Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_01575 (919 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q9WUB0|UB7I3_MOUSE Ubiquitin-conjugating enzyme 7-intera... 78 4e-14 sp|Q62921|UB7I3_RAT Ubiquitin-conjugating enzyme 7-interact... 75 2e-13 sp|Q9BYM8|UB7I3_HUMAN Ubiquitin-conjugating enzyme 7-intera... 74 7e-13 sp|Q9Y4X5|ARI1_HUMAN Ariadne-1 protein homolog (ARI-1) (Ubi... 44 8e-04 sp|Q9Z1K5|ARI1_MOUSE Ariadne-1 protein homolog (ARI-1) (Ubi... 44 8e-04 sp|Q8VC56|RNF8_MOUSE Ubiquitin ligase protein RNF8 (RING fi... 41 0.004 sp|O76064|RNF8_HUMAN Ubiquitin ligase protein RNF8 (RING fi... 41 0.004 sp|Q96EP0|RNF31_HUMAN RING finger protein 31 (Zinc in-betwe... 39 0.020 sp|Q6ZMZ0|IBR3_HUMAN IBR domain containing protein 3 39 0.020 sp|P50636|RNF19_MOUSE RING finger protein 19 (XY body prote... 38 0.045
>sp|Q9WUB0|UB7I3_MOUSE Ubiquitin-conjugating enzyme 7-interacting protein 3 (UbcM4-interacting protein 28) Length = 498 Score = 77.8 bits (190), Expect = 4e-14 Identities = 40/136 (29%), Positives = 67/136 (49%), Gaps = 9/136 (6%) Frame = +2 Query: 146 TNCLLCNYFKDESEIVILK-CSHSFCWICINNYLKVNLSPKVKCPLSN----CSEIIRDS 310 T C +C E V+L+ C H+FC C+ ++ + +V CP + C + + Sbjct: 268 TECPVCYSVLAPGEAVVLRECLHTFCRECLQGTIRNSQEAEVACPFIDSTYSCPGKLLER 327 Query: 311 QIRRVLPDEMIETYENLCVGIINK----SHHCLLPGCSGSIIYTDEDVQYACPLCTLYNC 478 +IR +L E + + +L V I S+HC P C G + D+ ++ CP+CT NC Sbjct: 328 EIRALLSPEDYQRFLDLGVSIAENRSTLSYHCKTPDCRGWCFFEDDVNEFTCPVCTRVNC 387 Query: 479 VKCNAAHNFVTCSEFK 526 + C A H + C E++ Sbjct: 388 LLCKAIHEHMNCREYQ 403
>sp|Q62921|UB7I3_RAT Ubiquitin-conjugating enzyme 7-interacting protein 3 (RBCC protein interacting with PKC) (Protein kinase C-binding protein beta-15) Length = 498 Score = 75.5 bits (184), Expect = 2e-13 Identities = 39/134 (29%), Positives = 66/134 (49%), Gaps = 9/134 (6%) Frame = +2 Query: 152 CLLCNYFKDESEIVILK-CSHSFCWICINNYLKVNLSPKVKCPLSN----CSEIIRDSQI 316 C +C E V+L+ C H+FC C+ ++ + +V CP + C + + +I Sbjct: 270 CPVCYSVLAPGEAVVLRECLHTFCRECLQGTIRNSQEAEVSCPFIDNTYSCPGKLLEREI 329 Query: 317 RRVLPDEMIETYENLCVGIINK----SHHCLLPGCSGSIIYTDEDVQYACPLCTLYNCVK 484 R +L E + + +L V I S+HC P C G + D+ ++ CP+CT NC+ Sbjct: 330 RALLSPEDYQRFLDLGVSIAENRSTLSYHCKTPDCRGWCFFEDDVNEFTCPVCTRVNCLL 389 Query: 485 CNAAHNFVTCSEFK 526 C A H + C E++ Sbjct: 390 CKAIHERMNCREYQ 403
>sp|Q9BYM8|UB7I3_HUMAN Ubiquitin-conjugating enzyme 7-interacting protein 3 (Hepatitis B virus X-associated protein 4) (HBV-associated factor 4) (RING finger protein 54) Length = 500 Score = 73.6 bits (179), Expect = 7e-13 Identities = 37/134 (27%), Positives = 66/134 (49%), Gaps = 9/134 (6%) Frame = +2 Query: 152 CLLCNYFKDESEIVILK-CSHSFCWICINNYLKVNLSPKVKCPLSN----CSEIIRDSQI 316 C +C E V+L+ C H+FC C+ ++ + +V CP + CS + + +I Sbjct: 272 CPVCYSVLAPGEAVVLRECLHTFCRECLQGTIRNSQEAEVSCPFIDNTYSCSGKLLEREI 331 Query: 317 RRVLPDEMIETYENLCVGIINK----SHHCLLPGCSGSIIYTDEDVQYACPLCTLYNCVK 484 + +L E + + +L + I S+HC P C G + D+ ++ CP+C NC+ Sbjct: 332 KALLTPEDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFEDDVNEFTCPVCFHVNCLL 391 Query: 485 CNAAHNFVTCSEFK 526 C A H + C E++ Sbjct: 392 CKAIHEQMNCKEYQ 405
>sp|Q9Y4X5|ARI1_HUMAN Ariadne-1 protein homolog (ARI-1) (Ubiquitin-conjugating enzyme E2-binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein) (HHARI) (H7-AP2) (MOP-6) Length = 557 Score = 43.5 bits (101), Expect = 8e-04 Identities = 37/139 (26%), Positives = 56/139 (40%), Gaps = 14/139 (10%) Frame = +2 Query: 152 CLLCNYFKDESEIVILKCSHSFCWICINNYLKVNLSPK-----VKCPLSNCSEIIRDSQI 316 C +C S L+C H FC C + YL + + + CP C ++ D+ + Sbjct: 186 CQICYLNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDDNTV 245 Query: 317 RRVLPDEMIE-TYENLCVGIINKSHHC--LLPGCSGSIIYTDEDVQY--ACPL---CTLY 472 R++ D ++ Y++L I N C LL C + VQY A P+ C Sbjct: 246 MRLITDSKVKLKYQHL---ITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCKCGRQ 302 Query: 473 NCVKCNAA-HNFVTCSEFK 526 C C H+ V C K Sbjct: 303 FCFNCGENWHDPVKCKWLK 321
>sp|Q9Z1K5|ARI1_MOUSE Ariadne-1 protein homolog (ARI-1) (Ubiquitin-conjugating enzyme E2-binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein 77) Length = 555 Score = 43.5 bits (101), Expect = 8e-04 Identities = 37/139 (26%), Positives = 56/139 (40%), Gaps = 14/139 (10%) Frame = +2 Query: 152 CLLCNYFKDESEIVILKCSHSFCWICINNYLKVNLSPK-----VKCPLSNCSEIIRDSQI 316 C +C S L+C H FC C + YL + + + CP C ++ D+ + Sbjct: 184 CQICYLNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDDNTV 243 Query: 317 RRVLPDEMIE-TYENLCVGIINKSHHC--LLPGCSGSIIYTDEDVQY--ACPL---CTLY 472 R++ D ++ Y++L I N C LL C + VQY A P+ C Sbjct: 244 MRLITDSKVKLKYQHL---ITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCKCGRQ 300 Query: 473 NCVKCNAA-HNFVTCSEFK 526 C C H+ V C K Sbjct: 301 FCFNCGENWHDPVKCKWLK 319
>sp|Q8VC56|RNF8_MOUSE Ubiquitin ligase protein RNF8 (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180) Length = 488 Score = 41.2 bits (95), Expect = 0.004 Identities = 26/71 (36%), Positives = 39/71 (54%), Gaps = 1/71 (1%) Frame = +2 Query: 152 CLLCN-YFKDESEIVILKCSHSFCWICINNYLKVNLSPKVKCPLSNCSEIIRDSQIRRVL 328 C++C+ YF E V L C+HSFC CIN ++K KV+CP+ C + I VL Sbjct: 406 CIICSEYF---IEAVTLNCAHSFCSFCINEWMK----RKVECPI--CRKDIESRTNSLVL 456 Query: 329 PDEMIETYENL 361 + + + +NL Sbjct: 457 DNCISKMVDNL 467
>sp|O76064|RNF8_HUMAN Ubiquitin ligase protein RNF8 (RING finger protein 8) Length = 485 Score = 41.2 bits (95), Expect = 0.004 Identities = 25/71 (35%), Positives = 39/71 (54%), Gaps = 1/71 (1%) Frame = +2 Query: 152 CLLCN-YFKDESEIVILKCSHSFCWICINNYLKVNLSPKVKCPLSNCSEIIRDSQIRRVL 328 C++C+ YF E V L C+HSFC CIN ++K K++CP+ C + I+ VL Sbjct: 403 CIICSEYF---IEAVTLNCAHSFCSYCINEWMK----RKIECPI--CRKDIKSKTYSLVL 453 Query: 329 PDEMIETYENL 361 + + + NL Sbjct: 454 DNCINKMVNNL 464
>sp|Q96EP0|RNF31_HUMAN RING finger protein 31 (Zinc in-between-RING-finger ubiquitin-associated domain protein) Length = 1072 Score = 38.9 bits (89), Expect = 0.020 Identities = 32/155 (20%), Positives = 58/155 (37%), Gaps = 22/155 (14%) Frame = +2 Query: 128 IRN*IMTNCLLCNYFKDESEIVIL-KCSHSFCWICINNYLKVNLSPK----VKCPLSNCS 292 +R + C +C + + + L C + C C + + L K + CP Sbjct: 691 LRRLLAQECAVCGWALPHNRMQALTSCECTICPDCFRQHFTIALKEKHITDMVCPACGRP 750 Query: 293 EIIRDSQI------------RRVLPDEMIETYENLCVGIINKSHHCL-LPGCSGSIIYTD 433 ++ D+Q+ + PD ++ L G++ + L CS IY Sbjct: 751 DLTDDTQLLSYFSTLDIQLRESLEPDAYALFHKKLTEGVLMRDPKFLWCAQCSFGFIYER 810 Query: 434 EDVQYACPLCTLYNCVKC----NAAHNFVTCSEFK 526 E ++ CP C CV+C H +C +F+ Sbjct: 811 EQLEATCPQCHQTFCVRCKRQWEEQHRGRSCEDFQ 845
>sp|Q6ZMZ0|IBR3_HUMAN IBR domain containing protein 3 Length = 486 Score = 38.9 bits (89), Expect = 0.020 Identities = 28/103 (27%), Positives = 42/103 (40%), Gaps = 8/103 (7%) Frame = +2 Query: 194 ILKCSHSFCWICINNYLKVNLSPK---VKCPLSNCSEIIRDSQIRRVLPD-EMIETYENL 361 +L C H C C+ +YL++ +S + CP CSE + IR +L D ++ YE Sbjct: 33 LLSCPHRSCRDCLRHYLRLEISESRVPISCP--ECSERLNPHDIRLLLADPPLMHKYEEF 90 Query: 362 CVGIINKS----HHCLLPGCSGSIIYTDEDVQYACPLCTLYNC 478 + S C P C ++I Y C C C Sbjct: 91 MLRRYLASDPDCRWCPAPDCGYAVI------AYGCASCPKLTC 127
>sp|P50636|RNF19_MOUSE RING finger protein 19 (XY body protein) (XYbp) (Gametogenesis expressed protein GEG-154) (UBCM4-interacting protein 117) (UIP117) Length = 840 Score = 37.7 bits (86), Expect = 0.045 Identities = 26/103 (25%), Positives = 41/103 (39%), Gaps = 8/103 (7%) Frame = +2 Query: 194 ILKCSHSFCWICINNYLKVNLSP---KVKCPLSNCSEIIRDSQIRRVLPDE-MIETYENL 361 I+ C H C C+ YL++ +S + CP C+E IR +L D+ ++E YE Sbjct: 147 IMTCHHRSCVDCLRQYLRIEISESRVNISCP--ECTERFNPHDIRLILSDDVLMEKYEEF 204 Query: 362 CVG----IINKSHHCLLPGCSGSIIYTDEDVQYACPLCTLYNC 478 + C P C ++I + C C C Sbjct: 205 MLRRWLVADPDCRWCPAPDCGYAVI------AFGCASCPKLTC 241
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 94,071,275 Number of Sequences: 369166 Number of extensions: 1808491 Number of successful extensions: 4107 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 3941 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4099 length of database: 68,354,980 effective HSP length: 110 effective length of database: 48,034,130 effective search space used: 9366655350 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)