP  + LSA  ML H+N+   +  +  A+  V+K G+VRT D+GG ++TT+ ++++I  +
Sbjct: 321 NPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTRDMGGYSTTTDFIKSVIGHL 380
>sp|O43837|IDH3B_HUMAN Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial
           precursor (Isocitric dehydrogenase) (NAD(+)-specific
           ICDH)
          Length = 385

 Score =  258 bits (660), Expect = 1e-68
 Identities = 126/241 (52%), Positives = 166/241 (68%)
 Frame = +1

Query: 1   NIDFVVIREQTEGEYSALEHESVPGVVESLKIITKSKSERIAKFAFDFAKKHGRKKVTAV 180
           N+D V+IREQTEGEYS+LEHES  GV+E LKI+T++KS+RIAKFAFD+A K GR KVTAV
Sbjct: 157 NLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQRIAKFAFDYATKKGRGKVTAV 216

Query: 181 HKANIM*LVMXXXXXXXXXXXXKLGDGLFLESCRNVSKLYPDIKLDDIIVDNCCMQLVSN 360
           HKANIM                KLGDGLFL+ C  V++LYP IK + +I+DNCCMQLV N
Sbjct: 217 HKANIM----------------KLGDGLFLQCCEEVAELYPKIKFETMIIDNCCMQLVQN 260

Query: 361 PQQFDVLVTPNLYGAVVDNXXXXXXXXXXXXXXXSFGYDVAIFEPGSRHPFAMAAGKNIA 540
           P QFDVLV PNLYG ++DN               S+  + A+FE G+RHPFA A G+NIA
Sbjct: 261 PYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEYAVFETGARHPFAQAVGRNIA 320

Query: 541 NPIGLFLSAVGMLHHINMHSQAIQLESAILNVLKDGEVRTEDIGGTNSTTEIVEAIISQV 720
           NP  + LSA  ML H+N+   +  +  A+  V+K G+VRT D+GG ++TT+ ++++I  +
Sbjct: 321 NPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTRDMGGYSTTTDFIKSVIGHL 380

Query: 721 K 723
           +
Sbjct: 381 Q 381
>sp|O77784|IDH3B_BOVIN Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial
           precursor (Isocitric dehydrogenase) (NAD(+)-specific
           ICDH) (NAD(+)-isocitrate dehydrogenase subunit 1) (IDH1)
          Length = 385

 Score =  258 bits (659), Expect = 1e-68
 Identities = 126/240 (52%), Positives = 165/240 (68%)
 Frame = +1

Query: 1   NIDFVVIREQTEGEYSALEHESVPGVVESLKIITKSKSERIAKFAFDFAKKHGRKKVTAV 180
           N+D V+IREQTEGEYS+LEHES  GV+E LKI+T++KS+RIAKFAFD+A K GR KVTAV
Sbjct: 157 NLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRTKSQRIAKFAFDYATKKGRGKVTAV 216

Query: 181 HKANIM*LVMXXXXXXXXXXXXKLGDGLFLESCRNVSKLYPDIKLDDIIVDNCCMQLVSN 360
           HKANIM                KLGDGLFL+ C  V++LYP IK + +I+DNCCMQLV N
Sbjct: 217 HKANIM----------------KLGDGLFLQCCEEVAELYPKIKFEKMIIDNCCMQLVQN 260

Query: 361 PQQFDVLVTPNLYGAVVDNXXXXXXXXXXXXXXXSFGYDVAIFEPGSRHPFAMAAGKNIA 540
           P QFDVLV PNLYG ++DN               S+  + A+FE G+RHPFA A G+NIA
Sbjct: 261 PYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEYAVFETGARHPFAQAVGRNIA 320

Query: 541 NPIGLFLSAVGMLHHINMHSQAIQLESAILNVLKDGEVRTEDIGGTNSTTEIVEAIISQV 720
           NP  + LSA  ML H+N+   +  +  A+  V+K G+VRT D+GG ++TT+ ++++I  +
Sbjct: 321 NPTAMLLSASNMLRHLNLEHHSNMIAEAVKKVIKVGKVRTRDMGGYSTTTDFIKSVIGHL 380
>sp|Q28479|IDH3B_MACFA Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial
           precursor (Isocitric dehydrogenase) (NAD(+)-specific
           ICDH)
          Length = 381

 Score =  254 bits (648), Expect = 3e-67
 Identities = 126/238 (52%), Positives = 161/238 (67%)
 Frame = +1

Query: 1   NIDFVVIREQTEGEYSALEHESVPGVVESLKIITKSKSERIAKFAFDFAKKHGRKKVTAV 180
           N+D V+IREQTEGEYS+LEHES  GV+E LKI+T++KS+RIAKFAFD+A K GR KVTAV
Sbjct: 155 NLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQRIAKFAFDYATKKGRSKVTAV 214

Query: 181 HKANIM*LVMXXXXXXXXXXXXKLGDGLFLESCRNVSKLYPDIKLDDIIVDNCCMQLVSN 360
           HKANIM                KLGDGLFL+ C  V++LYP IK + +I+DNCCMQLV N
Sbjct: 215 HKANIM----------------KLGDGLFLQCCEEVAELYPKIKFETMIIDNCCMQLVQN 258

Query: 361 PQQFDVLVTPNLYGAVVDNXXXXXXXXXXXXXXXSFGYDVAIFEPGSRHPFAMAAGKNIA 540
           P QFDVLV PNLYG ++DN               S+  + A+FE G+RHPFA A G+NIA
Sbjct: 259 PYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEYAVFETGARHPFAQAVGRNIA 318

Query: 541 NPIGLFLSAVGMLHHINMHSQAIQLESAILNVLKDGEVRTEDIGGTNSTTEIVEAIIS 714
           NP  + LSA  ML H+N+   +  +  A+  V+K G+VRT D+GG  +  +  EA+I+
Sbjct: 319 NPTAMLLSASNMLRHLNLEYHSNMIADAVKKVIKVGKVRTSDMGGYATCHDFTEAVIA 376
>sp|Q5RBT4|IDH3B_PONPY Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial
           precursor (Isocitric dehydrogenase) (NAD(+)-specific
           ICDH)
          Length = 385

 Score =  253 bits (646), Expect = 5e-67
 Identities = 124/240 (51%), Positives = 163/240 (67%)
 Frame = +1

Query: 1   NIDFVVIREQTEGEYSALEHESVPGVVESLKIITKSKSERIAKFAFDFAKKHGRKKVTAV 180
           N+D V+IREQTEGE S+LEHES  GV+E LKI+T++KS+RIAKFAFD+A K GR KV AV
Sbjct: 157 NLDLVIIREQTEGECSSLEHESARGVIECLKIVTRAKSQRIAKFAFDYATKKGRSKVIAV 216

Query: 181 HKANIM*LVMXXXXXXXXXXXXKLGDGLFLESCRNVSKLYPDIKLDDIIVDNCCMQLVSN 360
           HKANIM                KLGDGLFL+ C  V++LYP IK + +I+DNCCMQLV N
Sbjct: 217 HKANIM----------------KLGDGLFLQCCEEVAELYPKIKFETMIIDNCCMQLVQN 260

Query: 361 PQQFDVLVTPNLYGAVVDNXXXXXXXXXXXXXXXSFGYDVAIFEPGSRHPFAMAAGKNIA 540
           P QFDVLV PNLYG ++DN               S+  + A+FE G+RHPFA A G+NIA
Sbjct: 261 PYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEYAVFETGARHPFAQAVGRNIA 320

Query: 541 NPIGLFLSAVGMLHHINMHSQAIQLESAILNVLKDGEVRTEDIGGTNSTTEIVEAIISQV 720
           NP  + LSA  ML H+N+   +  +  A+  V+K G+VRT D+GG ++TT+ ++++I  +
Sbjct: 321 NPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTRDMGGYSTTTDFIKSVIGHL 380
>sp|Q93353|IDH3B_CAEEL Probable isocitrate dehydrogenase [NAD] subunit beta, mitochondrial
           precursor (Isocitric dehydrogenase) (NAD(+)-specific
           ICDH)
          Length = 379

 Score =  251 bits (642), Expect = 1e-66
 Identities = 125/241 (51%), Positives = 164/241 (68%)
 Frame = +1

Query: 4   IDFVVIREQTEGEYSALEHESVPGVVESLKIITKSKSERIAKFAFDFAKKHGRKKVTAVH 183
           +DFV++REQTEGEYS+LEHE VPGV+E LKI T++K+ERIAKFAFD+A K GRKKVTAVH
Sbjct: 155 LDFVIVREQTEGEYSSLEHELVPGVIECLKISTRTKAERIAKFAFDYATKTGRKKVTAVH 214

Query: 184 KANIM*LVMXXXXXXXXXXXXKLGDGLFLESCRNVSKLYPDIKLDDIIVDNCCMQLVSNP 363
           KANIM                KLGDGLFL +C  V+K YP I+ + +I+DN CMQLVS P
Sbjct: 215 KANIM----------------KLGDGLFLRTCEGVAKQYPKIQFESMIIDNTCMQLVSKP 258

Query: 364 QQFDVLVTPNLYGAVVDNXXXXXXXXXXXXXXXSFGYDVAIFEPGSRHPFAMAAGKNIAN 543
           +QFDV+V PNLYG ++DN               S G D  IFEPGSRH F  A G++IAN
Sbjct: 259 EQFDVMVMPNLYGNIIDNLAAGLVGGAGVVPGQSVGRDFVIFEPGSRHSFQEAMGRSIAN 318

Query: 544 PIGLFLSAVGMLHHINMHSQAIQLESAILNVLKDGEVRTEDIGGTNSTTEIVEAIISQVK 723
           P  + L A  ML+H+++ +    L  A+ +V+K+G+VRT D+GG  +T +  +A+I + +
Sbjct: 319 PTAMILCAANMLNHLHLDAWGNSLRQAVADVVKEGKVRTRDLGGYATTVDFADAVIDKFR 378

Query: 724 I 726
           I
Sbjct: 379 I 379
>sp|O94229|IDH1_KLULA Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial precursor
           (Isocitric dehydrogenase) (NAD(+)-specific ICDH)
          Length = 361

 Score =  224 bits (570), Expect = 3e-58
 Identities = 118/241 (48%), Positives = 157/241 (65%), Gaps = 1/241 (0%)
 Frame = +1

Query: 1   NIDFVVIREQTEGEYSALEHESVPGVVESLKIITKSKSERIAKFAFDFAKKHGRKKVTAV 180
           NID V+IRE TEGEYS LEHESVPGVVESLKI+T++KSERIA+FAFDFA K+ RK V AV
Sbjct: 134 NIDMVIIRENTEGEYSGLEHESVPGVVESLKIMTRAKSERIARFAFDFALKNNRKSVCAV 193

Query: 181 HKANIM*LVMXXXXXXXXXXXXKLGDGLFLESCRNV-SKLYPDIKLDDIIVDNCCMQLVS 357
           HKANIM                KLGDGLF  +   + +  YP++ + +IIVDN  MQ V+
Sbjct: 194 HKANIM----------------KLGDGLFRNTVNEIGANEYPELDVKNIIVDNASMQAVA 237

Query: 358 NPQQFDVLVTPNLYGAVVDNXXXXXXXXXXXXXXXSFGYDVAIFEPGSRHPFAMAAGKNI 537
            P QFDVLVTPNLYG+++ N               +FG + A+FEPGSRH      G+N+
Sbjct: 238 KPHQFDVLVTPNLYGSILGNIGSALIGGPGLVPGANFGREYAVFEPGSRHVGLDIKGQNV 297

Query: 538 ANPIGLFLSAVGMLHHINMHSQAIQLESAILNVLKDGEVRTEDIGGTNSTTEIVEAIISQ 717
           ANP  + LS+  ML H+ +++ A ++  A  +V+ +G+  T DIGG+ ST+E   A+I +
Sbjct: 298 ANPTAMILSSTLMLRHLGLNAYADRISKATYDVISEGKSTTRDIGGSASTSEFTNAVIEK 357

Query: 718 V 720
           +
Sbjct: 358 L 358
>sp|P28834|IDH1_YEAST Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial precursor
           (Isocitric dehydrogenase) (NAD(+)-specific ICDH)
          Length = 360

 Score =  223 bits (569), Expect = 4e-58
 Identities = 117/241 (48%), Positives = 155/241 (64%), Gaps = 1/241 (0%)
 Frame = +1

Query: 1   NIDFVVIREQTEGEYSALEHESVPGVVESLKIITKSKSERIAKFAFDFAKKHGRKKVTAV 180
           +ID +VIRE TEGE+S LEHESVPGVVESLK++T+ K+ERIA+FAFDFAKK+ RK VTAV
Sbjct: 133 DIDLIVIRENTEGEFSGLEHESVPGVVESLKVMTRPKTERIARFAFDFAKKYNRKSVTAV 192

Query: 181 HKANIM*LVMXXXXXXXXXXXXKLGDGLFLESCRNVS-KLYPDIKLDDIIVDNCCMQLVS 357
           HKANIM                KLGDGLF      +  K YPDI +  IIVDN  MQ V+
Sbjct: 193 HKANIM----------------KLGDGLFRNIITEIGQKEYPDIDVSSIIVDNASMQAVA 236

Query: 358 NPQQFDVLVTPNLYGAVVDNXXXXXXXXXXXXXXXSFGYDVAIFEPGSRHPFAMAAGKNI 537
            P QFDVLVTP++YG ++ N               +FG D A+FEPGSRH      G+N+
Sbjct: 237 KPHQFDVLVTPSMYGTILGNIGAALIGGPGLVAGANFGRDYAVFEPGSRHVGLDIKGQNV 296

Query: 538 ANPIGLFLSAVGMLHHINMHSQAIQLESAILNVLKDGEVRTEDIGGTNSTTEIVEAIISQ 717
           ANP  + LS+  ML+H+ ++  A ++  A+   + +G+  T DIGG++STT+    II++
Sbjct: 297 ANPTAMILSSTLMLNHLGLNEYATRISKAVHETIAEGKHTTRDIGGSSSTTDFTNEIINK 356

Query: 718 V 720
           +
Sbjct: 357 L 357
>sp|P41565|IDH3G_RAT Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial
           precursor (Isocitric dehydrogenase) (NAD(+)-specific
           ICDH)
          Length = 393

 Score =  222 bits (565), Expect = 1e-57
 Identities = 117/242 (48%), Positives = 155/242 (64%)
 Frame = +1

Query: 1   NIDFVVIREQTEGEYSALEHESVPGVVESLKIITKSKSERIAKFAFDFAKKHGRKKVTAV 180
           +ID +++RE TEGEYS+LEHESV GVVESLKIITK+KS RIA++AF  A++ GRKKVTAV
Sbjct: 160 DIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAV 219

Query: 181 HKANIM*LVMXXXXXXXXXXXXKLGDGLFLESCRNVSKLYPDIKLDDIIVDNCCMQLVSN 360
           HKANIM                KLGDGLFL+ CR V+  YP I  D +IVDN  MQLVS 
Sbjct: 220 HKANIM----------------KLGDGLFLQCCREVAARYPQITFDSMIVDNTTMQLVSR 263

Query: 361 PQQFDVLVTPNLYGAVVDNXXXXXXXXXXXXXXXSFGYDVAIFEPGSRHPFAMAAGKNIA 540
           PQQFDV+V PNLYG +V+N               ++G+  A+FE  +R+     A KNIA
Sbjct: 264 PQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIA 323

Query: 541 NPIGLFLSAVGMLHHINMHSQAIQLESAILNVLKDGEVRTEDIGGTNSTTEIVEAIISQV 720
           NP    L++  ML H+ +HS A  +  A+L  + +  + T DIGG  +T++ ++ II  +
Sbjct: 324 NPTATLLASCMMLDHLKLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSQAIQDIIRHI 383

Query: 721 KI 726
           +I
Sbjct: 384 RI 385
>sp|P41564|IDH3G_MACFA Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial
           precursor (Isocitric dehydrogenase) (NAD(+)-specific
           ICDH)
          Length = 355

 Score =  221 bits (564), Expect = 2e-57
 Identities = 116/242 (47%), Positives = 156/242 (64%)
 Frame = +1

Query: 1   NIDFVVIREQTEGEYSALEHESVPGVVESLKIITKSKSERIAKFAFDFAKKHGRKKVTAV 180
           +ID +++RE TEGEYS+LEHESV GVVESLKIITK+KS RIA++AF  A++ GRKKVTAV
Sbjct: 122 DIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAV 181

Query: 181 HKANIM*LVMXXXXXXXXXXXXKLGDGLFLESCRNVSKLYPDIKLDDIIVDNCCMQLVSN 360
           HKANIM                KLGDGLFL+ CR V+  YP I  +++IVDN  MQLVS 
Sbjct: 182 HKANIM----------------KLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSR 225

Query: 361 PQQFDVLVTPNLYGAVVDNXXXXXXXXXXXXXXXSFGYDVAIFEPGSRHPFAMAAGKNIA 540
           PQQFDV+V PNLYG +V+N               ++G+  A+FE  +R+     A KNIA
Sbjct: 226 PQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIA 285

Query: 541 NPIGLFLSAVGMLHHINMHSQAIQLESAILNVLKDGEVRTEDIGGTNSTTEIVEAIISQV 720
           NP    L++  ML H+ +HS A  +  A+L  + +  + T DIGG  +T+E ++ II  +
Sbjct: 286 NPTATLLASCMMLDHLKLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAIQDIIRHI 345

Query: 721 KI 726
           ++
Sbjct: 346 RV 347
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 103,750,133
Number of Sequences: 369166
Number of extensions: 2211049
Number of successful extensions: 7869
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 7054
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7549
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8550075140
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)