Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_01663 (847 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q19269|NAS14_CAEEL Zinc metalloproteinase nas-14 precurs... 100 5e-21 sp|P31579|LCE_ORYLA Low choriolytic enzyme precursor (Hatch... 93 1e-18 sp|P55115|NAS15_CAEEL Zinc metalloproteinase nas-15 precurs... 90 7e-18 sp|Q6HA08|ASTL_HUMAN Astacin-like metalloendopeptidase prec... 88 3e-17 sp|P55113|NAS7_CAEEL Zinc metalloproteinase nas-7 precursor... 88 3e-17 sp|Q9U3S9|NAS6_CAEEL Zinc metalloproteinase nas-6 precursor... 87 4e-17 sp|P98070|BMP1_XENLA Bone morphogenetic protein 1 precursor... 87 8e-17 sp|Q20191|NAS13_CAEEL Zinc metalloproteinase nas-13 precurs... 87 8e-17 sp|P13497|BMP1_HUMAN Bone morphogenetic protein 1 precursor... 86 1e-16 sp|P42674|BP10_PARLI Blastula protease 10 precursor 84 5e-16
>sp|Q19269|NAS14_CAEEL Zinc metalloproteinase nas-14 precursor (Nematode astacin 14) Length = 503 Score = 100 bits (249), Expect = 5e-21 Identities = 62/192 (32%), Positives = 97/192 (50%), Gaps = 11/192 (5%) Frame = -2 Query: 579 WPSRVLRYTFDPSYPDKNKNGIRDFLKTYEKELGNCLKFVEEKNDVFATVVL----GGGC 412 WP + Y + + + I Y+ + C++FV + +D F + + GC Sbjct: 125 WPEGQVPYMLEEGMTNDQRTAIAQAFDEYKTK--TCVRFVPKTDDDFDYIYVKRNVAFGC 182 Query: 411 SANVGY---NKNYPLKITLPDPCVNKRNVKHEFTHLLGFMHEHTRPDRDNFLKINFENVH 241 S+ VG N+ L++ D C +K + HE H LGF HEH+R DRD+F+ IN +N+ Sbjct: 183 SSYVGRAGGNQTVSLEV---DKCFSKGIIAHELMHALGFFHEHSRTDRDDFVDINEDNIR 239 Query: 240 SGLCNNFYLCEG---CKLTTTYDFDSIMQYPSEAFSCNGKDTIL-KKNGGKIPFNMEVTK 73 G+ NF L YD++S+M Y AFS NGK TI+ K N + ++++ Sbjct: 240 PGMMRNFEKYPRKIIDSLGMPYDYESVMHYHKLAFSRNGKPTIIPKDNEADVGQRYKLSE 299 Query: 72 LDAKKVRDYYGC 37 +D+KKV Y C Sbjct: 300 MDSKKVNKLYQC 311
>sp|P31579|LCE_ORYLA Low choriolytic enzyme precursor (Hatching enzyme zinc-protease LCE subunit) (Choriolysin L) Length = 271 Score = 92.8 bits (229), Expect = 1e-18 Identities = 58/197 (29%), Positives = 91/197 (46%), Gaps = 8/197 (4%) Frame = -2 Query: 603 FRAAQGTQWPSRV-----LRYTFDPSYPDKNKNGIRDFLKTYEKELGNCLKFVEEKND-V 442 F A +WP + Y +Y K IR+ +K + ++ C+ FV N+ Sbjct: 77 FGAPDSCRWPKSSNGIVKVPYVVSDNYESDEKETIRNAMKEFAEK--TCIHFVPRNNERA 134 Query: 441 FATVVLGGGCSANVGYNKNYPLKITLPDPCVNKRNVKHEFTHLLGFMHEHTRPDRDNFLK 262 + ++ GC + +GY + + + C+ ++HE H LGF HEHTR DRD +K Sbjct: 135 YLSLEPRFGCKSMMGYVGDKQVVVLQRFGCIKHAVIQHELLHALGFYHEHTRSDRDQHVK 194 Query: 261 INFENVHSGLCNNFYLCEGCKLTTTYDFDSIMQYPSEAFSCNGKDTILKKNGGKIPFNM- 85 IN+EN+ +NF + L T YD+ SIM Y AF + K+TI K Sbjct: 195 INWENIIKDFTHNFDKNDTDNLGTPYDYGSIMHYGRTAFGKDRKETITPIPNPKAAIGQT 254 Query: 84 -EVTKLDAKKVRDYYGC 37 ++ +D +V Y C Sbjct: 255 ERMSDIDILRVNKLYKC 271
>sp|P55115|NAS15_CAEEL Zinc metalloproteinase nas-15 precursor (Nematode astacin 15) Length = 571 Score = 90.1 bits (222), Expect = 7e-18 Identities = 60/187 (32%), Positives = 94/187 (50%), Gaps = 6/187 (3%) Frame = -2 Query: 579 WPSRVLRYTFDPSYPDKNKNGIRDFLKTYEKELGNCLKFV-EEKNDV-FATVVLGGGCSA 406 WP + YT Y +++ I ++ Y C+++V +E DV + + GC + Sbjct: 123 WPEGRIPYTISSQYSSYSRSLIAASMQEYASH--TCIRWVPKEAADVNYVHIYPDRGCYS 180 Query: 405 NVGYNKNYPLKITLPDPCVNKRNVKHEFTHLLGFMHEHTRPDRDNFLKINFENVHSGLCN 226 VG ++L C+ K + HE H +GF HE +R DRD+ + I + N+ +G+ Sbjct: 181 MVG-KMGGKQSLSLGSGCIQKGIILHELMHAVGFFHEQSRTDRDDHITIMWNNIQAGMQG 239 Query: 225 NF-YLCEGC--KLTTTYDFDSIMQYPSEAFSCNGKDTIL-KKNGGKIPFNMEVTKLDAKK 58 F G L T YD+ SIM Y ++AFS NG+ T++ KKNG I +K+D K Sbjct: 240 QFEKYGHGTIQSLGTGYDYGSIMHYGTKAFSRNGQPTMIPKKNGATIGQRNGFSKVDKFK 299 Query: 57 VRDYYGC 37 + YGC Sbjct: 300 INTLYGC 306
>sp|Q6HA08|ASTL_HUMAN Astacin-like metalloendopeptidase precursor (Oocyte astacin) (Ovastacin) Length = 431 Score = 88.2 bits (217), Expect = 3e-17 Identities = 63/209 (30%), Positives = 104/209 (49%), Gaps = 13/209 (6%) Frame = -2 Query: 624 DVLKINGFR--AAQGTQWP---SRVLRYTF--DPSYPDKNKNGIRDFLKTYEKELGNCLK 466 D+++ + FR +A +WP S V+ F Y + ++ I + L +E+ C++ Sbjct: 77 DIIRPSPFRLLSAASNKWPMGGSGVVEVPFLLSSKYDEPSRQVILEALAEFERS--TCIR 134 Query: 465 FV--EEKNDVFATVVLGGGCSANVGYNKNYPLKITLPDPCVNKRN--VKHEFTHLLGFMH 298 FV +++ D F +++ GC ++VG + + ++L C+ K V HE H+LGF H Sbjct: 135 FVTYQDQRD-FISIIPMYGCFSSVGRSGGMQV-VSLAPTCLQKGRGIVLHELMHVLGFWH 192 Query: 297 EHTRPDRDNFLKINFENVHSGLCNNFYLCEGCKLTTTYDFDSIMQYPSEAFSCNGKDTI- 121 EHTR DRD ++++N+ + G NF + T YD+ S+M Y AFS G TI Sbjct: 193 EHTRADRDRYIRVNWNEILPGFEINFIKSRSSNMLTPYDYSSVMHYGRLAFSRRGLPTIT 252 Query: 120 -LKKNGGKIPFNMEVTKLDAKKVRDYYGC 37 L I ++ D +V YGC Sbjct: 253 PLWAPSVHIGQRWNLSASDITRVLKLYGC 281
>sp|P55113|NAS7_CAEEL Zinc metalloproteinase nas-7 precursor (Nematode astacin 7) Length = 382 Score = 87.8 bits (216), Expect = 3e-17 Identities = 55/187 (29%), Positives = 90/187 (48%), Gaps = 6/187 (3%) Frame = -2 Query: 579 WPSRVLRYTFDPSYPDKNKNGIRDFLKTYEKELGNCLKFVEEKNDVFATVVLG--GGCSA 406 WP+ + Y P Y + + +K Y ++ C++FV + + +G GC + Sbjct: 89 WPNARIPYAISPHYSPHERALLAKAVKQYHEK--TCIRFVPRQTGEPDYLFIGKVDGCFS 146 Query: 405 NVGYNKNYPLKITLPDPCVNKRNVKHEFTHLLGFMHEHTRPDRDNFLKINFENVHSGLCN 226 VG + ++L + C+ + HE H++GF HEH R DRDNF+ I ++N+ G + Sbjct: 147 EVGRTSGVQV-LSLDNGCMEYATIIHEMMHVVGFYHEHERWDRDNFIDIIWQNIDRGALD 205 Query: 225 NFYLCEGCKLT---TTYDFDSIMQYPSEAFSCNGKDTILKK-NGGKIPFNMEVTKLDAKK 58 F + K + YD+ SI+ Y S AFS NG T+L K I + + +D K Sbjct: 206 QFGKVDLSKTSYYGQPYDYKSILHYDSLAFSKNGFPTMLPKVKSATIGNARDFSDVDISK 265 Query: 57 VRDYYGC 37 + Y C Sbjct: 266 INRMYNC 272
>sp|Q9U3S9|NAS6_CAEEL Zinc metalloproteinase nas-6 precursor (Nematode astacin 6) Length = 344 Score = 87.4 bits (215), Expect = 4e-17 Identities = 59/198 (29%), Positives = 92/198 (46%), Gaps = 9/198 (4%) Frame = -2 Query: 603 FRAAQGTQ--WPSRVLRYTFDPSYPDKNKNGIRDFLKTYEKELGNCLKFVEEKNDV-FAT 433 F A + Q W V+ Y D ++ + +Y + C++F + + + Sbjct: 71 FNALKNKQLTWEGGVIPYEMDTAFSPNEIKILEKAFDSYRRT--TCIRFEKREGQTDYLN 128 Query: 432 VVLGGGCSANVGYNKNYPLKITLPDPCVNKRNVKHEFTHLLGFMHEHTRPDRDNFLKINF 253 +V G GC + VG +I+L C + HE H +GF HEH+R DRD+ +KIN+ Sbjct: 129 IVKGYGCYSQVGRTGGKQ-EISLGRGCFFHEIIVHELMHSVGFWHEHSRADRDDHIKINW 187 Query: 252 ENVHSGLCNNFYLCEGCKLT---TTYDFDSIMQYPSEAFSCNGKDTILKKNGG---KIPF 91 +N+ G+ + F YD+ SIM Y S AFS NG++TI G I Sbjct: 188 DNILPGMKSQFDKISAVLQDLQGENYDYKSIMHYDSTAFSRNGRNTIETVENGFTQVIGT 247 Query: 90 NMEVTKLDAKKVRDYYGC 37 M+++ LD K+ Y C Sbjct: 248 AMDLSPLDIVKINKLYSC 265
>sp|P98070|BMP1_XENLA Bone morphogenetic protein 1 precursor (BMP-1) Length = 707 Score = 86.7 bits (213), Expect = 8e-17 Identities = 63/192 (32%), Positives = 88/192 (45%), Gaps = 11/192 (5%) Frame = -2 Query: 579 WPSRVLRYTFDPSYPDKNKNGIRDFLKTYEKELGNCLKFVE--EKNDVFATVVLGGGCSA 406 WP V+ Y ++ + R ++ +EK C+ F+E +++ GC + Sbjct: 93 WPDGVIPYVISGNFSGSQRAIFRQAMRHWEKH--TCVTFLERTDEDSYIVFTYRPCGCCS 150 Query: 405 NVGYNKNYPLKITLPDPCVNKRNVKHEFTHLLGFMHEHTRPDRDNFLKINFENVHSGLCN 226 VG P I++ C V HE H++GF HEHTRPDRD+ + I EN+ G Sbjct: 151 YVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDDHVSIIRENIQPGQEY 210 Query: 225 NFYLCEGCK---LTTTYDFDSIMQYPSEAFSCN-GKDTILKK---NGGKIPFNM--EVTK 73 NF E + L TYDFDSIM Y FS DTIL K NG + P ++ Sbjct: 211 NFLKMEPEEVESLGETYDFDSIMHYARNTFSRGIFLDTILPKYDVNGVRPPIGQRTRLSS 270 Query: 72 LDAKKVRDYYGC 37 D + R Y C Sbjct: 271 GDVAQARKLYKC 282
>sp|Q20191|NAS13_CAEEL Zinc metalloproteinase nas-13 precursor (Nematode astacin 13) Length = 527 Score = 86.7 bits (213), Expect = 8e-17 Identities = 61/189 (32%), Positives = 95/189 (50%), Gaps = 7/189 (3%) Frame = -2 Query: 582 QWPSRVLRYTFDPSYPDKNKNGIRDFLKTYEKELGNCLKFVEEK-NDV-FATVVLGGGCS 409 +W + YT Y +++ I + ++ Y K+ C+ F + D+ + +V GC Sbjct: 195 KWEQARIPYTISSQYSSYSRSKIAEAIEEYRKK--TCIDFSPKSAGDLDYIHIVPDDGCY 252 Query: 408 ANVGYNKNYPLKITLPDPCVNKRNVKHEFTHLLGFMHEHTRPDRDNFLKINFENVHSGLC 229 + VG ++L D C+ K + HE H +GF HE +R DRD ++KIN+ NV +GL Sbjct: 253 SLVG-RIGGKQPVSLGDGCIQKGIIIHELMHAVGFFHEQSRADRDEYVKINWSNVEAGLQ 311 Query: 228 NNF---YLCEGCKLTTTYDFDSIMQYPSEAFSCNGKDTI--LKKNGGKIPFNMEVTKLDA 64 + F L L T YD+ S+M Y AFS NGK TI ++KN +I ++ D Sbjct: 312 DQFDKYSLNMIDHLGTKYDYGSVMHYAPTAFSKNGKPTIEPIEKN-VEIGQRAGFSENDI 370 Query: 63 KKVRDYYGC 37 K+ Y C Sbjct: 371 YKINMLYNC 379
>sp|P13497|BMP1_HUMAN Bone morphogenetic protein 1 precursor (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld) Length = 986 Score = 86.3 bits (212), Expect = 1e-16 Identities = 63/192 (32%), Positives = 88/192 (45%), Gaps = 11/192 (5%) Frame = -2 Query: 579 WPSRVLRYTFDPSYPDKNKNGIRDFLKTYEKELGNCLKFVE--EKNDVFATVVLGGGCSA 406 WP V+ + ++ + R ++ +EK C+ F+E +++ GC + Sbjct: 130 WPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKH--TCVTFLERTDEDSYIVFTYRPCGCCS 187 Query: 405 NVGYNKNYPLKITLPDPCVNKRNVKHEFTHLLGFMHEHTRPDRDNFLKINFENVHSGLCN 226 VG P I++ C V HE H++GF HEHTRPDRD + I EN+ G Sbjct: 188 YVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEY 247 Query: 225 NFYLCEGCK---LTTTYDFDSIMQYPSEAFSCN-GKDTILKK---NGGKIPFNM--EVTK 73 NF E + L TYDFDSIM Y FS DTI+ K NG K P ++K Sbjct: 248 NFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSK 307 Query: 72 LDAKKVRDYYGC 37 D + R Y C Sbjct: 308 GDIAQARKLYKC 319
>sp|P42674|BP10_PARLI Blastula protease 10 precursor Length = 597 Score = 84.0 bits (206), Expect = 5e-16 Identities = 50/172 (29%), Positives = 87/172 (50%), Gaps = 11/172 (6%) Frame = -2 Query: 591 QGTQWPSRVLRYTFDPSYPDKNKNGIRDFLKTYEKELGNCLKFVEEKN--------DVFA 436 + +WP +V+ Y PS ++ IR+ + +E+ CL+F + + + Sbjct: 98 ESQRWPYKVIPYVISPSSSGQSSL-IRNAMDHWEQN--TCLRFEPRTSSHSRQLGHNAYL 154 Query: 435 TVVLGGGCSANVGYNKNYPLKITLPDPCVNKRNVKHEFTHLLGFMHEHTRPDRDNFLKIN 256 + G GC + VG N +I++ + C + HE H +GF HE +RPDRD+++ + Sbjct: 155 SFFRGSGCWSYVGKAFNGEQQISIGNGCAYFGTIVHEIGHAIGFHHEQSRPDRDDYINVL 214 Query: 255 FENVHSGLCNNFYLCEGCKLTT---TYDFDSIMQYPSEAFSCNGKDTILKKN 109 ++N+ SG +NF ++T+ YD SIM Y FS NG+ TI ++ Sbjct: 215 YQNIQSGRQHNFAKYTWGRVTSRNVEYDVGSIMHYGGYGFSSNGRPTITTRD 266
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 87,909,378 Number of Sequences: 369166 Number of extensions: 1708556 Number of successful extensions: 5003 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 4763 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4955 length of database: 68,354,980 effective HSP length: 109 effective length of database: 48,218,865 effective search space used: 8293644780 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)