Planaria EST Database


DrC_01716

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_01716
         (897 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|O95425|SVIL_HUMAN  Supervillin (Archvillin) (p205/p250)        140   5e-33
sp|Q8K4L3|SVIL_MOUSE  Supervillin (Archvillin) (p205/p250)        138   2e-32
sp|Q28046|ADSV_BOVIN  Adseverin (Scinderin) (SC)                   70   1e-11
sp|Q9Y6U3|ADSV_HUMAN  Adseverin (Scinderin)                        69   2e-11
sp|Q60604|ADSV_MOUSE  Adseverin (Scinderin) (Gelsolin-like p...    68   4e-11
sp|Q62468|VILI_MOUSE  Villin-1                                     67   5e-11
sp|Q07171|GELS_DROME  Gelsolin precursor                           66   1e-10
sp|O88398|AVIL_MOUSE  Advillin (p92) (Actin-binding protein ...    64   4e-10
sp|Q27319|GELS_HOMAM  Gelsolin, cytoplasmic (Actin-depolymer...    64   7e-10
sp|P09327|VILI_HUMAN  Villin-1                                     63   1e-09
>sp|O95425|SVIL_HUMAN Supervillin (Archvillin) (p205/p250)
          Length = 2214

 Score =  140 bits (353), Expect = 5e-33
 Identities = 82/250 (32%), Positives = 137/250 (54%), Gaps = 8/250 (3%)
 Frame = +3

Query: 3    QGISTSITEKTASALLTIDLDKDRTTQIRVKQHHESPAFCRLFGGTMVVHIG-KQQFSEN 179
            QG  ++++EK  SAL+T++LD++R  Q++V Q  E P F + F G MVVH G +++  EN
Sbjct: 1817 QGRHSTVSEKGTSALMTVELDEERGAQVQVLQGKEPPCFLQCFQGGMVVHSGRREEEEEN 1876

Query: 180  V-SKSRLFVIRGEIESEAHFVEVLCESQSLRERGVFLLLNIKRSKCYLWLGNCASAESRS 356
            V S+ RL+ +RGE+  E + +EV C   SLR R   ++LN+ ++  YLW G  A A ++ 
Sbjct: 1877 VQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLWHGCKAQAHTKE 1936

Query: 357  SAFFCIKQLLAKKPIDLRI-TLNDIKIEEIEQGKEPRTFWEDMGIIKKWKSSYIYHD--- 524
                   ++  + P++  + + + + I E ++G EP  FW+ +G   +     +  D   
Sbjct: 1937 VGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRRDRKAYDCMLQDPGS 1996

Query: 525  --LVPIRGWFVSGLTGVFILNEMNYSLCPDGENNIVPAFPLLQATLYKSSQPTLFLIWTP 698
                P R + +S  +G F   E  Y   P    ++V + P LQ  LY + QP LFL+   
Sbjct: 1997 FNFAP-RLFILSSSSGDFAATEFVY---PARAPSVVSSMPFLQEDLYSAPQPALFLVDNH 2052

Query: 699  VHIFIWEGWW 728
              +++W+GWW
Sbjct: 2053 HEVYLWQGWW 2062

 Score = 30.0 bits (66), Expect = 9.1
 Identities = 27/102 (26%), Positives = 44/102 (43%), Gaps = 5/102 (4%)
 Frame = +3

Query: 195  LFVIRGEIESEAHFVEVLCESQSLRERGVFLLLNIKRSKCYLWLGNCASAESRSSAFFCI 374
            L  I+G    +   VE    + +L     FLLL+     C+LW+G  A+   ++ A    
Sbjct: 1445 LLQIKGRRHVQTRLVEP--RASALNSGDCFLLLS--PHCCFLWVGEFANVIEKAKASELA 1500

Query: 375  KQLLAKKPIDLRITLNDIKIEEIEQGKEPRT-----FWEDMG 485
              +  K+ +  R T     I+ IE+G    T     FW+ +G
Sbjct: 1501 TLIQTKRELGCRATY----IQTIEEGINTHTHAAKDFWKLLG 1538
>sp|Q8K4L3|SVIL_MOUSE Supervillin (Archvillin) (p205/p250)
          Length = 2170

 Score =  138 bits (348), Expect = 2e-32
 Identities = 82/250 (32%), Positives = 136/250 (54%), Gaps = 8/250 (3%)
 Frame = +3

Query: 3    QGISTSITEKTASALLTIDLDKDRTTQIRVKQHHESPAFCRLFGGTMVVHIG-KQQFSEN 179
            QG  ++++EK  SAL+T++LD++R  Q++V Q  E P F + F G MVVH G +++  EN
Sbjct: 1773 QGRHSTVSEKGTSALMTVELDEERGAQVQVLQGKEPPCFLQCFQGGMVVHSGRREEEEEN 1832

Query: 180  V-SKSRLFVIRGEIESEAHFVEVLCESQSLRERGVFLLLNIKRSKCYLWLGNCASAESRS 356
            V S+ RL+ +RGE+  E + +EV C   SLR R   ++LNI ++  YLW G  A   ++ 
Sbjct: 1833 VQSEWRLYCVRGEVPMEGNLLEVACHCSSLRSRTSMVVLNINKALIYLWHGCKAQGHTKE 1892

Query: 357  SAFFCIKQLLAKKPIDLRI-TLNDIKIEEIEQGKEPRTFWEDMGIIKKWKSSYIYHD--- 524
                   ++  + P++  + + +++ I E ++G EP  FW+ +G   +     +  D   
Sbjct: 1893 VGRTAANKIKEECPLEAGLHSSSNVTIHECDEGSEPLGFWDALGRRDRKAYDCMLQDPGS 1952

Query: 525  --LVPIRGWFVSGLTGVFILNEMNYSLCPDGENNIVPAFPLLQATLYKSSQPTLFLIWTP 698
                P R + +S  +G F   E  Y   P    + V + P LQ  LY + QP LFL+   
Sbjct: 1953 FNFAP-RLFILSSSSGDFSATEFVY---PAQAPSAVSSMPFLQEDLYSAPQPALFLVDNH 2008

Query: 699  VHIFIWEGWW 728
              +++W+GWW
Sbjct: 2009 HEVYLWQGWW 2018

 Score = 31.6 bits (70), Expect = 3.1
 Identities = 28/105 (26%), Positives = 46/105 (43%), Gaps = 5/105 (4%)
 Frame = +3

Query: 186  KSRLFVIRGEIESEAHFVEVLCESQSLRERGVFLLLNIKRSKCYLWLGNCASAESRSSAF 365
            K  L  I+G    +   VE    + SL     FLLL+ +   C+LW+G  ++   ++ A 
Sbjct: 1398 KLMLLQIKGRRHVQTRLVEP--RASSLNSGDCFLLLSPQY--CFLWVGEFSNVIEKAKAS 1453

Query: 366  FCIKQLLAKKPIDLRITLNDIKIEEIEQGKEPRT-----FWEDMG 485
                 +  K+ +  R T     I+ IE+G    T     FW+ +G
Sbjct: 1454 ELATLIQTKRELGCRATY----IQTIEEGINTHTHAAKDFWKLLG 1494
>sp|Q28046|ADSV_BOVIN Adseverin (Scinderin) (SC)
          Length = 715

 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 56/205 (27%), Positives = 90/205 (43%), Gaps = 10/205 (4%)
 Frame = +3

Query: 3    QGISTSITEKTASALLTIDLDKD---RTTQIRVKQHHESPAFCRLFGGTMVV----HIGK 161
            QG + +  E T SA LT+ LD+    +  QIRV Q  E      LF    ++       K
Sbjct: 441  QGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQGKEPAHLLSLFKDKPLIIYKNGTSK 500

Query: 162  QQFSENVSKSRLFVIRGEIESEAHFVEVLCESQSLRERGVFLLLNIKRSKCYLWLGNCAS 341
            ++        RLF +R  + S    +EV  ++ SL    VF+L  ++++  Y+W+G  ++
Sbjct: 501  KEGQAPAPPIRLFQVRRNLASITRIMEVDVDANSLNSNDVFVL-KLRQNNGYIWIGKGST 559

Query: 342  AESRSSAFFCIKQLLAKKPIDLRITLNDIKIEEIEQGKEPRTFWEDMGIIKKWKSSYIYH 521
             E    A +    L  K                I++GKEP  FW  +G  K +++S +  
Sbjct: 560  QEEEKGAEYVASVLKCKT-------------STIQEGKEPEEFWNSLGGKKDYQTSPLLE 606

Query: 522  DLV---PIRGWFVSGLTGVFILNEM 587
                  P R +  S  TG FI+ E+
Sbjct: 607  SQAEDHPPRLYGCSNKTGRFIIEEV 631
>sp|Q9Y6U3|ADSV_HUMAN Adseverin (Scinderin)
          Length = 715

 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 59/205 (28%), Positives = 91/205 (44%), Gaps = 10/205 (4%)
 Frame = +3

Query: 3    QGISTSITEKTASALLTIDLDKD---RTTQIRVKQHHESPAFCRLFGGTMVV----HIGK 161
            QG + +  E T SA LT+ LD+    +  QIRV Q  E      LF    ++       K
Sbjct: 441  QGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIYKNGTSK 500

Query: 162  QQFSENVSKSRLFVIRGEIESEAHFVEVLCESQSLRERGVFLLLNIKRSKCYLWLGNCAS 341
            +        +RLF +R  + S    VEV  ++ SL    VF+L  + ++  Y+W+G  AS
Sbjct: 501  KGGQAPAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDVFVL-KLPQNSGYIWVGKGAS 559

Query: 342  AESRSSAFFCIKQLLAKKPIDLRITLNDIKIEEIEQGKEPRTFWEDMGIIKKWKSSYIYH 521
             E    A +    L  K       TL       I++G+EP  FW  +G  K +++S +  
Sbjct: 560  QEEEKGAEYVASVLKCK-------TLR------IQEGEEPEEFWNSLGGKKDYQTSPLLE 606

Query: 522  DLV---PIRGWFVSGLTGVFILNEM 587
                  P R +  S  TG F++ E+
Sbjct: 607  TQAEDHPPRLYGCSNKTGRFVIEEI 631
>sp|Q60604|ADSV_MOUSE Adseverin (Scinderin) (Gelsolin-like protein)
          Length = 715

 Score = 67.8 bits (164), Expect = 4e-11
 Identities = 56/205 (27%), Positives = 88/205 (42%), Gaps = 10/205 (4%)
 Frame = +3

Query: 3    QGISTSITEKTASALLTIDLDKD---RTTQIRVKQHHESPAFCRLFGGTMVV----HIGK 161
            QG + +  E T SA LT+ LD+    +  Q+RV Q  E      LF    ++       K
Sbjct: 441  QGANATRDELTMSAFLTVQLDRSLGGQAVQVRVSQGKEPAHLLSLFKDKPLIIYKNGTSK 500

Query: 162  QQFSENVSKSRLFVIRGEIESEAHFVEVLCESQSLRERGVFLLLNIKRSKCYLWLGNCAS 341
            ++       +RLF +R  + S    VEV  ++ SL     F+L  + R+  ++W+G  AS
Sbjct: 501  KEGQAPAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDTFVL-KLPRNNGFIWIGKGAS 559

Query: 342  AESRSSAFFCIKQLLAKKPIDLRITLNDIKIEEIEQGKEPRTFWEDMGIIKKWKSSYIYH 521
             E    A +    L  K                I++GKEP  FW  +G    +++S +  
Sbjct: 560  QEEEKGAEYVADVLKCKA-------------SRIQEGKEPEEFWNSLGGRGDYQTSPLLE 606

Query: 522  DLV---PIRGWFVSGLTGVFILNEM 587
                  P R +  S  TG FI+ E+
Sbjct: 607  TRAEDHPPRLYGCSNKTGRFIIEEV 631
>sp|Q62468|VILI_MOUSE Villin-1
          Length = 827

 Score = 67.4 bits (163), Expect = 5e-11
 Identities = 54/167 (32%), Positives = 74/167 (44%), Gaps = 6/167 (3%)
 Frame = +3

Query: 3   QGISTSITEKTASALLTIDLDK---DRTTQIRVKQHHESPAFCRLFGGTMVVHIG---KQ 164
           QG   S  E  ASA   + LD+   D   QIRV    E P    +F G MVV+ G   ++
Sbjct: 447 QGSQASQDEIAASAYQAVLLDQKYNDEPVQIRVTMGKEPPHLMSIFKGRMVVYQGGTSRK 506

Query: 165 QFSENVSKSRLFVIRGEIESEAHFVEVLCESQSLRERGVFLLLNIKRSKCYLWLGNCASA 344
              E V  +RLF +RG         EV   + SL    VF+L     S CYLW G   S 
Sbjct: 507 NNLEPVPSTRLFQVRGTNADNTKAFEVTARATSLNSNDVFILKT--PSCCYLWCGKGCSG 564

Query: 345 ESRSSAFFCIKQLLAKKPIDLRITLNDIKIEEIEQGKEPRTFWEDMG 485
           + R          +AK   D   T++  + + + +G+EP  FW  +G
Sbjct: 565 DERE---------MAKMVAD---TISRTEKQVVVEGQEPANFWMALG 599
>sp|Q07171|GELS_DROME Gelsolin precursor
          Length = 798

 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 40/133 (30%), Positives = 66/133 (49%)
 Frame = +3

Query: 84  IRVKQHHESPAFCRLFGGTMVVHIGKQQFSENVSKSRLFVIRGEIESEAHFVEVLCESQS 263
           ++  Q HE   F ++F G ++       F+     ++LF IRG +ES+ H  EV  +S S
Sbjct: 540 VQTNQGHEPRHFYKIFKGKLLT-----SFTALPVTAQLFRIRGTVESDVHASEVAADSSS 594

Query: 264 LRERGVFLLLNIKRSKCYLWLGNCASAESRSSAFFCIKQLLAKKPIDLRITLNDIKIEEI 443
           L     F+L + K  K Y+W G  ASA  + +A                   +D+++E++
Sbjct: 595 LASSDAFVLHSGKSHKIYIWNGLGASAFEKQAAVDRFSDY-----------WDDVELEQV 643

Query: 444 EQGKEPRTFWEDM 482
           E+G EP  FWE++
Sbjct: 644 EEGAEPDEFWEEL 656

 Score = 30.8 bits (68), Expect = 5.4
 Identities = 21/77 (27%), Positives = 31/77 (40%), Gaps = 6/77 (7%)
 Frame = +3

Query: 315 YLWLGNCASAESRSSAFFCIKQLLAKKPIDLRITLNDIKIEEIEQGKEPRTF------WE 476
           YLW+G   S E         K     +P     + + + I  + QGKEPR F      W+
Sbjct: 717 YLWVGYGVSEEENGKLLDTAKLYFNLEPTAR--SFDTVSIIRVPQGKEPRVFKRMFPNWD 774

Query: 477 DMGIIKKWKSSYIYHDL 527
           D      W++   Y D+
Sbjct: 775 D----NYWQNQPSYEDM 787
>sp|O88398|AVIL_MOUSE Advillin (p92) (Actin-binding protein DOC6)
          Length = 819

 Score = 64.3 bits (155), Expect = 4e-10
 Identities = 62/208 (29%), Positives = 95/208 (45%), Gaps = 13/208 (6%)
 Frame = +3

Query: 3    QGISTSITEKTASALLTIDLDK--DRT-TQIRVKQHHESPAFCRLFGGTMVVHIGKQQFS 173
            QG   S  E  ASA   +++D+  DR   Q+RV    E   F  +F G +V++ G     
Sbjct: 444  QGRHASRDELAASAYRAVEVDQQFDRAPVQVRVSMGKEPRHFMAIFKGKLVIYEGGTSRK 503

Query: 174  ENVSKS---RLFVIRGEIESEAHFVEVLCESQSLRERGVFLLLNIKRSKCYLWLGNCASA 344
             N       RLF I G  +S    VEV   + SL    VFLL    +++ YLW G  +S 
Sbjct: 504  GNEEPDPPVRLFQIHGNDKSNTKAVEVSASASSLISNDVFLLRT--QAEHYLWYGKGSSG 561

Query: 345  ESRSSAFFCIKQLLAKKPIDLRITLNDIKIEEIEQGKEPRTFWEDMGIIKKWKSSYIYHD 524
            + R+         +AK+ +DL   L D   + + +G+EP  FW+ +G     K++Y    
Sbjct: 562  DERA---------MAKELVDL---LCDGNADTVAEGQEPPEFWDLLG----GKTAYANDK 605

Query: 525  L-------VPIRGWFVSGLTGVFILNEM 587
                    V +R +  S  TG F++ E+
Sbjct: 606  RLQQETLDVQVRLFECSNKTGRFLVTEV 633
>sp|Q27319|GELS_HOMAM Gelsolin, cytoplasmic (Actin-depolymerizing factor) (ADF)
          Length = 754

 Score = 63.5 bits (153), Expect = 7e-10
 Identities = 49/173 (28%), Positives = 83/173 (47%), Gaps = 12/173 (6%)
 Frame = +3

Query: 3   QGISTSITEKTASALLTIDLDKD---RTTQIRVKQHHESPAFCRLFGGTMVVHIG----- 158
           QG ++S  EK +SA+ T+ LD +   +  Q+RV Q +E   F R+F G MV+ +G     
Sbjct: 453 QGCASSQDEKASSAIHTVRLDNELCGKAVQVRVVQGYEPAHFLRIFKGRMVIFLGGKASG 512

Query: 159 ----KQQFSENVSKSRLFVIRGEIESEAHFVEVLCESQSLRERGVFLLLNIKRSKCYLWL 326
                   + +V  +RLF +RG  + +   ++    + SL    VF+L      K YLW+
Sbjct: 513 FKNVHDHDTYDVDGTRLFRVRGTCDFDTRAIQQTEVAGSLNSDDVFVLET--PGKTYLWI 570

Query: 327 GNCASAESRSSAFFCIKQLLAKKPIDLRITLNDIKIEEIEQGKEPRTFWEDMG 485
           G  AS E ++         + +K ++L     D  +  + +G+E   FW  +G
Sbjct: 571 GKGASEEEKA---------MGEKVVELVSPGRD--MVTVAEGEEDDDFWGGLG 612
>sp|P09327|VILI_HUMAN Villin-1
          Length = 827

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 51/167 (30%), Positives = 74/167 (44%), Gaps = 6/167 (3%)
 Frame = +3

Query: 3   QGISTSITEKTASALLTIDLDKD---RTTQIRVKQHHESPAFCRLFGGTMVVHIGKQQFS 173
           QG   S  E TASA   + LD+       QIRV    E P    +F G MVV+ G    +
Sbjct: 447 QGSQASQDEITASAYQAVILDQKYNGEPVQIRVPMGKEPPHLMSIFKGRMVVYQGGTSRT 506

Query: 174 ENVS---KSRLFVIRGEIESEAHFVEVLCESQSLRERGVFLLLNIKRSKCYLWLGNCASA 344
            N+     +RLF ++G   +     EV   +  L    VF+L    +S CYLW G   S 
Sbjct: 507 NNLETGPSTRLFQVQGTGANNTKAFEVPARANFLNSNDVFVLKT--QSCCYLWCGKGCSG 564

Query: 345 ESRSSAFFCIKQLLAKKPIDLRITLNDIKIEEIEQGKEPRTFWEDMG 485
           + R          +AK   D   T++  + + + +G+EP  FW  +G
Sbjct: 565 DERE---------MAKMVAD---TISRTEKQVVVEGQEPANFWMALG 599
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 105,894,308
Number of Sequences: 369166
Number of extensions: 2190003
Number of successful extensions: 4927
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4737
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4897
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9030416440
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)