Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_01573 (957 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q7TQH0|ATX2L_MOUSE Ataxin-2-like protein 34 0.69 sp|O83269|RPOB_TREPA DNA-directed RNA polymerase beta chain... 33 1.2 sp|P35884|TRA2_THIFE Transposase for insertion sequence ele... 33 1.5 sp|Q871U2|ATG7_NEUCR Autophagy-related protein 7 (Autophagy... 32 3.4 sp|P15392|CP2A4_MOUSE Cytochrome P450 2A4 (CYPIIA4) (Testos... 31 4.5 sp|P20852|CP2A5_MOUSE Cytochrome P450 2A5 (CYPIIA5) (Coumar... 31 5.9 sp|P11837|NIMA_EMENI G2-specific protein kinase nimA (Never... 31 5.9 sp|P41817|CUP9_YEAST Homeobox protein CUP9 31 5.9 sp|Q8WXX7|AUTS2_HUMAN Autism susceptibility gene 2 protein 31 5.9 sp|Q02447|SP3_HUMAN Transcription factor Sp3 (SPR-2) 31 5.9
>sp|Q7TQH0|ATX2L_MOUSE Ataxin-2-like protein Length = 1049 Score = 33.9 bits (76), Expect = 0.69 Identities = 32/124 (25%), Positives = 48/124 (38%), Gaps = 14/124 (11%) Frame = +3 Query: 519 SPQPVKMIPRMGYPGGDAHMIGREVMYDTPPSGHDPRIMVAPPGMVLVQPGMSHH----- 683 +PQ + YP + G + T P+G P+ A P V Q G + H Sbjct: 853 TPQALYATVHQSYPHHATQLHGHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQ 912 Query: 684 -DQNWVHLNNTLTRRGTPTLFVEPPRIRD--------YSEYGIPPNQMVPIQPQQLAHLS 836 QN H LT GTP P + + Y I P+Q +P +AH++ Sbjct: 913 PQQNLYH-PGALT--GTPPSLPPGPSAQSPQSSFPQPAAVYAIHPHQQLPHGFTNMAHVT 969 Query: 837 QQNL 848 Q ++ Sbjct: 970 QAHV 973
>sp|O83269|RPOB_TREPA DNA-directed RNA polymerase beta chain (RNAP beta subunit) (Transcriptase beta chain) (RNA polymerase beta subunit) Length = 1178 Score = 33.1 bits (74), Expect = 1.2 Identities = 19/73 (26%), Positives = 37/73 (50%), Gaps = 3/73 (4%) Frame = +3 Query: 666 PGMSHHDQNWVHLNNTLTRRGTPTLFVEPPRIRDYSEYGIPPNQMVPIQPQQ---LAHLS 836 P + H D N + + + R+G P +F EPPR+ E + V ++ +Q +A++S Sbjct: 640 PFLEHDDANRALMGSNMQRQGVPLIFPEPPRVGTGMEEKCAYDSGVLVKAKQDGTVAYVS 699 Query: 837 QQNLHLHNQNLSG 875 + + + + SG Sbjct: 700 SEKIVVCSAAASG 712
>sp|P35884|TRA2_THIFE Transposase for insertion sequence element IST2 Length = 296 Score = 32.7 bits (73), Expect = 1.5 Identities = 18/63 (28%), Positives = 29/63 (46%), Gaps = 9/63 (14%) Frame = +3 Query: 576 MIGREVMYDTPPSGHDPRIMV---------APPGMVLVQPGMSHHDQNWVHLNNTLTRRG 728 ++GR +Y+ PP G DPRI + +V+V G+ +W+ + L RG Sbjct: 47 LVGRRYLYE-PPCGEDPRICLLVIIGVTAEGKKELVMVSDGLRESKASWLEILRDLQARG 105 Query: 729 TPT 737 T Sbjct: 106 LET 108
>sp|Q871U2|ATG7_NEUCR Autophagy-related protein 7 (Autophagy-related E1-like-activating enzyme atg-7) Length = 699 Score = 31.6 bits (70), Expect = 3.4 Identities = 20/66 (30%), Positives = 22/66 (33%) Frame = +3 Query: 33 APGPASLPTGSLLRQNTNQMHHPAQYCPPQYAPIPQQMYYTGGNGFVYPQCSYMVSPXXX 212 AP P S TGS + + HP P Q G YPQCS P Sbjct: 581 APAPVSTGTGSAVSYERDPPDHPLGLVPHQVRGFLSNFQNMVIRGKSYPQCSACSKPILD 640 Query: 213 XXXTGG 230 GG Sbjct: 641 AYKEGG 646
>sp|P15392|CP2A4_MOUSE Cytochrome P450 2A4 (CYPIIA4) (Testosterone 15-alpha-hydroxylase) (P450-15-alpha) (P450-IIA3.1) Length = 494 Score = 31.2 bits (69), Expect = 4.5 Identities = 14/37 (37%), Positives = 21/37 (56%), Gaps = 1/37 (2%) Frame = +3 Query: 27 KIAPGPASLP-TGSLLRQNTNQMHHPAQYCPPQYAPI 134 K+ PGP LP G+ L+ NT QM++ +Y P+ Sbjct: 32 KLPPGPTPLPFVGNFLQLNTEQMYNSLMKISQRYGPV 68
>sp|P20852|CP2A5_MOUSE Cytochrome P450 2A5 (CYPIIA5) (Coumarin 7-hydroxylase) (P450-15-COH) (P450-IIA3.2) Length = 494 Score = 30.8 bits (68), Expect = 5.9 Identities = 14/37 (37%), Positives = 21/37 (56%), Gaps = 1/37 (2%) Frame = +3 Query: 27 KIAPGPASLP-TGSLLRQNTNQMHHPAQYCPPQYAPI 134 K+ PGP LP G+ L+ NT QM++ +Y P+ Sbjct: 32 KLPPGPTPLPFIGNFLQLNTEQMYNSLMKISQRYGPV 68
>sp|P11837|NIMA_EMENI G2-specific protein kinase nimA (Never in mitosis) Length = 699 Score = 30.8 bits (68), Expect = 5.9 Identities = 15/46 (32%), Positives = 22/46 (47%) Frame = +3 Query: 9 PAVTYYKIAPGPASLPTGSLLRQNTNQMHHPAQYCPPQYAPIPQQM 146 P+ T K+ P P P+ LLRQNT + PP + P ++ Sbjct: 520 PSPTRPKVKPDPFKAPSRPLLRQNTTALMQKLSTQPPIFPANPSRL 565
>sp|P41817|CUP9_YEAST Homeobox protein CUP9 Length = 306 Score = 30.8 bits (68), Expect = 5.9 Identities = 28/124 (22%), Positives = 50/124 (40%), Gaps = 1/124 (0%) Frame = +3 Query: 69 LRQNTNQMHHPAQYCPPQYAPIPQQMYYTGGNGFVYPQCSYMVSPXXXXXXTGGSGSHA- 245 LR +T + ++PA PQ+ I +GG S +P T + S A Sbjct: 51 LRSSTEEQNYPAPVLLPQHHSIAYPAINSGGT-------STTATPTASTVETSKTSSSAM 103 Query: 246 TISNQGGSGQQMKQEFNDMRSQDGGESVYSYFSQTSNAGVPRHDLVHGTVEAGSQTINSN 425 +Q GS ++ K +D + +Y ++ +AG + VE+ S+ ++ Sbjct: 104 DTQSQYGSSKKSKSASDDAKPCYKSAPIYEIINKEKDAGAQYNRPFSDFVESKSRRKQNS 163 Query: 426 GTGS 437 G S Sbjct: 164 GRRS 167
>sp|Q8WXX7|AUTS2_HUMAN Autism susceptibility gene 2 protein Length = 1259 Score = 30.8 bits (68), Expect = 5.9 Identities = 30/115 (26%), Positives = 44/115 (38%), Gaps = 7/115 (6%) Frame = +3 Query: 6 PPAVTYYKIA-PGPASLPTGSLLRQNTNQM------HHPAQYCPPQYAPIPQQMYYTGGN 164 PP ++++ A P P SLP S L T + HHP + PP P P + T G+ Sbjct: 419 PPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPL--TSGS 476 Query: 165 GFVYPQCSYMVSPXXXXXXTGGSGSHATISNQGGSGQQMKQEFNDMRSQDGGESV 329 G + +T S Q Q++ F +S D G S+ Sbjct: 477 -----------------LQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASL 514
>sp|Q02447|SP3_HUMAN Transcription factor Sp3 (SPR-2) Length = 781 Score = 30.8 bits (68), Expect = 5.9 Identities = 22/104 (21%), Positives = 41/104 (39%) Frame = +3 Query: 252 SNQGGSGQQMKQEFNDMRSQDGGESVYSYFSQTSNAGVPRHDLVHGTVEAGSQTINSNGT 431 S+ G Q ++S DG + + + N G+ + + +QT+ ++GT Sbjct: 160 SSNGTVSSVQYQVIPQIQSADGQQVQIGFTGSSDNGGINQESSQIQIIPGSNQTLLASGT 219 Query: 432 GSASXXXXXXXXXXTNHSGITLSENSDNCSPQPVKMIPRMGYPG 563 SA+ G+ + +S Q V +P +G PG Sbjct: 220 PSANIQNLIPQTGQVQVQGVAIGGSSFPGQTQVVANVP-LGLPG 262
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 121,480,140 Number of Sequences: 369166 Number of extensions: 2777537 Number of successful extensions: 8140 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 7603 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 8120 length of database: 68,354,980 effective HSP length: 111 effective length of database: 47,849,395 effective search space used: 9904824765 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)