Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_008_H07
(778 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P43254|COP1_ARATH Ubiquitin ligase protein COP1 (Constit... 38 0.027
sp|P79051|RHP16_SCHPO DNA repair protein rhp16 (RAD16 homolog) 37 0.060
sp|Q9R1A8|RFWD2_MOUSE Ring finger and WD repeat domain prot... 37 0.079
sp|P93471|COP1_PEA Ubiquitin ligase protein COP1 (Constitut... 37 0.079
sp|Q8NHY2|RFWD2_HUMAN Ring finger and WD repeat domain prot... 37 0.079
sp|P70196|TRAF6_MOUSE TNF receptor-associated factor 6 35 0.30
sp|Q9Y4K3|TRAF6_HUMAN TNF receptor-associated factor 6 (Int... 34 0.39
sp|Q8N448|LNX2_HUMAN Ligand of Numb-protein X 2 (Numb-bindi... 34 0.39
sp|Q6J6I9|BRCA1_MACMU Breast cancer type 1 susceptibility p... 34 0.51
sp|Q6J6J0|BRCA1_PONPY Breast cancer type 1 susceptibility p... 34 0.51
>sp|P43254|COP1_ARATH Ubiquitin ligase protein COP1 (Constitutive photomorphogenesis
protein 1)
Length = 675
Score = 38.1 bits (87), Expect = 0.027
Identities = 17/32 (53%), Positives = 21/32 (65%)
Frame = +1
Query: 193 DLVCLICGKIIKNACQTICGCKFCLQCIEQYL 288
DL+C IC +IIK+A T CG FC CI +L
Sbjct: 49 DLLCPICMQIIKDAFLTACGHSFCYMCIITHL 80
>sp|P79051|RHP16_SCHPO DNA repair protein rhp16 (RAD16 homolog)
Length = 861
Score = 37.0 bits (84), Expect = 0.060
Identities = 15/48 (31%), Positives = 29/48 (60%), Gaps = 3/48 (6%)
Frame = +1
Query: 172 IDVLSHHDLVCLICGKIIKNACQTICGCKFCLQCIEQYL---GGEENV 306
+D+ + ++VC IC ++ ++A ++ C FC C+ +Y+ G ENV
Sbjct: 599 VDIENQENIVCKICDEVAQDAIESRCHHTFCRLCVTEYINAAGDGENV 646
>sp|Q9R1A8|RFWD2_MOUSE Ring finger and WD repeat domain protein 2 (Ubiquitin ligase
protein COP1) (Constitutive photomorphogenesis protein 1
homolog) (mCOP1)
Length = 733
Score = 36.6 bits (83), Expect = 0.079
Identities = 16/33 (48%), Positives = 20/33 (60%)
Frame = +1
Query: 190 HDLVCLICGKIIKNACQTICGCKFCLQCIEQYL 288
+D VC IC +I+ A T CG FC +CI Q L
Sbjct: 134 NDFVCPICFDMIEEAYMTKCGHSFCYKCIHQSL 166
>sp|P93471|COP1_PEA Ubiquitin ligase protein COP1 (Constitutive photomorphogenesis
protein 1)
Length = 672
Score = 36.6 bits (83), Expect = 0.079
Identities = 16/32 (50%), Positives = 20/32 (62%)
Frame = +1
Query: 193 DLVCLICGKIIKNACQTICGCKFCLQCIEQYL 288
D +C IC +IIK+A T CG FC CI +L
Sbjct: 44 DFLCPICMQIIKDAFLTACGHSFCYMCIITHL 75
>sp|Q8NHY2|RFWD2_HUMAN Ring finger and WD repeat domain protein 2 (Ubiquitin ligase
protein COP1) (Constitutive photomorphogenesis protein 1
homolog) (hCOP1)
Length = 731
Score = 36.6 bits (83), Expect = 0.079
Identities = 16/33 (48%), Positives = 20/33 (60%)
Frame = +1
Query: 190 HDLVCLICGKIIKNACQTICGCKFCLQCIEQYL 288
+D VC IC +I+ A T CG FC +CI Q L
Sbjct: 132 NDFVCPICFDMIEEAYMTKCGHSFCYKCIHQSL 164
>sp|P70196|TRAF6_MOUSE TNF receptor-associated factor 6
Length = 530
Score = 34.7 bits (78), Expect = 0.30
Identities = 16/49 (32%), Positives = 25/49 (51%)
Frame = +3
Query: 369 DNATNRQISQIKVKCPEPFCQCIVELSKMHCHMKSHKIKCPYSDFRCSQ 515
DN R+I + VKCP C +EL H++ H++ C ++ C Q
Sbjct: 120 DNFAKREILSLTVKCPNKGCLQKMELR----HLEDHQVHCEFALVNCPQ 164
Score = 34.3 bits (77), Expect = 0.39
Identities = 19/55 (34%), Positives = 26/55 (47%)
Frame = +1
Query: 112 DMSSIIYEEIWNLLDAYQLDIDVLSHHDLVCLICGKIIKNACQTICGCKFCLQCI 276
++SS EEI Y ++ D C IC ++ A QT CG +FC CI
Sbjct: 44 NLSSSFMEEI----QGYDVEFDPPLESKYECPICLMALREAVQTPCGHRFCKACI 94
>sp|Q9Y4K3|TRAF6_HUMAN TNF receptor-associated factor 6 (Interleukin 1 signal transducer)
(RING finger protein 85)
Length = 522
Score = 34.3 bits (77), Expect = 0.39
Identities = 19/55 (34%), Positives = 26/55 (47%)
Frame = +1
Query: 112 DMSSIIYEEIWNLLDAYQLDIDVLSHHDLVCLICGKIIKNACQTICGCKFCLQCI 276
++SS EEI Y ++ D C IC ++ A QT CG +FC CI
Sbjct: 44 NLSSSFMEEI----QGYDVEFDPPLESKYECPICLMALREAVQTPCGHRFCKACI 94
>sp|Q8N448|LNX2_HUMAN Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ
domain-containing RING finger protein 1)
Length = 690
Score = 34.3 bits (77), Expect = 0.39
Identities = 18/48 (37%), Positives = 25/48 (52%)
Frame = +1
Query: 145 NLLDAYQLDIDVLSHHDLVCLICGKIIKNACQTICGCKFCLQCIEQYL 288
N L YQ ++D DLVC IC + + T CG FC +C+ +L
Sbjct: 35 NHLYNYQNEVD----DDLVCHICLQPLLQPLDTPCGHTFCYKCLRNFL 78
>sp|Q6J6I9|BRCA1_MACMU Breast cancer type 1 susceptibility protein homolog
Length = 1863
Score = 33.9 bits (76), Expect = 0.51
Identities = 19/68 (27%), Positives = 36/68 (52%)
Frame = +1
Query: 109 IDMSSIIYEEIWNLLDAYQLDIDVLSHHDLVCLICGKIIKNACQTICGCKFCLQCIEQYL 288
+D+S++ EE+ N+++A Q ++ C IC ++IK T C FC C+ + L
Sbjct: 1 MDLSAVRVEEVQNVINAMQKILE--------CPICLELIKEPVSTKCDHIFCRFCMLKLL 52
Query: 289 GGEENVAQ 312
++ +Q
Sbjct: 53 NQKKGPSQ 60
>sp|Q6J6J0|BRCA1_PONPY Breast cancer type 1 susceptibility protein homolog
Length = 1863
Score = 33.9 bits (76), Expect = 0.51
Identities = 19/68 (27%), Positives = 36/68 (52%)
Frame = +1
Query: 109 IDMSSIIYEEIWNLLDAYQLDIDVLSHHDLVCLICGKIIKNACQTICGCKFCLQCIEQYL 288
+D+S++ EE+ N+++A Q ++ C IC ++IK T C FC C+ + L
Sbjct: 1 MDLSAVRVEEVQNVINAMQKILE--------CPICLELIKEPVSTKCDHIFCKFCMLKLL 52
Query: 289 GGEENVAQ 312
++ +Q
Sbjct: 53 NQKKGPSQ 60
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 76,258,549
Number of Sequences: 369166
Number of extensions: 1508479
Number of successful extensions: 4096
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3790
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4094
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7260540000
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)