Planaria EST Database


DrC_01648

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_01648
         (809 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|P29678|MP2K1_RABIT  Dual specificity mitogen-activated pr...   207   3e-53
sp|Q01986|MP2K1_RAT  Dual specificity mitogen-activated prot...   207   4e-53
sp|Q02750|MP2K1_HUMAN  Dual specificity mitogen-activated pr...   207   4e-53
sp|P31938|MP2K1_MOUSE  Dual specificity mitogen-activated pr...   206   5e-53
sp|P36506|MP2K2_RAT  Dual specificity mitogen-activated prot...   206   8e-53
sp|Q63932|MP2K2_MOUSE  Dual specificity mitogen-activated pr...   206   8e-53
sp|Q63980|MP2K1_CRIGR  Dual specificity mitogen-activated pr...   204   2e-52
sp|Q90891|MP2K2_CHICK  Dual specificity mitogen-activated pr...   204   2e-52
sp|Q90321|MP2K2_CYPCA  Dual specificity mitogen-activated pr...   203   4e-52
sp|P36507|MP2K2_HUMAN  Dual specificity mitogen-activated pr...   203   5e-52
>sp|P29678|MP2K1_RABIT Dual specificity mitogen-activated protein kinase kinase 1 (MAP
           kinase kinase 1) (MAPKK 1) (ERK activator kinase 1)
           (MAPK/ERK kinase 1) (MEK1)
          Length = 393

 Score =  207 bits (527), Expect = 3e-53
 Identities = 106/197 (53%), Positives = 139/197 (70%), Gaps = 1/197 (0%)
 Frame = +1

Query: 1   ITISVVNGLLYLREELDIIHRDVKPSNILVNSDGEVKLCDFGVSGQLIDSMANSFVGTRS 180
           ++I+V+ GL YLRE+  I+HRDVKPSNILVNS GE+KLCDFGVSGQLIDSMANSFVGTRS
Sbjct: 169 VSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRS 228

Query: 181 YMAPERLIGEEYNVRSDVWSLGLSLIELATGRYPIPPAKEEDFHSTFSQDRQVNLAEHLD 360
           YM+PERL G  Y+V+SD+WS+GLSL+E+A GRYPIPP   ++    F    + + AE   
Sbjct: 229 YMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQVEGDAAETPP 288

Query: 361 -AALHGKKLKAMQVSDSNNMAIFELLAYIVDYPPPRVPEFCFSNDFITFVHSCLQENASD 537
                G+ L +  +     MAIFELL YIV+ PPP++P   FS +F  FV+ CL +N ++
Sbjct: 289 RPRTPGRPLSSYGMDSRPPMAIFELLDYIVNEPPPKLPSAVFSLEFQDFVNKCLIKNPAE 348

Query: 538 RPRLESLLTYNFLLNPD 588
           R  L+ L+ + F+   D
Sbjct: 349 RADLKQLMVHAFIKRSD 365
>sp|Q01986|MP2K1_RAT Dual specificity mitogen-activated protein kinase kinase 1 (MAP
           kinase kinase 1) (MAPKK 1) (ERK activator kinase 1)
           (MAPK/ERK kinase 1) (MEK1)
          Length = 393

 Score =  207 bits (526), Expect = 4e-53
 Identities = 106/197 (53%), Positives = 139/197 (70%), Gaps = 1/197 (0%)
 Frame = +1

Query: 1   ITISVVNGLLYLREELDIIHRDVKPSNILVNSDGEVKLCDFGVSGQLIDSMANSFVGTRS 180
           ++I+V+ GL YLRE+  I+HRDVKPSNILVNS GE+KLCDFGVSGQLIDSMANSFVGTRS
Sbjct: 169 VSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRS 228

Query: 181 YMAPERLIGEEYNVRSDVWSLGLSLIELATGRYPIPPAKEEDFHSTFSQDRQVNLAEHLD 360
           YM+PERL G  Y+V+SD+WS+GLSL+E+A GRYPIPP   ++    F    + + AE   
Sbjct: 229 YMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELLFGCQVEGDAAETPP 288

Query: 361 -AALHGKKLKAMQVSDSNNMAIFELLAYIVDYPPPRVPEFCFSNDFITFVHSCLQENASD 537
                G+ L +  +     MAIFELL YIV+ PPP++P   FS +F  FV+ CL +N ++
Sbjct: 289 RPRTPGRPLSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAE 348

Query: 538 RPRLESLLTYNFLLNPD 588
           R  L+ L+ + F+   D
Sbjct: 349 RADLKQLMVHAFIKRSD 365
>sp|Q02750|MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 (MAP
           kinase kinase 1) (MAPKK 1) (ERK activator kinase 1)
           (MAPK/ERK kinase 1) (MEK1)
          Length = 393

 Score =  207 bits (526), Expect = 4e-53
 Identities = 106/197 (53%), Positives = 139/197 (70%), Gaps = 1/197 (0%)
 Frame = +1

Query: 1   ITISVVNGLLYLREELDIIHRDVKPSNILVNSDGEVKLCDFGVSGQLIDSMANSFVGTRS 180
           ++I+V+ GL YLRE+  I+HRDVKPSNILVNS GE+KLCDFGVSGQLIDSMANSFVGTRS
Sbjct: 169 VSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRS 228

Query: 181 YMAPERLIGEEYNVRSDVWSLGLSLIELATGRYPIPPAKEEDFHSTFSQDRQVNLAEHLD 360
           YM+PERL G  Y+V+SD+WS+GLSL+E+A GRYPIPP   ++    F    + + AE   
Sbjct: 229 YMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQVEGDAAETPP 288

Query: 361 -AALHGKKLKAMQVSDSNNMAIFELLAYIVDYPPPRVPEFCFSNDFITFVHSCLQENASD 537
                G+ L +  +     MAIFELL YIV+ PPP++P   FS +F  FV+ CL +N ++
Sbjct: 289 RPRTPGRPLSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAE 348

Query: 538 RPRLESLLTYNFLLNPD 588
           R  L+ L+ + F+   D
Sbjct: 349 RADLKQLMVHAFIKRSD 365
>sp|P31938|MP2K1_MOUSE Dual specificity mitogen-activated protein kinase kinase 1 (MAP
           kinase kinase 1) (MAPKK 1) (ERK activator kinase 1)
           (MAPK/ERK kinase 1) (MEK1)
          Length = 393

 Score =  206 bits (525), Expect = 5e-53
 Identities = 106/197 (53%), Positives = 139/197 (70%), Gaps = 1/197 (0%)
 Frame = +1

Query: 1   ITISVVNGLLYLREELDIIHRDVKPSNILVNSDGEVKLCDFGVSGQLIDSMANSFVGTRS 180
           ++I+V+ GL YLRE+  I+HRDVKPSNILVNS GE+KLCDFGVSGQLIDSMANSFVGTRS
Sbjct: 169 VSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRS 228

Query: 181 YMAPERLIGEEYNVRSDVWSLGLSLIELATGRYPIPPAKEEDFHSTFSQDRQVNLAEHLD 360
           YM+PERL G  Y+V+SD+WS+GLSL+E+A GRYPIPP   ++    F    + + AE   
Sbjct: 229 YMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELLFGCHVEGDAAETPP 288

Query: 361 -AALHGKKLKAMQVSDSNNMAIFELLAYIVDYPPPRVPEFCFSNDFITFVHSCLQENASD 537
                G+ L +  +     MAIFELL YIV+ PPP++P   FS +F  FV+ CL +N ++
Sbjct: 289 RPRTPGRPLSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAE 348

Query: 538 RPRLESLLTYNFLLNPD 588
           R  L+ L+ + F+   D
Sbjct: 349 RADLKQLMVHAFIKRSD 365
>sp|P36506|MP2K2_RAT Dual specificity mitogen-activated protein kinase kinase 2 (MAP
           kinase kinase 2) (MAPKK 2) (ERK activator kinase 2)
           (MAPK/ERK kinase 2) (MEK2)
          Length = 400

 Score =  206 bits (523), Expect = 8e-53
 Identities = 106/201 (52%), Positives = 140/201 (69%), Gaps = 9/201 (4%)
 Frame = +1

Query: 1   ITISVVNGLLYLREELDIIHRDVKPSNILVNSDGEVKLCDFGVSGQLIDSMANSFVGTRS 180
           ++I+V+ GL YLRE+  I+HRDVKPSNILVNS GE+KLCDFGVSGQLIDSMANSFVGTRS
Sbjct: 173 VSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRS 232

Query: 181 YMAPERLIGEEYNVRSDVWSLGLSLIELATGRYPIPPAKEEDFHSTFSQDRQVNLAEHLD 360
           YM+PERL G  Y+V+SD+WS+GLSL+ELA GRYPIPP   ++  ++F +     + +  D
Sbjct: 233 YMSPERLQGTHYSVQSDIWSMGLSLVELAIGRYPIPPPDAKELEASFGRP----VVDGAD 288

Query: 361 AALH---------GKKLKAMQVSDSNNMAIFELLAYIVDYPPPRVPEFCFSNDFITFVHS 513
              H         G+ +    +     MAIFELL YIV+ PPP++P   FS+DF  FV+ 
Sbjct: 289 GEPHSVSPRPRPPGRPISGHGMDSRPAMAIFELLDYIVNEPPPKLPSGVFSSDFQEFVNK 348

Query: 514 CLQENASDRPRLESLLTYNFL 576
           CL +N ++R  L+ L  + F+
Sbjct: 349 CLIKNPAERADLKLLTNHAFI 369
>sp|Q63932|MP2K2_MOUSE Dual specificity mitogen-activated protein kinase kinase 2 (MAP
           kinase kinase 2) (MAPKK 2) (ERK activator kinase 2)
           (MAPK/ERK kinase 2) (MEK2)
          Length = 401

 Score =  206 bits (523), Expect = 8e-53
 Identities = 108/202 (53%), Positives = 142/202 (70%), Gaps = 10/202 (4%)
 Frame = +1

Query: 1   ITISVVNGLLYLREELDIIHRDVKPSNILVNSDGEVKLCDFGVSGQLIDSMANSFVGTRS 180
           ++I+V+ GL YLRE+  I+HRDVKPSNILVNS GE+KLCDFGVSGQLIDSMANSFVGTRS
Sbjct: 173 VSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRS 232

Query: 181 YMAPERLIGEEYNVRSDVWSLGLSLIELATGRYPIPPAKEEDFHSTFSQDRQVNLAEHLD 360
           YM+PERL G  Y+V+SD+WS+GLSL+ELA GRYPIPP   ++  ++F +     + +  D
Sbjct: 233 YMSPERLQGTHYSVQSDIWSMGLSLVELAIGRYPIPPPDAKELEASFGRP----VVDGAD 288

Query: 361 AALH---------GKKLKAMQVSDSN-NMAIFELLAYIVDYPPPRVPEFCFSNDFITFVH 510
              H         G+ +      DS   MAIFELL YIV+ PPP++P   FS+DF  FV+
Sbjct: 289 GEPHSVSPRPRPPGRPISVGHGMDSRPAMAIFELLDYIVNEPPPKLPSGVFSSDFQEFVN 348

Query: 511 SCLQENASDRPRLESLLTYNFL 576
            CL +N ++R  L+ L+ + F+
Sbjct: 349 KCLIKNPAERADLKLLMNHAFI 370
>sp|Q63980|MP2K1_CRIGR Dual specificity mitogen-activated protein kinase kinase 1 (MAP
           kinase kinase 1) (MAPKK 1) (ERK activator kinase 1)
           (MAPK/ERK kinase 1) (MEK1)
          Length = 393

 Score =  204 bits (520), Expect = 2e-52
 Identities = 106/197 (53%), Positives = 138/197 (70%), Gaps = 1/197 (0%)
 Frame = +1

Query: 1   ITISVVNGLLYLREELDIIHRDVKPSNILVNSDGEVKLCDFGVSGQLIDSMANSFVGTRS 180
           ++I+V+ GL YLRE+  I+HRDVKPSNILVNS GE+KLCDFGVSGQLIDSMANSFVGTRS
Sbjct: 169 VSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRS 228

Query: 181 YMAPERLIGEEYNVRSDVWSLGLSLIELATGRYPIPPAKEEDFHSTFSQDRQVNLAEHLD 360
           YM+PERL G  Y+V+SD+WS+GLSL+E+A GRYPIPP   ++    F    + + AE   
Sbjct: 229 YMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELLFGCQVEGDAAETPP 288

Query: 361 -AALHGKKLKAMQVSDSNNMAIFELLAYIVDYPPPRVPEFCFSNDFITFVHSCLQENASD 537
                G+ L +  +     MAIFELL YIV+ PP ++P   FS +F  FV+ CL +N ++
Sbjct: 289 RPRTPGRPLSSYGMDSRPPMAIFELLDYIVNEPPAKLPSGVFSLEFQDFVNKCLIKNPAE 348

Query: 538 RPRLESLLTYNFLLNPD 588
           R  L+ LL + F+   D
Sbjct: 349 RADLKQLLVHAFIKRSD 365
>sp|Q90891|MP2K2_CHICK Dual specificity mitogen-activated protein kinase kinase 2 (MAP
           kinase kinase 2) (MAPKK 2) (ERK activator kinase 2)
           (MAPK/ERK kinase 2) (MEK2)
          Length = 398

 Score =  204 bits (519), Expect = 2e-52
 Identities = 105/198 (53%), Positives = 141/198 (71%), Gaps = 6/198 (3%)
 Frame = +1

Query: 1   ITISVVNGLLYLREELDIIHRDVKPSNILVNSDGEVKLCDFGVSGQLIDSMANSFVGTRS 180
           ++I+V+ GL YLRE+  I+HRDVKPSNILVNS GE+KLCDFGVSGQLIDSMANSFVGTRS
Sbjct: 171 VSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRS 230

Query: 181 YMAPERLIGEEYNVRSDVWSLGLSLIELATGRYPIPPAKEEDFHSTFSQDRQVNLAEHLD 360
           YM+PERL G  Y+V+SD+WS+GLSL+EL+ GRYPIPP   ++  + F +   V+ AE   
Sbjct: 231 YMSPERLQGTHYSVQSDIWSMGLSLVELSIGRYPIPPPDSKELEAIFGRP-VVDGAEGES 289

Query: 361 AALH------GKKLKAMQVSDSNNMAIFELLAYIVDYPPPRVPEFCFSNDFITFVHSCLQ 522
            ++       G+ +    +     MAIFELL YIV+ PPP++P   F+ DF  FV+ CL 
Sbjct: 290 HSVSPWARPPGRPISGHGMDSRPAMAIFELLDYIVNEPPPKLPNGVFTQDFQEFVNKCLI 349

Query: 523 ENASDRPRLESLLTYNFL 576
           +N ++R  L+ L+ + F+
Sbjct: 350 KNPAERADLKMLMNHTFI 367
>sp|Q90321|MP2K2_CYPCA Dual specificity mitogen-activated protein kinase kinase 2 (MAP
           kinase kinase 2) (MAPKK 2) (ERK activator kinase 2)
           (MAPK/ERK kinase 2) (MEK2)
          Length = 397

 Score =  203 bits (517), Expect = 4e-52
 Identities = 105/197 (53%), Positives = 138/197 (70%), Gaps = 5/197 (2%)
 Frame = +1

Query: 1   ITISVVNGLLYLREELDIIHRDVKPSNILVNSDGEVKLCDFGVSGQLIDSMANSFVGTRS 180
           ++I+V+ GL+YLRE+  I+HRDVKPSNILVNS GE+KLCDFGVSGQLIDSMANSFVGTRS
Sbjct: 170 VSIAVLRGLVYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRS 229

Query: 181 YMAPERLIGEEYNVRSDVWSLGLSLIELATGRYPIPPAKEEDFHSTFSQ---DRQVNLAE 351
           YM+PERL G  Y+V+SDVWS+GLSL+ELA GR+PIPP   ++  + F +   D+      
Sbjct: 230 YMSPERLQGTHYSVQSDVWSMGLSLVELAIGRFPIPPPDAKELEAIFGRPVLDKGGAEGH 289

Query: 352 HLDAALH--GKKLKAMQVSDSNNMAIFELLAYIVDYPPPRVPEFCFSNDFITFVHSCLQE 525
            +       G+ +    +     MAIFELL YIV+ PPP++P   F+ DF  FV  CL +
Sbjct: 290 SMSPRQRPPGRPVSGHGMDSRPAMAIFELLDYIVNEPPPKLPHGVFTTDFEEFVMKCLMK 349

Query: 526 NASDRPRLESLLTYNFL 576
           N +DR  L+ L+ + F+
Sbjct: 350 NPADRADLKMLMGHTFI 366
>sp|P36507|MP2K2_HUMAN Dual specificity mitogen-activated protein kinase kinase 2 (MAP
           kinase kinase 2) (MAPKK 2) (ERK activator kinase 2)
           (MAPK/ERK kinase 2) (MEK2)
          Length = 400

 Score =  203 bits (516), Expect = 5e-52
 Identities = 105/197 (53%), Positives = 137/197 (69%), Gaps = 5/197 (2%)
 Frame = +1

Query: 1   ITISVVNGLLYLREELDIIHRDVKPSNILVNSDGEVKLCDFGVSGQLIDSMANSFVGTRS 180
           ++I+V+ GL YLRE+  I+HRDVKPSNILVNS GE+KLCDFGVSGQLIDSMANSFVGTRS
Sbjct: 173 VSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRS 232

Query: 181 YMAPERLIGEEYNVRSDVWSLGLSLIELATGRYPIPPAKEEDFHSTFSQ---DRQVNLAE 351
           YMAPERL G  Y+V+SD+WS+GLSL+ELA GRYPIPP   ++  + F +   D +     
Sbjct: 233 YMAPERLQGTHYSVQSDIWSMGLSLVELAVGRYPIPPPDAKELEAIFGRPVVDGEEGEPH 292

Query: 352 HLDAALH--GKKLKAMQVSDSNNMAIFELLAYIVDYPPPRVPEFCFSNDFITFVHSCLQE 525
            +       G+ +    +     MAIFELL YIV+ PPP++P   F+ DF  FV+ CL +
Sbjct: 293 SISPRPRPPGRPVSGHGMDSRPAMAIFELLDYIVNEPPPKLPNGVFTPDFQEFVNKCLIK 352

Query: 526 NASDRPRLESLLTYNFL 576
           N ++R  L+ L  + F+
Sbjct: 353 NPAERADLKMLTNHTFI 369
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 88,104,899
Number of Sequences: 369166
Number of extensions: 1719593
Number of successful extensions: 7890
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5975
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6350
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7715018400
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)