Planaria EST Database


DrC_01695

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_01695
         (803 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|P24298|ALAT_HUMAN  Alanine aminotransferase (Glutamic--py...   227   3e-59
sp|P25409|ALAT_RAT  Alanine aminotransferase (Glutamic--pyru...   221   1e-57
sp|Q8QZR5|ALAT_MOUSE  Alanine aminotransferase (Glutamic--py...   221   2e-57
sp|P52894|ALA2_HORVU  Alanine aminotransferase 2 (GPT) (Glut...   169   1e-41
sp|P34106|ALA2_PANMI  Alanine aminotransferase 2 (GPT) (Glut...   166   7e-41
sp|P52892|ALAT_YEAST  Putative alanine aminotransferase (Glu...   159   6e-39
sp|P52893|ALAM_YEAST  Putative alanine aminotransferase, mit...   156   5e-38
sp|Q10334|ALAT_SCHPO  Putative alanine aminotransferase (Glu...   142   8e-34
sp|P71348|Y286_HAEIN  Probable aminotransferase HI0286             49   1e-05
sp|P63499|AAT_MYCBO  Probable aspartate aminotransferase (Tr...    46   1e-04
>sp|P24298|ALAT_HUMAN Alanine aminotransferase (Glutamic--pyruvic transaminase) (GPT)
           (Glutamic--alanine transaminase)
          Length = 496

 Score =  227 bits (578), Expect = 3e-59
 Identities = 111/213 (52%), Positives = 148/213 (69%), Gaps = 1/213 (0%)
 Frame = +1

Query: 163 LSIHNMNANIKNLEYAVRGPIVIKAQELEKRLAQGENLPFKEVIKCNIGDCHAMGQQPIT 342
           L++  MN  ++ +EYAVRGPIV +A ELE+ L QG   PF EVI+ NIGD  AMGQ+PIT
Sbjct: 21  LTLDGMNPRVRRVEYAVRGPIVQRALELEQELRQGVKKPFTEVIRANIGDAQAMGQRPIT 80

Query: 343 FLRQVVTLTAMPEFLKSKHFPQDAKNRAKRILESCGGESVGAYSQSTGVEVVRHDVAEFI 522
           FLRQV+ L   P+ L S +FP DAK RA+RIL++CGG S+GAYS S+G++++R DVA +I
Sbjct: 81  FLRQVLALCVNPDLLSSPNFPDDAKKRAERILQACGGHSLGAYSVSSGIQLIREDVARYI 140

Query: 523 SKRD-GIPSNPNDIFLSTGASEAIKVILQMMATQTHGKDKAGIMVPIPQYPLYSATNAEY 699
            +RD GIP++PN++FLSTGAS+AI  +L+++     G  + G+++PIPQYPLYSAT AE 
Sbjct: 141 ERRDGGIPADPNNVFLSTGASDAIVTVLKLLVA-GEGHTRTGVLIPIPQYPLYSATLAEL 199

Query: 700 NAYQIGYYLSEETNWGXXXXXXXXXXXXXXKHC 798
            A Q+ YYL EE  W                HC
Sbjct: 200 GAVQVDYYLDEERAWALDVAELHRALGQARDHC 232
>sp|P25409|ALAT_RAT Alanine aminotransferase (Glutamic--pyruvic transaminase) (GPT)
           (Glutamic--alanine transaminase)
          Length = 496

 Score =  221 bits (564), Expect = 1e-57
 Identities = 108/195 (55%), Positives = 146/195 (74%), Gaps = 1/195 (0%)
 Frame = +1

Query: 163 LSIHNMNANIKNLEYAVRGPIVIKAQELEKRLAQGENLPFKEVIKCNIGDCHAMGQQPIT 342
           L++  MN  ++ +EYAVRGPIV +A ELE+ L QG   PF EVI+ NIGD  AMGQ+PIT
Sbjct: 21  LTLDTMNPCVRRVEYAVRGPIVQRALELEQELRQGVKKPFTEVIRANIGDAQAMGQRPIT 80

Query: 343 FLRQVVTLTAMPEFLKSKHFPQDAKNRAKRILESCGGESVGAYSQSTGVEVVRHDVAEFI 522
           F RQV+ L   P  L S  FP+DAK RA+RIL++CGG S+GAYS S+G++ +R DVA++I
Sbjct: 81  FFRQVLALCVYPNLLSSPDFPEDAKRRAERILQACGGHSLGAYSISSGIQPIREDVAQYI 140

Query: 523 SKRD-GIPSNPNDIFLSTGASEAIKVILQMMATQTHGKDKAGIMVPIPQYPLYSATNAEY 699
            +RD GIP++PN+IFLSTGAS+AI  +L+++ +   G+ + G+++PIPQYPLYSA  AE 
Sbjct: 141 ERRDGGIPADPNNIFLSTGASDAIVTMLKLLVS-GEGRARTGVLIPIPQYPLYSAALAEL 199

Query: 700 NAYQIGYYLSEETNW 744
           +A Q+ YYL EE  W
Sbjct: 200 DAVQVDYYLDEERAW 214
>sp|Q8QZR5|ALAT_MOUSE Alanine aminotransferase (Glutamic--pyruvic transaminase) (GPT)
           (Glutamic--alanine transaminase)
          Length = 496

 Score =  221 bits (563), Expect = 2e-57
 Identities = 108/195 (55%), Positives = 145/195 (74%), Gaps = 1/195 (0%)
 Frame = +1

Query: 163 LSIHNMNANIKNLEYAVRGPIVIKAQELEKRLAQGENLPFKEVIKCNIGDCHAMGQQPIT 342
           L++  MN  ++ +EYAVRGPIV +A ELE+ L QG   PF EVI+ NIGD  AMGQ+PIT
Sbjct: 21  LTLDTMNPCVRRVEYAVRGPIVQRALELEQELRQGVKKPFTEVIRANIGDAQAMGQRPIT 80

Query: 343 FLRQVVTLTAMPEFLKSKHFPQDAKNRAKRILESCGGESVGAYSQSTGVEVVRHDVAEFI 522
           F RQV+ L   P  L S  FP+DAK RA+RIL++CGG S+GAYS S+G++ +R DVA++I
Sbjct: 81  FFRQVLALCVYPNLLSSPDFPEDAKRRAERILQACGGHSLGAYSISSGIQPIREDVAQYI 140

Query: 523 SKRD-GIPSNPNDIFLSTGASEAIKVILQMMATQTHGKDKAGIMVPIPQYPLYSATNAEY 699
            +RD GIP++PN+IFLSTGAS+AI  +L+++     G+ + G+++PIPQYPLYSA  AE 
Sbjct: 141 ERRDGGIPADPNNIFLSTGASDAIVTMLKLLVA-GEGRARTGVLIPIPQYPLYSAALAEL 199

Query: 700 NAYQIGYYLSEETNW 744
           +A Q+ YYL EE  W
Sbjct: 200 DAVQVDYYLDEERAW 214
>sp|P52894|ALA2_HORVU Alanine aminotransferase 2 (GPT) (Glutamic--pyruvic transaminase 2)
           (Glutamic--alanine transaminase 2) (ALAAT-2)
          Length = 482

 Score =  169 bits (427), Expect = 1e-41
 Identities = 87/201 (43%), Positives = 132/201 (65%), Gaps = 5/201 (2%)
 Frame = +1

Query: 160 SLSIHNMNANIKNLEYAVRGPIVIKAQELEKRL-AQGENLPFKEVIKCNIGDCHAMGQQP 336
           ++++ N+N  +   EYAVRG IVI AQ L+++L  Q  +LPF E++ CNIG+  ++GQQP
Sbjct: 4   TVAVDNLNPKVLKCEYAVRGEIVIHAQRLQEQLKTQPGSLPFDEILYCNIGNPQSLGQQP 63

Query: 337 ITFLRQVVTLTAMPEFLKSKH----FPQDAKNRAKRILESCGGESVGAYSQSTGVEVVRH 504
           +TF R+V+ L   P+ L+ +     F  D+ +RAK+IL    G + GAYS S G++ +R 
Sbjct: 64  VTFFREVLALCDHPDLLQREEIKTLFSADSISRAKQILAMIPGRATGAYSHSQGIKGLRD 123

Query: 505 DVAEFISKRDGIPSNPNDIFLSTGASEAIKVILQMMATQTHGKDKAGIMVPIPQYPLYSA 684
            +A  I+ RDG P+N +DIFL+ GAS  + +++Q++       +K GI+VPIPQYPLYSA
Sbjct: 124 AIASGIASRDGFPANADDIFLTDGASPGVHLMMQLLIR----NEKDGILVPIPQYPLYSA 179

Query: 685 TNAEYNAYQIGYYLSEETNWG 747
           + A +    + YYL+E T WG
Sbjct: 180 SIALHGGALVPYYLNESTGWG 200
>sp|P34106|ALA2_PANMI Alanine aminotransferase 2 (GPT) (Glutamic--pyruvic transaminase 2)
           (Glutamic--alanine transaminase 2) (ALAAT-2)
          Length = 482

 Score =  166 bits (420), Expect = 7e-41
 Identities = 86/201 (42%), Positives = 131/201 (65%), Gaps = 5/201 (2%)
 Frame = +1

Query: 160 SLSIHNMNANIKNLEYAVRGPIVIKAQELEKRL-AQGENLPFKEVIKCNIGDCHAMGQQP 336
           ++++ N+N  +   EYAVRG IVI AQ L+++L  Q  +LPF E++ CNIG+  ++GQQP
Sbjct: 4   TVAVENLNPKVLKCEYAVRGEIVIHAQHLQQQLQTQPGSLPFDEILYCNIGNPQSLGQQP 63

Query: 337 ITFLRQVVTLTAMPEFLKSKH----FPQDAKNRAKRILESCGGESVGAYSQSTGVEVVRH 504
           +TF R+V+ L   P  L+ +     F  DA +RAK+IL +  G + GAYS S G++ +R 
Sbjct: 64  VTFFREVLALCDHPCLLEKEETKSLFSADAISRAKQILSTIPGRATGAYSHSQGIKGLRD 123

Query: 505 DVAEFISKRDGIPSNPNDIFLSTGASEAIKVILQMMATQTHGKDKAGIMVPIPQYPLYSA 684
            +A  I+ RDG P+N +DIF++ GAS  + +++Q++       +K GI+ PIPQYPLYSA
Sbjct: 124 AIAAGIASRDGFPANADDIFVTDGASPGVHMMMQLLIR----NEKDGILCPIPQYPLYSA 179

Query: 685 TNAEYNAYQIGYYLSEETNWG 747
           + A +    + YYL E+T WG
Sbjct: 180 SIALHGGTLVPYYLDEKTGWG 200
>sp|P52892|ALAT_YEAST Putative alanine aminotransferase (Glutamic--pyruvic transaminase)
           (GPT) (Glutamic--alanine transaminase)
          Length = 507

 Score =  159 bits (403), Expect = 6e-39
 Identities = 86/200 (43%), Positives = 127/200 (63%), Gaps = 10/200 (5%)
 Frame = +1

Query: 175 NMNANIKNLEYAVRGPIVIKAQELEKRLAQG-ENLPFKEVIKCNIGDCHAMGQQPITFLR 351
           ++N  +   EYAVRG I  +A EL++ L +  E LPF ++I  NIG+   + Q+P+TF R
Sbjct: 30  DLNTGVTKAEYAVRGAIPTRADELKEELKKNPEVLPFDDIINANIGNPQQLDQKPLTFTR 89

Query: 352 QVVTLTAMPEFLKSKH--------FPQDAKNRAKRILESCGGESVGAYSQSTGVEVVRHD 507
           QV+ +   PE L+  H        F +DA  RA+R+L   GG S+GAYS S GV  +R  
Sbjct: 90  QVLAILEYPEILRVGHNELASLNLFSRDALERAERLLNDIGG-SIGAYSHSQGVPGIRQT 148

Query: 508 VAEFISKRDG-IPSNPNDIFLSTGASEAIKVILQMMATQTHGKDKAGIMVPIPQYPLYSA 684
           VA+FI++RDG  P+ P DI+L+TGAS A   +L ++   +    + G+++PIPQYPLY+A
Sbjct: 149 VADFITRRDGGEPATPEDIYLTTGASSAATSLLSLLCKDS----QTGLLIPIPQYPLYTA 204

Query: 685 TNAEYNAYQIGYYLSEETNW 744
           + + +NA  + YYL EE+NW
Sbjct: 205 SASLFNAQVLPYYLDEESNW 224
>sp|P52893|ALAM_YEAST Putative alanine aminotransferase, mitochondrial precursor
           (Glutamic--pyruvic transaminase) (GPT)
           (Glutamic--alanine transaminase)
          Length = 592

 Score =  156 bits (395), Expect = 5e-38
 Identities = 90/204 (44%), Positives = 128/204 (62%), Gaps = 10/204 (4%)
 Frame = +1

Query: 163 LSIHNMNANIKNLEYAVRGPIVIKAQELEKRLAQG-ENLPFKEVIKCNIGDCHAMGQQPI 339
           L++ ++N N+   +YAVRG I ++A+EL+ +L +  ++LPF  +I  NIG+   + Q+P+
Sbjct: 111 LTLEDVNENVLKAKYAVRGAIPMRAEELKAQLEKDPQSLPFDRIINANIGNPQQLQQKPL 170

Query: 340 TFLRQVVTLTAMPEFLK--------SKHFPQDAKNRAKRILESCGGESVGAYSQSTGVEV 495
           T+ RQV++L   PE L         SK F  DA  RAK ++E  GG SVGAYS S GVE 
Sbjct: 171 TYYRQVLSLLQYPELLNQNEQQLVDSKLFKLDAIKRAKSLMEDIGG-SVGAYSSSQGVEG 229

Query: 496 VRHDVAEFISKRD-GIPSNPNDIFLSTGASEAIKVILQMMATQTHGKDKAGIMVPIPQYP 672
           +R  VAEFI+KRD G  S P DIFL+ GAS A+  +L +         + G+++PIPQYP
Sbjct: 230 IRKSVAEFITKRDEGEISYPEDIFLTAGASAAVNYLLSIFCRGP----ETGVLIPIPQYP 285

Query: 673 LYSATNAEYNAYQIGYYLSEETNW 744
           LY+AT A  N+  + YYL E + W
Sbjct: 286 LYTATLALNNSQALPYYLDENSGW 309
>sp|Q10334|ALAT_SCHPO Putative alanine aminotransferase (Glutamic--pyruvic transaminase)
           (GPT) (Glutamic--alanine transaminase)
          Length = 505

 Score =  142 bits (359), Expect = 8e-34
 Identities = 79/200 (39%), Positives = 115/200 (57%), Gaps = 8/200 (4%)
 Frame = +1

Query: 169 IHNMNANIKNLEYAVRGPIVIKAQELEKRLAQG-ENLPFKEVIKCNIGDCHAMGQQPITF 345
           ++++N  +    YAVRG + I A E++  L +   + PF E++  NIG+   MGQ PITF
Sbjct: 30  LNSLNQQVFKANYAVRGALAILADEIQDDLLENPSSYPFSEIVYANIGNPQQMGQSPITF 89

Query: 346 LRQVVTLTAMPEFLKSKH-------FPQDAKNRAKRILESCGGESVGAYSQSTGVEVVRH 504
           +RQV++L   P  L           FP D   R+K +L+  G  S+GAYS S G+ +VR 
Sbjct: 90  VRQVLSLCQYPTLLDHAEEKWFQNLFPTDVVQRSKMLLKESG--SLGAYSASQGIPLVRR 147

Query: 505 DVAEFISKRDGIPSNPNDIFLSTGASEAIKVILQMMATQTHGKDKAGIMVPIPQYPLYSA 684
            VA+FI  RDG    P+DI+L++GAS A ++I+ ++      +   G+MVP PQYPLY A
Sbjct: 148 HVADFIRARDGFDCEPSDIYLTSGASHAARLIMTLII----ARPTDGVMVPAPQYPLYGA 203

Query: 685 TNAEYNAYQIGYYLSEETNW 744
                +   + Y LSEE NW
Sbjct: 204 QIDLMSGSMVSYSLSEENNW 223
>sp|P71348|Y286_HAEIN Probable aminotransferase HI0286
          Length = 404

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 40/185 (21%), Positives = 74/185 (40%)
 Frame = +1

Query: 190 IKNLEYAVRGPIVIKAQELEKRLAQGENLPFKEVIKCNIGDCHAMGQQPITFLRQVVTLT 369
           ++++ Y +RGP+  +A  LE+           +++K NIG+    G +            
Sbjct: 10  LEHVCYDIRGPVHKEALRLEEE--------GNKILKLNIGNPAPFGFEA----------- 50

Query: 370 AMPEFLKSKHFPQDAKNRAKRILESCGGESVGAYSQSTGVEVVRHDVAEFISKRDGIPSN 549
                      P +      R L S  G     Y  S G+   R  + ++   +  + + 
Sbjct: 51  -----------PDEILVDVLRNLPSAQG-----YCDSKGLYSARKAIVQYYQSKGILGAT 94

Query: 550 PNDIFLSTGASEAIKVILQMMATQTHGKDKAGIMVPIPQYPLYSATNAEYNAYQIGYYLS 729
            ND+++  G SE I + +Q +       D   ++VP+P YPL++A         + Y   
Sbjct: 95  VNDVYIGNGVSELITMAMQALLN-----DGDEVLVPMPDYPLWTAAVTLSGGKAVHYLCD 149

Query: 730 EETNW 744
           E+ NW
Sbjct: 150 EDANW 154
>sp|P63499|AAT_MYCBO Probable aspartate aminotransferase (Transaminase A) (ASPAT)
 sp|P63498|AAT_MYCTU Probable aspartate aminotransferase (Transaminase A) (ASPAT)
          Length = 429

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 46/190 (24%), Positives = 77/190 (40%), Gaps = 2/190 (1%)
 Frame = +1

Query: 181 NANIKNLEYAVRGPIVIKAQELEKRLAQGENLPFKEVIKCNIGDCHAMG-QQPITFLRQV 357
           +A ++++ Y +RGP+   A  LE   A+G       ++K NIG+    G + P   +R +
Sbjct: 31  SAKLQDVLYEIRGPVHQHAARLE---AEGHR-----ILKLNIGNPAPFGFEAPDVIMRDI 82

Query: 358 VTLTAMPEFLKSKHFPQDAKNRAKRILESCGGESVGAYSQSTGVEVVRHDVAEFISKRDG 537
           +   A+P                              YS S G+   R  V        G
Sbjct: 83  IQ--ALPY--------------------------AQGYSDSQGILSARRAVVTRYELVPG 114

Query: 538 IPS-NPNDIFLSTGASEAIKVILQMMATQTHGKDKAGIMVPIPQYPLYSATNAEYNAYQI 714
            P  + +D++L  G SE I + LQ  A   +G     +++P P YPL++A+ +      +
Sbjct: 115 FPRFDVDDVYLGNGVSELITMTLQ--ALLDNGDQ---VLIPSPDYPLWTASTSLAGGTPV 169

Query: 715 GYYLSEETNW 744
            Y   E   W
Sbjct: 170 HYLCDETQGW 179
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 80,798,669
Number of Sequences: 369166
Number of extensions: 1556915
Number of successful extensions: 3834
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3709
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3811
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7618580670
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)