Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_007_D05
(957 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q7TQH0|ATX2L_MOUSE Ataxin-2-like protein 34 0.69
sp|O83269|RPOB_TREPA DNA-directed RNA polymerase beta chain... 33 1.2
sp|P35884|TRA2_THIFE Transposase for insertion sequence ele... 33 1.5
sp|Q871U2|ATG7_NEUCR Autophagy-related protein 7 (Autophagy... 32 3.4
sp|P15392|CP2A4_MOUSE Cytochrome P450 2A4 (CYPIIA4) (Testos... 31 4.5
sp|P20852|CP2A5_MOUSE Cytochrome P450 2A5 (CYPIIA5) (Coumar... 31 5.9
sp|P11837|NIMA_EMENI G2-specific protein kinase nimA (Never... 31 5.9
sp|P41817|CUP9_YEAST Homeobox protein CUP9 31 5.9
sp|Q8WXX7|AUTS2_HUMAN Autism susceptibility gene 2 protein 31 5.9
sp|Q02447|SP3_HUMAN Transcription factor Sp3 (SPR-2) 31 5.9
>sp|Q7TQH0|ATX2L_MOUSE Ataxin-2-like protein
Length = 1049
Score = 33.9 bits (76), Expect = 0.69
Identities = 32/124 (25%), Positives = 48/124 (38%), Gaps = 14/124 (11%)
Frame = +3
Query: 519 SPQPVKMIPRMGYPGGDAHMIGREVMYDTPPSGHDPRIMVAPPGMVLVQPGMSHH----- 683
+PQ + YP + G + T P+G P+ A P V Q G + H
Sbjct: 853 TPQALYATVHQSYPHHATQLHGHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQ 912
Query: 684 -DQNWVHLNNTLTRRGTPTLFVEPPRIRD--------YSEYGIPPNQMVPIQPQQLAHLS 836
QN H LT GTP P + + Y I P+Q +P +AH++
Sbjct: 913 PQQNLYH-PGALT--GTPPSLPPGPSAQSPQSSFPQPAAVYAIHPHQQLPHGFTNMAHVT 969
Query: 837 QQNL 848
Q ++
Sbjct: 970 QAHV 973
>sp|O83269|RPOB_TREPA DNA-directed RNA polymerase beta chain (RNAP beta subunit)
(Transcriptase beta chain) (RNA polymerase beta subunit)
Length = 1178
Score = 33.1 bits (74), Expect = 1.2
Identities = 19/73 (26%), Positives = 37/73 (50%), Gaps = 3/73 (4%)
Frame = +3
Query: 666 PGMSHHDQNWVHLNNTLTRRGTPTLFVEPPRIRDYSEYGIPPNQMVPIQPQQ---LAHLS 836
P + H D N + + + R+G P +F EPPR+ E + V ++ +Q +A++S
Sbjct: 640 PFLEHDDANRALMGSNMQRQGVPLIFPEPPRVGTGMEEKCAYDSGVLVKAKQDGTVAYVS 699
Query: 837 QQNLHLHNQNLSG 875
+ + + + SG
Sbjct: 700 SEKIVVCSAAASG 712
>sp|P35884|TRA2_THIFE Transposase for insertion sequence element IST2
Length = 296
Score = 32.7 bits (73), Expect = 1.5
Identities = 18/63 (28%), Positives = 29/63 (46%), Gaps = 9/63 (14%)
Frame = +3
Query: 576 MIGREVMYDTPPSGHDPRIMV---------APPGMVLVQPGMSHHDQNWVHLNNTLTRRG 728
++GR +Y+ PP G DPRI + +V+V G+ +W+ + L RG
Sbjct: 47 LVGRRYLYE-PPCGEDPRICLLVIIGVTAEGKKELVMVSDGLRESKASWLEILRDLQARG 105
Query: 729 TPT 737
T
Sbjct: 106 LET 108
>sp|Q871U2|ATG7_NEUCR Autophagy-related protein 7 (Autophagy-related E1-like-activating
enzyme atg-7)
Length = 699
Score = 31.6 bits (70), Expect = 3.4
Identities = 20/66 (30%), Positives = 22/66 (33%)
Frame = +3
Query: 33 APGPASLPTGSLLRQNTNQMHHPAQYCPPQYAPIPQQMYYTGGNGFVYPQCSYMVSPXXX 212
AP P S TGS + + HP P Q G YPQCS P
Sbjct: 581 APAPVSTGTGSAVSYERDPPDHPLGLVPHQVRGFLSNFQNMVIRGKSYPQCSACSKPILD 640
Query: 213 XXXTGG 230
GG
Sbjct: 641 AYKEGG 646
>sp|P15392|CP2A4_MOUSE Cytochrome P450 2A4 (CYPIIA4) (Testosterone 15-alpha-hydroxylase)
(P450-15-alpha) (P450-IIA3.1)
Length = 494
Score = 31.2 bits (69), Expect = 4.5
Identities = 14/37 (37%), Positives = 21/37 (56%), Gaps = 1/37 (2%)
Frame = +3
Query: 27 KIAPGPASLP-TGSLLRQNTNQMHHPAQYCPPQYAPI 134
K+ PGP LP G+ L+ NT QM++ +Y P+
Sbjct: 32 KLPPGPTPLPFVGNFLQLNTEQMYNSLMKISQRYGPV 68
>sp|P20852|CP2A5_MOUSE Cytochrome P450 2A5 (CYPIIA5) (Coumarin 7-hydroxylase)
(P450-15-COH) (P450-IIA3.2)
Length = 494
Score = 30.8 bits (68), Expect = 5.9
Identities = 14/37 (37%), Positives = 21/37 (56%), Gaps = 1/37 (2%)
Frame = +3
Query: 27 KIAPGPASLP-TGSLLRQNTNQMHHPAQYCPPQYAPI 134
K+ PGP LP G+ L+ NT QM++ +Y P+
Sbjct: 32 KLPPGPTPLPFIGNFLQLNTEQMYNSLMKISQRYGPV 68
>sp|P11837|NIMA_EMENI G2-specific protein kinase nimA (Never in mitosis)
Length = 699
Score = 30.8 bits (68), Expect = 5.9
Identities = 15/46 (32%), Positives = 22/46 (47%)
Frame = +3
Query: 9 PAVTYYKIAPGPASLPTGSLLRQNTNQMHHPAQYCPPQYAPIPQQM 146
P+ T K+ P P P+ LLRQNT + PP + P ++
Sbjct: 520 PSPTRPKVKPDPFKAPSRPLLRQNTTALMQKLSTQPPIFPANPSRL 565
>sp|P41817|CUP9_YEAST Homeobox protein CUP9
Length = 306
Score = 30.8 bits (68), Expect = 5.9
Identities = 28/124 (22%), Positives = 50/124 (40%), Gaps = 1/124 (0%)
Frame = +3
Query: 69 LRQNTNQMHHPAQYCPPQYAPIPQQMYYTGGNGFVYPQCSYMVSPXXXXXXTGGSGSHA- 245
LR +T + ++PA PQ+ I +GG S +P T + S A
Sbjct: 51 LRSSTEEQNYPAPVLLPQHHSIAYPAINSGGT-------STTATPTASTVETSKTSSSAM 103
Query: 246 TISNQGGSGQQMKQEFNDMRSQDGGESVYSYFSQTSNAGVPRHDLVHGTVEAGSQTINSN 425
+Q GS ++ K +D + +Y ++ +AG + VE+ S+ ++
Sbjct: 104 DTQSQYGSSKKSKSASDDAKPCYKSAPIYEIINKEKDAGAQYNRPFSDFVESKSRRKQNS 163
Query: 426 GTGS 437
G S
Sbjct: 164 GRRS 167
>sp|Q8WXX7|AUTS2_HUMAN Autism susceptibility gene 2 protein
Length = 1259
Score = 30.8 bits (68), Expect = 5.9
Identities = 30/115 (26%), Positives = 44/115 (38%), Gaps = 7/115 (6%)
Frame = +3
Query: 6 PPAVTYYKIA-PGPASLPTGSLLRQNTNQM------HHPAQYCPPQYAPIPQQMYYTGGN 164
PP ++++ A P P SLP S L T + HHP + PP P P + T G+
Sbjct: 419 PPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPL--TSGS 476
Query: 165 GFVYPQCSYMVSPXXXXXXTGGSGSHATISNQGGSGQQMKQEFNDMRSQDGGESV 329
G + +T S Q Q++ F +S D G S+
Sbjct: 477 -----------------LQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASL 514
>sp|Q02447|SP3_HUMAN Transcription factor Sp3 (SPR-2)
Length = 781
Score = 30.8 bits (68), Expect = 5.9
Identities = 22/104 (21%), Positives = 41/104 (39%)
Frame = +3
Query: 252 SNQGGSGQQMKQEFNDMRSQDGGESVYSYFSQTSNAGVPRHDLVHGTVEAGSQTINSNGT 431
S+ G Q ++S DG + + + N G+ + + +QT+ ++GT
Sbjct: 160 SSNGTVSSVQYQVIPQIQSADGQQVQIGFTGSSDNGGINQESSQIQIIPGSNQTLLASGT 219
Query: 432 GSASXXXXXXXXXXTNHSGITLSENSDNCSPQPVKMIPRMGYPG 563
SA+ G+ + +S Q V +P +G PG
Sbjct: 220 PSANIQNLIPQTGQVQVQGVAIGGSSFPGQTQVVANVP-LGLPG 262
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 121,480,140
Number of Sequences: 369166
Number of extensions: 2777537
Number of successful extensions: 8140
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 7603
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8120
length of database: 68,354,980
effective HSP length: 111
effective length of database: 47,849,395
effective search space used: 9904824765
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)