Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_01667 (778 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P43254|COP1_ARATH Ubiquitin ligase protein COP1 (Constit... 38 0.027 sp|P79051|RHP16_SCHPO DNA repair protein rhp16 (RAD16 homolog) 37 0.060 sp|Q9R1A8|RFWD2_MOUSE Ring finger and WD repeat domain prot... 37 0.079 sp|P93471|COP1_PEA Ubiquitin ligase protein COP1 (Constitut... 37 0.079 sp|Q8NHY2|RFWD2_HUMAN Ring finger and WD repeat domain prot... 37 0.079 sp|P70196|TRAF6_MOUSE TNF receptor-associated factor 6 35 0.30 sp|Q9Y4K3|TRAF6_HUMAN TNF receptor-associated factor 6 (Int... 34 0.39 sp|Q8N448|LNX2_HUMAN Ligand of Numb-protein X 2 (Numb-bindi... 34 0.39 sp|Q6J6I9|BRCA1_MACMU Breast cancer type 1 susceptibility p... 34 0.51 sp|Q6J6J0|BRCA1_PONPY Breast cancer type 1 susceptibility p... 34 0.51
>sp|P43254|COP1_ARATH Ubiquitin ligase protein COP1 (Constitutive photomorphogenesis protein 1) Length = 675 Score = 38.1 bits (87), Expect = 0.027 Identities = 17/32 (53%), Positives = 21/32 (65%) Frame = +1 Query: 193 DLVCLICGKIIKNACQTICGCKFCLQCIEQYL 288 DL+C IC +IIK+A T CG FC CI +L Sbjct: 49 DLLCPICMQIIKDAFLTACGHSFCYMCIITHL 80
>sp|P79051|RHP16_SCHPO DNA repair protein rhp16 (RAD16 homolog) Length = 861 Score = 37.0 bits (84), Expect = 0.060 Identities = 15/48 (31%), Positives = 29/48 (60%), Gaps = 3/48 (6%) Frame = +1 Query: 172 IDVLSHHDLVCLICGKIIKNACQTICGCKFCLQCIEQYL---GGEENV 306 +D+ + ++VC IC ++ ++A ++ C FC C+ +Y+ G ENV Sbjct: 599 VDIENQENIVCKICDEVAQDAIESRCHHTFCRLCVTEYINAAGDGENV 646
>sp|Q9R1A8|RFWD2_MOUSE Ring finger and WD repeat domain protein 2 (Ubiquitin ligase protein COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1) Length = 733 Score = 36.6 bits (83), Expect = 0.079 Identities = 16/33 (48%), Positives = 20/33 (60%) Frame = +1 Query: 190 HDLVCLICGKIIKNACQTICGCKFCLQCIEQYL 288 +D VC IC +I+ A T CG FC +CI Q L Sbjct: 134 NDFVCPICFDMIEEAYMTKCGHSFCYKCIHQSL 166
>sp|P93471|COP1_PEA Ubiquitin ligase protein COP1 (Constitutive photomorphogenesis protein 1) Length = 672 Score = 36.6 bits (83), Expect = 0.079 Identities = 16/32 (50%), Positives = 20/32 (62%) Frame = +1 Query: 193 DLVCLICGKIIKNACQTICGCKFCLQCIEQYL 288 D +C IC +IIK+A T CG FC CI +L Sbjct: 44 DFLCPICMQIIKDAFLTACGHSFCYMCIITHL 75
>sp|Q8NHY2|RFWD2_HUMAN Ring finger and WD repeat domain protein 2 (Ubiquitin ligase protein COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1) Length = 731 Score = 36.6 bits (83), Expect = 0.079 Identities = 16/33 (48%), Positives = 20/33 (60%) Frame = +1 Query: 190 HDLVCLICGKIIKNACQTICGCKFCLQCIEQYL 288 +D VC IC +I+ A T CG FC +CI Q L Sbjct: 132 NDFVCPICFDMIEEAYMTKCGHSFCYKCIHQSL 164
>sp|P70196|TRAF6_MOUSE TNF receptor-associated factor 6 Length = 530 Score = 34.7 bits (78), Expect = 0.30 Identities = 16/49 (32%), Positives = 25/49 (51%) Frame = +3 Query: 369 DNATNRQISQIKVKCPEPFCQCIVELSKMHCHMKSHKIKCPYSDFRCSQ 515 DN R+I + VKCP C +EL H++ H++ C ++ C Q Sbjct: 120 DNFAKREILSLTVKCPNKGCLQKMELR----HLEDHQVHCEFALVNCPQ 164
Score = 34.3 bits (77), Expect = 0.39 Identities = 19/55 (34%), Positives = 26/55 (47%) Frame = +1 Query: 112 DMSSIIYEEIWNLLDAYQLDIDVLSHHDLVCLICGKIIKNACQTICGCKFCLQCI 276 ++SS EEI Y ++ D C IC ++ A QT CG +FC CI Sbjct: 44 NLSSSFMEEI----QGYDVEFDPPLESKYECPICLMALREAVQTPCGHRFCKACI 94
>sp|Q9Y4K3|TRAF6_HUMAN TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85) Length = 522 Score = 34.3 bits (77), Expect = 0.39 Identities = 19/55 (34%), Positives = 26/55 (47%) Frame = +1 Query: 112 DMSSIIYEEIWNLLDAYQLDIDVLSHHDLVCLICGKIIKNACQTICGCKFCLQCI 276 ++SS EEI Y ++ D C IC ++ A QT CG +FC CI Sbjct: 44 NLSSSFMEEI----QGYDVEFDPPLESKYECPICLMALREAVQTPCGHRFCKACI 94
>sp|Q8N448|LNX2_HUMAN Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain-containing RING finger protein 1) Length = 690 Score = 34.3 bits (77), Expect = 0.39 Identities = 18/48 (37%), Positives = 25/48 (52%) Frame = +1 Query: 145 NLLDAYQLDIDVLSHHDLVCLICGKIIKNACQTICGCKFCLQCIEQYL 288 N L YQ ++D DLVC IC + + T CG FC +C+ +L Sbjct: 35 NHLYNYQNEVD----DDLVCHICLQPLLQPLDTPCGHTFCYKCLRNFL 78
>sp|Q6J6I9|BRCA1_MACMU Breast cancer type 1 susceptibility protein homolog Length = 1863 Score = 33.9 bits (76), Expect = 0.51 Identities = 19/68 (27%), Positives = 36/68 (52%) Frame = +1 Query: 109 IDMSSIIYEEIWNLLDAYQLDIDVLSHHDLVCLICGKIIKNACQTICGCKFCLQCIEQYL 288 +D+S++ EE+ N+++A Q ++ C IC ++IK T C FC C+ + L Sbjct: 1 MDLSAVRVEEVQNVINAMQKILE--------CPICLELIKEPVSTKCDHIFCRFCMLKLL 52 Query: 289 GGEENVAQ 312 ++ +Q Sbjct: 53 NQKKGPSQ 60
>sp|Q6J6J0|BRCA1_PONPY Breast cancer type 1 susceptibility protein homolog Length = 1863 Score = 33.9 bits (76), Expect = 0.51 Identities = 19/68 (27%), Positives = 36/68 (52%) Frame = +1 Query: 109 IDMSSIIYEEIWNLLDAYQLDIDVLSHHDLVCLICGKIIKNACQTICGCKFCLQCIEQYL 288 +D+S++ EE+ N+++A Q ++ C IC ++IK T C FC C+ + L Sbjct: 1 MDLSAVRVEEVQNVINAMQKILE--------CPICLELIKEPVSTKCDHIFCKFCMLKLL 52 Query: 289 GGEENVAQ 312 ++ +Q Sbjct: 53 NQKKGPSQ 60
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 76,258,549 Number of Sequences: 369166 Number of extensions: 1508479 Number of successful extensions: 4096 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 3790 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4094 length of database: 68,354,980 effective HSP length: 108 effective length of database: 48,403,600 effective search space used: 7260540000 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)