Planaria EST Database


DrC_01689

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_01689
         (823 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|P50580|PA2G4_MOUSE  Proliferation-associated protein 2G4 ...   213   5e-55
sp|Q9UQ80|PA2G4_HUMAN  Proliferation-associated protein 2G4 ...   210   4e-54
sp|Q09184|CDB4_SCHPO  Curved DNA-binding protein (42 kDa pro...   159   9e-39
sp|O28438|AMPM_ARCFU  Methionine aminopeptidase (MAP) (Pepti...    70   9e-12
sp|Q9UYT4|AMPM_PYRAB  Methionine aminopeptidase (MAP) (Pepti...    60   7e-09
sp|O58362|AMPM_PYRHO  Methionine aminopeptidase (MAP) (Pepti...    56   1e-07
sp|O08663|AMPM2_MOUSE  Methionine aminopeptidase 2 (MetAP 2)...    52   2e-06
sp|P50579|AMPM2_HUMAN  Methionine aminopeptidase 2 (MetAP 2)...    52   3e-06
sp|P56218|AMPM_PYRFU  Methionine aminopeptidase (MAP) (Pepti...    52   3e-06
sp|P22624|AMPM_METFE  Probable methionine aminopeptidase (MA...    51   3e-06
>sp|P50580|PA2G4_MOUSE Proliferation-associated protein 2G4 (Proliferation-associated
           protein 1) (Protein p38-2G4)
          Length = 394

 Score =  213 bits (542), Expect = 5e-55
 Identities = 110/267 (41%), Positives = 167/267 (62%), Gaps = 3/267 (1%)
 Frame = +1

Query: 25  EAELEVNNLEDETIVNKYKMAADIVQRILKELITKCQPGANLLELCTYGDQXXXXXXXXX 204
           E E +   + ++ +V KYKM  DI  R+L+ L+     G ++L LC  GD          
Sbjct: 4   EDEQQEQTIAEDLVVTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKI 63

Query: 205 XXXXXXXXXGCAYPTSISKNNIVANFCPEQSNETF--ENGDLVKIDLGCYIDGYAAVVGH 378
                    G A+PTSIS NN V +F P +S++ +  + GDLVKIDLG ++DG+ A V H
Sbjct: 64  FKKEKEMKKGIAFPTSISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAH 123

Query: 379 TFVIGASKDNKVTGRKADVILAAHNCVEAALRLFKPGKDSKGVTEPLIHVAGDYNCKVLE 558
           TFVIG ++  +VTGRKADVI AAH C EAALRL KPG  +  VTE    VA  +NC  +E
Sbjct: 124 TFVIGVAQGTQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIE 183

Query: 559 NCMANGMEKNIFENDKTFMINPSDDLKKS-EKVDFDVNQVWTIDVVVTTGDAKVKEREVK 735
             +++ +++++ + +KT + NP+D  KK  EK +F+V++V+ +DV+V++G+ K K+   +
Sbjct: 184 GMLSHQLKQHVIDGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDAGQR 243

Query: 736 STVYRRILADKKYQLKLKASRQIYSDV 816
           +T+Y+R    K+Y LK+K SR  +S+V
Sbjct: 244 TTIYKRD-PSKQYGLKMKTSRAFFSEV 269
>sp|Q9UQ80|PA2G4_HUMAN Proliferation-associated protein 2G4 (Cell cycle protein p38-2G4
           homolog) (hG4-1)
          Length = 394

 Score =  210 bits (534), Expect = 4e-54
 Identities = 108/267 (40%), Positives = 166/267 (62%), Gaps = 3/267 (1%)
 Frame = +1

Query: 25  EAELEVNNLEDETIVNKYKMAADIVQRILKELITKCQPGANLLELCTYGDQXXXXXXXXX 204
           E E +   + ++ +V KYKM  DI  R+L+ L+     G ++L LC  GD          
Sbjct: 4   EDEQQEQTIAEDLVVTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKI 63

Query: 205 XXXXXXXXXGCAYPTSISKNNIVANFCPEQSNETF--ENGDLVKIDLGCYIDGYAAVVGH 378
                    G A+PTSIS NN V +F P +S++ +  + GDLVKIDLG ++DG+ A V H
Sbjct: 64  FKKEKEMKKGIAFPTSISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAH 123

Query: 379 TFVIGASKDNKVTGRKADVILAAHNCVEAALRLFKPGKDSKGVTEPLIHVAGDYNCKVLE 558
           TFV+  ++  +VTGRKADVI AAH C EAALRL KPG  +  VTE    VA  +NC  +E
Sbjct: 124 TFVVDVAQGTQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIE 183

Query: 559 NCMANGMEKNIFENDKTFMINPSDDLKKS-EKVDFDVNQVWTIDVVVTTGDAKVKEREVK 735
             +++ +++++ + +KT + NP+D  KK  EK +F+V++V+ +DV+V++G+ K K+   +
Sbjct: 184 GMLSHQLKQHVIDGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDAGQR 243

Query: 736 STVYRRILADKKYQLKLKASRQIYSDV 816
           +T+Y+R    K+Y LK+K SR  +S+V
Sbjct: 244 TTIYKRD-PSKQYGLKMKTSRAFFSEV 269
>sp|Q09184|CDB4_SCHPO Curved DNA-binding protein (42 kDa protein)
          Length = 381

 Score =  159 bits (402), Expect = 9e-39
 Identities = 91/276 (32%), Positives = 159/276 (57%), Gaps = 6/276 (2%)
 Frame = +1

Query: 7   TMSSDSEAELEVNNLEDETIVNKYKMAADIVQRILKELITKCQPGANLLELCTYGDQXXX 186
           T  + SE  ++ +    ET VNKYK+A ++ Q ++K+++  CQPGA + ++C  GD+   
Sbjct: 3   TKEATSETAVDYSLSNPET-VNKYKIAGEVSQNVIKKVVELCQPGAKIYDICVRGDELLN 61

Query: 187 XXXXXXXXXXXXXXXGCAYPTSISKNNIVANFCPEQS----NETFENGDLVKIDLGCYID 354
                          G A+PT++S N++ A+  P +S    N   ++GD+VKI LG +ID
Sbjct: 62  EAIKKVYRTKDAYK-GIAFPTAVSPNDMAAHLSPLKSDPEANLALKSGDVVKILLGAHID 120

Query: 355 GYAAVVGHTFVIGASKDNKVTGRKADVILAAHNCVEAALRLFKPGKDSKGVTEPLIHVAG 534
           G+A++V  T V+    +  VTG  ADVI AA   ++AA R  KPG  +  VT+ +  +A 
Sbjct: 121 GFASLVATTTVVS---EEPVTGPAADVIAAASAALKAAQRTIKPGNTNWQVTDIVDKIAT 177

Query: 535 DYNCKVLENCMANGMEKNIFENDKTFMINPSDDLK-KSEKVDFDVNQVWTIDVVVTTG-D 708
            Y CK +   +++  E+ + +  K  ++NPSD  + + +   F+  +V+ +D++V+T   
Sbjct: 178 SYGCKPVAGMLSHQQEREVIDGKKQVILNPSDSQRSEMDTFTFEEGEVYGVDILVSTSPS 237

Query: 709 AKVKEREVKSTVYRRILADKKYQLKLKASRQIYSDV 816
            KVK  ++ + +Y++   D  Y LKL+ASR++YS++
Sbjct: 238 GKVKRSDIATRIYKK--TDTTYMLKLQASRKVYSEI 271
>sp|O28438|AMPM_ARCFU Methionine aminopeptidase (MAP) (Peptidase M)
          Length = 291

 Score = 69.7 bits (169), Expect = 9e-12
 Identities = 66/259 (25%), Positives = 117/259 (45%), Gaps = 5/259 (1%)
 Frame = +1

Query: 55  DETIVNKYKMAADIVQRILKELITKCQPGANLLELCTYGDQXXXXXXXXXXXXXXXXXXG 234
           D+ +  K   A  I+++ + E   K  PG  +LE+  + +                    
Sbjct: 2   DDEVREKLIEAGKILKQAVNEAAEKIAPGVKILEVAEFVENRIIELGAKP---------- 51

Query: 235 CAYPTSISKNNIVANFCPEQSNE-TFENGDLVKIDLGCYIDGYAAVVGHTFVIGASKDNK 411
            A+P +IS N+  A+F P++++E TF+ GD+VK+D+G +IDGY A +  T  +G   DN 
Sbjct: 52  -AFPANISINSDAAHFTPKKNDERTFKEGDVVKLDVGAHIDGYIADMAVTVDLG---DN- 106

Query: 412 VTGRKADVILAAHNCVEAALRLFKPGKDSKGVTEPLIHVAGDYNCKVLENCMANGMEKNI 591
                 +++ AA   +EAA+ + + G     + + +     +Y  K + N   +G+   +
Sbjct: 107 -----TELVKAAKEALEAAMEVVRAGVSVSEIGKAIEDAITNYGFKPIVNLTGHGLLPYL 161

Query: 592 FENDKTFMINPSDDLKKSEK-VDFDVNQVWTIDVVVTTGDAKVKER---EVKSTVYRRIL 759
                     PS     +EK V  +   V  I+   T G  KV ER   E+ S +  R  
Sbjct: 162 NH------APPSIYNYATEKGVTLEEGMVVAIEPFATNGVGKVGERGECEIYSLLNPR-- 213

Query: 760 ADKKYQLKLKASRQIYSDV 816
                 +++K +R+I  +V
Sbjct: 214 -----PVRMKMAREILKEV 227
>sp|Q9UYT4|AMPM_PYRAB Methionine aminopeptidase (MAP) (Peptidase M)
          Length = 295

 Score = 60.1 bits (144), Expect = 7e-09
 Identities = 54/222 (24%), Positives = 96/222 (43%), Gaps = 3/222 (1%)
 Frame = +1

Query: 67  VNKYKMAADIVQRILKELITKCQPGANLLELCTYGDQXXXXXXXXXXXXXXXXXXGCAYP 246
           V+K   A  I +++ +E +   +PG +LLEL    +                     A+P
Sbjct: 3   VDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIEGRIIELGAKP-----------AFP 51

Query: 247 TSISKNNIVANFCPEQSNET-FENGDLVKIDLGCYIDGYAAVVGHTFVIGASKDNKVTGR 423
            ++S N I A++ P + +ET  + GD +KID+G +IDGY A    T  +G  +D      
Sbjct: 52  VNLSLNEIAAHYTPYKGDETTLKEGDYLKIDIGVHIDGYIADTAVTVRVGMEED------ 105

Query: 424 KADVILAAHNCVEAALRLFKPGKDSKGVTEPLIHVAGDYNCKVLENCMANGMEKNIFEND 603
             D++ AA   +E+A+ + + G + K +   +           + N   + +E+      
Sbjct: 106 --DLMEAAREALESAISVARAGVEIKELGRAIEDEIRKRGFNPIVNLSGHKIERYKLHAG 163

Query: 604 KTF--MINPSDDLKKSEKVDFDVNQVWTIDVVVTTGDAKVKE 723
            +   +  P D+ K  E        V+ I+   TTG  +V E
Sbjct: 164 ISIPNIYRPHDNYKLRE------GDVFAIEPFATTGAGQVIE 199
>sp|O58362|AMPM_PYRHO Methionine aminopeptidase (MAP) (Peptidase M)
          Length = 295

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 39/146 (26%), Positives = 70/146 (47%), Gaps = 1/146 (0%)
 Frame = +1

Query: 67  VNKYKMAADIVQRILKELITKCQPGANLLELCTYGDQXXXXXXXXXXXXXXXXXXGCAYP 246
           V+K   A  I +++ +E +   +PG +LLEL    +                     A+P
Sbjct: 3   VDKLIEAGKIAKKVREEAVKLAKPGVSLLELAEKIESRIVELGGKP-----------AFP 51

Query: 247 TSISKNNIVANFCPEQSNET-FENGDLVKIDLGCYIDGYAAVVGHTFVIGASKDNKVTGR 423
            ++S N + A++ P + ++T  + GD +KIDLG +IDGY A    T  +G   D      
Sbjct: 52  ANLSLNEVAAHYTPYKGDQTVLKEGDYLKIDLGVHIDGYIADTAVTVRVGMDFD------ 105

Query: 424 KADVILAAHNCVEAALRLFKPGKDSK 501
             +++ AA   +E+A+ + + G + K
Sbjct: 106 --ELMEAAKEALESAISVARAGVEVK 129
>sp|O08663|AMPM2_MOUSE Methionine aminopeptidase 2 (MetAP 2) (Peptidase M 2) (Initiation
           factor 2-associated 67 kDa glycoprotein) (p67) (p67eIF2)
          Length = 478

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 52/225 (23%), Positives = 88/225 (39%), Gaps = 3/225 (1%)
 Frame = +1

Query: 58  ETIVNKYKMAADIVQRILKELITKCQPGANLLELCTYGDQXXXXXXXXXXXXXXXXXXGC 237
           E I N ++ AA+  +++ K +++  +PG  ++E+C                       G 
Sbjct: 163 EEIWNDFREAAEAHRQVRKYVMSWIKPGMTMIEIC-----EKLEDCSRKLIKENGLNAGL 217

Query: 238 AYPTSISKNNIVANFCPEQSNET-FENGDLVKIDLGCYIDGYAAVVGHTFVIGASKDNKV 414
           A+PT  S NN  A++ P   + T  +  D+ KID G +I G       T       D  +
Sbjct: 218 AFPTGCSLNNCAAHYTPNAGDTTVLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDILL 277

Query: 415 TGRKADVILAAHNCVEAALRLFKPGKDSKGVTEPL-IHVAG-DYNCKVLENCMANGMEKN 588
           T  K D       C    +RL   G+  + V E   + + G  Y  K + N   + +   
Sbjct: 278 TAVK-DATNTGIKCAGIDVRLCDVGEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGPY 336

Query: 589 IFENDKTFMINPSDDLKKSEKVDFDVNQVWTIDVVVTTGDAKVKE 723
                KT  I     +K  E    +  +V+ I+   +TG   V +
Sbjct: 337 RIHAGKTVPI-----VKGGEATRMEEGEVYAIETFGSTGKGVVHD 376
>sp|P50579|AMPM2_HUMAN Methionine aminopeptidase 2 (MetAP 2) (Peptidase M 2) (Initiation
           factor 2-associated 67 kDa glycoprotein) (p67) (p67eIF2)
          Length = 478

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 51/225 (22%), Positives = 88/225 (39%), Gaps = 3/225 (1%)
 Frame = +1

Query: 58  ETIVNKYKMAADIVQRILKELITKCQPGANLLELCTYGDQXXXXXXXXXXXXXXXXXXGC 237
           E I N ++ AA+  +++ K +++  +PG  ++E+C                       G 
Sbjct: 163 EEIWNDFREAAEAHRQVRKYVMSWIKPGMTMIEIC-----EKLEDCSRKLIKENGLNAGL 217

Query: 238 AYPTSISKNNIVANFCPEQSNET-FENGDLVKIDLGCYIDGYAAVVGHTFVIGASKDNKV 414
           A+PT  S NN  A++ P   + T  +  D+ KID G +I G       T       D  +
Sbjct: 218 AFPTGCSLNNCAAHYTPNAGDTTVLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLL 277

Query: 415 TGRKADVILAAHNCVEAALRLFKPGKDSKGVTEPL-IHVAG-DYNCKVLENCMANGMEKN 588
              K D       C    +RL   G+  + V E   + + G  Y  K + N   + + + 
Sbjct: 278 KAVK-DATNTGIKCAGIDVRLCDVGEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQY 336

Query: 589 IFENDKTFMINPSDDLKKSEKVDFDVNQVWTIDVVVTTGDAKVKE 723
                KT  I     +K  E    +  +V+ I+   +TG   V +
Sbjct: 337 RIHAGKTVPI-----VKGGEATRMEEGEVYAIETFGSTGKGVVHD 376
>sp|P56218|AMPM_PYRFU Methionine aminopeptidase (MAP) (Peptidase M)
          Length = 295

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 40/160 (25%), Positives = 76/160 (47%), Gaps = 6/160 (3%)
 Frame = +1

Query: 73  KYKMAADIVQRILKELITKCQPGANLLELCTYGDQXXXXXXXXXXXXXXXXXXGCAYPTS 252
           K   A +I +++ ++ I   +PG  LLEL    ++                    A+P +
Sbjct: 5   KLMKAGEIAKKVREKAIKLARPGMLLLELAESIEKMIMELGGKP-----------AFPVN 53

Query: 253 ISKNNIVANFCPEQSNET-FENGDLVKIDLGCYIDGYAAVVGHTFVIGASKDNKVTGRKA 429
           +S N I A++ P + + T  + GD +KID+G +IDG+ A    T  +G  +D  +   K 
Sbjct: 54  LSINEIAAHYTPYKGDTTVLKEGDYLKIDVGVHIDGFIADTAVTVRVGMEEDELMEAAK- 112

Query: 430 DVILAAHNCVEAALRLFKPGKD-----SKGVTEPLIHVAG 534
           + + AA +   A + + + GK       K   +P+++++G
Sbjct: 113 EALNAAISVARAGVEIKELGKAIENEIRKRGFKPIVNLSG 152
>sp|P22624|AMPM_METFE Probable methionine aminopeptidase (MAP) (Peptidase M)
          Length = 188

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 37/179 (20%), Positives = 80/179 (44%), Gaps = 6/179 (3%)
 Frame = +1

Query: 67  VNKYKMAADIVQRILKELITKCQPGANLLELCTYGDQXXXXXXXXXXXXXXXXXXGCAYP 246
           + K+K A  I  ++ K+ I   +    +L+L  + +                     A+P
Sbjct: 1   MEKFKKAGKIASKVRKKAIKAVKGEMKILDLAEFIENEIEKMGAKP-----------AFP 49

Query: 247 TSISKNNIVANFCPEQSNET-FENGDLVKIDLGCYIDGYAAVVGHTFVIGASKD-----N 408
            +IS N I A++ P  +++     GDLVKID+G ++DG+      T ++   +D     +
Sbjct: 50  CNISVNEITAHYSPPCNDDRKILPGDLVKIDIGVHVDGFIGDTATTVLVEGYEDLKNYND 109

Query: 409 KVTGRKADVILAAHNCVEAALRLFKPGKDSKGVTEPLIHVAGDYNCKVLENCMANGMEK 585
           ++  +   +I AA + +E A+   + G +   + E + +    +  K + N   + +++
Sbjct: 110 ELAEKNKKMIEAAESALENAINTIRDGVEIGKIGEVIENTINKFGFKPISNLTGHTIDR 168
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.316    0.133    0.383 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 72,666,256
Number of Sequences: 369166
Number of extensions: 1274827
Number of successful extensions: 3896
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3764
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3872
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7907893860
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)