Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_01674 (851 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P45018|HRPA_HAEIN ATP-dependent helicase hrpA homolog 124 3e-28 sp|P43329|HRPA_ECOLI ATP-dependent helicase hrpA 119 1e-26 sp|Q09530|MOG5_CAEEL Probable pre-mRNA splicing factor ATP-... 114 3e-25 sp|O35286|DHX15_MOUSE Putative pre-mRNA splicing factor RNA... 112 1e-24 sp|O43143|DHX15_HUMAN Putative pre-mRNA splicing factor RNA... 112 1e-24 sp|Q38953|DHX8_ARATH Putative pre-mRNA splicing factor ATP-... 111 3e-24 sp|Q10752|CDC28_SCHPO Putative ATP-dependent RNA helicase c... 111 3e-24 sp|Q14562|DHX8_HUMAN ATP-dependent helicase DHX8 (RNA helic... 110 4e-24 sp|O42643|DHX8_SCHPO Putative pre-mRNA splicing factor ATP-... 107 3e-23 sp|Q9H6R0|DHX33_HUMAN Putative ATP-dependent helicase DHX33... 107 4e-23
>sp|P45018|HRPA_HAEIN ATP-dependent helicase hrpA homolog Length = 1304 Score = 124 bits (312), Expect = 3e-28 Identities = 87/294 (29%), Positives = 145/294 (49%), Gaps = 11/294 (3%) Frame = +2 Query: 2 VIYRPLTSENYLANIKVVVNEI--VGKYKKGHILIFLQSEEKVLKCMKQLR--NINSTKL 169 V YRP+ E+ ++ ++N + + +G ILIF+ E ++ + L+ N+ T++ Sbjct: 265 VRYRPVVEEDDQDQLQGILNAVDELQAEGRGDILIFMNGEREIRDTAEALQKQNLKHTEI 324 Query: 170 LPFFASMDEEEKDRVFFEYGNRRKIIIATNLAETSLTIPGVDFVIDSGLVKRVRFDHKTG 349 LP FA + +E++++F G R I++ATN+AETSLT+P + +VID G + R+ ++T Sbjct: 325 LPLFARLSAQEQNKIFHPSGLNR-IVLATNVAETSLTVPSIKYVIDPGTARISRYSYRTK 383 Query: 350 VEKWMTKFISVAEADQXXXXXXXXXXXICYRLYPEKCIKSDQNDLLDEIRDLNLQNGDEN 529 V++ + IS A A+Q IC RLY E+ D N + Sbjct: 384 VQRLPIEPISQASANQRKGRCGRVSEGICIRLYSEE--------------DFNSR----- 424 Query: 530 ATIDESNKIFSKEGPKKFPKFPDPEIKTVNLNSMTLVLKSMKWDNVFDFPFIVVPEIDKI 709 P+F DPEI NL S+ L + ++ D++ FPF+ P+ I Sbjct: 425 ------------------PEFTDPEILRTNLASVILQMTALGLDDIEAFPFVDAPDERHI 466 Query: 710 ESALKELEDLSLL-------NEQRELTKIGEIASCLSLEPRLAKVATIASELPC 850 + +K LE+L E+R LT++G + L ++PRLAK+ A C Sbjct: 467 QDGVKLLEELGAFETVQTKSGEKRLLTRVGRQLAQLPVDPRLAKMILSAVNFGC 520
>sp|P43329|HRPA_ECOLI ATP-dependent helicase hrpA Length = 1300 Score = 119 bits (297), Expect = 1e-26 Identities = 88/296 (29%), Positives = 140/296 (47%), Gaps = 13/296 (4%) Frame = +2 Query: 2 VIYRPLTSE------NYLANIKVVVNEIVGKYKKGHILIFLQSEEKVLKCMKQLRNIN-- 157 V YRP+ E + L I V+E+ + G ILIF+ E ++ L +N Sbjct: 258 VRYRPIVEEADDTERDQLQAIFDAVDEL-SQESHGDILIFMSGEREIRDTADALNKLNLR 316 Query: 158 STKLLPFFASMDEEEKDRVFFEYGNRRKIIIATNLAETSLTIPGVDFVIDSGLVKRVRFD 337 T++LP +A + E++RVF + RR I++ATN+AETSLT+PG+ +VID G + R+ Sbjct: 317 HTEILPLYARLSNSEQNRVFQSHSGRR-IVLATNVAETSLTVPGIKYVIDPGTARISRYS 375 Query: 338 HKTGVEKWMTKFISVAEADQXXXXXXXXXXXICYRLYPEKCIKSDQNDLLDEIRDLNLQN 517 ++T V++ + IS A A+Q IC RLY E +D L Sbjct: 376 YRTKVQRLPIEPISQASANQRKGRCGRVSEGICIRLYSE-------DDFLSR-------- 420 Query: 518 GDENATIDESNKIFSKEGPKKFPKFPDPEIKTVNLNSMTLVLKSMKWDNVFDFPFIVVPE 697 P+F DPEI NL S+ L + ++ ++ FPF+ P+ Sbjct: 421 ----------------------PEFTDPEILRTNLASVILQMTALGLGDIAAFPFVEAPD 458 Query: 698 IDKIESALKELEDLSLLNEQRE-----LTKIGEIASCLSLEPRLAKVATIASELPC 850 I+ ++ LE+L + + LT +G S L ++PRLA++ A + C Sbjct: 459 KRNIQDGVRLLEELGAITTDEQASAYKLTPLGRQLSQLPVDPRLARMVLEAQKHGC 514
>sp|Q09530|MOG5_CAEEL Probable pre-mRNA splicing factor ATP-dependent RNA helicase mog-5 (Sex determination protein mog-5) (Masculinization of germ line protein 5) Length = 1200 Score = 114 bits (286), Expect = 3e-25 Identities = 83/292 (28%), Positives = 136/292 (46%), Gaps = 9/292 (3%) Frame = +2 Query: 2 VIYRPLTSENYLANIKVVVNEIVGKYKKGHILIFLQSEEKV-------LKCMKQLR-NIN 157 ++Y +YL + V +I G +L+FL +E++ + MK + ++ Sbjct: 721 ILYTREPESDYLEAAHITVMQIHLTEPPGDVLVFLTGQEEIDTSCEVLYERMKSMGPDVP 780 Query: 158 STKLLPFFASMDEEEKDRVFFEY-GNRRKIIIATNLAETSLTIPGVDFVIDSGLVKRVRF 334 +LP + ++ E + R+F +RK++IATN+AETSLTI G+ +V+D G VK+ + Sbjct: 781 ELIILPVYGALPSEMQTRIFDPAPAGKRKVVIATNIAETSLTIDGIFYVVDPGFVKQKIY 840 Query: 335 DHKTGVEKWMTKFISVAEADQXXXXXXXXXXXICYRLYPEKCIKSDQNDLLDEIRDLNLQ 514 + K+G++ + IS A A Q CYRLY E+ + + Sbjct: 841 NPKSGMDSLVVTPISQAAAKQRSGRAGRTGPGKCYRLYTERAFRDEMLPT---------- 890 Query: 515 NGDENATIDESNKIFSKEGPKKFPKFPDPEIKTVNLNSMTLVLKSMKWDNVFDFPFIVVP 694 P PEI+ NL S L LK+M +N+ DF F+ P Sbjct: 891 --------------------------PVPEIQRTNLASTLLQLKAMGINNLIDFDFMDAP 924 Query: 695 EIDKIESALKELEDLSLLNEQRELTKIGEIASCLSLEPRLAKVATIASELPC 850 +D + +AL L LS L+ LTK+G + LEP L+K+ ++ +L C Sbjct: 925 PLDSMITALNTLHTLSALDGDGLLTKLGRRMAEFPLEPSLSKLLIMSVDLGC 976
>sp|O35286|DHX15_MOUSE Putative pre-mRNA splicing factor RNA helicase (DEAH box protein 15) Length = 795 Score = 112 bits (280), Expect = 1e-24 Identities = 79/299 (26%), Positives = 141/299 (47%), Gaps = 16/299 (5%) Frame = +2 Query: 2 VIYRPLTSENYL-ANIKVVVNEIVGKYKKGHILIFLQSEEKVLKCMKQLRN--------I 154 + Y P +YL A I+ V+ + + ++G +L+FL +E++ + K+++ + Sbjct: 321 IFYTPEPERDYLEAAIRTVIQIHMCEEEEGDLLLFLTGQEEIDEACKRIKREVDDLGPEV 380 Query: 155 NSTKLLPFFASMDEEEKDRVFFEYGNR-------RKIIIATNLAETSLTIPGVDFVIDSG 313 K++P ++++ +++ R+F + RK++++TN+AETSLTI GV FVID G Sbjct: 381 GDIKIIPLYSTLPPQQQQRIFEPPPPKKQNGAIGRKVVVSTNIAETSLTIDGVVFVIDPG 440 Query: 314 LVKRVRFDHKTGVEKWMTKFISVAEADQXXXXXXXXXXXICYRLYPEKCIKSDQNDLLDE 493 K+ ++ + VE + IS A A Q C+RLY EK K++ D Sbjct: 441 FAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGRTRPGKCFRLYTEKAYKTEMQD---- 496 Query: 494 IRDLNLQNGDENATIDESNKIFSKEGPKKFPKFPDPEIKTVNLNSMTLVLKSMKWDNVFD 673 PEI NL S+ L LK + D++ Sbjct: 497 --------------------------------NTYPEILRSNLGSVVLQLKKLGIDDLVH 524 Query: 674 FPFIVVPEIDKIESALKELEDLSLLNEQRELTKIGEIASCLSLEPRLAKVATIASELPC 850 F F+ P + + AL+ L L+ LN+ +LT++G + + L+P+LAK+ + + C Sbjct: 525 FDFMDPPAPETLMRALELLNYLAALNDDGDLTELGSMMAEFPLDPQLAKMVIASCDYNC 583
>sp|O43143|DHX15_HUMAN Putative pre-mRNA splicing factor RNA helicase (DEAH box protein 15) (ATP-dependent RNA helicase #46) Length = 795 Score = 112 bits (280), Expect = 1e-24 Identities = 79/299 (26%), Positives = 141/299 (47%), Gaps = 16/299 (5%) Frame = +2 Query: 2 VIYRPLTSENYL-ANIKVVVNEIVGKYKKGHILIFLQSEEKVLKCMKQLRN--------I 154 + Y P +YL A I+ V+ + + ++G +L+FL +E++ + K+++ + Sbjct: 321 IFYTPEPERDYLEAAIRTVIQIHMCEEEEGDLLLFLTGQEEIDEACKRIKREVDDLGPEV 380 Query: 155 NSTKLLPFFASMDEEEKDRVFFEYGNR-------RKIIIATNLAETSLTIPGVDFVIDSG 313 K++P ++++ +++ R+F + RK++++TN+AETSLTI GV FVID G Sbjct: 381 GDIKIIPLYSTLPPQQQQRIFEPPPPKKQNGAIGRKVVVSTNIAETSLTIDGVVFVIDPG 440 Query: 314 LVKRVRFDHKTGVEKWMTKFISVAEADQXXXXXXXXXXXICYRLYPEKCIKSDQNDLLDE 493 K+ ++ + VE + IS A A Q C+RLY EK K++ D Sbjct: 441 FAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGRTRPGKCFRLYTEKAYKTEMQD---- 496 Query: 494 IRDLNLQNGDENATIDESNKIFSKEGPKKFPKFPDPEIKTVNLNSMTLVLKSMKWDNVFD 673 PEI NL S+ L LK + D++ Sbjct: 497 --------------------------------NTYPEILRSNLGSVVLQLKKLGIDDLVH 524 Query: 674 FPFIVVPEIDKIESALKELEDLSLLNEQRELTKIGEIASCLSLEPRLAKVATIASELPC 850 F F+ P + + AL+ L L+ LN+ +LT++G + + L+P+LAK+ + + C Sbjct: 525 FDFMDPPAPETLMRALELLNYLAALNDDGDLTELGSMMAEFPLDPQLAKMVIASCDYNC 583
>sp|Q38953|DHX8_ARATH Putative pre-mRNA splicing factor ATP-dependent RNA helicase Length = 1168 Score = 111 bits (277), Expect = 3e-24 Identities = 78/292 (26%), Positives = 135/292 (46%), Gaps = 9/292 (3%) Frame = +2 Query: 2 VIYRPLTSENYLANIKVVVNEIVGKYKKGHILIFLQSEEKVLKCMKQL--------RNIN 157 ++Y +YL + V +I +G IL+FL +E++ + L +N+ Sbjct: 696 ILYTKQPETDYLDAALITVLQIHLTEPEGDILVFLTGQEEIDSACQSLYERMKGLGKNVP 755 Query: 158 STKLLPFFASMDEEEKDRVFFEYG-NRRKIIIATNLAETSLTIPGVDFVIDSGLVKRVRF 334 +LP ++++ E + R+F +RK+++ATN+AE SLTI G+ +V+D G K+ + Sbjct: 756 ELIILPVYSALPSEMQSRIFDPPPPGKRKVVVATNIAEASLTIDGIYYVVDPGFAKQNVY 815 Query: 335 DHKTGVEKWMTKFISVAEADQXXXXXXXXXXXICYRLYPEKCIKSDQNDLLDEIRDLNLQ 514 + K G+E + IS A A Q CYRLY E +++ Sbjct: 816 NPKQGLESLVITPISQASAKQRAGRAGRTGPGKCYRLYTESAYRNE-------------- 861 Query: 515 NGDENATIDESNKIFSKEGPKKFPKFPDPEIKTVNLNSMTLVLKSMKWDNVFDFPFIVVP 694 P PEI+ +NL TL +K+M +++ F F+ P Sbjct: 862 ----------------------MPPTSIPEIQRINLGMTTLTMKAMGINDLLSFDFMDPP 899 Query: 695 EIDKIESALKELEDLSLLNEQRELTKIGEIASCLSLEPRLAKVATIASELPC 850 + + SA+++L L L+E+ LTK+G + LEP L+K+ + +L C Sbjct: 900 QPQALISAMEQLYSLGALDEEGLLTKLGRKMAEFPLEPPLSKMLLASVDLGC 951
>sp|Q10752|CDC28_SCHPO Putative ATP-dependent RNA helicase cdc28 Length = 1055 Score = 111 bits (277), Expect = 3e-24 Identities = 83/292 (28%), Positives = 138/292 (47%), Gaps = 9/292 (3%) Frame = +2 Query: 2 VIYRPLTSENYLANIKVVVNEIVGKYKKGHILIFLQSEEKV---LKCMKQL-----RNIN 157 + Y P NY+ + +I G IL+FL ++++ + M++L + I Sbjct: 600 IYYTPQPEANYIQAAITTILQIHTTQPAGDILVFLTGQDEIELMSENMQELCRILGKRIP 659 Query: 158 STKLLPFFASMDEEEKDRVFFEYG-NRRKIIIATNLAETSLTIPGVDFVIDSGLVKRVRF 334 L P +A++ E + ++F RK+++ATN+AETS+TI GV+FVIDSG VK+ + Sbjct: 660 EIILCPIYANLPSELQAKIFDPTPPGARKVVLATNIAETSITIDGVNFVIDSGFVKQNMY 719 Query: 335 DHKTGVEKWMTKFISVAEADQXXXXXXXXXXXICYRLYPEKCIKSDQNDLLDEIRDLNLQ 514 + +TG+E ++ S A ADQ C+RLY + N+ LD + Sbjct: 720 NPRTGMESLVSVPCSRASADQRAGRAGRVGPGKCFRLYTRR----TYNNELDMV------ 769 Query: 515 NGDENATIDESNKIFSKEGPKKFPKFPDPEIKTVNLNSMTLVLKSMKWDNVFDFPFIVVP 694 PEI+ NL ++ L+LKS+ +N+ DF F+ P Sbjct: 770 --------------------------TSPEIQRTNLTNIVLLLKSLGINNLLDFDFMDAP 803 Query: 695 EIDKIESALKELEDLSLLNEQRELTKIGEIASCLSLEPRLAKVATIASELPC 850 + + +L+ L L LN + ELTK+G + +P L+K +S+ C Sbjct: 804 PPETLMRSLELLYALGALNNRGELTKLGRQMAEFPTDPMLSKSLIASSKYGC 855
>sp|Q14562|DHX8_HUMAN ATP-dependent helicase DHX8 (RNA helicase HRH1) (DEAH-box protein 8) Length = 1220 Score = 110 bits (276), Expect = 4e-24 Identities = 82/292 (28%), Positives = 141/292 (48%), Gaps = 9/292 (3%) Frame = +2 Query: 2 VIYRPLTSENYLANIKVVVNEIVGKYKKGHILIFLQSEEKV-------LKCMKQLR-NIN 157 ++Y +YL + V +I G IL+FL +E++ + MK L ++ Sbjct: 746 ILYTKEPETDYLDASLITVMQIHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVP 805 Query: 158 STKLLPFFASMDEEEKDRVFFEYG-NRRKIIIATNLAETSLTIPGVDFVIDSGLVKRVRF 334 +LP ++++ E + R+F RK++IATN+AETSLTI G+ +V+D G VK+ + Sbjct: 806 ELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVY 865 Query: 335 DHKTGVEKWMTKFISVAEADQXXXXXXXXXXXICYRLYPEKCIKSDQNDLLDEIRDLNLQ 514 + KTG+++ + IS A+A Q CYRLY E+ + DE+ N+ Sbjct: 866 NSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYR-------DEMLTTNV- 917 Query: 515 NGDENATIDESNKIFSKEGPKKFPKFPDPEIKTVNLNSMTLVLKSMKWDNVFDFPFIVVP 694 PEI+ NL S L LK+M +++ F F+ P Sbjct: 918 ----------------------------PEIQRTNLASTVLSLKAMGINDLLSFDFMDAP 949 Query: 695 EIDKIESALKELEDLSLLNEQRELTKIGEIASCLSLEPRLAKVATIASELPC 850 ++ + +A+++L L L+++ LT++G + LEP L K+ ++ L C Sbjct: 950 PMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGC 1001
>sp|O42643|DHX8_SCHPO Putative pre-mRNA splicing factor ATP-dependent RNA helicase C10F6.02c Length = 1168 Score = 107 bits (268), Expect = 3e-23 Identities = 84/292 (28%), Positives = 137/292 (46%), Gaps = 9/292 (3%) Frame = +2 Query: 2 VIYRPLTSENYLANIKVVVNEIVGKYKKGHILIFLQSEEKVLKCMKQLR--------NIN 157 ++Y +YL + V +I G IL+FL +E++ + L +I Sbjct: 692 IMYTKQPEADYLDAALMTVMQIHLSEGPGDILVFLTGQEEIDTSCEILYERSKMLGDSIP 751 Query: 158 STKLLPFFASMDEEEKDRVFFEYG-NRRKIIIATNLAETSLTIPGVDFVIDSGLVKRVRF 334 +LP ++++ E + R+F RK++IATN+AETSLTI G+ +V+D G VK+ F Sbjct: 752 ELVILPVYSALPSEIQSRIFEPAPPGGRKVVIATNIAETSLTIDGIYYVVDPGFVKQSCF 811 Query: 335 DHKTGVEKWMTKFISVAEADQXXXXXXXXXXXICYRLYPEKCIKSDQNDLLDEIRDLNLQ 514 D K G++ + IS A+A Q CYRLY E + N++L Sbjct: 812 DPKLGMDSLIVTPISQAQARQRSGRAGRTGPGKCYRLYTESAYR---NEMLPS------- 861 Query: 515 NGDENATIDESNKIFSKEGPKKFPKFPDPEIKTVNLNSMTLVLKSMKWDNVFDFPFIVVP 694 P PEI+ NL+ L+LK+M +++ +F F+ P Sbjct: 862 --------------------------PIPEIQRQNLSHTILMLKAMGINDLLNFDFMDPP 895 Query: 695 EIDKIESALKELEDLSLLNEQRELTKIGEIASCLSLEPRLAKVATIASELPC 850 + +AL+ L LS L+++ LT +G + +EP+L+KV + EL C Sbjct: 896 PAQTMIAALQNLYALSALDDEGLLTPLGRKMADFPMEPQLSKVLITSVELGC 947
>sp|Q9H6R0|DHX33_HUMAN Putative ATP-dependent helicase DHX33 (DEAH-box protein 33) Length = 707 Score = 107 bits (267), Expect = 4e-23 Identities = 88/296 (29%), Positives = 137/296 (46%), Gaps = 13/296 (4%) Frame = +2 Query: 2 VIYRPLTSENYLANIKVVVNEIVGKYKKGH-ILIFLQSEEKVLKCMKQLRNIN------- 157 V Y +YL V V +I + IL+FL +E++ K R+I Sbjct: 260 VFYTKQPQNDYLHAALVSVFQIHQEAPSSQDILVFLTGQEEIEAMSKTCRDIAKHLPDGC 319 Query: 158 -STKLLPFFASMDEEEKDRVFFEYGNR-RKIIIATNLAETSLTIPGVDFVIDSGLVKRVR 331 + +LP +AS+ ++ RVF RK+II+TN+AETS+TI G+ +V+D+G+VK + Sbjct: 320 PAMLVLPLYASLPYAQQLRVFQGAPKGYRKVIISTNIAETSITITGIKYVVDTGMVKAKK 379 Query: 332 FDHKTGVEKWMTKFISVAEADQXXXXXXXXXXXICYRLYPEKCIKSDQNDLLDEIRDLNL 511 ++ +G+E + +S +A Q ICYRLY E DE Sbjct: 380 YNPDSGLEVLAVQRVSKTQAWQRTGRAGREDSGICYRLYTE-----------DEF----- 423 Query: 512 QNGDENATIDESNKIFSKEGPKKFPKFPDPEIKTVNLNSMTLVLKSMKWDNVFDFPFIVV 691 +KF K PEI+ NL S+ L L +MK NV F F+ Sbjct: 424 ---------------------EKFDKMTVPEIQRCNLASVMLQLLAMKVPNVLTFDFMSK 462 Query: 692 PEIDKIESALKELEDLSLL---NEQRELTKIGEIASCLSLEPRLAKVATIASELPC 850 P D I++A+ +L+ L L ++Q LT +G + LEP+ AK ++ + C Sbjct: 463 PSPDHIQAAIAQLDLLGALEHKDDQLTLTPMGRKMAAFPLEPKFAKTILMSPKFHC 518
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 88,267,708 Number of Sequences: 369166 Number of extensions: 1698354 Number of successful extensions: 5933 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 5653 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5914 length of database: 68,354,980 effective HSP length: 109 effective length of database: 48,218,865 effective search space used: 8390082510 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)