Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_007_D10
(919 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9WUB0|UB7I3_MOUSE Ubiquitin-conjugating enzyme 7-intera... 78 4e-14
sp|Q62921|UB7I3_RAT Ubiquitin-conjugating enzyme 7-interact... 75 2e-13
sp|Q9BYM8|UB7I3_HUMAN Ubiquitin-conjugating enzyme 7-intera... 74 7e-13
sp|Q9Y4X5|ARI1_HUMAN Ariadne-1 protein homolog (ARI-1) (Ubi... 44 8e-04
sp|Q9Z1K5|ARI1_MOUSE Ariadne-1 protein homolog (ARI-1) (Ubi... 44 8e-04
sp|Q8VC56|RNF8_MOUSE Ubiquitin ligase protein RNF8 (RING fi... 41 0.004
sp|O76064|RNF8_HUMAN Ubiquitin ligase protein RNF8 (RING fi... 41 0.004
sp|Q96EP0|RNF31_HUMAN RING finger protein 31 (Zinc in-betwe... 39 0.020
sp|Q6ZMZ0|IBR3_HUMAN IBR domain containing protein 3 39 0.020
sp|P50636|RNF19_MOUSE RING finger protein 19 (XY body prote... 38 0.045
>sp|Q9WUB0|UB7I3_MOUSE Ubiquitin-conjugating enzyme 7-interacting protein 3
(UbcM4-interacting protein 28)
Length = 498
Score = 77.8 bits (190), Expect = 4e-14
Identities = 40/136 (29%), Positives = 67/136 (49%), Gaps = 9/136 (6%)
Frame = +2
Query: 146 TNCLLCNYFKDESEIVILK-CSHSFCWICINNYLKVNLSPKVKCPLSN----CSEIIRDS 310
T C +C E V+L+ C H+FC C+ ++ + +V CP + C + +
Sbjct: 268 TECPVCYSVLAPGEAVVLRECLHTFCRECLQGTIRNSQEAEVACPFIDSTYSCPGKLLER 327
Query: 311 QIRRVLPDEMIETYENLCVGIINK----SHHCLLPGCSGSIIYTDEDVQYACPLCTLYNC 478
+IR +L E + + +L V I S+HC P C G + D+ ++ CP+CT NC
Sbjct: 328 EIRALLSPEDYQRFLDLGVSIAENRSTLSYHCKTPDCRGWCFFEDDVNEFTCPVCTRVNC 387
Query: 479 VKCNAAHNFVTCSEFK 526
+ C A H + C E++
Sbjct: 388 LLCKAIHEHMNCREYQ 403
>sp|Q62921|UB7I3_RAT Ubiquitin-conjugating enzyme 7-interacting protein 3 (RBCC protein
interacting with PKC) (Protein kinase C-binding protein
beta-15)
Length = 498
Score = 75.5 bits (184), Expect = 2e-13
Identities = 39/134 (29%), Positives = 66/134 (49%), Gaps = 9/134 (6%)
Frame = +2
Query: 152 CLLCNYFKDESEIVILK-CSHSFCWICINNYLKVNLSPKVKCPLSN----CSEIIRDSQI 316
C +C E V+L+ C H+FC C+ ++ + +V CP + C + + +I
Sbjct: 270 CPVCYSVLAPGEAVVLRECLHTFCRECLQGTIRNSQEAEVSCPFIDNTYSCPGKLLEREI 329
Query: 317 RRVLPDEMIETYENLCVGIINK----SHHCLLPGCSGSIIYTDEDVQYACPLCTLYNCVK 484
R +L E + + +L V I S+HC P C G + D+ ++ CP+CT NC+
Sbjct: 330 RALLSPEDYQRFLDLGVSIAENRSTLSYHCKTPDCRGWCFFEDDVNEFTCPVCTRVNCLL 389
Query: 485 CNAAHNFVTCSEFK 526
C A H + C E++
Sbjct: 390 CKAIHERMNCREYQ 403
>sp|Q9BYM8|UB7I3_HUMAN Ubiquitin-conjugating enzyme 7-interacting protein 3 (Hepatitis B
virus X-associated protein 4) (HBV-associated factor 4)
(RING finger protein 54)
Length = 500
Score = 73.6 bits (179), Expect = 7e-13
Identities = 37/134 (27%), Positives = 66/134 (49%), Gaps = 9/134 (6%)
Frame = +2
Query: 152 CLLCNYFKDESEIVILK-CSHSFCWICINNYLKVNLSPKVKCPLSN----CSEIIRDSQI 316
C +C E V+L+ C H+FC C+ ++ + +V CP + CS + + +I
Sbjct: 272 CPVCYSVLAPGEAVVLRECLHTFCRECLQGTIRNSQEAEVSCPFIDNTYSCSGKLLEREI 331
Query: 317 RRVLPDEMIETYENLCVGIINK----SHHCLLPGCSGSIIYTDEDVQYACPLCTLYNCVK 484
+ +L E + + +L + I S+HC P C G + D+ ++ CP+C NC+
Sbjct: 332 KALLTPEDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFEDDVNEFTCPVCFHVNCLL 391
Query: 485 CNAAHNFVTCSEFK 526
C A H + C E++
Sbjct: 392 CKAIHEQMNCKEYQ 405
>sp|Q9Y4X5|ARI1_HUMAN Ariadne-1 protein homolog (ARI-1) (Ubiquitin-conjugating enzyme
E2-binding protein 1) (UbcH7-binding protein)
(UbcM4-interacting protein) (HHARI) (H7-AP2) (MOP-6)
Length = 557
Score = 43.5 bits (101), Expect = 8e-04
Identities = 37/139 (26%), Positives = 56/139 (40%), Gaps = 14/139 (10%)
Frame = +2
Query: 152 CLLCNYFKDESEIVILKCSHSFCWICINNYLKVNLSPK-----VKCPLSNCSEIIRDSQI 316
C +C S L+C H FC C + YL + + + CP C ++ D+ +
Sbjct: 186 CQICYLNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDDNTV 245
Query: 317 RRVLPDEMIE-TYENLCVGIINKSHHC--LLPGCSGSIIYTDEDVQY--ACPL---CTLY 472
R++ D ++ Y++L I N C LL C + VQY A P+ C
Sbjct: 246 MRLITDSKVKLKYQHL---ITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCKCGRQ 302
Query: 473 NCVKCNAA-HNFVTCSEFK 526
C C H+ V C K
Sbjct: 303 FCFNCGENWHDPVKCKWLK 321
>sp|Q9Z1K5|ARI1_MOUSE Ariadne-1 protein homolog (ARI-1) (Ubiquitin-conjugating enzyme
E2-binding protein 1) (UbcH7-binding protein)
(UbcM4-interacting protein 77)
Length = 555
Score = 43.5 bits (101), Expect = 8e-04
Identities = 37/139 (26%), Positives = 56/139 (40%), Gaps = 14/139 (10%)
Frame = +2
Query: 152 CLLCNYFKDESEIVILKCSHSFCWICINNYLKVNLSPK-----VKCPLSNCSEIIRDSQI 316
C +C S L+C H FC C + YL + + + CP C ++ D+ +
Sbjct: 184 CQICYLNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDDNTV 243
Query: 317 RRVLPDEMIE-TYENLCVGIINKSHHC--LLPGCSGSIIYTDEDVQY--ACPL---CTLY 472
R++ D ++ Y++L I N C LL C + VQY A P+ C
Sbjct: 244 MRLITDSKVKLKYQHL---ITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCKCGRQ 300
Query: 473 NCVKCNAA-HNFVTCSEFK 526
C C H+ V C K
Sbjct: 301 FCFNCGENWHDPVKCKWLK 319
>sp|Q8VC56|RNF8_MOUSE Ubiquitin ligase protein RNF8 (RING finger protein 8) (AIP37)
(ActA-interacting protein 37) (LaXp180)
Length = 488
Score = 41.2 bits (95), Expect = 0.004
Identities = 26/71 (36%), Positives = 39/71 (54%), Gaps = 1/71 (1%)
Frame = +2
Query: 152 CLLCN-YFKDESEIVILKCSHSFCWICINNYLKVNLSPKVKCPLSNCSEIIRDSQIRRVL 328
C++C+ YF E V L C+HSFC CIN ++K KV+CP+ C + I VL
Sbjct: 406 CIICSEYF---IEAVTLNCAHSFCSFCINEWMK----RKVECPI--CRKDIESRTNSLVL 456
Query: 329 PDEMIETYENL 361
+ + + +NL
Sbjct: 457 DNCISKMVDNL 467
>sp|O76064|RNF8_HUMAN Ubiquitin ligase protein RNF8 (RING finger protein 8)
Length = 485
Score = 41.2 bits (95), Expect = 0.004
Identities = 25/71 (35%), Positives = 39/71 (54%), Gaps = 1/71 (1%)
Frame = +2
Query: 152 CLLCN-YFKDESEIVILKCSHSFCWICINNYLKVNLSPKVKCPLSNCSEIIRDSQIRRVL 328
C++C+ YF E V L C+HSFC CIN ++K K++CP+ C + I+ VL
Sbjct: 403 CIICSEYF---IEAVTLNCAHSFCSYCINEWMK----RKIECPI--CRKDIKSKTYSLVL 453
Query: 329 PDEMIETYENL 361
+ + + NL
Sbjct: 454 DNCINKMVNNL 464
>sp|Q96EP0|RNF31_HUMAN RING finger protein 31 (Zinc in-between-RING-finger
ubiquitin-associated domain protein)
Length = 1072
Score = 38.9 bits (89), Expect = 0.020
Identities = 32/155 (20%), Positives = 58/155 (37%), Gaps = 22/155 (14%)
Frame = +2
Query: 128 IRN*IMTNCLLCNYFKDESEIVIL-KCSHSFCWICINNYLKVNLSPK----VKCPLSNCS 292
+R + C +C + + + L C + C C + + L K + CP
Sbjct: 691 LRRLLAQECAVCGWALPHNRMQALTSCECTICPDCFRQHFTIALKEKHITDMVCPACGRP 750
Query: 293 EIIRDSQI------------RRVLPDEMIETYENLCVGIINKSHHCL-LPGCSGSIIYTD 433
++ D+Q+ + PD ++ L G++ + L CS IY
Sbjct: 751 DLTDDTQLLSYFSTLDIQLRESLEPDAYALFHKKLTEGVLMRDPKFLWCAQCSFGFIYER 810
Query: 434 EDVQYACPLCTLYNCVKC----NAAHNFVTCSEFK 526
E ++ CP C CV+C H +C +F+
Sbjct: 811 EQLEATCPQCHQTFCVRCKRQWEEQHRGRSCEDFQ 845
>sp|Q6ZMZ0|IBR3_HUMAN IBR domain containing protein 3
Length = 486
Score = 38.9 bits (89), Expect = 0.020
Identities = 28/103 (27%), Positives = 42/103 (40%), Gaps = 8/103 (7%)
Frame = +2
Query: 194 ILKCSHSFCWICINNYLKVNLSPK---VKCPLSNCSEIIRDSQIRRVLPD-EMIETYENL 361
+L C H C C+ +YL++ +S + CP CSE + IR +L D ++ YE
Sbjct: 33 LLSCPHRSCRDCLRHYLRLEISESRVPISCP--ECSERLNPHDIRLLLADPPLMHKYEEF 90
Query: 362 CVGIINKS----HHCLLPGCSGSIIYTDEDVQYACPLCTLYNC 478
+ S C P C ++I Y C C C
Sbjct: 91 MLRRYLASDPDCRWCPAPDCGYAVI------AYGCASCPKLTC 127
>sp|P50636|RNF19_MOUSE RING finger protein 19 (XY body protein) (XYbp) (Gametogenesis
expressed protein GEG-154) (UBCM4-interacting protein
117) (UIP117)
Length = 840
Score = 37.7 bits (86), Expect = 0.045
Identities = 26/103 (25%), Positives = 41/103 (39%), Gaps = 8/103 (7%)
Frame = +2
Query: 194 ILKCSHSFCWICINNYLKVNLSP---KVKCPLSNCSEIIRDSQIRRVLPDE-MIETYENL 361
I+ C H C C+ YL++ +S + CP C+E IR +L D+ ++E YE
Sbjct: 147 IMTCHHRSCVDCLRQYLRIEISESRVNISCP--ECTERFNPHDIRLILSDDVLMEKYEEF 204
Query: 362 CVG----IINKSHHCLLPGCSGSIIYTDEDVQYACPLCTLYNC 478
+ C P C ++I + C C C
Sbjct: 205 MLRRWLVADPDCRWCPAPDCGYAVI------AFGCASCPKLTC 241
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 94,071,275
Number of Sequences: 369166
Number of extensions: 1808491
Number of successful extensions: 4107
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3941
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4099
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9366655350
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)