Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_008_J09
(851 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P45018|HRPA_HAEIN ATP-dependent helicase hrpA homolog 124 3e-28
sp|P43329|HRPA_ECOLI ATP-dependent helicase hrpA 119 1e-26
sp|Q09530|MOG5_CAEEL Probable pre-mRNA splicing factor ATP-... 114 3e-25
sp|O35286|DHX15_MOUSE Putative pre-mRNA splicing factor RNA... 112 1e-24
sp|O43143|DHX15_HUMAN Putative pre-mRNA splicing factor RNA... 112 1e-24
sp|Q38953|DHX8_ARATH Putative pre-mRNA splicing factor ATP-... 111 3e-24
sp|Q10752|CDC28_SCHPO Putative ATP-dependent RNA helicase c... 111 3e-24
sp|Q14562|DHX8_HUMAN ATP-dependent helicase DHX8 (RNA helic... 110 4e-24
sp|O42643|DHX8_SCHPO Putative pre-mRNA splicing factor ATP-... 107 3e-23
sp|Q9H6R0|DHX33_HUMAN Putative ATP-dependent helicase DHX33... 107 4e-23
>sp|P45018|HRPA_HAEIN ATP-dependent helicase hrpA homolog
Length = 1304
Score = 124 bits (312), Expect = 3e-28
Identities = 87/294 (29%), Positives = 145/294 (49%), Gaps = 11/294 (3%)
Frame = +2
Query: 2 VIYRPLTSENYLANIKVVVNEI--VGKYKKGHILIFLQSEEKVLKCMKQLR--NINSTKL 169
V YRP+ E+ ++ ++N + + +G ILIF+ E ++ + L+ N+ T++
Sbjct: 265 VRYRPVVEEDDQDQLQGILNAVDELQAEGRGDILIFMNGEREIRDTAEALQKQNLKHTEI 324
Query: 170 LPFFASMDEEEKDRVFFEYGNRRKIIIATNLAETSLTIPGVDFVIDSGLVKRVRFDHKTG 349
LP FA + +E++++F G R I++ATN+AETSLT+P + +VID G + R+ ++T
Sbjct: 325 LPLFARLSAQEQNKIFHPSGLNR-IVLATNVAETSLTVPSIKYVIDPGTARISRYSYRTK 383
Query: 350 VEKWMTKFISVAEADQXXXXXXXXXXXICYRLYPEKCIKSDQNDLLDEIRDLNLQNGDEN 529
V++ + IS A A+Q IC RLY E+ D N +
Sbjct: 384 VQRLPIEPISQASANQRKGRCGRVSEGICIRLYSEE--------------DFNSR----- 424
Query: 530 ATIDESNKIFSKEGPKKFPKFPDPEIKTVNLNSMTLVLKSMKWDNVFDFPFIVVPEIDKI 709
P+F DPEI NL S+ L + ++ D++ FPF+ P+ I
Sbjct: 425 ------------------PEFTDPEILRTNLASVILQMTALGLDDIEAFPFVDAPDERHI 466
Query: 710 ESALKELEDLSLL-------NEQRELTKIGEIASCLSLEPRLAKVATIASELPC 850
+ +K LE+L E+R LT++G + L ++PRLAK+ A C
Sbjct: 467 QDGVKLLEELGAFETVQTKSGEKRLLTRVGRQLAQLPVDPRLAKMILSAVNFGC 520
>sp|P43329|HRPA_ECOLI ATP-dependent helicase hrpA
Length = 1300
Score = 119 bits (297), Expect = 1e-26
Identities = 88/296 (29%), Positives = 140/296 (47%), Gaps = 13/296 (4%)
Frame = +2
Query: 2 VIYRPLTSE------NYLANIKVVVNEIVGKYKKGHILIFLQSEEKVLKCMKQLRNIN-- 157
V YRP+ E + L I V+E+ + G ILIF+ E ++ L +N
Sbjct: 258 VRYRPIVEEADDTERDQLQAIFDAVDEL-SQESHGDILIFMSGEREIRDTADALNKLNLR 316
Query: 158 STKLLPFFASMDEEEKDRVFFEYGNRRKIIIATNLAETSLTIPGVDFVIDSGLVKRVRFD 337
T++LP +A + E++RVF + RR I++ATN+AETSLT+PG+ +VID G + R+
Sbjct: 317 HTEILPLYARLSNSEQNRVFQSHSGRR-IVLATNVAETSLTVPGIKYVIDPGTARISRYS 375
Query: 338 HKTGVEKWMTKFISVAEADQXXXXXXXXXXXICYRLYPEKCIKSDQNDLLDEIRDLNLQN 517
++T V++ + IS A A+Q IC RLY E +D L
Sbjct: 376 YRTKVQRLPIEPISQASANQRKGRCGRVSEGICIRLYSE-------DDFLSR-------- 420
Query: 518 GDENATIDESNKIFSKEGPKKFPKFPDPEIKTVNLNSMTLVLKSMKWDNVFDFPFIVVPE 697
P+F DPEI NL S+ L + ++ ++ FPF+ P+
Sbjct: 421 ----------------------PEFTDPEILRTNLASVILQMTALGLGDIAAFPFVEAPD 458
Query: 698 IDKIESALKELEDLSLLNEQRE-----LTKIGEIASCLSLEPRLAKVATIASELPC 850
I+ ++ LE+L + + LT +G S L ++PRLA++ A + C
Sbjct: 459 KRNIQDGVRLLEELGAITTDEQASAYKLTPLGRQLSQLPVDPRLARMVLEAQKHGC 514
>sp|Q09530|MOG5_CAEEL Probable pre-mRNA splicing factor ATP-dependent RNA helicase mog-5
(Sex determination protein mog-5) (Masculinization of
germ line protein 5)
Length = 1200
Score = 114 bits (286), Expect = 3e-25
Identities = 83/292 (28%), Positives = 136/292 (46%), Gaps = 9/292 (3%)
Frame = +2
Query: 2 VIYRPLTSENYLANIKVVVNEIVGKYKKGHILIFLQSEEKV-------LKCMKQLR-NIN 157
++Y +YL + V +I G +L+FL +E++ + MK + ++
Sbjct: 721 ILYTREPESDYLEAAHITVMQIHLTEPPGDVLVFLTGQEEIDTSCEVLYERMKSMGPDVP 780
Query: 158 STKLLPFFASMDEEEKDRVFFEY-GNRRKIIIATNLAETSLTIPGVDFVIDSGLVKRVRF 334
+LP + ++ E + R+F +RK++IATN+AETSLTI G+ +V+D G VK+ +
Sbjct: 781 ELIILPVYGALPSEMQTRIFDPAPAGKRKVVIATNIAETSLTIDGIFYVVDPGFVKQKIY 840
Query: 335 DHKTGVEKWMTKFISVAEADQXXXXXXXXXXXICYRLYPEKCIKSDQNDLLDEIRDLNLQ 514
+ K+G++ + IS A A Q CYRLY E+ + +
Sbjct: 841 NPKSGMDSLVVTPISQAAAKQRSGRAGRTGPGKCYRLYTERAFRDEMLPT---------- 890
Query: 515 NGDENATIDESNKIFSKEGPKKFPKFPDPEIKTVNLNSMTLVLKSMKWDNVFDFPFIVVP 694
P PEI+ NL S L LK+M +N+ DF F+ P
Sbjct: 891 --------------------------PVPEIQRTNLASTLLQLKAMGINNLIDFDFMDAP 924
Query: 695 EIDKIESALKELEDLSLLNEQRELTKIGEIASCLSLEPRLAKVATIASELPC 850
+D + +AL L LS L+ LTK+G + LEP L+K+ ++ +L C
Sbjct: 925 PLDSMITALNTLHTLSALDGDGLLTKLGRRMAEFPLEPSLSKLLIMSVDLGC 976
>sp|O35286|DHX15_MOUSE Putative pre-mRNA splicing factor RNA helicase (DEAH box protein 15)
Length = 795
Score = 112 bits (280), Expect = 1e-24
Identities = 79/299 (26%), Positives = 141/299 (47%), Gaps = 16/299 (5%)
Frame = +2
Query: 2 VIYRPLTSENYL-ANIKVVVNEIVGKYKKGHILIFLQSEEKVLKCMKQLRN--------I 154
+ Y P +YL A I+ V+ + + ++G +L+FL +E++ + K+++ +
Sbjct: 321 IFYTPEPERDYLEAAIRTVIQIHMCEEEEGDLLLFLTGQEEIDEACKRIKREVDDLGPEV 380
Query: 155 NSTKLLPFFASMDEEEKDRVFFEYGNR-------RKIIIATNLAETSLTIPGVDFVIDSG 313
K++P ++++ +++ R+F + RK++++TN+AETSLTI GV FVID G
Sbjct: 381 GDIKIIPLYSTLPPQQQQRIFEPPPPKKQNGAIGRKVVVSTNIAETSLTIDGVVFVIDPG 440
Query: 314 LVKRVRFDHKTGVEKWMTKFISVAEADQXXXXXXXXXXXICYRLYPEKCIKSDQNDLLDE 493
K+ ++ + VE + IS A A Q C+RLY EK K++ D
Sbjct: 441 FAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGRTRPGKCFRLYTEKAYKTEMQD---- 496
Query: 494 IRDLNLQNGDENATIDESNKIFSKEGPKKFPKFPDPEIKTVNLNSMTLVLKSMKWDNVFD 673
PEI NL S+ L LK + D++
Sbjct: 497 --------------------------------NTYPEILRSNLGSVVLQLKKLGIDDLVH 524
Query: 674 FPFIVVPEIDKIESALKELEDLSLLNEQRELTKIGEIASCLSLEPRLAKVATIASELPC 850
F F+ P + + AL+ L L+ LN+ +LT++G + + L+P+LAK+ + + C
Sbjct: 525 FDFMDPPAPETLMRALELLNYLAALNDDGDLTELGSMMAEFPLDPQLAKMVIASCDYNC 583
>sp|O43143|DHX15_HUMAN Putative pre-mRNA splicing factor RNA helicase (DEAH box protein 15)
(ATP-dependent RNA helicase #46)
Length = 795
Score = 112 bits (280), Expect = 1e-24
Identities = 79/299 (26%), Positives = 141/299 (47%), Gaps = 16/299 (5%)
Frame = +2
Query: 2 VIYRPLTSENYL-ANIKVVVNEIVGKYKKGHILIFLQSEEKVLKCMKQLRN--------I 154
+ Y P +YL A I+ V+ + + ++G +L+FL +E++ + K+++ +
Sbjct: 321 IFYTPEPERDYLEAAIRTVIQIHMCEEEEGDLLLFLTGQEEIDEACKRIKREVDDLGPEV 380
Query: 155 NSTKLLPFFASMDEEEKDRVFFEYGNR-------RKIIIATNLAETSLTIPGVDFVIDSG 313
K++P ++++ +++ R+F + RK++++TN+AETSLTI GV FVID G
Sbjct: 381 GDIKIIPLYSTLPPQQQQRIFEPPPPKKQNGAIGRKVVVSTNIAETSLTIDGVVFVIDPG 440
Query: 314 LVKRVRFDHKTGVEKWMTKFISVAEADQXXXXXXXXXXXICYRLYPEKCIKSDQNDLLDE 493
K+ ++ + VE + IS A A Q C+RLY EK K++ D
Sbjct: 441 FAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGRTRPGKCFRLYTEKAYKTEMQD---- 496
Query: 494 IRDLNLQNGDENATIDESNKIFSKEGPKKFPKFPDPEIKTVNLNSMTLVLKSMKWDNVFD 673
PEI NL S+ L LK + D++
Sbjct: 497 --------------------------------NTYPEILRSNLGSVVLQLKKLGIDDLVH 524
Query: 674 FPFIVVPEIDKIESALKELEDLSLLNEQRELTKIGEIASCLSLEPRLAKVATIASELPC 850
F F+ P + + AL+ L L+ LN+ +LT++G + + L+P+LAK+ + + C
Sbjct: 525 FDFMDPPAPETLMRALELLNYLAALNDDGDLTELGSMMAEFPLDPQLAKMVIASCDYNC 583
>sp|Q38953|DHX8_ARATH Putative pre-mRNA splicing factor ATP-dependent RNA helicase
Length = 1168
Score = 111 bits (277), Expect = 3e-24
Identities = 78/292 (26%), Positives = 135/292 (46%), Gaps = 9/292 (3%)
Frame = +2
Query: 2 VIYRPLTSENYLANIKVVVNEIVGKYKKGHILIFLQSEEKVLKCMKQL--------RNIN 157
++Y +YL + V +I +G IL+FL +E++ + L +N+
Sbjct: 696 ILYTKQPETDYLDAALITVLQIHLTEPEGDILVFLTGQEEIDSACQSLYERMKGLGKNVP 755
Query: 158 STKLLPFFASMDEEEKDRVFFEYG-NRRKIIIATNLAETSLTIPGVDFVIDSGLVKRVRF 334
+LP ++++ E + R+F +RK+++ATN+AE SLTI G+ +V+D G K+ +
Sbjct: 756 ELIILPVYSALPSEMQSRIFDPPPPGKRKVVVATNIAEASLTIDGIYYVVDPGFAKQNVY 815
Query: 335 DHKTGVEKWMTKFISVAEADQXXXXXXXXXXXICYRLYPEKCIKSDQNDLLDEIRDLNLQ 514
+ K G+E + IS A A Q CYRLY E +++
Sbjct: 816 NPKQGLESLVITPISQASAKQRAGRAGRTGPGKCYRLYTESAYRNE-------------- 861
Query: 515 NGDENATIDESNKIFSKEGPKKFPKFPDPEIKTVNLNSMTLVLKSMKWDNVFDFPFIVVP 694
P PEI+ +NL TL +K+M +++ F F+ P
Sbjct: 862 ----------------------MPPTSIPEIQRINLGMTTLTMKAMGINDLLSFDFMDPP 899
Query: 695 EIDKIESALKELEDLSLLNEQRELTKIGEIASCLSLEPRLAKVATIASELPC 850
+ + SA+++L L L+E+ LTK+G + LEP L+K+ + +L C
Sbjct: 900 QPQALISAMEQLYSLGALDEEGLLTKLGRKMAEFPLEPPLSKMLLASVDLGC 951
>sp|Q10752|CDC28_SCHPO Putative ATP-dependent RNA helicase cdc28
Length = 1055
Score = 111 bits (277), Expect = 3e-24
Identities = 83/292 (28%), Positives = 138/292 (47%), Gaps = 9/292 (3%)
Frame = +2
Query: 2 VIYRPLTSENYLANIKVVVNEIVGKYKKGHILIFLQSEEKV---LKCMKQL-----RNIN 157
+ Y P NY+ + +I G IL+FL ++++ + M++L + I
Sbjct: 600 IYYTPQPEANYIQAAITTILQIHTTQPAGDILVFLTGQDEIELMSENMQELCRILGKRIP 659
Query: 158 STKLLPFFASMDEEEKDRVFFEYG-NRRKIIIATNLAETSLTIPGVDFVIDSGLVKRVRF 334
L P +A++ E + ++F RK+++ATN+AETS+TI GV+FVIDSG VK+ +
Sbjct: 660 EIILCPIYANLPSELQAKIFDPTPPGARKVVLATNIAETSITIDGVNFVIDSGFVKQNMY 719
Query: 335 DHKTGVEKWMTKFISVAEADQXXXXXXXXXXXICYRLYPEKCIKSDQNDLLDEIRDLNLQ 514
+ +TG+E ++ S A ADQ C+RLY + N+ LD +
Sbjct: 720 NPRTGMESLVSVPCSRASADQRAGRAGRVGPGKCFRLYTRR----TYNNELDMV------ 769
Query: 515 NGDENATIDESNKIFSKEGPKKFPKFPDPEIKTVNLNSMTLVLKSMKWDNVFDFPFIVVP 694
PEI+ NL ++ L+LKS+ +N+ DF F+ P
Sbjct: 770 --------------------------TSPEIQRTNLTNIVLLLKSLGINNLLDFDFMDAP 803
Query: 695 EIDKIESALKELEDLSLLNEQRELTKIGEIASCLSLEPRLAKVATIASELPC 850
+ + +L+ L L LN + ELTK+G + +P L+K +S+ C
Sbjct: 804 PPETLMRSLELLYALGALNNRGELTKLGRQMAEFPTDPMLSKSLIASSKYGC 855
>sp|Q14562|DHX8_HUMAN ATP-dependent helicase DHX8 (RNA helicase HRH1) (DEAH-box protein 8)
Length = 1220
Score = 110 bits (276), Expect = 4e-24
Identities = 82/292 (28%), Positives = 141/292 (48%), Gaps = 9/292 (3%)
Frame = +2
Query: 2 VIYRPLTSENYLANIKVVVNEIVGKYKKGHILIFLQSEEKV-------LKCMKQLR-NIN 157
++Y +YL + V +I G IL+FL +E++ + MK L ++
Sbjct: 746 ILYTKEPETDYLDASLITVMQIHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVP 805
Query: 158 STKLLPFFASMDEEEKDRVFFEYG-NRRKIIIATNLAETSLTIPGVDFVIDSGLVKRVRF 334
+LP ++++ E + R+F RK++IATN+AETSLTI G+ +V+D G VK+ +
Sbjct: 806 ELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVY 865
Query: 335 DHKTGVEKWMTKFISVAEADQXXXXXXXXXXXICYRLYPEKCIKSDQNDLLDEIRDLNLQ 514
+ KTG+++ + IS A+A Q CYRLY E+ + DE+ N+
Sbjct: 866 NSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYR-------DEMLTTNV- 917
Query: 515 NGDENATIDESNKIFSKEGPKKFPKFPDPEIKTVNLNSMTLVLKSMKWDNVFDFPFIVVP 694
PEI+ NL S L LK+M +++ F F+ P
Sbjct: 918 ----------------------------PEIQRTNLASTVLSLKAMGINDLLSFDFMDAP 949
Query: 695 EIDKIESALKELEDLSLLNEQRELTKIGEIASCLSLEPRLAKVATIASELPC 850
++ + +A+++L L L+++ LT++G + LEP L K+ ++ L C
Sbjct: 950 PMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGC 1001
>sp|O42643|DHX8_SCHPO Putative pre-mRNA splicing factor ATP-dependent RNA helicase
C10F6.02c
Length = 1168
Score = 107 bits (268), Expect = 3e-23
Identities = 84/292 (28%), Positives = 137/292 (46%), Gaps = 9/292 (3%)
Frame = +2
Query: 2 VIYRPLTSENYLANIKVVVNEIVGKYKKGHILIFLQSEEKVLKCMKQLR--------NIN 157
++Y +YL + V +I G IL+FL +E++ + L +I
Sbjct: 692 IMYTKQPEADYLDAALMTVMQIHLSEGPGDILVFLTGQEEIDTSCEILYERSKMLGDSIP 751
Query: 158 STKLLPFFASMDEEEKDRVFFEYG-NRRKIIIATNLAETSLTIPGVDFVIDSGLVKRVRF 334
+LP ++++ E + R+F RK++IATN+AETSLTI G+ +V+D G VK+ F
Sbjct: 752 ELVILPVYSALPSEIQSRIFEPAPPGGRKVVIATNIAETSLTIDGIYYVVDPGFVKQSCF 811
Query: 335 DHKTGVEKWMTKFISVAEADQXXXXXXXXXXXICYRLYPEKCIKSDQNDLLDEIRDLNLQ 514
D K G++ + IS A+A Q CYRLY E + N++L
Sbjct: 812 DPKLGMDSLIVTPISQAQARQRSGRAGRTGPGKCYRLYTESAYR---NEMLPS------- 861
Query: 515 NGDENATIDESNKIFSKEGPKKFPKFPDPEIKTVNLNSMTLVLKSMKWDNVFDFPFIVVP 694
P PEI+ NL+ L+LK+M +++ +F F+ P
Sbjct: 862 --------------------------PIPEIQRQNLSHTILMLKAMGINDLLNFDFMDPP 895
Query: 695 EIDKIESALKELEDLSLLNEQRELTKIGEIASCLSLEPRLAKVATIASELPC 850
+ +AL+ L LS L+++ LT +G + +EP+L+KV + EL C
Sbjct: 896 PAQTMIAALQNLYALSALDDEGLLTPLGRKMADFPMEPQLSKVLITSVELGC 947
>sp|Q9H6R0|DHX33_HUMAN Putative ATP-dependent helicase DHX33 (DEAH-box protein 33)
Length = 707
Score = 107 bits (267), Expect = 4e-23
Identities = 88/296 (29%), Positives = 137/296 (46%), Gaps = 13/296 (4%)
Frame = +2
Query: 2 VIYRPLTSENYLANIKVVVNEIVGKYKKGH-ILIFLQSEEKVLKCMKQLRNIN------- 157
V Y +YL V V +I + IL+FL +E++ K R+I
Sbjct: 260 VFYTKQPQNDYLHAALVSVFQIHQEAPSSQDILVFLTGQEEIEAMSKTCRDIAKHLPDGC 319
Query: 158 -STKLLPFFASMDEEEKDRVFFEYGNR-RKIIIATNLAETSLTIPGVDFVIDSGLVKRVR 331
+ +LP +AS+ ++ RVF RK+II+TN+AETS+TI G+ +V+D+G+VK +
Sbjct: 320 PAMLVLPLYASLPYAQQLRVFQGAPKGYRKVIISTNIAETSITITGIKYVVDTGMVKAKK 379
Query: 332 FDHKTGVEKWMTKFISVAEADQXXXXXXXXXXXICYRLYPEKCIKSDQNDLLDEIRDLNL 511
++ +G+E + +S +A Q ICYRLY E DE
Sbjct: 380 YNPDSGLEVLAVQRVSKTQAWQRTGRAGREDSGICYRLYTE-----------DEF----- 423
Query: 512 QNGDENATIDESNKIFSKEGPKKFPKFPDPEIKTVNLNSMTLVLKSMKWDNVFDFPFIVV 691
+KF K PEI+ NL S+ L L +MK NV F F+
Sbjct: 424 ---------------------EKFDKMTVPEIQRCNLASVMLQLLAMKVPNVLTFDFMSK 462
Query: 692 PEIDKIESALKELEDLSLL---NEQRELTKIGEIASCLSLEPRLAKVATIASELPC 850
P D I++A+ +L+ L L ++Q LT +G + LEP+ AK ++ + C
Sbjct: 463 PSPDHIQAAIAQLDLLGALEHKDDQLTLTPMGRKMAAFPLEPKFAKTILMSPKFHC 518
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 88,267,708
Number of Sequences: 369166
Number of extensions: 1698354
Number of successful extensions: 5933
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5653
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5914
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8390082510
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)