Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_008_G18
(847 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q19269|NAS14_CAEEL Zinc metalloproteinase nas-14 precurs... 100 5e-21
sp|P31579|LCE_ORYLA Low choriolytic enzyme precursor (Hatch... 93 1e-18
sp|P55115|NAS15_CAEEL Zinc metalloproteinase nas-15 precurs... 90 7e-18
sp|Q6HA08|ASTL_HUMAN Astacin-like metalloendopeptidase prec... 88 3e-17
sp|P55113|NAS7_CAEEL Zinc metalloproteinase nas-7 precursor... 88 3e-17
sp|Q9U3S9|NAS6_CAEEL Zinc metalloproteinase nas-6 precursor... 87 4e-17
sp|P98070|BMP1_XENLA Bone morphogenetic protein 1 precursor... 87 8e-17
sp|Q20191|NAS13_CAEEL Zinc metalloproteinase nas-13 precurs... 87 8e-17
sp|P13497|BMP1_HUMAN Bone morphogenetic protein 1 precursor... 86 1e-16
sp|P42674|BP10_PARLI Blastula protease 10 precursor 84 5e-16
>sp|Q19269|NAS14_CAEEL Zinc metalloproteinase nas-14 precursor (Nematode astacin 14)
Length = 503
Score = 100 bits (249), Expect = 5e-21
Identities = 62/192 (32%), Positives = 97/192 (50%), Gaps = 11/192 (5%)
Frame = -2
Query: 579 WPSRVLRYTFDPSYPDKNKNGIRDFLKTYEKELGNCLKFVEEKNDVFATVVL----GGGC 412
WP + Y + + + I Y+ + C++FV + +D F + + GC
Sbjct: 125 WPEGQVPYMLEEGMTNDQRTAIAQAFDEYKTK--TCVRFVPKTDDDFDYIYVKRNVAFGC 182
Query: 411 SANVGY---NKNYPLKITLPDPCVNKRNVKHEFTHLLGFMHEHTRPDRDNFLKINFENVH 241
S+ VG N+ L++ D C +K + HE H LGF HEH+R DRD+F+ IN +N+
Sbjct: 183 SSYVGRAGGNQTVSLEV---DKCFSKGIIAHELMHALGFFHEHSRTDRDDFVDINEDNIR 239
Query: 240 SGLCNNFYLCEG---CKLTTTYDFDSIMQYPSEAFSCNGKDTIL-KKNGGKIPFNMEVTK 73
G+ NF L YD++S+M Y AFS NGK TI+ K N + ++++
Sbjct: 240 PGMMRNFEKYPRKIIDSLGMPYDYESVMHYHKLAFSRNGKPTIIPKDNEADVGQRYKLSE 299
Query: 72 LDAKKVRDYYGC 37
+D+KKV Y C
Sbjct: 300 MDSKKVNKLYQC 311
>sp|P31579|LCE_ORYLA Low choriolytic enzyme precursor (Hatching enzyme zinc-protease LCE
subunit) (Choriolysin L)
Length = 271
Score = 92.8 bits (229), Expect = 1e-18
Identities = 58/197 (29%), Positives = 91/197 (46%), Gaps = 8/197 (4%)
Frame = -2
Query: 603 FRAAQGTQWPSRV-----LRYTFDPSYPDKNKNGIRDFLKTYEKELGNCLKFVEEKND-V 442
F A +WP + Y +Y K IR+ +K + ++ C+ FV N+
Sbjct: 77 FGAPDSCRWPKSSNGIVKVPYVVSDNYESDEKETIRNAMKEFAEK--TCIHFVPRNNERA 134
Query: 441 FATVVLGGGCSANVGYNKNYPLKITLPDPCVNKRNVKHEFTHLLGFMHEHTRPDRDNFLK 262
+ ++ GC + +GY + + + C+ ++HE H LGF HEHTR DRD +K
Sbjct: 135 YLSLEPRFGCKSMMGYVGDKQVVVLQRFGCIKHAVIQHELLHALGFYHEHTRSDRDQHVK 194
Query: 261 INFENVHSGLCNNFYLCEGCKLTTTYDFDSIMQYPSEAFSCNGKDTILKKNGGKIPFNM- 85
IN+EN+ +NF + L T YD+ SIM Y AF + K+TI K
Sbjct: 195 INWENIIKDFTHNFDKNDTDNLGTPYDYGSIMHYGRTAFGKDRKETITPIPNPKAAIGQT 254
Query: 84 -EVTKLDAKKVRDYYGC 37
++ +D +V Y C
Sbjct: 255 ERMSDIDILRVNKLYKC 271
>sp|P55115|NAS15_CAEEL Zinc metalloproteinase nas-15 precursor (Nematode astacin 15)
Length = 571
Score = 90.1 bits (222), Expect = 7e-18
Identities = 60/187 (32%), Positives = 94/187 (50%), Gaps = 6/187 (3%)
Frame = -2
Query: 579 WPSRVLRYTFDPSYPDKNKNGIRDFLKTYEKELGNCLKFV-EEKNDV-FATVVLGGGCSA 406
WP + YT Y +++ I ++ Y C+++V +E DV + + GC +
Sbjct: 123 WPEGRIPYTISSQYSSYSRSLIAASMQEYASH--TCIRWVPKEAADVNYVHIYPDRGCYS 180
Query: 405 NVGYNKNYPLKITLPDPCVNKRNVKHEFTHLLGFMHEHTRPDRDNFLKINFENVHSGLCN 226
VG ++L C+ K + HE H +GF HE +R DRD+ + I + N+ +G+
Sbjct: 181 MVG-KMGGKQSLSLGSGCIQKGIILHELMHAVGFFHEQSRTDRDDHITIMWNNIQAGMQG 239
Query: 225 NF-YLCEGC--KLTTTYDFDSIMQYPSEAFSCNGKDTIL-KKNGGKIPFNMEVTKLDAKK 58
F G L T YD+ SIM Y ++AFS NG+ T++ KKNG I +K+D K
Sbjct: 240 QFEKYGHGTIQSLGTGYDYGSIMHYGTKAFSRNGQPTMIPKKNGATIGQRNGFSKVDKFK 299
Query: 57 VRDYYGC 37
+ YGC
Sbjct: 300 INTLYGC 306
>sp|Q6HA08|ASTL_HUMAN Astacin-like metalloendopeptidase precursor (Oocyte astacin)
(Ovastacin)
Length = 431
Score = 88.2 bits (217), Expect = 3e-17
Identities = 63/209 (30%), Positives = 104/209 (49%), Gaps = 13/209 (6%)
Frame = -2
Query: 624 DVLKINGFR--AAQGTQWP---SRVLRYTF--DPSYPDKNKNGIRDFLKTYEKELGNCLK 466
D+++ + FR +A +WP S V+ F Y + ++ I + L +E+ C++
Sbjct: 77 DIIRPSPFRLLSAASNKWPMGGSGVVEVPFLLSSKYDEPSRQVILEALAEFERS--TCIR 134
Query: 465 FV--EEKNDVFATVVLGGGCSANVGYNKNYPLKITLPDPCVNKRN--VKHEFTHLLGFMH 298
FV +++ D F +++ GC ++VG + + ++L C+ K V HE H+LGF H
Sbjct: 135 FVTYQDQRD-FISIIPMYGCFSSVGRSGGMQV-VSLAPTCLQKGRGIVLHELMHVLGFWH 192
Query: 297 EHTRPDRDNFLKINFENVHSGLCNNFYLCEGCKLTTTYDFDSIMQYPSEAFSCNGKDTI- 121
EHTR DRD ++++N+ + G NF + T YD+ S+M Y AFS G TI
Sbjct: 193 EHTRADRDRYIRVNWNEILPGFEINFIKSRSSNMLTPYDYSSVMHYGRLAFSRRGLPTIT 252
Query: 120 -LKKNGGKIPFNMEVTKLDAKKVRDYYGC 37
L I ++ D +V YGC
Sbjct: 253 PLWAPSVHIGQRWNLSASDITRVLKLYGC 281
>sp|P55113|NAS7_CAEEL Zinc metalloproteinase nas-7 precursor (Nematode astacin 7)
Length = 382
Score = 87.8 bits (216), Expect = 3e-17
Identities = 55/187 (29%), Positives = 90/187 (48%), Gaps = 6/187 (3%)
Frame = -2
Query: 579 WPSRVLRYTFDPSYPDKNKNGIRDFLKTYEKELGNCLKFVEEKNDVFATVVLG--GGCSA 406
WP+ + Y P Y + + +K Y ++ C++FV + + +G GC +
Sbjct: 89 WPNARIPYAISPHYSPHERALLAKAVKQYHEK--TCIRFVPRQTGEPDYLFIGKVDGCFS 146
Query: 405 NVGYNKNYPLKITLPDPCVNKRNVKHEFTHLLGFMHEHTRPDRDNFLKINFENVHSGLCN 226
VG + ++L + C+ + HE H++GF HEH R DRDNF+ I ++N+ G +
Sbjct: 147 EVGRTSGVQV-LSLDNGCMEYATIIHEMMHVVGFYHEHERWDRDNFIDIIWQNIDRGALD 205
Query: 225 NFYLCEGCKLT---TTYDFDSIMQYPSEAFSCNGKDTILKK-NGGKIPFNMEVTKLDAKK 58
F + K + YD+ SI+ Y S AFS NG T+L K I + + +D K
Sbjct: 206 QFGKVDLSKTSYYGQPYDYKSILHYDSLAFSKNGFPTMLPKVKSATIGNARDFSDVDISK 265
Query: 57 VRDYYGC 37
+ Y C
Sbjct: 266 INRMYNC 272
>sp|Q9U3S9|NAS6_CAEEL Zinc metalloproteinase nas-6 precursor (Nematode astacin 6)
Length = 344
Score = 87.4 bits (215), Expect = 4e-17
Identities = 59/198 (29%), Positives = 92/198 (46%), Gaps = 9/198 (4%)
Frame = -2
Query: 603 FRAAQGTQ--WPSRVLRYTFDPSYPDKNKNGIRDFLKTYEKELGNCLKFVEEKNDV-FAT 433
F A + Q W V+ Y D ++ + +Y + C++F + + +
Sbjct: 71 FNALKNKQLTWEGGVIPYEMDTAFSPNEIKILEKAFDSYRRT--TCIRFEKREGQTDYLN 128
Query: 432 VVLGGGCSANVGYNKNYPLKITLPDPCVNKRNVKHEFTHLLGFMHEHTRPDRDNFLKINF 253
+V G GC + VG +I+L C + HE H +GF HEH+R DRD+ +KIN+
Sbjct: 129 IVKGYGCYSQVGRTGGKQ-EISLGRGCFFHEIIVHELMHSVGFWHEHSRADRDDHIKINW 187
Query: 252 ENVHSGLCNNFYLCEGCKLT---TTYDFDSIMQYPSEAFSCNGKDTILKKNGG---KIPF 91
+N+ G+ + F YD+ SIM Y S AFS NG++TI G I
Sbjct: 188 DNILPGMKSQFDKISAVLQDLQGENYDYKSIMHYDSTAFSRNGRNTIETVENGFTQVIGT 247
Query: 90 NMEVTKLDAKKVRDYYGC 37
M+++ LD K+ Y C
Sbjct: 248 AMDLSPLDIVKINKLYSC 265
>sp|P98070|BMP1_XENLA Bone morphogenetic protein 1 precursor (BMP-1)
Length = 707
Score = 86.7 bits (213), Expect = 8e-17
Identities = 63/192 (32%), Positives = 88/192 (45%), Gaps = 11/192 (5%)
Frame = -2
Query: 579 WPSRVLRYTFDPSYPDKNKNGIRDFLKTYEKELGNCLKFVE--EKNDVFATVVLGGGCSA 406
WP V+ Y ++ + R ++ +EK C+ F+E +++ GC +
Sbjct: 93 WPDGVIPYVISGNFSGSQRAIFRQAMRHWEKH--TCVTFLERTDEDSYIVFTYRPCGCCS 150
Query: 405 NVGYNKNYPLKITLPDPCVNKRNVKHEFTHLLGFMHEHTRPDRDNFLKINFENVHSGLCN 226
VG P I++ C V HE H++GF HEHTRPDRD+ + I EN+ G
Sbjct: 151 YVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDDHVSIIRENIQPGQEY 210
Query: 225 NFYLCEGCK---LTTTYDFDSIMQYPSEAFSCN-GKDTILKK---NGGKIPFNM--EVTK 73
NF E + L TYDFDSIM Y FS DTIL K NG + P ++
Sbjct: 211 NFLKMEPEEVESLGETYDFDSIMHYARNTFSRGIFLDTILPKYDVNGVRPPIGQRTRLSS 270
Query: 72 LDAKKVRDYYGC 37
D + R Y C
Sbjct: 271 GDVAQARKLYKC 282
>sp|Q20191|NAS13_CAEEL Zinc metalloproteinase nas-13 precursor (Nematode astacin 13)
Length = 527
Score = 86.7 bits (213), Expect = 8e-17
Identities = 61/189 (32%), Positives = 95/189 (50%), Gaps = 7/189 (3%)
Frame = -2
Query: 582 QWPSRVLRYTFDPSYPDKNKNGIRDFLKTYEKELGNCLKFVEEK-NDV-FATVVLGGGCS 409
+W + YT Y +++ I + ++ Y K+ C+ F + D+ + +V GC
Sbjct: 195 KWEQARIPYTISSQYSSYSRSKIAEAIEEYRKK--TCIDFSPKSAGDLDYIHIVPDDGCY 252
Query: 408 ANVGYNKNYPLKITLPDPCVNKRNVKHEFTHLLGFMHEHTRPDRDNFLKINFENVHSGLC 229
+ VG ++L D C+ K + HE H +GF HE +R DRD ++KIN+ NV +GL
Sbjct: 253 SLVG-RIGGKQPVSLGDGCIQKGIIIHELMHAVGFFHEQSRADRDEYVKINWSNVEAGLQ 311
Query: 228 NNF---YLCEGCKLTTTYDFDSIMQYPSEAFSCNGKDTI--LKKNGGKIPFNMEVTKLDA 64
+ F L L T YD+ S+M Y AFS NGK TI ++KN +I ++ D
Sbjct: 312 DQFDKYSLNMIDHLGTKYDYGSVMHYAPTAFSKNGKPTIEPIEKN-VEIGQRAGFSENDI 370
Query: 63 KKVRDYYGC 37
K+ Y C
Sbjct: 371 YKINMLYNC 379
>sp|P13497|BMP1_HUMAN Bone morphogenetic protein 1 precursor (BMP-1) (Procollagen
C-proteinase) (PCP) (Mammalian tolloid protein) (mTld)
Length = 986
Score = 86.3 bits (212), Expect = 1e-16
Identities = 63/192 (32%), Positives = 88/192 (45%), Gaps = 11/192 (5%)
Frame = -2
Query: 579 WPSRVLRYTFDPSYPDKNKNGIRDFLKTYEKELGNCLKFVE--EKNDVFATVVLGGGCSA 406
WP V+ + ++ + R ++ +EK C+ F+E +++ GC +
Sbjct: 130 WPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKH--TCVTFLERTDEDSYIVFTYRPCGCCS 187
Query: 405 NVGYNKNYPLKITLPDPCVNKRNVKHEFTHLLGFMHEHTRPDRDNFLKINFENVHSGLCN 226
VG P I++ C V HE H++GF HEHTRPDRD + I EN+ G
Sbjct: 188 YVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEY 247
Query: 225 NFYLCEGCK---LTTTYDFDSIMQYPSEAFSCN-GKDTILKK---NGGKIPFNM--EVTK 73
NF E + L TYDFDSIM Y FS DTI+ K NG K P ++K
Sbjct: 248 NFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSK 307
Query: 72 LDAKKVRDYYGC 37
D + R Y C
Sbjct: 308 GDIAQARKLYKC 319
>sp|P42674|BP10_PARLI Blastula protease 10 precursor
Length = 597
Score = 84.0 bits (206), Expect = 5e-16
Identities = 50/172 (29%), Positives = 87/172 (50%), Gaps = 11/172 (6%)
Frame = -2
Query: 591 QGTQWPSRVLRYTFDPSYPDKNKNGIRDFLKTYEKELGNCLKFVEEKN--------DVFA 436
+ +WP +V+ Y PS ++ IR+ + +E+ CL+F + + +
Sbjct: 98 ESQRWPYKVIPYVISPSSSGQSSL-IRNAMDHWEQN--TCLRFEPRTSSHSRQLGHNAYL 154
Query: 435 TVVLGGGCSANVGYNKNYPLKITLPDPCVNKRNVKHEFTHLLGFMHEHTRPDRDNFLKIN 256
+ G GC + VG N +I++ + C + HE H +GF HE +RPDRD+++ +
Sbjct: 155 SFFRGSGCWSYVGKAFNGEQQISIGNGCAYFGTIVHEIGHAIGFHHEQSRPDRDDYINVL 214
Query: 255 FENVHSGLCNNFYLCEGCKLTT---TYDFDSIMQYPSEAFSCNGKDTILKKN 109
++N+ SG +NF ++T+ YD SIM Y FS NG+ TI ++
Sbjct: 215 YQNIQSGRQHNFAKYTWGRVTSRNVEYDVGSIMHYGGYGFSSNGRPTITTRD 266
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 87,909,378
Number of Sequences: 369166
Number of extensions: 1708556
Number of successful extensions: 5003
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4763
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4955
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8293644780
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)