Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_01637 (808 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|O00291|HIP1_HUMAN Huntingtin interacting protein 1 (HIP-I) 87 4e-17 sp|Q02328|SLAP2_CAEEL Protein SLA2 homolog 72 1e-12 sp|O75146|HIP1R_HUMAN Huntingtin-interacting protein 1-rela... 71 4e-12 sp|Q9JKY5|HIP1R_MOUSE Huntingtin interacting protein 1 rela... 70 9e-12 sp|Q9P6L5|SLA2_SCHPO Endocytosis protein end4 (SLA2 protein... 54 7e-07 sp|P33338|SLA2_YEAST Protein SLA2 (Transmembrane protein MOP2) 35 0.18 sp|Q10432|YQ37_SCHPO Hypothetical protein C188.07 in chromo... 32 1.6 sp|P70498|PLD2_RAT Phospholipase D2 (PLD 2) (Choline phosph... 32 1.6 sp|Q9PQA5|MRAZ_UREPA Protein mraZ 30 5.9 sp|P40537|ULP2_YEAST Ubiquitin-like-specific protease 2 30 7.8
>sp|O00291|HIP1_HUMAN Huntingtin interacting protein 1 (HIP-I) Length = 1030 Score = 87.4 bits (215), Expect = 4e-17 Identities = 47/98 (47%), Positives = 62/98 (63%) Frame = +2 Query: 5 QLVVSSRVKANLSSQNFQNLSQASKGVSDATGKVIANAKNAMKVLEEQGSYNFSNLTLTQ 184 QLV +S+VKA+ S N L QAS+GV+ AT V+A+ + +EE + +FS++TLTQ Sbjct: 909 QLVAASKVKADKDSPNLAQLQQASRGVNQATAGVVASTISGKSQIEETDNMDFSSMTLTQ 968 Query: 185 AKRLEMDSQVRVLELENDXXXXXXXXXXXXXXHYQLAG 298 KR EMDSQVRVLELEN+ HY+LAG Sbjct: 969 IKRQEMDSQVRVLELENELQKERQKLGELRKKHYELAG 1006
>sp|Q02328|SLAP2_CAEEL Protein SLA2 homolog Length = 927 Score = 72.4 bits (176), Expect = 1e-12 Identities = 41/97 (42%), Positives = 55/97 (56%) Frame = +2 Query: 5 QLVVSSRVKANLSSQNFQNLSQASKGVSDATGKVIANAKNAMKVLEEQGSYNFSNLTLTQ 184 QL VSSRVKA+ S LS A+K V+ T +V+A KN L ++GS +FS L+L Sbjct: 818 QLFVSSRVKADKDSSKLDALSVAAKAVNQNTAQVVAAVKNGQTTLNDEGSLDFSYLSLHA 877 Query: 185 AKRLEMDSQVRVLELENDXXXXXXXXXXXXXXHYQLA 295 AK+ EM+SQV++LELE HY +A Sbjct: 878 AKKEEMESQVKMLELEQSLNQERAKLAALRKQHYHMA 914
>sp|O75146|HIP1R_HUMAN Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12) Length = 1068 Score = 70.9 bits (172), Expect = 4e-12 Identities = 37/106 (34%), Positives = 60/106 (56%) Frame = +2 Query: 5 QLVVSSRVKANLSSQNFQNLSQASKGVSDATGKVIANAKNAMKVLEEQGSYNFSNLTLTQ 184 QLV +S+VKAN S + L + S+ V++ V+A+ K+ + +E++ + +FS L+L + Sbjct: 916 QLVAASKVKANKHSPHLSRLQECSRTVNERAANVVASTKSGQEQIEDRDTMDFSGLSLIK 975 Query: 185 AKRLEMDSQVRVLELENDXXXXXXXXXXXXXXHYQLAGESADQNDK 322 K+ EM++QVRVLELE HY LAG S ++ Sbjct: 976 LKKQEMETQVRVLELEKTLEAERMRLGELRKQHYVLAGASGSPGEE 1021
>sp|Q9JKY5|HIP1R_MOUSE Huntingtin interacting protein 1 related (Hip1-related) Length = 1068 Score = 69.7 bits (169), Expect = 9e-12 Identities = 36/98 (36%), Positives = 58/98 (59%) Frame = +2 Query: 5 QLVVSSRVKANLSSQNFQNLSQASKGVSDATGKVIANAKNAMKVLEEQGSYNFSNLTLTQ 184 QLV +S+VKAN +S + L + S+ V++ V+A+ K+ + +E++ + +FS L+L + Sbjct: 916 QLVAASKVKANKNSPHLSRLQECSRTVNERAANVVASTKSGQEQIEDRDTMDFSGLSLIK 975 Query: 185 AKRLEMDSQVRVLELENDXXXXXXXXXXXXXXHYQLAG 298 K+ EM++QVRVLELE HY LAG Sbjct: 976 LKKQEMETQVRVLELEKTLEAERVRLGELRKQHYVLAG 1013
>sp|Q9P6L5|SLA2_SCHPO Endocytosis protein end4 (SLA2 protein homolog) Length = 1092 Score = 53.5 bits (127), Expect = 7e-07 Identities = 28/78 (35%), Positives = 50/78 (64%) Frame = +2 Query: 5 QLVVSSRVKANLSSQNFQNLSQASKGVSDATGKVIANAKNAMKVLEEQGSYNFSNLTLTQ 184 QLV +SRVKAN +S+ +L A+K V++A ++ ++ +E +FS+L + + Sbjct: 994 QLVAASRVKANFASKVQDHLEDAAKAVTEACKALVRQVESVALKAKEVQHEDFSSLGVHE 1053 Query: 185 AKRLEMDSQVRVLELEND 238 +R E++ QV++L+LEND Sbjct: 1054 YRRKEIEQQVQILKLEND 1071
>sp|P33338|SLA2_YEAST Protein SLA2 (Transmembrane protein MOP2) Length = 968 Score = 35.4 bits (80), Expect = 0.18 Identities = 26/81 (32%), Positives = 40/81 (49%), Gaps = 5/81 (6%) Frame = +2 Query: 5 QLVVSSRVKANLSSQNFQNLSQASKGVSDATGKVIANAKNAMKVLEEQGSYNFSNLTLT- 181 QLV +SRVK ++ S+ L SK V+DA + + M ++E+ S + L Sbjct: 867 QLVAASRVKTSIHSKAQDKLEHCSKDVTDACRSL---GNHVMGMIEDDHSTSQQQQPLDF 923 Query: 182 ----QAKRLEMDSQVRVLELE 232 K EM+ QV +L+LE Sbjct: 924 TSEHTLKTAEMEQQVEILKLE 944
>sp|Q10432|YQ37_SCHPO Hypothetical protein C188.07 in chromosome III Length = 735 Score = 32.3 bits (72), Expect = 1.6 Identities = 22/79 (27%), Positives = 37/79 (46%), Gaps = 4/79 (5%) Frame = +2 Query: 2 TQLVVSSRVKANLSSQNFQNLSQASKGVSDATGKVIANAKNAM----KVLEEQGSYNFSN 169 TQL+ + + A+ + +QN S + S K+ A K KV+EE YN S Sbjct: 637 TQLLKTQKEDADFITNQYQNASTFAAEQSKEVAKLQAECKRLQAINSKVMEEVKVYNDSR 696 Query: 170 LTLTQAKRLEMDSQVRVLE 226 + AK ++ +++LE Sbjct: 697 VEALLAKVSSLEETLKILE 715
>sp|P70498|PLD2_RAT Phospholipase D2 (PLD 2) (Choline phosphatase 2) (Phosphatidylcholine-hydrolyzing phospholipase D2) (PLD1C) (rPLD2) Length = 933 Score = 32.3 bits (72), Expect = 1.6 Identities = 10/22 (45%), Positives = 14/22 (63%) Frame = -3 Query: 95 LHQKHLYWLEKDFENFVMKDWL 30 L H +WL KD+ N + KDW+ Sbjct: 499 LSHNHFFWLGKDYSNLITKDWV 520
>sp|Q9PQA5|MRAZ_UREPA Protein mraZ Length = 145 Score = 30.4 bits (67), Expect = 5.9 Identities = 23/82 (28%), Positives = 40/82 (48%), Gaps = 5/82 (6%) Frame = +2 Query: 5 QLVVSSRVKANLSSQNFQNLSQASKGVSDAT-----GKVIANAKNAMKVLEEQGSYNFSN 169 +++V S+VKA L F LS G D + + N N + + + + N + Sbjct: 15 RMLVPSKVKATLGEAIFVYLSLGFDGNIDMRLESEFNQFVNNINNLL--IGSKEARNLTR 72 Query: 170 LTLTQAKRLEMDSQVRVLELEN 235 L L+Q ++E+DS R+L +N Sbjct: 73 LILSQTYKIEIDSASRILIPQN 94
>sp|P40537|ULP2_YEAST Ubiquitin-like-specific protease 2 Length = 1034 Score = 30.0 bits (66), Expect = 7.8 Identities = 11/29 (37%), Positives = 18/29 (62%) Frame = +3 Query: 690 NLFQ*SIIDFPLKIKFKWFICIISNLNRL 776 +LF + P+ I + WF CII+NL+ + Sbjct: 515 DLFSKKYVVIPINISYHWFSCIITNLDAI 543
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 73,011,105 Number of Sequences: 369166 Number of extensions: 1271614 Number of successful extensions: 2866 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 2811 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 2865 length of database: 68,354,980 effective HSP length: 109 effective length of database: 48,218,865 effective search space used: 7666799535 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)