Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_01657 (824 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q9JM53|PDCD8_RAT Programmed cell death protein 8, mitoch... 87 7e-17 sp|Q9Z0X1|PDCD8_MOUSE Programmed cell death protein 8, mito... 87 7e-17 sp|O95831|PDCD8_HUMAN Programmed cell death protein 8, mito... 86 9e-17 sp|Q9VQ79|PDCD8_DROME Putative oxidoreductase CG7263, mitoc... 86 9e-17 sp|O51597|SECF_BORBU Protein-export membrane protein secF 33 0.95 sp|Q9WTV1|CH3L1_RAT Chitinase-3-like protein 1 precursor (C... 32 2.8 sp|P58145|ROAA_ASTLO Ribosomal operon-associated A protein ... 30 6.2 sp|Q02137|ILVB_LACLA Acetolactate synthase large subunit (A... 30 6.2 sp|Q9WZH8|SYC_THEMA Cysteinyl-tRNA synthetase (Cysteine--tR... 30 8.1 sp|Q7VD64|TAL_PROMA Transaldolase 30 8.1
>sp|Q9JM53|PDCD8_RAT Programmed cell death protein 8, mitochondrial precursor (Apoptosis-inducing factor) Length = 612 Score = 86.7 bits (213), Expect = 7e-17 Identities = 69/228 (30%), Positives = 98/228 (42%), Gaps = 19/228 (8%) Frame = +2 Query: 68 FLVNAELLAREGIYVAGDSCSFFDVNLGRRRVEHWNHSEESGSIAGHNMVAYVLKSVDAS 247 F VNAEL AR I+VAGD+ F+D+ LGRRRVEH +H+ SG +AG NM Sbjct: 420 FRVNAELQARSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAA------- 472 Query: 248 YFDSNSPKFVDNSNLIYDIFKPRIYNFQSSFAFKFNIYNSLEAIGLTDSKLET-KTFVAT 424 KP Y QS F EAIGL DS L T F Sbjct: 473 --------------------KP--YWHQSMFWSDLGPDVGYEAIGLVDSSLPTVGVFAKA 510 Query: 425 DFYDDDFNIVESDEKVVEKALKPKTEHDPLDMP------------------GVVFYLKNK 550 D+ + E + + ++E + +P GV+FYL++K Sbjct: 511 TAQDNPKSATEQSGTGIRSESETESEASEITIPPSDPAVPQVPVEGEDYGKGVIFYLRDK 570 Query: 551 EIVGVLLWNVDDDIIIESDFPSPLRINVARKILAQHPKIQSNTDLIKL 694 +VG++LWNV + R+ +ARKI+ + + ++ KL Sbjct: 571 VVVGIVLWNVFN------------RMPIARKIIKDGEQHEDLNEVAKL 606
>sp|Q9Z0X1|PDCD8_MOUSE Programmed cell death protein 8, mitochondrial precursor (Apoptosis-inducing factor) Length = 612 Score = 86.7 bits (213), Expect = 7e-17 Identities = 69/228 (30%), Positives = 98/228 (42%), Gaps = 19/228 (8%) Frame = +2 Query: 68 FLVNAELLAREGIYVAGDSCSFFDVNLGRRRVEHWNHSEESGSIAGHNMVAYVLKSVDAS 247 F VNAEL AR I+VAGD+ F+D+ LGRRRVEH +H+ SG +AG NM Sbjct: 420 FRVNAELQARSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAA------- 472 Query: 248 YFDSNSPKFVDNSNLIYDIFKPRIYNFQSSFAFKFNIYNSLEAIGLTDSKLET-KTFVAT 424 KP Y QS F EAIGL DS L T F Sbjct: 473 --------------------KP--YWHQSMFWSDLGPDVGYEAIGLVDSSLPTVGVFAKA 510 Query: 425 DFYDDDFNIVESDEKVVEKALKPKTEHDPLDMP------------------GVVFYLKNK 550 D+ + E + + ++E + +P GV+FYL++K Sbjct: 511 TAQDNPKSATEQSGTGIRSESETESEASEITIPPSAPAVPQVPVEGEDYGKGVIFYLRDK 570 Query: 551 EIVGVLLWNVDDDIIIESDFPSPLRINVARKILAQHPKIQSNTDLIKL 694 +VG++LWNV + R+ +ARKI+ + + ++ KL Sbjct: 571 VVVGIVLWNVFN------------RMPIARKIIKDGEQHEDLNEVAKL 606
>sp|O95831|PDCD8_HUMAN Programmed cell death protein 8, mitochondrial precursor (Apoptosis-inducing factor) Length = 613 Score = 86.3 bits (212), Expect = 9e-17 Identities = 68/228 (29%), Positives = 98/228 (42%), Gaps = 19/228 (8%) Frame = +2 Query: 68 FLVNAELLAREGIYVAGDSCSFFDVNLGRRRVEHWNHSEESGSIAGHNMVAYVLKSVDAS 247 F VNAEL AR I+VAGD+ F+D+ LGRRRVEH +H+ SG +AG NM Sbjct: 421 FRVNAELQARSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAA------- 473 Query: 248 YFDSNSPKFVDNSNLIYDIFKPRIYNFQSSFAFKFNIYNSLEAIGLTDSKLET-KTFVAT 424 KP Y QS F EAIGL DS L T F Sbjct: 474 --------------------KP--YWHQSMFWSDLGPDVGYEAIGLVDSSLPTVGVFAKA 511 Query: 425 DFYDDDFNIVESDEKVVEKALKPKTEHDPLDMP------------------GVVFYLKNK 550 D+ + E + + ++E + +P GV+FYL++K Sbjct: 512 TAQDNPKSATEQSGTGIRSESETESEASEITIPPSTPAVPQAPVQGEDYGKGVIFYLRDK 571 Query: 551 EIVGVLLWNVDDDIIIESDFPSPLRINVARKILAQHPKIQSNTDLIKL 694 +VG++LWN+ + R+ +ARKI+ + + ++ KL Sbjct: 572 VVVGIVLWNIFN------------RMPIARKIIKDGEQHEDLNEVAKL 607
>sp|Q9VQ79|PDCD8_DROME Putative oxidoreductase CG7263, mitochondrial precursor Length = 739 Score = 86.3 bits (212), Expect = 9e-17 Identities = 72/229 (31%), Positives = 95/229 (41%), Gaps = 20/229 (8%) Frame = +2 Query: 68 FLVNAELLAREGIYVAGDSCSFFDVNLGRRRVEHWNHSEESGSIAGHNMVAYVLKSVDAS 247 F+VNAEL AR +YVAGD+ FFD LGRRRVEH +HS SG +AG NM Sbjct: 547 FVVNAELEARRNLYVAGDASCFFDPLLGRRRVEHHDHSVVSGRLAGENMTG--------- 597 Query: 248 YFDSNSPKFVDNSNLIYDIFKPRIYNFQSSFAFKFNIYNSLEAIGLTDSKLETKTFVA-- 421 + Y QS F E IGL DS L T A Sbjct: 598 --------------------AKKPYQHQSMFWSDLGPEIGYEGIGLVDSSLPTVGVFALP 637 Query: 422 TDFYDDDFNIVESDEKVVEKALKPKTEHDPLDM------------------PGVVFYLKN 547 ++ + ES + V + ++ D GV+FYLKN Sbjct: 638 SESATRVDQLSESSDSDVPETSTSSSQSSKSDAGASQDGVTCDPDEAGNYGKGVIFYLKN 697 Query: 548 KEIVGVLLWNVDDDIIIESDFPSPLRINVARKILAQHPKIQSNTDLIKL 694 +IVG+LLWN+ + RI +AR I+ Q+ K ++ KL Sbjct: 698 DKIVGILLWNLFN------------RIGLARTIINQNKKYDDLNEVAKL 734
>sp|O51597|SECF_BORBU Protein-export membrane protein secF Length = 299 Score = 33.1 bits (74), Expect = 0.95 Identities = 43/159 (27%), Positives = 66/159 (41%), Gaps = 12/159 (7%) Frame = +2 Query: 290 LIYDIFKPRIYNFQSSFAFKFNIYNSLEAIGLTDSKLET------KTFVATDFYDDDFN- 448 LIY F YN+ F+ + NI S+E + +++++ KT + D N Sbjct: 26 LIYTFFYHGGYNWGIDFSSRVNINLSIEKSNIKENEIKKIFSPIYKTLDVNSIFSPDQNK 85 Query: 449 -----IVESDEKVVEKALKPKTEHDPLDMPGVVFYLKNKEIVGVLLWNVDDDIIIESDFP 613 +V+SD V++ A K + + LD K KE + V D I+S F Sbjct: 86 SEFSIMVKSD--VIDYAFKTEVQKTILD--------KLKETFDANI-EVLDSYFIDSSFS 134 Query: 614 SPLRINVARKILAQHPKIQSNTDLIKLASEFDLSFYVNS 730 S LRI +L I LI + F LS+ + S Sbjct: 135 STLRIRSIFLVLGTFILI-----LIYITLRFKLSYAIAS 168
>sp|Q9WTV1|CH3L1_RAT Chitinase-3-like protein 1 precursor (Cartilage glycoprotein 39) (GP-39) Length = 381 Score = 31.6 bits (70), Expect = 2.8 Identities = 13/28 (46%), Positives = 18/28 (64%) Frame = +2 Query: 506 DPLDMPGVVFYLKNKEIVGVLLWNVDDD 589 DP + V YLKNK++ G ++W VD D Sbjct: 328 DPESVKNKVKYLKNKQLAGAMVWAVDLD 355
>sp|P58145|ROAA_ASTLO Ribosomal operon-associated A protein (RoaA) Length = 519 Score = 30.4 bits (67), Expect = 6.2 Identities = 16/55 (29%), Positives = 27/55 (49%) Frame = +2 Query: 284 SNLIYDIFKPRIYNFQSSFAFKFNIYNSLEAIGLTDSKLETKTFVATDFYDDDFN 448 +NL+ + P + +F F FN Y +L I L K+ K F+ ++ +FN Sbjct: 126 NNLVKFVMYPFLELKTENFVFNFNFYTNLYDIFLNFKKILLKNFMKLYYFTINFN 180
>sp|Q02137|ILVB_LACLA Acetolactate synthase large subunit (AHAS) (Acetohydroxy-acid synthase large subunit) (ALS) Length = 575 Score = 30.4 bits (67), Expect = 6.2 Identities = 23/88 (26%), Positives = 43/88 (48%) Frame = +2 Query: 329 QSSFAFKFNIYNSLEAIGLTDSKLETKTFVATDFYDDDFNIVESDEKVVEKALKPKTEHD 508 QS F + N EA G+ KL+ +A DD I+ DE ++ + L K+EH Sbjct: 493 QSVFDVEPNFQLLAEAYGIKHVKLDNPKTLA-----DDLKIITEDEPMLIEVLISKSEH- 546 Query: 509 PLDMPGVVFYLKNKEIVGVLLWNVDDDI 592 +P + L + E++G+ + ++++ Sbjct: 547 --VLPMIPAGLHSDEMIGLHFTDENEEV 572
>sp|Q9WZH8|SYC_THEMA Cysteinyl-tRNA synthetase (Cysteine--tRNA ligase) (CysRS) Length = 460 Score = 30.0 bits (66), Expect = 8.1 Identities = 30/107 (28%), Positives = 47/107 (43%), Gaps = 6/107 (5%) Frame = +2 Query: 359 YNSLEAIGLTDSKLETKTFVATDFYDDDFNIVESDEKVVEKALKPKTEHDPLDMPGVVFY 538 + A+G+ + +T TDF +D IVE EK+VEK +TE GV F Sbjct: 96 WRDAHALGIRPANFHPRT---TDFVED---IVEIIEKLVEKGFAYQTE------TGVYFD 143 Query: 539 LKNKEIVGVLLWNVDDDII------IESDFPSPLRINVARKILAQHP 661 ++ E G L +D+I ++ SPL ++ +K P Sbjct: 144 VRKFEKYGELSKKKIEDLIAGARVEVDETKKSPLDFSLWKKAKPGEP 190
>sp|Q7VD64|TAL_PROMA Transaldolase Length = 335 Score = 30.0 bits (66), Expect = 8.1 Identities = 25/92 (27%), Positives = 45/92 (48%), Gaps = 2/92 (2%) Frame = +2 Query: 440 DFNIVESDEKVVEKALKPKTEHDPLDMPGVVFYLKNKEIVGVLLWNVDDDIIIESDFPSP 619 D ++ S ++V A + + LD V F KEI+ ++ V ++ F + Sbjct: 53 DKSLQASRQRVGSFASAKEVVDEALDEVCVTF---GKEILKIIPGRVSTEVDARLSFNTQ 109 Query: 620 LRINVARKILAQHPKIQSNTD--LIKLASEFD 709 IN ARKI+ + K+ + + LIK+AS ++ Sbjct: 110 ATINKARKIIDLYKKVDISKERVLIKVASTWE 141
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 83,077,498 Number of Sequences: 369166 Number of extensions: 1544153 Number of successful extensions: 4593 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 4299 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4591 length of database: 68,354,980 effective HSP length: 109 effective length of database: 48,218,865 effective search space used: 7956112725 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)