Planaria EST Database


DrC_01653

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_01653
         (653 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q60HG7|CGL_MACFA  Cystathionine gamma-lyase (Gamma-cystat...   183   3e-46
sp|Q8VCN5|CGL_MOUSE  Cystathionine gamma-lyase (Gamma-cystat...   183   4e-46
sp|P18757|CGL_RAT  Cystathionine gamma-lyase (Gamma-cystathi...   181   1e-45
sp|P32929|CGL_HUMAN  Cystathionine gamma-lyase (Gamma-cystat...   179   4e-45
sp|P55216|CGL_CAEEL  Putative cystathionine gamma-lyase (Gam...   177   3e-44
sp|P66876|METB_MYCBO  Cystathionine gamma-synthase (CGS) (O-...   150   2e-36
sp|P56069|METB_HELPY  Cystathionine gamma-synthase (CGS) (O-...   147   2e-35
sp|P46807|METB_MYCLE  Cystathionine gamma-synthase (CGS) (O-...   145   1e-34
sp|Q9ZMW7|METB_HELPJ  Cystathionine gamma-synthase (CGS) (O-...   141   1e-33
sp|P0A4K3|METC_LACLC  Cystathionine beta-lyase (CBL) (Beta-c...   136   4e-32
>sp|Q60HG7|CGL_MACFA Cystathionine gamma-lyase (Gamma-cystathionase)
          Length = 405

 Score =  183 bits (465), Expect = 3e-46
 Identities = 95/177 (53%), Positives = 125/177 (70%)
 Frame = +2

Query: 2   SDVLMGAAAMNNEGLYESLRQQQLMVGAVPSPFDCYLALRGLRTLVVRMTQHQLNGLAVA 181
           SDV+MG  ++N E L+  LR  Q  +GAVPSP DCYL  RGL+TL VRM +H  NG+AVA
Sbjct: 218 SDVVMGLVSVNCERLHNRLRFLQNSLGAVPSPLDCYLCNRGLKTLHVRMEKHFKNGMAVA 277

Query: 182 LFLADHPKIEKVLHPALFPSPQKEIIAKQMTGFSGMLSAYVKGSHEDIVDFMKNLKYFPI 361
            FL  +P +EKV++P L   PQ E+  +Q TG +GM++ Y+KG+ +    F+KNLK F +
Sbjct: 278 QFLESNPGVEKVIYPGLPSHPQHELAKRQCTGCTGMITFYIKGTLQHAEIFLKNLKLFTL 337

Query: 362 AKSLGGFESLIEIPSLMTYTSVPLDKCVELGICDNLVRFSVGLEDIYSLLEDLDNGL 532
           A+SLGGFESL+E+P++MT+ SVP +    LGI D L+R SVGLED   LLEDLD  L
Sbjct: 338 AESLGGFESLVELPAIMTHASVPKNDRDVLGISDTLIRLSVGLEDEKDLLEDLDQAL 394
>sp|Q8VCN5|CGL_MOUSE Cystathionine gamma-lyase (Gamma-cystathionase)
          Length = 398

 Score =  183 bits (464), Expect = 4e-46
 Identities = 94/177 (53%), Positives = 124/177 (70%)
 Frame = +2

Query: 2   SDVLMGAAAMNNEGLYESLRQQQLMVGAVPSPFDCYLALRGLRTLVVRMTQHQLNGLAVA 181
           SDV+MG  ++N++ L   LR  Q  +GAVPSPFDCYL  RGL+TL VRM +H  NG+AVA
Sbjct: 217 SDVVMGLVSVNSDDLNSRLRFLQNSLGAVPSPFDCYLCCRGLKTLQVRMEKHFKNGMAVA 276

Query: 182 LFLADHPKIEKVLHPALFPSPQKEIIAKQMTGFSGMLSAYVKGSHEDIVDFMKNLKYFPI 361
            FL  +P++EKV++P L   PQ E+  +Q +G  GM+S Y+KG+ +    F+KNLK F +
Sbjct: 277 RFLETNPRVEKVVYPGLPSHPQHELAKRQCSGCPGMVSFYIKGALQHAKAFLKNLKLFTL 336

Query: 362 AKSLGGFESLIEIPSLMTYTSVPLDKCVELGICDNLVRFSVGLEDIYSLLEDLDNGL 532
           A+SLGG+ESL E+P++MT+ SVP      LGI D L+R SVGLED   LLEDLD  L
Sbjct: 337 AESLGGYESLAELPAIMTHASVPEKDRATLGINDTLIRLSVGLEDEQDLLEDLDRAL 393
>sp|P18757|CGL_RAT Cystathionine gamma-lyase (Gamma-cystathionase) (Probasin-related
           antigen) (PRB-RA)
          Length = 398

 Score =  181 bits (459), Expect = 1e-45
 Identities = 92/177 (51%), Positives = 123/177 (69%)
 Frame = +2

Query: 2   SDVLMGAAAMNNEGLYESLRQQQLMVGAVPSPFDCYLALRGLRTLVVRMTQHQLNGLAVA 181
           SDV+MG  ++ ++ L E LR  Q  +GAVPSPFDCYL  RGL+TL +RM +H  NG+AVA
Sbjct: 217 SDVVMGLVSVTSDDLNERLRFLQNSLGAVPSPFDCYLCCRGLKTLQIRMEKHFRNGMAVA 276

Query: 182 LFLADHPKIEKVLHPALFPSPQKEIIAKQMTGFSGMLSAYVKGSHEDIVDFMKNLKYFPI 361
            FL  +P++EKV++P L   PQ E+  +Q TG  GM+S Y+KG+ +    F+KN+K F +
Sbjct: 277 RFLESNPRVEKVIYPGLPSHPQHELAKRQCTGCPGMVSFYIKGTLQHAQVFLKNIKLFAL 336

Query: 362 AKSLGGFESLIEIPSLMTYTSVPLDKCVELGICDNLVRFSVGLEDIYSLLEDLDNGL 532
           A+SLGG+ESL E+P++MT+ SVP      LGI D L+R SVGLED   LLEDL   L
Sbjct: 337 AESLGGYESLAELPAIMTHASVPEKDRATLGISDTLIRLSVGLEDEKDLLEDLGQAL 393
>sp|P32929|CGL_HUMAN Cystathionine gamma-lyase (Gamma-cystathionase)
          Length = 405

 Score =  179 bits (455), Expect = 4e-45
 Identities = 94/177 (53%), Positives = 124/177 (70%)
 Frame = +2

Query: 2   SDVLMGAAAMNNEGLYESLRQQQLMVGAVPSPFDCYLALRGLRTLVVRMTQHQLNGLAVA 181
           SDV+MG  ++N E L+  LR  Q  +GAVPSP DCYL  RGL+TL VRM +H  NG+AVA
Sbjct: 218 SDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVA 277

Query: 182 LFLADHPKIEKVLHPALFPSPQKEIIAKQMTGFSGMLSAYVKGSHEDIVDFMKNLKYFPI 361
            FL  +P +EKV++P L   PQ E++ +Q TG +GM++ Y+KG+ +    F+KNLK F +
Sbjct: 278 QFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTL 337

Query: 362 AKSLGGFESLIEIPSLMTYTSVPLDKCVELGICDNLVRFSVGLEDIYSLLEDLDNGL 532
           A+SLGGFESL E+P++MT+ SV  +    LGI D L+R SVGLED   LLEDLD  L
Sbjct: 338 AESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQAL 394
>sp|P55216|CGL_CAEEL Putative cystathionine gamma-lyase (Gamma-cystathionase)
          Length = 392

 Score =  177 bits (448), Expect = 3e-44
 Identities = 92/177 (51%), Positives = 121/177 (68%)
 Frame = +2

Query: 2   SDVLMGAAAMNNEGLYESLRQQQLMVGAVPSPFDCYLALRGLRTLVVRMTQHQLNGLAVA 181
           SDV+MGA   +N+   + L   QL VGAVPSPFDC+L  RGL+TL +RM  H  N LAVA
Sbjct: 209 SDVVMGAVITDNDEFQQHLFFMQLAVGAVPSPFDCFLVNRGLKTLHIRMRAHYENALAVA 268

Query: 182 LFLADHPKIEKVLHPALFPSPQKEIIAKQMTGFSGMLSAYVKGSHEDIVDFMKNLKYFPI 361
            +L  + +IE VL+PAL   PQ E+  KQ  G SGM+S Y+KG  ++   F+  LK F +
Sbjct: 269 KYLEANDRIESVLYPALPSHPQHEVHEKQTKGMSGMISFYLKGELQESRAFLSALKVFTL 328

Query: 362 AKSLGGFESLIEIPSLMTYTSVPLDKCVELGICDNLVRFSVGLEDIYSLLEDLDNGL 532
           A+SLGG+ESL E+PS+MT+ SVP +  + LGI DNL+R SVG+ED+  L+ DLD  L
Sbjct: 329 AESLGGYESLAELPSIMTHASVPAETRIVLGITDNLIRISVGIEDLDDLVADLDQAL 385
>sp|P66876|METB_MYCBO Cystathionine gamma-synthase (CGS) (O-succinylhomoserine
           (Thiol)-lyase)
 sp|P66875|METB_MYCTU Cystathionine gamma-synthase (CGS) (O-succinylhomoserine
           (Thiol)-lyase)
          Length = 388

 Score =  150 bits (380), Expect = 2e-36
 Identities = 86/177 (48%), Positives = 107/177 (60%)
 Frame = +2

Query: 2   SDVLMGAAAMNNEGLYESLRQQQLMVGAVPSPFDCYLALRGLRTLVVRMTQHQLNGLAVA 181
           SDV+ GA   N+E L E     Q   GAVP PFD YL +RGL+TLV+RM +H  N  AVA
Sbjct: 214 SDVVGGALVTNDEELDEEFAFLQNGAGAVPGPFDAYLTMRGLKTLVLRMQRHSENACAVA 273

Query: 182 LFLADHPKIEKVLHPALFPSPQKEIIAKQMTGFSGMLSAYVKGSHEDIVDFMKNLKYFPI 361
            FLADHP +  VL+P L   P  EI A+QM GF GM+S  ++       D     + F +
Sbjct: 274 EFLADHPSVSSVLYPGLPSHPGHEIAARQMRGFGGMVSVRMRAGRRAAQDLCAKTRVFIL 333

Query: 362 AKSLGGFESLIEIPSLMTYTSVPLDKCVELGICDNLVRFSVGLEDIYSLLEDLDNGL 532
           A+SLGG ESLIE PS MT+ S       +L + D+LVR SVG+EDI  LL DL+  L
Sbjct: 334 AESLGGVESLIEHPSAMTHASTAGS---QLEVPDDLVRLSVGIEDIADLLGDLEQAL 387
>sp|P56069|METB_HELPY Cystathionine gamma-synthase (CGS) (O-succinylhomoserine
           (Thiol)-lyase)
          Length = 380

 Score =  147 bits (371), Expect = 2e-35
 Identities = 83/180 (46%), Positives = 108/180 (60%)
 Frame = +2

Query: 2   SDVLMGAAAMNNEGLYESLRQQQLMVGAVPSPFDCYLALRGLRTLVVRMTQHQLNGLAVA 181
           SDV+ G    NNE L + +   Q  +G V  P D +L  RG++TL +RM  HQ N L VA
Sbjct: 201 SDVVAGLVTTNNEALAQEIAFFQNAIGGVLGPQDSWLLQRGIKTLGLRMEAHQKNALCVA 260

Query: 182 LFLADHPKIEKVLHPALFPSPQKEIIAKQMTGFSGMLSAYVKGSHEDIVDFMKNLKYFPI 361
            FL  HPK+E+V +P L   P  E+  KQM GFSGMLS  +K   E  V F+++LK F +
Sbjct: 261 EFLEKHPKVERVYYPGLPTHPNYELAKKQMRGFSGMLSFTLKNDSE-AVAFVESLKLFIL 319

Query: 362 AKSLGGFESLIEIPSLMTYTSVPLDKCVELGICDNLVRFSVGLEDIYSLLEDLDNGLTKI 541
            +SLGG ESL+ IP+ MT+  +P  +    GI D LVR SVG+E    LLEDL+    KI
Sbjct: 320 GESLGGVESLVGIPAFMTHACIPKTQREAAGIRDGLVRLSVGIEHEQDLLEDLEQAFAKI 379
>sp|P46807|METB_MYCLE Cystathionine gamma-synthase (CGS) (O-succinylhomoserine
           (Thiol)-lyase)
          Length = 388

 Score =  145 bits (365), Expect = 1e-34
 Identities = 83/177 (46%), Positives = 107/177 (60%)
 Frame = +2

Query: 2   SDVLMGAAAMNNEGLYESLRQQQLMVGAVPSPFDCYLALRGLRTLVVRMTQHQLNGLAVA 181
           SDV+ GA   N+E L ++    Q   GAVPSPFD YL +RGL+TLV+RM +H  N + VA
Sbjct: 214 SDVVGGALVTNDEELDQAFGFLQNGAGAVPSPFDAYLTMRGLKTLVLRMQRHNENAITVA 273

Query: 182 LFLADHPKIEKVLHPALFPSPQKEIIAKQMTGFSGMLSAYVKGSHEDIVDFMKNLKYFPI 361
            FLA HP +  VL+P L   P  E+ A+QM GF GM+S  ++       D     K F +
Sbjct: 274 EFLAGHPSVSAVLYPGLPSHPGHEVAARQMRGFGGMVSLRMRAGRLAAQDLCARTKVFTL 333

Query: 362 AKSLGGFESLIEIPSLMTYTSVPLDKCVELGICDNLVRFSVGLEDIYSLLEDLDNGL 532
           A+SLGG ESLIE PS MT+ S       +L + D+LVR SVG+ED+  LL DL   L
Sbjct: 334 AESLGGVESLIEQPSAMTHASTTGS---QLEVPDDLVRLSVGIEDVGDLLCDLKQAL 387
>sp|Q9ZMW7|METB_HELPJ Cystathionine gamma-synthase (CGS) (O-succinylhomoserine
           (Thiol)-lyase)
          Length = 380

 Score =  141 bits (356), Expect = 1e-33
 Identities = 82/180 (45%), Positives = 105/180 (58%)
 Frame = +2

Query: 2   SDVLMGAAAMNNEGLYESLRQQQLMVGAVPSPFDCYLALRGLRTLVVRMTQHQLNGLAVA 181
           SDV+ G    NNE L +     Q  +G V    D +L  RG++TL +RM  HQ N L VA
Sbjct: 201 SDVVAGLVTTNNEALAQEFDFFQNAIGGVLGLQDSWLLQRGIKTLGLRMEAHQKNALCVA 260

Query: 182 LFLADHPKIEKVLHPALFPSPQKEIIAKQMTGFSGMLSAYVKGSHEDIVDFMKNLKYFPI 361
            FL  HPK+E+V +P L   P  E+   QM GFSGM S  +K   E  V F+++LK F +
Sbjct: 261 EFLEKHPKVERVYYPGLPTHPNHELAKAQMRGFSGMFSFTLKNDSE-AVAFVESLKLFIL 319

Query: 362 AKSLGGFESLIEIPSLMTYTSVPLDKCVELGICDNLVRFSVGLEDIYSLLEDLDNGLTKI 541
            +SLGG ESL+ IP+LMT+  +P  +    GI D LVR SVG+E    LLEDLD    KI
Sbjct: 320 GESLGGVESLVGIPALMTHACIPKAQREAAGIRDGLVRLSVGIEHEQDLLEDLDQAFAKI 379
>sp|P0A4K3|METC_LACLC Cystathionine beta-lyase (CBL) (Beta-cystathionase) (Cysteine
           lyase)
 sp|P0A4K2|METC_LACLA Cystathionine beta-lyase (CBL) (Beta-cystathionase) (Cysteine
           lyase)
          Length = 380

 Score =  136 bits (343), Expect = 4e-32
 Identities = 75/179 (41%), Positives = 106/179 (59%)
 Frame = +2

Query: 2   SDVLMGAAAMNNEGLYESLRQQQLMVGAVPSPFDCYLALRGLRTLVVRMTQHQLNGLAVA 181
           SDV+ G    N++ L   +   Q  +GAV  P D +L  RG++TL +RM  H  N   +A
Sbjct: 202 SDVVAGLVTTNSKELASEIGFLQNSIGAVLGPQDSWLVQRGIKTLALRMEAHSANAQKIA 261

Query: 182 LFLADHPKIEKVLHPALFPSPQKEIIAKQMTGFSGMLSAYVKGSHEDIVDFMKNLKYFPI 361
            FL     + KV +P L   P  EI  KQM+ F GM+S  +   +  + DF++NL YF +
Sbjct: 262 EFLETSKAVSKVYYPGLNSHPGHEIAKKQMSAFGGMISFELTDENA-VKDFVENLSYFTL 320

Query: 362 AKSLGGFESLIEIPSLMTYTSVPLDKCVELGICDNLVRFSVGLEDIYSLLEDLDNGLTK 538
           A+SLGG ESLIE+P++MT+ S+P +   E+GI D L+R SVG+E I  LL D+   L K
Sbjct: 321 AESLGGVESLIEVPAVMTHASIPKELREEIGIKDGLIRLSVGVEAIEDLLTDIKEALEK 379
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 71,720,624
Number of Sequences: 369166
Number of extensions: 1387752
Number of successful extensions: 3406
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3307
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3383
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5413810770
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)